Functions of Bruton's tyrosine kinase in mast and B cells

Journal of Leukocyte Biology

Volumn 65, Issue 3, 1999, Pages 286-290

  Kawakami, Yuko ^a   Kitaura, Jiro ^a   Hata, Daisuke ^a,b   Yao, Libo ^a,c   Kawakami, Toshiaki ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b Kishiwada City Hospital   (Japan)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Emt; Fc RI; Signal transduction; Tec

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN; IMMUNOGLOBULIN E RECEPTOR; LYMPHOCYTE ANTIGEN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MONOCLONAL ANTIBODY; PHOSPHOLIPASE C; PLECKSTRIN; PROTEIN TYROSINE KINASE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR;

B LYMPHOCYTE; B LYMPHOCYTE DIFFERENTIATION; CROSS LINKING; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE; GENE ACTIVATION; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; MAST CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

EID: 0033055034     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.65.3.286     Document Type: Review

References (46)

1. Vetrie, D., Vorechovsky, I., Sideras, P., Holland, J., Davies, A., Flinter, F., Hammarstrom, L., Kinnon, C., Levinsky, R., Bobrow, M., Smith, C. I. E., Bentley, D. R. (1993) The gene involved in X-linked agammaglobulinemia is a member of the src family of protein-tyrosine kinases. Nature 361, 226-233.
2. Tsukada, S., Saffran, D., Rawlings, D. J., Parolini, O., Allen, R. C., Klisak, I., Sparkes, R. S., Kubagawa, H., Mohandas, T., Quan, S., Belmont, J. W., Cooper, M. D., Conley, M. E., Witte, O. N. (1993) Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia. Cell 72, 279-290.
3. Yamada, N., Kawakami, Y., Kimura, H., Fukamachi, H., Baier, G., Altman, A., Kato, T., Inagaki, Y., Kawakami, T. (1993) Structure and expression of novel protein tyrosine kinases, Emb and Emt. in hematopoietic cells. Biochem. Biophys. Res. Commun. 192, 231-240.
4. Thomas, J. D., Sideras, P., Smith, C. I. E., Vorechovsky, I., Chapman, V., Paul, W. E. (1993) Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes. Science 261, 355-358.
5. Rawlings, D. J., Saffran, D. C., Tsukada, S., Largaespada, D. A., Grimaldi, J. C., Cohen, L., Mohr, R. N., Bazan, J. F., Howard, M., Copeland, N. G., Jenkins, N. A., Witte, O. N. (1993) Mutation of unique region of Bruton's tyrosine kinase in immunodieficient XID mice. Science 261, 358-361.
6. Khan, W. N., Alt, F. W., Gerstein, R. M., Malynn, B. A., Larsson, I., Rathbun, G., Davidson, L., Mueller, S., Kantor, A. B., Herzenberg, L. A., Rosen, F. S., Sideras, P. (1995) Defective B cell development and function in Btk-deficient mice. Immunity 3, 283-299.
7. Kerner, J. D., Appleby, M. W., Mohr, R. N., Chien, S., Rawlings, D. J., Maliszewski, C. R., Witte, O. N., Perlmutter, R. M. (1995) Impaired expansion of mouse B cell progenitors lacking Btk. Immunity 3, 301-312.
8. Hendriks, R. W., de Bruijn, M. F. T. R., Maas, A., Dingjan, G. M., Karis, A., Grosveld, F. (1996) inactivation of Btk by insertion of lacZ reveals defects in B cell development only past the pre-B cell stage. EMBO J. 15, 4862-4872.
9. Satterthwaite, A., Witte, O. (1996) Genetic analysis of tyrosine kinase function in B cell development. Annu. Rev. Immunol. 14, 131-154.
10. Tarakhovsky, A. (1997) Xid and Xid-like immunodeficiencies from a signaling point of view. Curr. Opin. Immunol. 9, 319-323.
11. Desiderio, S. (1997) Role of Btk in B cell development and signaling. Curr. Opin. Immunol. 9, 534-540.
12. Satterthwaite, A. B., Li, Z., Witte, O. N. (1998) Btk function in B cell development and response. Semin. Immunol. 10, 309-316.
13. Kawakami, Y., Yao, L., Tsukada, S., Witte, O. N., Kawakami, T. (1994) Tyrosine phosphorylation and activation of Bruton tyrosine kinase upon FcεRI cross-linking. Mol. Cell. Biol. 14, 5108-5113.
14. Hata, D., Kawakami, Y., Inagaki, N., Lantz, C. S., Kitamura, T., Khan, W. N., Maeda-Yamamoto, M., Miura, T., Han, W., Hartman, S. E., Yao, L., Nagai, H., Goldfeld, A. E., Alt, F. W., Galli, S. J., Witte, O. N., Kawakami, T. (1998) Involvement of Bruton's tyrosine kinase in FcεRI-depndent mast cell degranulation and cytokine production. J. Exp. Med. 187, 1235-1247.
15. Kawakami, Y., Miura, T., Bissonnette, R., Hata, D., Khan, W. N., Kitamura, T., Maeda-Yamamoto, M., Hartman, S. E., Yao, L., Alt, F. W., Kawakami, T. (1997) Brutton's tyrosine kinase regulates apoptosis and JNK/SPAK kinase acitivity. Proc. Natl. Acad. Sci. USA 91, 3938-3942.
16. Uckun, F. M., Waddick, K. G., Mahajan, S., Jun, X., Takata, M., Bolen, J., Kurosaki, T. (1996) BTK as a mediator of radiation-induced apoptosis in DT-40 lymphoma B cells. Science 273, 1096-1100.
17. Langhans-Rajasekaran, S. A., Wan, Y., Huang, X.-Y. (1995) Activation of Tsk and Btk tyrosine kinaso by G protein bg subunits. Proc. Natl. Acad. Sci. USA 92, 8601-8605.
18. Bence, K., Ma, W., Kozasa, T., Huang, X.-Y. (1997) Direct stimulation of Bruton's tyrosine kinase by Gq-protein α-subunit. Nature 389, 296-299.
19. Ma, C. Y., Huang, X. Y. (1998) Identification of the binding site for Gqα on its effector Bruton's tyrosine kinase. Proc. Natl. Acad. Sci. USA 95, 12197-12201.
20. Andreotti, A. H., Bunnell, S. C., Feng, S., Berg, L. J., Schreiber, S. L. (1997) Regulatory intramolecular association in a tyrosine kinase of the Tec family. Nature 385, 93-97.
21. cbl. Proteins 29, 545-552.
22. Cheng, G., Ye, Z.-S., Baltimore, D. (1991) Binding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interaction. Proc. Natl. Acad. Sci. USA 91, 8152-8155.
23. Cory, G. O. C., Lovering, R. C., Hinshelwood, S., MacCarthy-Morrogh, L., Levinsky, R. J., Kinnon, C. (1995) The protein product of the c-cbl protooncogene is phosphorylated after B cell receptor stimulation and binds the SH3 domain of Bruton's tyrosine kinase. J. Exp. Med. 182, 611-615.
24. Matsushita, M., Yamadori, T., Kato, S., Takemoto, Y., Inazawa, J., Baba, Y., Hashimoto, S., Sekine, S., Arai, S., Kunikata, T., Kurimoto, M., Kishimoto, T., Tsukada, (1998) Identification and characterization of a novel SH3-domain binding protein, Sab, which preferentially associates with Bruton's tyrosine kinase (Btk). Biochem. Biophys. Res. Commun. 245, 337-343.
25. Jiang, Y., Ma, W., Kozasa, T., Hattori, S., Huang, X.-Y. (1998) The G protein Gα12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain. Nature 395, 808-813.
26. Downward, J. (1998) Mechanisms and consequences of activation of protein kinase B/Akt. Curr. Opin. Cell Biol. 10, 262-267.
27. Li, Z., Wahl, M. I., Eguinoa, A., Stephens, L. R., Hawkins, P. T., Witte, O. N. (1997) Phosphatidylinositol 3-kinase-g activates Brutons' tyrosine kinase in concert with Src family kinases. Proc. Natl. Acad. Sci. USA 91, 13820-13825.
28. 3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals. EMBO J. 17, 1961-1972.
29. Rawlings, D. J., Scharenberg, A. M., Park, H., Wahl, M. I., Lin, S., Kato, R. M., Fluckiger, A.-C., Witte, O. N., Kinet, J.-P. (1996) Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases. Science 271, 822-825.
30. Mahajan, S., Fargnoli, J., Burkhardt, A. L., Kut, S. A., Saouaf, S. J., Bolen, J. B. (1995) Src family protein tyrosine kinases induce autoactivation of Bruton's tyrosine kinase. Mol. Cell. Biol. 15, 5304-5311.
31. Kurosaki, T., Kurosaki, M. (1997) Transphosphorylation of Bruton's tyrosine kinase on tyrosine 551 is critical for B cell antigen receptor function. J. Biol. Chem. 272, 15595-15598.
32. Park, H., Wahl, M. I., Afar, D. E. H., Turck, C. W., Rawlings, D. J., Tam, C., Scharenberg, A. M., Kinet, J.-P., Witte, O. N. (1996) Regulation of Btk function by a major autophosphorylation site within the SH3 domain. Immunity 4, 515-525.
33. Li, T., Tsukada, S., Satterthwaite, A., Havlik, M. H., Park, H., Takatsu, K., Witte, O. N. (1995) Activation of Bruton's tyrosine kinase (BTK) by a point mutation in its pleckstrin homology (PH) domain. Immunity 2, 451-460.
34. Li, T., Rawlings, D. J., Park, H., Kato, R. M., Witte, O. N., Satterthwaite, A. B. (1997) Constitutive membrane association potentiates activation of Bruton tyrosine kinase. Oncogene 15, 1375-1383.
35. Bolland, S., Pearse, R. N., Kurosaki, T, Ravetch, J. V. (1998) SHIP modulates immune receptor responses by regulating membrane association of Btk. Immunity 8, 509-516.
36. Yao, L., Kawakami, Y., Kawakami, T. (1994) The pleckstrin homology domain of Btk tyrosine kinase interacts with protein kinase C. Proc. Natl. Acad. Sci. USA 91, 9175-9179.
37. Yao, L., Suzuki, H., Ozawa, K., Deng, J., Lehel, C., Fukamachi, H., Anderson, W. B., Kawakami, Y., Kawakami, T. (1997) Interactions between protein kinase C and pleckstrin homology domains. Inhibition by phosphatidylinositol 4,5-bisphosphate and phorbol 12-myristate 13-acetate. J. Biol. Chem. 272, 13033-13039.
38. Leitges, M., Schmedt, C., Guinamard, R., Davoust, J., Schaal, S., Stabel, S., Tarakhovsky, A. (1996) Immunodeficiency in protein kinase Cβ-deficient mice. Science 273, 788-791.
39. 2+ following B-cell receptor activation. EMBO J. 17, 1973-1985.
40. Liu, K.-Q., Bunnel, S. C., Gurniak, C. B., Berg, L. J. (1998) T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in ltk-deficient T cells. J. Exp. Med. 187, 1721-1727.
41. Yang, W., Desiderio, S. (1997) BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement. Proc. Natl. Acad. Sci. USA 94, 604-609.
42. Takata, M., Kurosaki, T. (1996) A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-γ2. J. Exp. Med. 184, 31-40.
43. 2+ mobilization through distinct pathways. EMBO J. 15, 1341-1349.
44. Kawakami, Y., Hartman, S. E., Holland, P. M., Cooper, J. A., Kawakami, T. (1998) Multiple signaling pathways for the activation of JNK in mast cells: Involvement of Bruton's tyrosine kinase, protein kinase C, and JNK kinases, SEK1 and MKK7. J. Immunol. 161, 1795-1802.
45. Deng, J., Kawakami, Y., Hartman, S. E., Satoh, T., Kawakami, T. (1998) Involvement of Ras in Bruton's tyrosine kinase-mediated JNK activation. J. Biol. Chem. 273, 16787-16791.
46. Hata, D., Kitaura, J., Hartman, S. E., Kawakami, Y., Yokota, T., Kawakami, T. (1998) Bruton's tyrosine kinase-mediated interleukin-2 gene activation in mast cells. Dependence on the c-Jun N-terminal kinase activation pathway. J. Biol. Chem. 273, 10979-10987.