Cybrid models of Parkinson's disease show variable mitochondrial biogenesis and genotype-respiration relationships

Experimental Neurology

Volumn 220, Issue 2, 2009, Pages 374-382

  Keeney, Paula M ^a   Dunham, Lisa D ^a   Quigley, Caitlin K ^a   Morton, Stephanie L ^a   Bergquist, Kristen E ^a   Bennett Jr , James P ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Cybrid; Heteroplasmy; Mitochondrial biogenesis; Mitochondrial DNA; Parkinson's disease; respiration

Indexed keywords

MITOCHONDRIAL DNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

ADULT; AGED; ARTICLE; CELL RESPIRATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYBRID; FEMALE; GENE MUTATION; GENOTYPE; HETEROPLASMY; HUMAN; HUMAN CELL; MALE; MITOCHONDRIAL DNA DEPLETION; MITOCHONDRIAL GENOME; MITOCHONDRIAL RESPIRATION; PARKINSON DISEASE; PHENOTYPE; PRIORITY JOURNAL;

AGED; BASE PAIR MISMATCH; CELL LINE; CULTURE MEDIA; DNA PRIMERS; DNA, MITOCHONDRIAL; FEMALE; GENE DOSAGE; GENOTYPE; HUMANS; HYBRID CELLS; LINEAR MODELS; MALE; MIDDLE AGED; MITOCHONDRIA; OXYGEN CONSUMPTION; PARKINSON DISEASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 71549164305     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2009.09.025     Document Type: Article

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