Changes in cholesterol biosynthetic and transport pathways after excitotoxicity

Journal of Neurochemistry

Volumn 112, Issue 1, 2010, Pages 34-41

  Kim, Ji Hyun ^a   Jittiwat, Jinatta ^a   Ong, Wei Yi ^a   Farooqui, Akhlaq A ^b   Jenner, Andrew M ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

7 ketocholesterol; ABCA1; Brain; Cholesterol biosynthesis; Cholesterol oxidation products; Kainate excitotoxicity; Lanosterol; Lathosterol; Oxysterols

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; 7 DEHYDROCHOLESTEROL; 7 OXOCHOLESTEROL; ABC TRANSPORTER A1; BETA ACTIN; CHOLESTEROL; DESMOSTEROL; EPOXIDE; KAINIC ACID; LANOSTEROL; LANOSTEROL SYNTHASE; MESSENGER RNA; PROTEIN INSIG1; PROTEIN INSIG2; STEROL 14ALPHA DEMETHYLASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; AUTOOXIDATION; BRAIN HOMOGENATE; CHOLESTEROL SYNTHESIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; EXCITOTOXICITY; GENE EXPRESSION; GLIOSIS; HIPPOCAMPUS; MALE; MASS FRAGMENTOGRAPHY; NERVE CELL LESION; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT, ACTIVE; CHOLESTEROL; EXCITATORY AMINO ACID AGONISTS; HIPPOCAMPUS; KAINIC ACID; MALE; OXIDATION-REDUCTION; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

RATTUS;

EID: 71649114650     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06449.x     Document Type: Article

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