c-Abl tyrosine kinase interacts with MAVS and regulates innate immune response

FEBS Letters

Volumn 584, Issue 1, 2010, Pages 33-38

  Song, Ting ^a   Wei, Congwen ^a   Zheng, Zirui ^b   Xu, Yang ^b   Cheng, Xiaozhong ^a   Yuan, Yuan ^a   Guan, Kai ^a   Zhang, Yanhong ^a   Ma, Qingjun ^a   Shi, Wei ^b   Zhong, Hui ^a  

^a BEIJING INSTITUTE OF BIOTECHNOLOGY   (China)

^b JILIN UNIVERSITY   (China)

Author keywords

c Abl non receptor tyrosine kinase; Innate immune response; Mitochondrial antiviral signaling; RIG1 signaling

Indexed keywords

ABELSON KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERFERON REGULATORY FACTOR 3; MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN; MITOCHONDRIAL PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN MCF 7; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOREGULATION; INNATE IMMUNITY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL LINE; HUMANS; IMMUNITY, INNATE; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; NF-KAPPA B; PHOSPHORYLATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; PROTO-ONCOGENE PROTEINS C-ABL;

VESICULAR STOMATITIS VIRUS;

EID: 71649084624     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.11.025     Document Type: Article

References (28)

1. Pendergast A.M. The Abl family kinases: mechanisms of regulation and signaling. Adv. Cancer Res. 85 (2002) 51-100
2. Van Etten R.A. Cycling, stressed-out, and nervous: cellular functions of c-Abl. Trends Cell Biol. 9 (1999) 179-186
3. Plattner R., Irvin B.J., Guo S., Blackburn K., Kazlauskas A., Abraham R.T., York Y.D., and Pendergast A.M. A new link between the c-Abl tyrosine kinase and phosphoinositide signaling through PLC-gamma1. Nat. Cell Biol. 5 (2003) 309-319
4. Nagar B., Hantschel O., Young M.A., Scheffzek K., Veach D., Bornmann W., Clarkson B., Superti-Furga G., and Kuriyan J. Structural basis for the autoinhibition of c-Abl tyrosinekinase. Cell 112 (2003) 859-871
5. Welch P.J., and Wang J.Y.J. A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle. Cell 75 (1993) 779-790
6. Yukio N., Raelene J.G., and Steve G. NF-κB1 can inhibit v-Abl-induced lymphoid transformation by functioning as a negative regulator of Cyclin D1 expression. Mol. Cell. Biol. 22 (2002) 5563-5574
7. Hidehiko K., Linghu N., and Zhi-Min Y. Inactivation of NF-κB -dependent cell survival, a novel mechanism for the proapoptotic function of c-Abl. Mol. Cell. Biol. 22 (2002) 6079-6088
8. Kawai T., and Akira S. Innate immune recognition of viral infection. Nat. Immunol. 7 (2006) 131-137
9. Perry A.K., Chen G., Zheng D., Tang H., and Cheng G. The host type I interferon response to viral and bacterial infections. Cell Res. 15 (2005) 407-422
10. Akira S., and Takeda K. Toll-like receptor signaling. Nat. Rev. Immunol. 4 (2004) 499-511
11. Meylan E., and Tschopp J. Toll-like receptors and RNA helicases: two parallel ways to trigger antiviral responses. Mol. Cell 22 (2006) 561-569
12. Martinon F., and Tschopp J. NLRs join TLRs as innate sensors of pathogens. Trends Immunol. 26 (2005) 447-454
13. Jörg H.F., Richard L.F., Dana J.P., and Stephen E.G. Nod-like proteins in immunity, inflammation and disease. Nat. Immunol. 7 (2006) 1250-1257
14. Inohara N., and Nunez G. NODs: intracellular proteins involved in inflammation and apoptosis. Nat. Rev. Immunol. 3 (2003) 371-382
15. Inohara N., Chamaillard M., McDonald C., and Nunez G. NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. Annu. Rev. Biochem. 74 (2005) 355-383
16. Kumar H., Kawai T., Kato H., Sato S., Takahashi K., Coban C., Yamamoto M., Uematsu S., Ishii K.J., and Takeuchi O. Essential role of IPS-1 in innate immune responses against RNA viruses. J. Exp. Med. 203 (2006) 1795-1803
17. Kato H., Sato S., Yoneyama M., Yamamoto M., Uematsu S., Matsui K., Tsujimura T., Takeda K., Fujita T., and Takeuchi O. Cell type specific involvement of RIG-I in antiviral response. Immunity 23 (2005) 19-28
18. Kato H., Takeuchi O., Sato S., Yoneyama M., Yamamoto M., Matsui K., Uematsu S., Jung A., Kawai T., and Ishii K.J. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441 (2006) 101-105
19. Kawai T., Takahashi K., and Sato S. An adaptor triggering RIG-1 and Mda5-mediated type I interferon induction. Nat. Immunol. 6 (2005) 981-988
20. Yoneyama M., Kikuchi M., and Natsukawa T. The RNA helicase RIG-1 has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5 (2004) 730-737
21. Rashu B.S., Lijun S., Chee-Kwee E., and Zhijian J.C. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-κB and IRF3. Cell 122 (2005) 669-682
22. John H., Rongtuan L., Peyman N., and Suzanne P. MasterCARD-a priceless link to innate immunity. Trends Mol. Med. 12 (2006) 2-10
23. Liang-Guo X., Yan-Yi W., Ke-Jun H., Lian-Yun L., Zhonghe Z., and Hong-Bing S. VISA is an adaptor protein required for virus-triggered IFN-β signaling. Mol. Cell 19 (2005) 727-740
24. Xiang H., Congwen W., Ting S., Jing Y., Yanhong Z., Qingjun M., Wei S., and Hui Z. Proliferating cell nuclear antigen destabilizes c-Abl tyrosine kinase and regulates cell apoptosis in response to DNA damage. Apoptosis 14 (2009) 268-275
25. Akinori T., ZhiChao W., Myoung K.C., Hideyuki Y., Hideo N., Tatsuma B., Yan L., Makoto M., Tatsuhiko K., Kenya H., Yusuke O., and Tadatsugu T. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 448 (2007) 501-505
26. Ingvild B.J., Thuy T.N., Bjarte B., Katherine A.F., and Marit W.A. The tyrosine kinase c-Src enhances RIG-I (retinoic acid-inducible gene I)-elicited antiviral signaling. J. Biol. Chem. 284 (2009) 19122-19131
27. Beichu G., and Genhong C. Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK. J. Biol. Chem. 282 (2007) 11817-11826
28. Ryzhakov G., and Randow F. SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK. EMBO J. 26 (2007) 3180-3190