Nickel induces intracellular calcium mobilization and pathophysiological responses in human cultured airway epithelial cells

Chemico-Biological Interactions

Volumn 183, Issue 1, 2010, Pages 25-33

  Cortijo, Julio ^a,b,c   Milara, Javier ^b   Mata, Manuel ^b,c   Donet, Eva ^c   Gavara, Nuria ^c,d   Peel, Samantha E ^e   Hall, Ian P ^e   Morcillo, E J ^a,c,f  

^a UNIVERSITY OF VALENCIA   (Spain)

^b HOSPITAL GENERAL UNIVERSITARIO DE VALENCIA   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

^d UNIVERSITY OF BARCELONA   (Spain)

^e UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^f HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

Author keywords

Ca2+ sensing receptor; Human airway epithelial cells; Nickel

Indexed keywords

CALCIUM ION; CALCIUM SENSING RECEPTOR; COLLAGEN; CYTOKINE; INOSITOL TRISPHOSPHATE; MESSENGER RNA; NICKEL; PHOSPHOLIPASE C; RYANODINE; SMALL INTERFERING RNA; THAPSIGARGIN;

ARTICLE; BRONCHUS MUCOSA; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CELL PROLIFERATION; CELL STIMULATION; COLLAGEN SYNTHESIS; ENDOTHELIUM CELL; ENZYME INHIBITION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; LUNG DISEASE; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; TOXICOKINETICS;

CALCIUM; CELLS, CULTURED; EPITHELIAL CELLS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1BETA; MICROSCOPY, FLUORESCENCE; NICKEL; RECEPTORS, CALCIUM-SENSING; RESPIRATORY MUCOSA; RNA, SMALL INTERFERING; RYANODINE; THAPSIGARGIN; TUMOR NECROSIS FACTOR-ALPHA; TYPE C PHOSPHOLIPASES;

EID: 71349084521     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.09.011     Document Type: Article

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