Panaxynol protects cortical neurons from ischemia-like injury by up-regulation of HIF-1α expression and inhibition of apoptotic cascade

Chemico-Biological Interactions

Volumn 183, Issue 1, 2010, Pages 165-171

  Yang, Zhi hui ^a   Sun, Ke ^b   Yan, Zhong hong ^a   Suo, Wen hao ^a   Fu, Guo hui ^a   Lu, Yang ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

Bax; Bcl 2; Caspase 3; HIF 1 ; Hypoxia; Panaxynol

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CASPASE 3; HOE 33342; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LACTATE DEHYDROGENASE; PANAXYNOL; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; BRAIN INJURY; BRAIN ISCHEMIA; CELL HYPOXIA; CELL SURVIVAL; CONTROLLED STUDY; DEGENERATIVE DISEASE; DRUG ISOLATION; EMBRYO; ENZYME ACTIVATION; FLOW CYTOMETRY; NERVE CELL; NEUROPROTECTION; NONHUMAN; PANAX NOTOGINSENG; PLANT ROOT; PROTEIN EXPRESSION; RAT; RISK REDUCTION; UPREGULATION;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BRAIN ISCHEMIA; CASPASE 3; CELL HYPOXIA; CELLS, CULTURED; CEREBRAL CORTEX; DIYNES; FATTY ALCOHOLS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; NERVE DEGENERATION; NEURONS; NEUROPROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; UP-REGULATION;

EID: 71349087527     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.09.020     Document Type: Article

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