메뉴 건너뛰기




Volumn 45, Issue 7, 2009, Pages 497-505

Plerixafor hydrochloride: A novel agent for the mobilization of peripheral blood stem cells

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; GRANULOCYTE COLONY STIMULATING FACTOR; PLACEBO; PLERIXAFOR; STROMAL CELL DERIVED FACTOR 1;

EID: 71249160513     PISSN: 16993993     EISSN: 16994019     Source Type: Journal    
DOI: 10.1358/dot.2009.45.7.1395292     Document Type: Review
Times cited : (22)

References (40)
  • 1
    • 0034097402 scopus 로고    scopus 로고
    • + cell dose in blood cell transplantation for cancer therapy
    • Siena, S., Schiavo, R., Pedrazzoli, P., Carlo-Stella, C. Therapeutic relevance of CD34 cell dose in blood cell transplantation for cancer therapy. J Clin Oncol 2000, 18(6): 1360-1377 (Pubitemid 30159857)
    • (2000) Journal of Clinical Oncology , vol.18 , Issue.6 , pp. 1360-1377
    • Siena, S.1    Schiavo, R.2    Pedrazzoli, P.3    Carlo-Stella, C.4
  • 2
    • 0028874087 scopus 로고
    • Harvesting and enrichment of hematopoietic progenitor cells mobilized into the peripheral blood of normal donors by granulocyte-macrophage colony-stimulating factor (GM-CSF) or G-CSF: Potential role in allogeneic marrow transplantation
    • Lane, T., Law, P., Maruyama, M. et al. Harvesting and enrichment of hematopoietic progenitor cells mobilized into the peripheral blood of normal donors by granulocyte-macrophage colony-stimulating factor (GM-CSF) or G-CSF: potential role in allogeneic marrow transplantation. Blood 1995, 85(1): 275-282
    • (1995) Blood , vol.85 , Issue.1 , pp. 275-282
    • Lane, T.1    Law, P.2    Maruyama, M.3
  • 3
    • 0027413697 scopus 로고
    • Comparative effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy
    • Peters, W., Rosner, G., Ross, M. et al. Comparative effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy. Blood 1993, 81(7): 1709-1719
    • (1993) Blood , vol.81 , Issue.7 , pp. 1709-1719
    • Peters, W.1    Rosner, G.2    Ross, M.3
  • 4
    • 49449091143 scopus 로고    scopus 로고
    • Impact of mobilization and remobilization strategies on achieving sufficient stem cell yields for autologous transplantation
    • Pusic, I., Jiang, S.Y., Landua, S. et al. Impact of mobilization and remobilization strategies on achieving sufficient stem cell yields for autologous transplantation. Biol Blood Marrow Transplant 2008, 14(9): 1045-1056
    • (2008) Biol Blood Marrow Transplant , vol.14 , Issue.9 , pp. 1045-1056
    • Pusic, I.1    Jiang, S.Y.2    Landua, S.3
  • 5
    • 0033560848 scopus 로고    scopus 로고
    • A randomized phase 3 study of peripheral blood progenitor cell mobilization with stem cell factor and filgrastim in high-risk breast cancer patients
    • Shpall, E.J., Wheeler, C.A., Turner, S.A. et al. A randomized phase 3 study of peripheral blood progenitor cell mobilization with stem cell factor and filgrastim in high-risk breast cancer patients. Blood 1999, 93(8): 2491-2501
    • (1999) Blood , vol.93 , Issue.8 , pp. 2491-2501
    • Shpall, E.J.1    Wheeler, C.A.2    Turner, S.A.3
  • 6
    • 6444244697 scopus 로고    scopus 로고
    • Use of thrombopoietin in combination with chemotherapy and granulocyte colony-stimulating factor for peripheral blood progenitor cell mobilization
    • Gajewski, J.L., Rondon, G., Donato, M.L. et al. Use of thrombopoietin in combination with chemotherapy and granulocyte colony-stimulating factor for peripheral blood progenitor cell mobilization. Biol Blood Marrow Transplant 2002, 8(10): 550-556
    • (2002) Biol Blood Marrow Transplant , vol.8 , Issue.10 , pp. 550-556
    • Gajewski, J.L.1    Rondon, G.2    Donato, M.L.3
  • 7
    • 84878706688 scopus 로고    scopus 로고
    • Transplantation of peripheral blood stem cells mobilized by single dose application of pegylated G-CSF in patients with multiple myeloma
    • Abst 3554
    • Steidl, U., Fenk, R., Kondalkci, M. et al. Transplantation of peripheral blood stem cells mobilized by single dose application of pegylated G-CSF in patients with multiple myeloma. Blood [45th Annu Meet Am Soc Hematol (Dec 6-9, San Diego) 2003] 2003, 102(11): Abst 3554.
    • (2003) Blood [45th Annu Meet Am Soc Hematol (Dec 6-9, San Diego) 2003] , vol.102 , Issue.11
    • Steidl, U.1    Fenk, R.2    Kondalkci, M.3
  • 8
    • 33746685587 scopus 로고    scopus 로고
    • Characterization of the molecular pharmacology of AMD3100: A specific antagonist of the G-protein coupled chemokine receptor, CXCR4
    • Fricker, S.P., Anastassov, V., Cox, J. et al. Characterization of the molecular pharmacology of AMD3100: A specific antagonist of the G-protein coupled chemokine receptor, CXCR4. Biochem Pharmacol 2006, 72(5): 588-596
    • (2006) Biochem Pharmacol , vol.72 , Issue.5 , pp. 588-596
    • Fricker, S.P.1    Anastassov, V.2    Cox, J.3
  • 9
    • 0035957911 scopus 로고    scopus 로고
    • Molecular Interactions of Cyclam and Bicyclam Non-peptide Antagonists with the CXCR4 Chemokine Receptor
    • Gerlach, L.O., Skerlj, R.T., Bridger, G.J., Schwartz, T.W. Molecular interactions of cyclam and bicyclam non-peptide antagonists with the CXCR4 chemokine receptor. J Biol Chem 2001, 276(17): 14153-14160 (Pubitemid 37391801)
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.17 , pp. 14153-14160
    • Gerlach, L.O.1    Skerlj, R.T.2    Bridger, G.J.3    Schwartz, T.W.4
  • 10
    • 0033524834 scopus 로고    scopus 로고
    • Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4
    • Peled, A., Petit, I., Kollet, O. et al. Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4. Science 1999, 283(5403): 845-848
    • (1999) Science , vol.283 , Issue.5403 , pp. 845-848
    • Peled, A.1    Petit, I.2    Kollet, O.3
  • 11
    • 0036302147 scopus 로고    scopus 로고
    • G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4
    • Petit, I., Szyper-Kravitz, M., Nagler, A. et al. G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4. Nat Immunol 2002, 3(7): 687-94.
    • (2002) Nat Immunol , vol.3 , Issue.7 , pp. 687-694
    • Petit, I.1    Szyper-Kravitz, M.2    Nagler, A.3
  • 12
    • 0037237648 scopus 로고    scopus 로고
    • Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide
    • Levesque, J.-P., Hendy, J., Takamatsu, Y., Simmons, P.J., Bendall, L.J. Disruption of the CXCR4/CXCL12 chemotactic interaction during hematopoietic stem cell mobilization induced by GCSF or cyclophosphamide. J Clin Invest 2003, 111(2): 187-196
    • (2003) J Clin Invest , vol.111 , Issue.2 , pp. 187-196
    • Levesque, J.-P.1    Hendy, J.2    Takamatsu, Y.3    Simmons, P.J.4    Bendall, L.J.5
  • 13
    • 0036754547 scopus 로고    scopus 로고
    • Current understanding of stem cell mobilization: The roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells
    • DOI 10.1016/S0301-472X(02)00883-4, PII S0301472X02008834
    • Lapidot, T., Petit, I. Current understanding of stem cell mobilization: The roles of chemokines, proteolytic enzymes, adhesion molecules, cytokines, and stromal cells. Exp Hematol 2002, 30(9): 973-981 (Pubitemid 35286613)
    • (2002) Experimental Hematology , vol.30 , Issue.9 , pp. 973-981
    • Lapidot, T.1    Petit, I.2
  • 14
    • 27644517442 scopus 로고    scopus 로고
    • G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow
    • Semerad, C.L., Christopher, M.J., Liu, F. et al. G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow. Blood 2005, 106(9): 3020-3027
    • (2005) Blood , vol.106 , Issue.9 , pp. 3020-3027
    • Semerad, C.L.1    Christopher, M.J.2    Liu, F.3
  • 15
    • 19144361854 scopus 로고    scopus 로고
    • A pharmacokinetic-pharmacodynamic model for the mobilization of CD34+ hematopoietic progenitor cells by AMD3100
    • Lack, N.A., Green, B., Dale, D.C. et al. A pharmacokinetic- pharmacodynamic model for the mobilization of CD34+ hematopoietic progenitor cells by AMD3100. Clin Pharmacol Ther 2005, 77(5): 427-436
    • (2005) Clin Pharmacol Ther , vol.77 , Issue.5 , pp. 427-436
    • Lack, N.A.1    Green, B.2    Dale, D.C.3
  • 17
    • 58149182700 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of plerixafor in patients with non-Hodgkin lymphoma and multiple myeloma
    • Stewart, D.A., Smith, C., MacFarland, R., Calandra, G. Pharmacokinetics and pharmacodynamics of plerixafor in patients with non-Hodgkin lymphoma and multiple myeloma. Biol Blood Marrow Transplant 2009, 15(1): 39-46.
    • (2009) Biol Blood Marrow Transplant , vol.15 , Issue.1 , pp. 39-46
    • Stewart, D.A.1    Smith, C.2    MacFarland, R.3    Calandra, G.4
  • 18
    • 53749085874 scopus 로고    scopus 로고
    • A phase II study of plerixafor (AMD3100) plus G-CSF for autologous hematopoietic progenitor cell mobilization in patients with Hodgkin lymphoma
    • Cashen, A., Lopez, S., Gao, F. et al. A phase II study of plerixafor (AMD3100) plus G-CSF for autologous hematopoietic progenitor cell mobilization in patients with Hodgkin lymphoma. Biol Blood Marrow Transplant 2008, 14(11): 1253-1261
    • (2008) Biol Blood Marrow Transplant , vol.14 , Issue.11 , pp. 1253-1261
    • Cashen, A.1    Lopez, S.2    Gao, F.3
  • 19
    • 0034120373 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers
    • Hendrix, C., Flexner, C., MacFarland, R. et al. Pharmacokinetics and safety of AMD-3100, a novel antagonist of the CXCR-4 chemokine receptor, in human volunteers. Antimicrob Agents Chemother 2000, 44(6): 1667-1673
    • (2000) Antimicrob Agents Chemother , vol.44 , Issue.6 , pp. 1667-1673
    • Hendrix, C.1    Flexner, C.2    MacFarland, R.3
  • 20
    • 4644227515 scopus 로고    scopus 로고
    • Safety, pharmacokinetics, and antiviral activity of AMD3100, a selective CXCR4 receptor inhibitor, in HIV-1 infection
    • Hendrix, C.W., Collier, A.C., Lederman, M.M. et al. Safety, pharmacokinetics, and antiviral activity of AMD3100, a selective CXCR4 receptor inhibitor, in HIV-1 infection. J Acquir Immune Defic Syndr 2004, 37(2): 1253-1262
    • (2004) J Acquir Immune Defic Syndr , vol.37 , Issue.2 , pp. 1253-1262
    • Hendrix, C.W.1    Collier, A.C.2    Lederman, M.M.3
  • 21
    • 0141923918 scopus 로고    scopus 로고
    • Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist
    • Liles, W.C., Broxmeyer, H.E., Rodger, E. et al. Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist. Blood 2003, 102(8): 2728-2730
    • (2003) Blood , vol.102 , Issue.8 , pp. 2728-2730
    • Liles, W.C.1    Broxmeyer, H.E.2    Rodger, E.3
  • 22
    • 20144362394 scopus 로고    scopus 로고
    • Augmented mobilization and collection of CD34+ hematopoietic cells from normal human volunteers stimulated with granulocyte-colony-stimulating factor by single-dose administration of AMD3100, a CXCR4 antagonist
    • Liles, W.C., Rodger, E., Broxmeyer, H.E. et al. Augmented mobilization and collection of CD34+ hematopoietic cells from normal human volunteers stimulated with granulocyte-colony-stimulating factor by single-dose administration of AMD3100, a CXCR4 antagonist. Transfusion 2005, 45(3): 295-300.
    • (2005) Transfusion , vol.45 , Issue.3 , pp. 295-300
    • Liles, W.C.1    Rodger, E.2    Broxmeyer, H.E.3
  • 23
    • 1842509856 scopus 로고    scopus 로고
    • Rapid mobilization of CD34+ cells following administration of the CXCR4 antagonist AMD3100 to patients with multiple myeloma and non-Hodgkin's lymphoma
    • Devine, S.M., Flomenberg, N., Vesole, D.H. et al. Rapid mobilization of CD34+ cells following administration of the CXCR4 antagonist AMD3100 to patients with multiple myeloma and non-Hodgkin's lymphoma. J Clin Oncol 2004, 22(6): 1095-1102
    • (2004) J Clin Oncol , vol.22 , Issue.6 , pp. 1095-1102
    • Devine, S.M.1    Flomenberg, N.2    Vesole, D.H.3
  • 25
    • 34548491600 scopus 로고    scopus 로고
    • + cells and dendritic cells by AMD3100 plus granulocyte-colony-stimulating factor in non-Hodgkin's lymphoma patients
    • DOI 10.1089/scd.2006.0087
    • Gazitt, Y., Freytes, C.O., Akay, C., Badel, K., Calandra, G. Improved mobilization of peripheral blood CD34+ Cells and dendritic cells by AMD3100 plus granulocyte-colony-stimulating factor in non-Hodgkin's lymphoma patients. Stem Cells Devel 2007, 16(4): 657-666 (Pubitemid 47378738)
    • (2007) Stem Cells and Development , vol.16 , Issue.4 , pp. 657-666
    • Gazitt, Y.1    Freytes, C.O.2    Akay, C.3    Badel, K.4    Calandra, G.5
  • 26
    • 58249125135 scopus 로고    scopus 로고
    • Treatment with plerixafor in non-Hodgkin's lymphoma and multiple myeloma patients to increase the number of peripheral blood stem cells when given a mobilizing regimen of G-CSF: Implications for the heavily pretreated patient
    • Stiff, P., Micallef, I., McCarthy, P. et al. Treatment with plerixafor in non-Hodgkin's lymphoma and multiple myeloma patients to increase the number of peripheral blood stem cells when given a mobilizing regimen of G-CSF: Implications for the heavily pretreated patient. Biol Blood Marrow Transplant 2009, 15(2): 249-256
    • (2009) Biol Blood Marrow Transplant , vol.15 , Issue.2 , pp. 249-256
    • Stiff, P.1    Micallef, I.2    McCarthy, P.3
  • 27
    • 71249122949 scopus 로고    scopus 로고
    • Single agent AMD3100 mobilization of peripheral blood progenitor cells for autologous transplantation in patients with multiple myeloma (MM)
    • Abst 3381
    • Flomenberg, N., Comenzo, R., Badel, K., Calandra, G. Single agent AMD3100 mobilization of peripheral blood progenitor cells for autologous transplantation in patients with multiple myeloma (MM). Blood [48th Annu Meet Am Soc Hematol (Dec 9-12, Orlando) 2006] 2006, 108(11): Abst 3381.
    • (2006) Blood [48th Annu Meet Am Soc Hematol (Dec 9-12, Orlando) 2006] , vol.108 , Issue.11
    • Flomenberg, N.1    Comenzo, R.2    Badel, K.3    Calandra, G.4
  • 28
    • 75149188308 scopus 로고    scopus 로고
    • Safety and preliminary efficacy of plerixafor (Mozobil) in combination with chemotherapy and G-CSF: An open-label, multicenter, exploratory trial in patients with multiple myeloma and non-Hodgkin's lymphoma undergoing stem cell mobilization
    • doi:10.1038/bmt.2009.119.
    • Dugan, M.J., Maziarz, R.T., Bensinger, W.I. et al. Safety and preliminary efficacy of plerixafor (Mozobil) in combination with chemotherapy and G-CSF: an open-label, multicenter, exploratory trial in patients with multiple myeloma and non-Hodgkin's lymphoma undergoing stem cell mobilization Bone Marrow Transplant 2009, doi:10.1038/bmt.2009.119.
    • (2009) Bone Marrow Transplant
    • Dugan, M.J.1    Maziarz, R.T.2    Bensinger, W.I.3
  • 29
    • 51649128399 scopus 로고    scopus 로고
    • Rapid mobilization of functional donor hematopoietic cells without G-CSF using AMD3100, an antagonist of the CXCR4/SDF-1 interaction
    • Devine, S.M., Vij, R., Rettig, M. et al. Rapid mobilization of functional donor hematopoietic cells without G-CSF using AMD3100, an antagonist of the CXCR4/SDF-1 interaction. Blood 2008, 112(4): 990-998
    • (2008) Blood , vol.112 , Issue.4 , pp. 990-998
    • Devine, S.M.1    Vij, R.2    Rettig, M.3
  • 31
    • 33947245648 scopus 로고    scopus 로고
    • Human Progenitor Cells Rapidly Mobilized by AMD3100 Repopulate NOD/SCID Mice with Increased Frequency in Comparison to Cells from the Same Donor Mobilized by Granulocyte Colony Stimulating Factor
    • DOI 10.1016/j.bbmt.2006.12.445, PII S1083879106013073
    • Hess, D.A., Bonde, J., Craft, T.C. et al. Human progenitor cells rapidly mobilized by AMD3100 repopulate NOD/SCID mice with increased frequency in comparison to cells from the same donor mobilized by granulocyte colony stimulating factor. Biol Blood Marrow Transplant 2007, 13(4): 398-411. (Pubitemid 46421895)
    • (2007) Biology of Blood and Marrow Transplantation , vol.13 , Issue.4 , pp. 398-411
    • Hess, D.A.1    Bonde, J.2    Craft, T.C.3    Wirthlin, L.4    Hohm, S.5    Lahey, R.6    Todt, L.M.7    Dipersio, J.F.8    Devine, S.M.9    Nolta, J.A.10
  • 32
    • 33646398840 scopus 로고    scopus 로고
    • AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates
    • Larochelle, A., Krause, A., Metzger, M. et al. AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates. Blood 2006, 107(9): 3772-3778
    • (2006) Blood , vol.107 , Issue.9 , pp. 3772-3778
    • Larochelle, A.1    Krause, A.2    Metzger, M.3
  • 34
    • 28444443372 scopus 로고    scopus 로고
    • Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model
    • DOI 10.1182/blood-2005-05-1937
    • Burroughs, L., Mielcarek, M., Little, M.-T. et al. Durable engraftment of AMD3100-mobilized autologous and allogeneic peripheral-blood mononuclear cells in a canine transplantation model. Blood 2005, 106(12): 4002-4008 (Pubitemid 41739045)
    • (2005) Blood , vol.106 , Issue.12 , pp. 4002-4008
    • Burroughs, L.1    Mielcarek, M.2    Little, M.-T.3    Bridger, G.4    MacFarland, R.5    Fricker, S.6    Labrecque, J.7    Sandmaier, B.M.8    Storb, R.9
  • 35
    • 53749107496 scopus 로고    scopus 로고
    • A phase III, multicenter, randomized, double-blind, placebo controlled, comparative trial of AMD3100 (Plerixafor)+G-CSF vs. placebo+G-CSF in non-Hodgkin's lymphoma (NHL) patients for autologous hematopoietic stem cell (aHSC) transplantation
    • Abst 601
    • DiPersio, J.F., Micallef, I., Stiff, P.J. et al. A phase III, multicenter, randomized, double-blind, placebo controlled, comparative trial of AMD3100 (Plerixafor)+G-CSF vs. placebo+G-CSF in non-Hodgkin's lymphoma (NHL) patients for autologous hematopoietic stem cell (aHSC) transplantation. Blood [49th Annu Meet Am Soc Hematol (Dec 8-11, Atlanta) 2007] 2007, 110(11): Abst 601.
    • (2007) Blood [49th Annu Meet Am Soc Hematol (Dec 8-11, Atlanta) 2007] , vol.110 , Issue.11
    • Dipersio, J.F.1    Micallef, I.2    Stiff, P.J.3
  • 36
    • 67651089936 scopus 로고    scopus 로고
    • Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma
    • DiPersio, J.F., Stadtmauer, E.A., Nademanee, A. et al. Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma. Blood 2009, 113(23): 5720-5726
    • (2009) Blood , vol.113 , Issue.23 , pp. 5720-5726
    • Dipersio, J.F.1    Stadtmauer, E.A.2    Nademanee, A.3
  • 37
    • 40249093217 scopus 로고    scopus 로고
    • AMD3100 plus G-CSF can successfully mobilize CD34+ cells from non-Hodgkin's lymphoma, Hodgkin's disease and multiple myeloma patients previously failing mobilization with chemotherapy and/or cytokine treatment: Compassionate use data
    • Calandra, G., McCarty, J., McGuirk, J. et al. AMD3100 plus G-CSF can successfully mobilize CD34+ cells from non-Hodgkin's lymphoma, Hodgkin's disease and multiple myeloma patients previously failing mobilization with chemotherapy and/or cytokine treatment: Compassionate use data. Bone Marrow Transplantation 2007, 41(4): 331-338
    • (2007) Bone Marrow Transplantation , vol.41 , Issue.4 , pp. 331-338
    • Calandra, G.1    McCarty, J.2    McGuirk, J.3
  • 38
    • 48249148032 scopus 로고    scopus 로고
    • Successful stem cell mobilization rescue by AMD3100 (Plerixafor)+G-CSF for patients who failed primary mobilization: Results from the phase III (3101-NHL) study
    • Abst 602.
    • Micallef, I., Stiff, P.J., DiPersio, J.F. et al. Successful stem cell mobilization rescue by AMD3100 (Plerixafor)+G-CSF for patients who failed primary mobilization: results from the phase III (3101-NHL) study. Blood [49th Annu Meet Am Soc Hematol (Dec 8-11, Atlanta) 2007] 2007, 110(11): Abst 602.
    • (2007) Blood [49th Annu Meet Am Soc Hematol (Dec 8-11, Atlanta) 2007] , vol.110 , Issue.11
    • Micallef, I.1    Stiff, P.J.2    Dipersio, J.F.3
  • 39
    • 67650410440 scopus 로고    scopus 로고
    • Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100
    • Nervi, B., Ramirez, P., Rettig, M.P. et al. Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100. Blood 2009, 113(24): 6206-6214
    • (2009) Blood , vol.113 , Issue.24 , pp. 6206-6214
    • Nervi, B.1    Ramirez, P.2    Rettig, M.P.3
  • 40
    • 68249092200 scopus 로고    scopus 로고
    • Mobilization and chemosensitization of AML with the CXCR4 antagonist plerixafor (AMD3100): A phase I/II study of AMD3100+MEC in patients with relapsed or refractory disease
    • Abst 1944
    • Uy, G.L., Rettig, M.P., McFarland, K.M. et al. Mobilization and chemosensitization of AML with the CXCR4 antagonist plerixafor (AMD3100): A phase I/II study of AMD3100+MEC in patients with relapsed or refractory disease. Blood [50th Annu Meet Am Soc Hematol (Dec 6-9, San Francisco) 2008] 2008, 112(11): Abst 1944.
    • (2008) Blood [50th Annu Meet Am Soc Hematol (Dec 6-9, San Francisco) 2008] , vol.112 , Issue.11
    • Uy, G.L.1    Rettig, M.P.2    McFarland, K.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.