7-Ketocholesterol enhances 1-methyl-4-phenylpyridinium-induced mitochondrial dysfunction and cell death in PC12 cells

Journal of Neural Transmission

Volumn 113, Issue 12, 2006, Pages 1877-1885

  Kim, Y J ^a   Han, J H ^a   Han, E S ^a   Lee, C S ^a  

^a Chung Ang University   (South Korea)

Author keywords

1 Methyl 4 phenylpyridinium; 7 ketocholesterol; Cell injury; Mitochondrial membrane permeability; PC12 cells

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 2 (4 CARBOXYPHENYL) 4,4,5,5 TETRAMETHYLIMIDAZOLINE 1 OXYL 3 OXIDE; 7 OXOCHOLESTEROL; ACETYLCYSTEINE; ASCORBIC ACID; CASPASE 3; CYTOCHROME C; GLUTATHIONE; MANGANESE DERIVATIVE; REACTIVE OXYGEN METABOLITE; TROLOX C;

ANIMAL CELL; ARTICLE; BRAIN MITOCHONDRION; CELL NUCLEUS; CELL STRAIN; CELL VIABILITY; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME RELEASE; MEMBRANE PERMEABILITY; MITOCHONDRIAL MEMBRANE; NERVE CELL DIFFERENTIATION; NERVE CELL LESION; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; RAT;

ANIMALS; CASPASE 3; CELL DEATH; CELL DIFFERENTIATION; CELL NUCLEUS; CELL SURVIVAL; CYTOCHROMES C; DOPAMINE AGENTS; DRUG SYNERGISM; ENZYME INHIBITORS; FLOW CYTOMETRY; GLUTATHIONE; KETOCHOLESTEROLS; MEMBRANE POTENTIALS; MITOCHONDRIA; MITOCHONDRIAL DISEASES; MPTP POISONING; PC12 CELLS; PERMEABILITY; RATS; REACTIVE OXYGEN SPECIES;

EID: 33751002074     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-006-0486-6     Document Type: Article

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