Suboptimal activation of protease-activated receptors enhances α 2β1 integrin-mediated platelet adhesion tocollagen

Journal of Biological Chemistry

Volumn 284, Issue 50, 2009, Pages 34640-34647

  Marjoram, Robin J ^a   Voss, Bryan ^a   Pan, Yumei ^a   Dickeson, S Kent ^a   Zutter, Mary M ^a   Hamm, Heidi E ^a   Santoro, Samuel A ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAIN COMPLEXES; COLLAGEN RECEPTORS; FIBRILLAR COLLAGENS; G PROTEIN COUPLED RECEPTORS; INTEGRINS; PHOSPHOLIPASE C; PLATELET ADHESION; PLATELET AGGREGATION; POTENT ACTIVATORS; PROTEASE ACTIVATED RECEPTORS; SHAPE CHANGE; SIGNALING CASCADES; SIGNALING MECHANISMS; SPECIFIC BINDING; THROMBIN RECEPTORS; VASCULAR INJURY;

ADHESION; AMINES; BINDING SITES; BLOOD SUBSTITUTES; CHEMICAL ACTIVATION; COLLAGEN; GRANULATION; PEPTIDES; SIGNALING;

PLATELETS;

G PROTEIN COUPLED RECEPTOR; GLYCOPROTEIN VI; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 4; VERY LATE ACTIVATION ANTIGEN 2;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN MOTIF; RAT; SIGNAL TRANSDUCTION; THROMBOCYTE ADHESION;

AMINO ACID MOTIFS; ANIMALS; BLOOD PLATELETS; CARRIER PROTEINS; COLLAGEN; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HUMANS; INTEGRIN ALPHA2BETA1; MICE; MICE, INBRED C57BL; PEPTIDES; PLATELET ADHESIVENESS; PLATELET AGGREGATION; PLATELET MEMBRANE GLYCOPROTEINS; RATS; RECEPTOR, PAR-1; RECEPTORS, COLLAGEN; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, IGG; RECEPTORS, THROMBIN; SIGNAL TRANSDUCTION; THROMBIN; TYPE C PHOSPHOLIPASES;

EID: 71749105941     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.020990     Document Type: Article

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