Inhibition of protein tyrosine phosphatase 1B by diterpenoids isolated from Acanthopanax koreanum

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 11, 2006, Pages 3061-3064

  Na, MinKyun ^a   Oh, Won Keun ^a   Kim, Young Ho ^b   Cai, Xing Fu ^a   Kim, SoHee ^a   Kim, Bo Yeon ^a   Ahn, Jong Seog ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chungnam National University   (South Korea)

Author keywords

Acanthopanax koreanum; Araliaceae; Diterpenoids; Non competitive inhibitor; Protein tyrosine phosphatase 1B (PTP1B)

Indexed keywords

16ALPHA HYDROXY 17 ISOVALERYLOXYKAURAN 19 OIC ACID; 16ALPHA HYDROXYKAURAN 19 OIC ACID; 16ALPHAH,17 ISOVALERYLOXYKAURAN 19 OIC ACID; 7BETA HYDROXYPIMARA 8(14),15 DIEN 19 OIC ACID; ACANTHOIC ACID; ACANTHOKOREOIC ACID A; ACANTHOL; ACANTHOPANAX KOREANUM EXTRACT; DITERPENOID; KAURENOIC ACID; PLANT EXTRACT; PROTEIN TYROSINE PHOSPHATASE 1B; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; UNCLASSIFIED DRUG;

ACANTHOPANAX; ACANTHOPANAX KOREANUM; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ISOLATION; ENZYME ACTIVITY; ENZYME INHIBITION; IC 50; NONHUMAN; PLANT ROOT;

ACANTHOPANAX; DITERPENES; MOLECULAR STRUCTURE; PROTEIN-TYROSINE-PHOSPHATASE;

ACANTHOPANAX; ARALIACEAE; ELEUTHEROCOCCUS KOREANUS;

EID: 33646046143     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.02.053     Document Type: Article

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