Isolation of the protein tyrosine phosphatase 1B inhibitory metabolite from the marine-derived fungus Cosmospora sp. SF-5060

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 21, 2009, Pages 6095-6097

  Seo, Changon ^a   Sohn, Jae Hak ^a   Oh, Hyuncheol ^a   Kim, Bo Yeon ^b   Ahn, Jong Seog ^b  

^a Silla University   (South Korea)

^b Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

Competitive inhibitor; Cosmospora sp.; Fungal metabolite; Marine derived fungus; Protein tyrosine phosphatase 1B (PTP1B)

Indexed keywords

AQUASTATIN A; CD45 ANTIGEN; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 2; PROTEIN TYROSINE PHOSPHATASE 1B; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; UNCLASSIFIED DRUG; URSOLIC ACID;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; COSMOSPORA; DRUG ISOLATION; DRUG PROTEIN BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME INHIBITION; FUNGUS; HYDROLYSIS; IC 50; PROTON NUCLEAR MAGNETIC RESONANCE;

BENZOATES; BINDING, COMPETITIVE; ENZYME INHIBITORS; FUNGI; GALACTOSIDES; KINETICS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 2;

COSMOSPORA; FUNGI;

EID: 71749110201     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.09.025     Document Type: Article

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