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Volumn 124, Issue 5, 2009, Pages 1088-1098

Mutation of tyrosine 145 of lymphocyte cytosolic protein 2 protects mice from anaphylaxis and arthritis

Author keywords

arthritis; Fc receptors; integrins; localized Shwartzman reaction; Mast cells; neutrophils; passive systemic anaphylaxis; signal transduction; SLP 76

Indexed keywords

LYMPHOCYTE CYTOSOLIC PROTEIN 2; PHENYLALANINE; PROTEIN; TYROSINE; UNCLASSIFIED DRUG;

EID: 71749113276     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2009.08.038     Document Type: Article
Times cited : (14)

References (78)
  • 1
    • 0035043710 scopus 로고    scopus 로고
    • The neutrophil: function and regulation in innate and humoral immunity
    • Burg N.D., and Pillinger M.H. The neutrophil: function and regulation in innate and humoral immunity. Clin Immunol 99 (2001) 7-17
    • (2001) Clin Immunol , vol.99 , pp. 7-17
    • Burg, N.D.1    Pillinger, M.H.2
  • 2
    • 33344470236 scopus 로고    scopus 로고
    • Integrated signalling pathways for mast-cell activation
    • Gilfillan A.M., and Tkaczyk C. Integrated signalling pathways for mast-cell activation. Nat Rev 6 (2006) 218-230
    • (2006) Nat Rev , vol.6 , pp. 218-230
    • Gilfillan, A.M.1    Tkaczyk, C.2
  • 3
    • 40049101678 scopus 로고    scopus 로고
    • IgE in allergy and asthma today
    • Gould H.J., and Sutton B.J. IgE in allergy and asthma today. Nat Rev 8 (2008) 205-217
    • (2008) Nat Rev , vol.8 , pp. 205-217
    • Gould, H.J.1    Sutton, B.J.2
  • 4
    • 0036342372 scopus 로고    scopus 로고
    • Role of the neutrophil in septic shock and the adult respiratory distress syndrome
    • Aldridge A.J. Role of the neutrophil in septic shock and the adult respiratory distress syndrome. Eur J Surg 168 (2002) 204-214
    • (2002) Eur J Surg , vol.168 , pp. 204-214
    • Aldridge, A.J.1
  • 5
    • 0035423403 scopus 로고    scopus 로고
    • Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis
    • Wipke B.T., and Allen P.M. Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis. J Immunol 167 (2001) 1601-1608
    • (2001) J Immunol , vol.167 , pp. 1601-1608
    • Wipke, B.T.1    Allen, P.M.2
  • 6
    • 0033604543 scopus 로고    scopus 로고
    • Signalling through the high-affinity IgE receptor Fc epsilonRI
    • Turner H., and Kinet J.P. Signalling through the high-affinity IgE receptor Fc epsilonRI. Nature 402 suppl (1999) B24-B30
    • (1999) Nature , vol.402 , Issue.SUPPL
    • Turner, H.1    Kinet, J.P.2
  • 7
    • 0036201996 scopus 로고    scopus 로고
    • The diverse effects of mast cell mediators
    • Hines C. The diverse effects of mast cell mediators. Clin Rev Allergy Immunol 22 (2002) 149-160
    • (2002) Clin Rev Allergy Immunol , vol.22 , pp. 149-160
    • Hines, C.1
  • 9
    • 0032781554 scopus 로고    scopus 로고
    • Integrin signalling in neutrophils and macrophages
    • Berton G., and Lowell C.A. Integrin signalling in neutrophils and macrophages. Cell Signal 11 (1999) 621-635
    • (1999) Cell Signal , vol.11 , pp. 621-635
    • Berton, G.1    Lowell, C.A.2
  • 10
    • 34447337993 scopus 로고    scopus 로고
    • Compartmentalization of ITAM and integrin signaling by adapter molecules
    • Bezman N., and Koretzky G.A. Compartmentalization of ITAM and integrin signaling by adapter molecules. Immunol Rev 218 (2007) 9-28
    • (2007) Immunol Rev , vol.218 , pp. 9-28
    • Bezman, N.1    Koretzky, G.A.2
  • 11
    • 0037318720 scopus 로고    scopus 로고
    • Adaptors as central mediators of signal transduction in immune cells
    • Jordan M.S., Singer A.L., and Koretzky G.A. Adaptors as central mediators of signal transduction in immune cells. Nat Immunol 4 (2003) 110-116
    • (2003) Nat Immunol , vol.4 , pp. 110-116
    • Jordan, M.S.1    Singer, A.L.2    Koretzky, G.A.3
  • 12
    • 3042615397 scopus 로고    scopus 로고
    • Src-family kinases: rheostats of immune cell signaling
    • Lowell C.A. Src-family kinases: rheostats of immune cell signaling. Mol Immunol 41 (2004) 631-643
    • (2004) Mol Immunol , vol.41 , pp. 631-643
    • Lowell, C.A.1
  • 13
    • 33846295127 scopus 로고    scopus 로고
    • Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs
    • Mocsai A., Abram C.L., Jakus Z., Hu Y., Lanier L.L., and Lowell C.A. Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs. Nat Immunol 7 (2006) 1326-1333
    • (2006) Nat Immunol , vol.7 , pp. 1326-1333
    • Mocsai, A.1    Abram, C.L.2    Jakus, Z.3    Hu, Y.4    Lanier, L.L.5    Lowell, C.A.6
  • 15
    • 33947620178 scopus 로고    scopus 로고
    • Loss of SLP-76 expression within myeloid cells confers resistance to neutrophil-mediated tissue damage while maintaining effective bacterial killing
    • Clemens R.A., Lenox L.E., Kambayashi T., Bezman N., Maltzman J.S., Nichols K.E., et al. Loss of SLP-76 expression within myeloid cells confers resistance to neutrophil-mediated tissue damage while maintaining effective bacterial killing. J Immunol 178 (2007) 4606-4614
    • (2007) J Immunol , vol.178 , pp. 4606-4614
    • Clemens, R.A.1    Lenox, L.E.2    Kambayashi, T.3    Bezman, N.4    Maltzman, J.S.5    Nichols, K.E.6
  • 16
    • 0037379217 scopus 로고    scopus 로고
    • Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cells
    • Kettner A., Pivniouk V., Kumar L., Falet H., Lee J.S., Mulligan R., et al. Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cells. Mol Cell Biol 23 (2003) 2395-2406
    • (2003) Mol Cell Biol , vol.23 , pp. 2395-2406
    • Kettner, A.1    Pivniouk, V.2    Kumar, L.3    Falet, H.4    Lee, J.S.5    Mulligan, R.6
  • 18
    • 0036888683 scopus 로고    scopus 로고
    • Molecular adapters in Fc(epsilon)RI signaling and the allergic response
    • Rivera J. Molecular adapters in Fc(epsilon)RI signaling and the allergic response. Curr Opin Immunol 14 (2002) 688-693
    • (2002) Curr Opin Immunol , vol.14 , pp. 688-693
    • Rivera, J.1
  • 19
    • 2442700314 scopus 로고    scopus 로고
    • Differential requirement for adapter proteins Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and adhesion- and degranulation-promoting adapter protein in FcepsilonRI signaling and mast cell function
    • Wu J.N., Jordan M.S., Silverman M.A., Peterson E.J., and Koretzky G.A. Differential requirement for adapter proteins Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and adhesion- and degranulation-promoting adapter protein in FcepsilonRI signaling and mast cell function. J Immunol 172 (2004) 6768-6774
    • (2004) J Immunol , vol.172 , pp. 6768-6774
    • Wu, J.N.1    Jordan, M.S.2    Silverman, M.A.3    Peterson, E.J.4    Koretzky, G.A.5
  • 20
    • 0000082758 scopus 로고    scopus 로고
    • Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function
    • Bubeck Wardenburg J., Fu C., Jackman J.K., Flotow H., Wilkinson S.E., Williams D.H., et al. Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function. J Biol Chem 271 (1996) 19641-19644
    • (1996) J Biol Chem , vol.271 , pp. 19641-19644
    • Bubeck Wardenburg, J.1    Fu, C.2    Jackman, J.K.3    Flotow, H.4    Wilkinson, S.E.5    Williams, D.H.6
  • 21
    • 0030293529 scopus 로고    scopus 로고
    • Tyrosines 113, 128, and 145 of SLP-76 are required for optimal augmentation of NFAT promoter activity
    • Fang N., Motto D.G., Ross S.E., and Koretzky G.A. Tyrosines 113, 128, and 145 of SLP-76 are required for optimal augmentation of NFAT promoter activity. J Immunol 157 (1996) 3769-3773
    • (1996) J Immunol , vol.157 , pp. 3769-3773
    • Fang, N.1    Motto, D.G.2    Ross, S.E.3    Koretzky, G.A.4
  • 23
    • 40449106468 scopus 로고    scopus 로고
    • Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76
    • Jordan M.S., Smith J.E., Burns J.C., Austin J.E., Nichols K.E., Aschenbrenner A.C., et al. Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76. Immunity 28 (2008) 359-369
    • (2008) Immunity , vol.28 , pp. 359-369
    • Jordan, M.S.1    Smith, J.E.2    Burns, J.C.3    Austin, J.E.4    Nichols, K.E.5    Aschenbrenner, A.C.6
  • 24
    • 0032540906 scopus 로고    scopus 로고
    • Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development
    • Clements J.L., Yang B., Ross-Barta S.E., Eliason S.L., Hrstka R.F., Williamson R.A., et al. Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development. Science 281 (1998) 416-419
    • (1998) Science , vol.281 , pp. 416-419
    • Clements, J.L.1    Yang, B.2    Ross-Barta, S.E.3    Eliason, S.L.4    Hrstka, R.F.5    Williamson, R.A.6
  • 25
    • 33644541095 scopus 로고    scopus 로고
    • Disruption of SLP-76 interaction with Gads inhibits dynamic clustering of SLP-76 and FcepsilonRI signaling in mast cells
    • Silverman M.A., Shoag J., Wu J., and Koretzky G.A. Disruption of SLP-76 interaction with Gads inhibits dynamic clustering of SLP-76 and FcepsilonRI signaling in mast cells. Mol Cell Biol 26 (2006) 1826-1838
    • (2006) Mol Cell Biol , vol.26 , pp. 1826-1838
    • Silverman, M.A.1    Shoag, J.2    Wu, J.3    Koretzky, G.A.4
  • 26
    • 0142190783 scopus 로고    scopus 로고
    • G-protein-coupled receptor signaling in Syk-deficient neutrophils and mast cells
    • Mocsai A., Zhang H., Jakus Z., Kitaura J., Kawakami T., and Lowell C.A. G-protein-coupled receptor signaling in Syk-deficient neutrophils and mast cells. Blood 101 (2003) 4155-4163
    • (2003) Blood , vol.101 , pp. 4155-4163
    • Mocsai, A.1    Zhang, H.2    Jakus, Z.3    Kitaura, J.4    Kawakami, T.5    Lowell, C.A.6
  • 27
    • 0030008394 scopus 로고    scopus 로고
    • Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions
    • Lowell C.A., Fumagalli L., and Berton G. Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions. J Cell Biol 133 (1996) 895-910
    • (1996) J Cell Biol , vol.133 , pp. 895-910
    • Lowell, C.A.1    Fumagalli, L.2    Berton, G.3
  • 28
    • 33748666884 scopus 로고    scopus 로고
    • Evidence for the requirement of ITAM domains but not SLP-76/Gads interaction for integrin signaling in hematopoietic cells
    • Abtahian F., Bezman N., Clemens R., Sebzda E., Cheng L., Shattil S.J., et al. Evidence for the requirement of ITAM domains but not SLP-76/Gads interaction for integrin signaling in hematopoietic cells. Mol Cell Biol 26 (2006) 6936-6949
    • (2006) Mol Cell Biol , vol.26 , pp. 6936-6949
    • Abtahian, F.1    Bezman, N.2    Clemens, R.3    Sebzda, E.4    Cheng, L.5    Shattil, S.J.6
  • 29
    • 57549112764 scopus 로고    scopus 로고
    • Monach PA MD, Benoist C. The K/BxN arthritis model. Curr Protoc Immunol 2008. Chapter 15:Unit 15.22.
    • Monach PA MD, Benoist C. The K/BxN arthritis model. Curr Protoc Immunol 2008. Chapter 15:Unit 15.22.
  • 30
    • 0032211713 scopus 로고    scopus 로고
    • Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76
    • Bubeck Wardenburg J., Pappu R., Bu J.Y., Mayer B., Chernoff J., Straus D., et al. Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76. Immunity 9 (1998) 607-616
    • (1998) Immunity , vol.9 , pp. 607-616
    • Bubeck Wardenburg, J.1    Pappu, R.2    Bu, J.Y.3    Mayer, B.4    Chernoff, J.5    Straus, D.6
  • 31
    • 0030906543 scopus 로고    scopus 로고
    • Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2
    • Raab M., da Silva A.J., Findell P.R., and Rudd C.E. Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2. Immunity 6 (1997) 155-164
    • (1997) Immunity , vol.6 , pp. 155-164
    • Raab, M.1    da Silva, A.J.2    Findell, P.R.3    Rudd, C.E.4
  • 32
    • 0029658306 scopus 로고    scopus 로고
    • p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells
    • Tuosto L., Michel F., and Acuto O. p95vav associates with tyrosine-phosphorylated SLP-76 in antigen-stimulated T cells. J Exp Med 184 (1996) 1161-1166
    • (1996) J Exp Med , vol.184 , pp. 1161-1166
    • Tuosto, L.1    Michel, F.2    Acuto, O.3
  • 33
    • 0001584956 scopus 로고    scopus 로고
    • Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation
    • Wu J., Motto D.G., Koretzky G.A., and Weiss A. Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation. Immunity 4 (1996) 593-602
    • (1996) Immunity , vol.4 , pp. 593-602
    • Wu, J.1    Motto, D.G.2    Koretzky, G.A.3    Weiss, A.4
  • 34
    • 0032910208 scopus 로고    scopus 로고
    • Association of Nck with tyrosine-phosphorylated SLP-76 in activated T lymphocytes
    • Wunderlich L., Farago A., Downward J., and Buday L. Association of Nck with tyrosine-phosphorylated SLP-76 in activated T lymphocytes. Eur J Immunol 29 (1999) 1068-1075
    • (1999) Eur J Immunol , vol.29 , pp. 1068-1075
    • Wunderlich, L.1    Farago, A.2    Downward, J.3    Buday, L.4
  • 35
    • 0034695633 scopus 로고    scopus 로고
    • Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade
    • Bunnell S.C., Diehn M., Yaffe M.B., Findell P.R., Cantley L.C., and Berg L.J. Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade. J Biol Chem 275 (2000) 2219-2230
    • (2000) J Biol Chem , vol.275 , pp. 2219-2230
    • Bunnell, S.C.1    Diehn, M.2    Yaffe, M.B.3    Findell, P.R.4    Cantley, L.C.5    Berg, L.J.6
  • 38
    • 42449155517 scopus 로고    scopus 로고
    • Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation
    • von Kockritz-Blickwede M., Goldmann O., Thulin P., Heinemann K., Norrby-Teglund A., Rohde M., et al. Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation. Blood 111 (2008) 3070-3080
    • (2008) Blood , vol.111 , pp. 3070-3080
    • von Kockritz-Blickwede, M.1    Goldmann, O.2    Thulin, P.3    Heinemann, K.4    Norrby-Teglund, A.5    Rohde, M.6
  • 39
  • 40
    • 7644221446 scopus 로고    scopus 로고
    • Phosphatase inhibition potentiates IL-6 production by mast cells in response to FcepsilonRI-mediated activation: involvement of p38 MAPK
    • Boudreau R.T., Hoskin D.W., and Lin T.J. Phosphatase inhibition potentiates IL-6 production by mast cells in response to FcepsilonRI-mediated activation: involvement of p38 MAPK. J Leukoc Biol 76 (2004) 1075-1081
    • (2004) J Leukoc Biol , vol.76 , pp. 1075-1081
    • Boudreau, R.T.1    Hoskin, D.W.2    Lin, T.J.3
  • 41
    • 0033565790 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of Vav stimulates IL-6 production in mast cells by a Rac/c-Jun N-terminal kinase-dependent pathway
    • Song J.S., Haleem-Smith H., Arudchandran R., Gomez J., Scott P.M., Mill J.F., et al. Tyrosine phosphorylation of Vav stimulates IL-6 production in mast cells by a Rac/c-Jun N-terminal kinase-dependent pathway. J Immunol 163 (1999) 802-810
    • (1999) J Immunol , vol.163 , pp. 802-810
    • Song, J.S.1    Haleem-Smith, H.2    Arudchandran, R.3    Gomez, J.4    Scott, P.M.5    Mill, J.F.6
  • 42
    • 67650716492 scopus 로고    scopus 로고
    • The ins and outs of leukocyte integrin signaling
    • Abram C.L., and Lowell C.A. The ins and outs of leukocyte integrin signaling. Annu Rev Immunol 27 (2009) 339-362
    • (2009) Annu Rev Immunol , vol.27 , pp. 339-362
    • Abram, C.L.1    Lowell, C.A.2
  • 43
    • 49249112051 scopus 로고    scopus 로고
    • Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo
    • Bezman N.A., Lian L., Abrams C.S., Brass L.F., Kahn M.L., Jordan M.S., et al. Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo. J Exp Med 205 (2008) 1775-1788
    • (2008) J Exp Med , vol.205 , pp. 1775-1788
    • Bezman, N.A.1    Lian, L.2    Abrams, C.S.3    Brass, L.F.4    Kahn, M.L.5    Jordan, M.S.6
  • 44
    • 0026504542 scopus 로고
    • Interactions of leukocyte integrins with intercellular adhesion molecule 1 in the production of inflammatory vascular injury in vivo. The Shwartzman reaction revisited
    • Argenbright L.W., and Barton R.W. Interactions of leukocyte integrins with intercellular adhesion molecule 1 in the production of inflammatory vascular injury in vivo. The Shwartzman reaction revisited. J Clin Invest 89 (1992) 259-272
    • (1992) J Clin Invest , vol.89 , pp. 259-272
    • Argenbright, L.W.1    Barton, R.W.2
  • 45
    • 0142158261 scopus 로고
    • Inhibition of the local hemorrhagic Shwartzman reaction by a polypeptide possessing potent antiprotease activity
    • Halpern B.N. Inhibition of the local hemorrhagic Shwartzman reaction by a polypeptide possessing potent antiprotease activity. Proc Soc Exp Biol Med 115 (1964) 273-276
    • (1964) Proc Soc Exp Biol Med , vol.115 , pp. 273-276
    • Halpern, B.N.1
  • 46
    • 33747150762 scopus 로고    scopus 로고
    • Mac-1 signaling via Src-family and Syk kinases results in elastase-dependent thrombohemorrhagic vasculopathy
    • Hirahashi J., Mekala D., Van Ziffle J., Xiao L., Saffaripour S., Wagner D.D., et al. Mac-1 signaling via Src-family and Syk kinases results in elastase-dependent thrombohemorrhagic vasculopathy. Immunity 25 (2006) 271-283
    • (2006) Immunity , vol.25 , pp. 271-283
    • Hirahashi, J.1    Mekala, D.2    Van Ziffle, J.3    Xiao, L.4    Saffaripour, S.5    Wagner, D.D.6
  • 48
    • 0036884551 scopus 로고    scopus 로고
    • The role of FcgammaR signaling in the K/B x N serum transfer model of arthritis
    • Corr M., and Crain B. The role of FcgammaR signaling in the K/B x N serum transfer model of arthritis. J Immunol 169 (2002) 6604-6609
    • (2002) J Immunol , vol.169 , pp. 6604-6609
    • Corr, M.1    Crain, B.2
  • 49
    • 51849134594 scopus 로고    scopus 로고
    • Vav/phospholipase Cgamma2-mediated control of a neutrophil-dependent murine model of rheumatoid arthritis
    • Cremasco V., Graham D.B., Novack D.V., Swat W., and Faccio R. Vav/phospholipase Cgamma2-mediated control of a neutrophil-dependent murine model of rheumatoid arthritis. Arthritis Rheum 58 (2008) 2712-2722
    • (2008) Arthritis Rheum , vol.58 , pp. 2712-2722
    • Cremasco, V.1    Graham, D.B.2    Novack, D.V.3    Swat, W.4    Faccio, R.5
  • 50
    • 63449112694 scopus 로고    scopus 로고
    • Critical role of phospholipase Cgamma2 in integrin and Fc receptor-mediated neutrophil functions and the effector phase of autoimmune arthritis
    • Jakus Z., Simon E., Frommhold D., Sperandio M., and Mocsai A. Critical role of phospholipase Cgamma2 in integrin and Fc receptor-mediated neutrophil functions and the effector phase of autoimmune arthritis. J Exp Med 206 (2009) 577-593
    • (2009) J Exp Med , vol.206 , pp. 577-593
    • Jakus, Z.1    Simon, E.2    Frommhold, D.3    Sperandio, M.4    Mocsai, A.5
  • 52
    • 0037031680 scopus 로고    scopus 로고
    • Mast cells: a cellular link between autoantibodies and inflammatory arthritis
    • Lee D.M., Friend D.S., Gurish M.F., Benoist C., Mathis D., and Brenner M.B. Mast cells: a cellular link between autoantibodies and inflammatory arthritis. Science 297 (2002) 1689-1692
    • (2002) Science , vol.297 , pp. 1689-1692
    • Lee, D.M.1    Friend, D.S.2    Gurish, M.F.3    Benoist, C.4    Mathis, D.5    Brenner, M.B.6
  • 54
    • 27644470548 scopus 로고    scopus 로고
    • A crucial role for macrophages in the pathology of K/B x N serum-induced arthritis
    • Solomon S., Rajasekaran N., Jeisy-Walder E., Snapper S.B., and Illges H. A crucial role for macrophages in the pathology of K/B x N serum-induced arthritis. Eur J Immunol 35 (2005) 3064-3073
    • (2005) Eur J Immunol , vol.35 , pp. 3064-3073
    • Solomon, S.1    Rajasekaran, N.2    Jeisy-Walder, E.3    Snapper, S.B.4    Illges, H.5
  • 56
    • 0033118675 scopus 로고    scopus 로고
    • From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins
    • Korganow A.S., Ji H., Mangialaio S., Duchatelle V., Pelanda R., Martin T., et al. From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins. Immunity 10 (1999) 451-461
    • (1999) Immunity , vol.10 , pp. 451-461
    • Korganow, A.S.1    Ji, H.2    Mangialaio, S.3    Duchatelle, V.4    Pelanda, R.5    Martin, T.6
  • 58
    • 0033607499 scopus 로고    scopus 로고
    • Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme
    • Matsumoto I., Staub A., Benoist C., and Mathis D. Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme. Science 286 (1999) 1732-1735
    • (1999) Science , vol.286 , pp. 1732-1735
    • Matsumoto, I.1    Staub, A.2    Benoist, C.3    Mathis, D.4
  • 59
    • 0032550335 scopus 로고    scopus 로고
    • Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production
    • Hata D., Kawakami Y., Inagaki N., Lantz C.S., Kitamura T., Khan W.N., et al. Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production. J Exp Med 187 (1998) 1235-1247
    • (1998) J Exp Med , vol.187 , pp. 1235-1247
    • Hata, D.1    Kawakami, Y.2    Inagaki, N.3    Lantz, C.S.4    Kitamura, T.5    Khan, W.N.6
  • 60
    • 0032079898 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase-mediated interleukin-2 gene activation in mast cells. Dependence on the c-Jun N-terminal kinase activation pathway
    • Hata D., Kitaura J., Hartman S.E., Kawakami Y., Yokota T., and Kawakami T. Bruton's tyrosine kinase-mediated interleukin-2 gene activation in mast cells. Dependence on the c-Jun N-terminal kinase activation pathway. J Biol Chem 273 (1998) 10979-10987
    • (1998) J Biol Chem , vol.273 , pp. 10979-10987
    • Hata, D.1    Kitaura, J.2    Hartman, S.E.3    Kawakami, Y.4    Yokota, T.5    Kawakami, T.6
  • 61
    • 0032529221 scopus 로고    scopus 로고
    • Multiple signaling pathways for the activation of JNK in mast cells: involvement of Bruton's tyrosine kinase, protein kinase C, and JNK kinases, SEK1 and MKK7
    • Kawakami Y., Hartman S.E., Holland P.M., Cooper J.A., and Kawakami T. Multiple signaling pathways for the activation of JNK in mast cells: involvement of Bruton's tyrosine kinase, protein kinase C, and JNK kinases, SEK1 and MKK7. J Immunol 161 (1998) 1795-1802
    • (1998) J Immunol , vol.161 , pp. 1795-1802
    • Kawakami, Y.1    Hartman, S.E.2    Holland, P.M.3    Cooper, J.A.4    Kawakami, T.5
  • 62
  • 63
    • 71849094777 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase-dependent activation of Btk is required for optimal eicosanoid production and generation of reactive oxygen species in antigen-stimulated mast cells
    • Kuehn H.S., Swindle E.J., Kim M.S., Beaven M.A., Metcalfe D.D., and Gilfillan A.M. The phosphoinositide 3-kinase-dependent activation of Btk is required for optimal eicosanoid production and generation of reactive oxygen species in antigen-stimulated mast cells. J Immunol 181 (2008) 7706-7712
    • (2008) J Immunol , vol.181 , pp. 7706-7712
    • Kuehn, H.S.1    Swindle, E.J.2    Kim, M.S.3    Beaven, M.A.4    Metcalfe, D.D.5    Gilfillan, A.M.6
  • 64
    • 12444253525 scopus 로고    scopus 로고
    • Preferential signaling and induction of allergy-promoting lymphokines upon weak stimulation of the high affinity IgE receptor on mast cells
    • Gonzalez-Espinosa C., Odom S., Olivera A., Hobson J.P., Martinez M.E., Oliveira-Dos-Santos A., et al. Preferential signaling and induction of allergy-promoting lymphokines upon weak stimulation of the high affinity IgE receptor on mast cells. J Exp Med 197 (2003) 1453-1465
    • (2003) J Exp Med , vol.197 , pp. 1453-1465
    • Gonzalez-Espinosa, C.1    Odom, S.2    Olivera, A.3    Hobson, J.P.4    Martinez, M.E.5    Oliveira-Dos-Santos, A.6
  • 66
    • 0036554394 scopus 로고    scopus 로고
    • Signaling to localized degranulation in neutrophils adherent to immune complexes
    • Naucler C., Grinstein S., Sundler R., and Tapper H. Signaling to localized degranulation in neutrophils adherent to immune complexes. J Leukoc Biol 71 (2002) 701-710
    • (2002) J Leukoc Biol , vol.71 , pp. 701-710
    • Naucler, C.1    Grinstein, S.2    Sundler, R.3    Tapper, H.4
  • 67
    • 0028102054 scopus 로고
    • Role of protein phosphorylation in the degranulation of electropermeabilized human neutrophils
    • Niessen H.W., and Verhoeven A.J. Role of protein phosphorylation in the degranulation of electropermeabilized human neutrophils. Biochim Biophys Acta 1223 (1994) 267-273
    • (1994) Biochim Biophys Acta , vol.1223 , pp. 267-273
    • Niessen, H.W.1    Verhoeven, A.J.2
  • 68
    • 33745559712 scopus 로고    scopus 로고
    • Neutrophil serine proteases: specific regulators of inflammation
    • Pham C.T. Neutrophil serine proteases: specific regulators of inflammation. Nat Rev 6 (2006) 541-550
    • (2006) Nat Rev , vol.6 , pp. 541-550
    • Pham, C.T.1
  • 69
    • 0025703624 scopus 로고
    • Ca2(+)-induced secretion by electropermeabilized human neutrophils. The roles of Ca2+, nucleotides and protein kinase C
    • Smolen J.E., and Sandborg R.R. Ca2(+)-induced secretion by electropermeabilized human neutrophils. The roles of Ca2+, nucleotides and protein kinase C. Biochim Biophys Acta 1052 (1990) 133-142
    • (1990) Biochim Biophys Acta , vol.1052 , pp. 133-142
    • Smolen, J.E.1    Sandborg, R.R.2
  • 71
    • 33644688070 scopus 로고    scopus 로고
    • ITAM-based signaling beyond the adaptive immune response
    • Fodor S., Jakus Z., and Mocsai A. ITAM-based signaling beyond the adaptive immune response. Immunol Lett 104 (2006) 29-37
    • (2006) Immunol Lett , vol.104 , pp. 29-37
    • Fodor, S.1    Jakus, Z.2    Mocsai, A.3
  • 72
    • 55749109709 scopus 로고    scopus 로고
    • Fc{gamma}R-stimulated activation of the NADPH oxidase: phosphoinositide-binding protein p40phox regulates NADPH oxidase activity after enzyme assembly on the phagosome
    • Tian W., Li X.J., Stull N.D., Ming W., Suh C.I., Bissonnette S.A., et al. Fc{gamma}R-stimulated activation of the NADPH oxidase: phosphoinositide-binding protein p40phox regulates NADPH oxidase activity after enzyme assembly on the phagosome. Blood 112 (2008) 3867-3877
    • (2008) Blood , vol.112 , pp. 3867-3877
    • Tian, W.1    Li, X.J.2    Stull, N.D.3    Ming, W.4    Suh, C.I.5    Bissonnette, S.A.6
  • 73
    • 2942625705 scopus 로고    scopus 로고
    • Staging the initiation of autoantibody-induced arthritis: a critical role for immune complexes
    • Wipke B.T., Wang Z., Nagengast W., Reichert D.E., and Allen P.M. Staging the initiation of autoantibody-induced arthritis: a critical role for immune complexes. J Immunol 172 (2004) 7694-7702
    • (2004) J Immunol , vol.172 , pp. 7694-7702
    • Wipke, B.T.1    Wang, Z.2    Nagengast, W.3    Reichert, D.E.4    Allen, P.M.5
  • 74
    • 42949127096 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells selectively diminish systemic autoreactivity in arthritic K/BxN mice
    • Kang S.M., Jang E., Paik D.J., Jang Y.J., and Youn J. CD4+CD25+ regulatory T cells selectively diminish systemic autoreactivity in arthritic K/BxN mice. Mol Cells 25 (2008) 64-69
    • (2008) Mol Cells , vol.25 , pp. 64-69
    • Kang, S.M.1    Jang, E.2    Paik, D.J.3    Jang, Y.J.4    Youn, J.5
  • 75
    • 12344307565 scopus 로고    scopus 로고
    • NKT cells promote antibody-induced joint inflammation by suppressing transforming growth factor beta1 production
    • Kim H.Y., Kim H.J., Min H.S., Kim S., Park W.S., Park S.H., et al. NKT cells promote antibody-induced joint inflammation by suppressing transforming growth factor beta1 production. J Exp Med 201 (2005) 41-47
    • (2005) J Exp Med , vol.201 , pp. 41-47
    • Kim, H.Y.1    Kim, H.J.2    Min, H.S.3    Kim, S.4    Park, W.S.5    Park, S.H.6
  • 76
    • 33748296238 scopus 로고    scopus 로고
    • FcgammaRIII engagement provides activating signals to NKT cells in antibody-induced joint inflammation
    • Kim H.Y., Kim S., and Chung D.H. FcgammaRIII engagement provides activating signals to NKT cells in antibody-induced joint inflammation. J Clin Invest 116 (2006) 2484-2492
    • (2006) J Clin Invest , vol.116 , pp. 2484-2492
    • Kim, H.Y.1    Kim, S.2    Chung, D.H.3
  • 77
    • 0035883897 scopus 로고    scopus 로고
    • Rheumatoid arthritis
    • Lee D.M., and Weinblatt M.E. Rheumatoid arthritis. Lancet 358 (2001) 903-911
    • (2001) Lancet , vol.358 , pp. 903-911
    • Lee, D.M.1    Weinblatt, M.E.2
  • 78
    • 58149233832 scopus 로고    scopus 로고
    • Induction of autoantibody-mediated spontaneous arthritis critically depends on follicular dendritic cells
    • Victoratos P., and Kollias G. Induction of autoantibody-mediated spontaneous arthritis critically depends on follicular dendritic cells. Immunity 30 (2009) 130-142
    • (2009) Immunity , vol.30 , pp. 130-142
    • Victoratos, P.1    Kollias, G.2


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