-
2
-
-
24344439264
-
Transporters and drug therapy: implications for drug disposition and disease
-
Ho R.H., and Kim R.B. Transporters and drug therapy: implications for drug disposition and disease. Clin. Pharmacol. Ther. 78 (2005) 260-277
-
(2005)
Clin. Pharmacol. Ther.
, vol.78
, pp. 260-277
-
-
Ho, R.H.1
Kim, R.B.2
-
4
-
-
14644409841
-
The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk
-
Jonker J.W., Merino G., Musters S., van Herwaarden A.E., Bolscher E., Wagenaar E., Mesman E., Dale T.C., and Schinkel A.H. The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk. Nat. Med. 11 (2005) 127-129
-
(2005)
Nat. Med.
, vol.11
, pp. 127-129
-
-
Jonker, J.W.1
Merino, G.2
Musters, S.3
van Herwaarden, A.E.4
Bolscher, E.5
Wagenaar, E.6
Mesman, E.7
Dale, T.C.8
Schinkel, A.H.9
-
5
-
-
33644682781
-
Breast cancer resistance protein (Bcrp/abcg2) is a major determinant of sulfasalazine absorption and elimination in the mouse
-
Zaher H., Khan A.A., Palandra J., Brayman T.G., Yu L., and Ware J.A. Breast cancer resistance protein (Bcrp/abcg2) is a major determinant of sulfasalazine absorption and elimination in the mouse. Mol. Pharm. 3 (2006) 55-61
-
(2006)
Mol. Pharm.
, vol.3
, pp. 55-61
-
-
Zaher, H.1
Khan, A.A.2
Palandra, J.3
Brayman, T.G.4
Yu, L.5
Ware, J.A.6
-
6
-
-
0037169551
-
Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor
-
Kast H.R., Goodwin B., Tarr P.T., Jones S.A., Anisfeld A.M., Stoltz C.M., Tontonoz P., Kliewer S., Willson T.M., and Edwards P.A. Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor. J. Biol. Chem. 277 (2002) 2908-2915
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 2908-2915
-
-
Kast, H.R.1
Goodwin, B.2
Tarr, P.T.3
Jones, S.A.4
Anisfeld, A.M.5
Stoltz, C.M.6
Tontonoz, P.7
Kliewer, S.8
Willson, T.M.9
Edwards, P.A.10
-
7
-
-
0032754284
-
The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin
-
Greiner B., Eichelbaum M., Fritz P., Kreichgauer H.P., von Richter O., Zundler J., and Kroemer H.K. The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin. J. Clin. Invest. 104 (1999) 147-153
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 147-153
-
-
Greiner, B.1
Eichelbaum, M.2
Fritz, P.3
Kreichgauer, H.P.4
von Richter, O.5
Zundler, J.6
Kroemer, H.K.7
-
8
-
-
0035805536
-
Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin
-
Geick A., Eichelbaum M., and Burk O. Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin. J. Biol. Chem. 276 (2001) 14581-14587
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 14581-14587
-
-
Geick, A.1
Eichelbaum, M.2
Burk, O.3
-
9
-
-
26844549175
-
A role for constitutive androstane receptor in the regulation of human intestinal MDR1 expression
-
Burk O., Arnold K.A., Geick A., Tegude H., and Eichelbaum M. A role for constitutive androstane receptor in the regulation of human intestinal MDR1 expression. Biol. Chem. 386 (2005) 503-513
-
(2005)
Biol. Chem.
, vol.386
, pp. 503-513
-
-
Burk, O.1
Arnold, K.A.2
Geick, A.3
Tegude, H.4
Eichelbaum, M.5
-
10
-
-
33747640562
-
Peroxisome proliferator-activated receptor gamma-regulated ABCG2 expression confers cytoprotection to human dendritic cells
-
Szatmari I., Vámosi G., Brazda P., Balint B.L., Benko S., Széles L., Jeney V., Özvegy-Laczka C., Szántó A., Barta E., Balla J., Sarkadi B., and Nagy1 L. Peroxisome proliferator-activated receptor gamma-regulated ABCG2 expression confers cytoprotection to human dendritic cells. J. Biol. Chem. 281 (2006) 23812-23823
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 23812-23823
-
-
Szatmari, I.1
Vámosi, G.2
Brazda, P.3
Balint, B.L.4
Benko, S.5
Széles, L.6
Jeney, V.7
Özvegy-Laczka, C.8
Szántó, A.9
Barta, E.10
Balla, J.11
Sarkadi, B.12
Nagy1, L.13
-
11
-
-
0034710965
-
Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha
-
Venkateswaran A., Laffitte B.A., Joseph S.B., Mak P.A., Wilpitz D.C., Edwards P.A., and Tontonoz P. Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 12097-12102
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 12097-12102
-
-
Venkateswaran, A.1
Laffitte, B.A.2
Joseph, S.B.3
Mak, P.A.4
Wilpitz, D.C.5
Edwards, P.A.6
Tontonoz, P.7
-
12
-
-
0034640288
-
Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols
-
Venkateswaran A., Repa J.J., Lobaccaro J.M., Bronson A., Mangelsdorf D.J., and Edwards P.A. Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols. J. Biol. Chem. 275 (2000) 14700-14707
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 14700-14707
-
-
Venkateswaran, A.1
Repa, J.J.2
Lobaccaro, J.M.3
Bronson, A.4
Mangelsdorf, D.J.5
Edwards, P.A.6
-
13
-
-
0034623288
-
Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor
-
Costet P., Luo Y., Wang N., and Tall A.R. Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor. J. Biol. Chem. 275 (2000) 28240-28245
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28240-28245
-
-
Costet, P.1
Luo, Y.2
Wang, N.3
Tall, A.R.4
-
14
-
-
0037166261
-
Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors α and β
-
Repa J.J., Berge K.E., Pomajzl C., Richardson J.A., Hobbs H., and Mangelsdorf D.J. Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors α and β. J. Biol. Chem. 277 (2002) 18793-18800
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18793-18800
-
-
Repa, J.J.1
Berge, K.E.2
Pomajzl, C.3
Richardson, J.A.4
Hobbs, H.5
Mangelsdorf, D.J.6
-
15
-
-
0037450981
-
Liver X receptors and the control of cholesterol homeostasis: potential therapeutic targets for the treatment of atherosclerosis
-
Millatt L.J., Bocher V., Fruchart J.C., and Staels B. Liver X receptors and the control of cholesterol homeostasis: potential therapeutic targets for the treatment of atherosclerosis. Biochim. Biophys. Acta 1631 (2003) 107-118
-
(2003)
Biochim. Biophys. Acta
, vol.1631
, pp. 107-118
-
-
Millatt, L.J.1
Bocher, V.2
Fruchart, J.C.3
Staels, B.4
-
16
-
-
0035895202
-
-
Laffitte B.A., Repa J.J., Joseph S.B., Wilpitz D.C., Kast H.R., Mangelsdorf D.J., and Tontonoz P. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 507-512
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 507-512
-
-
Laffitte, B.A.1
Repa, J.J.2
Joseph, S.B.3
Wilpitz, D.C.4
Kast, H.R.5
Mangelsdorf, D.J.6
Tontonoz, P.7
-
17
-
-
41749102617
-
Association between risk of myopathy and cholesterol-lowering effect: a comparison of all statins
-
Kobayashi M., Chisaki I., Narumi K., Hidaka K., Kagawa T., Itagaki S., Hirano T., and Iseki K. Association between risk of myopathy and cholesterol-lowering effect: a comparison of all statins. Life Sci. 82 (2008) 969-975
-
(2008)
Life Sci.
, vol.82
, pp. 969-975
-
-
Kobayashi, M.1
Chisaki, I.2
Narumi, K.3
Hidaka, K.4
Kagawa, T.5
Itagaki, S.6
Hirano, T.7
Iseki, K.8
-
18
-
-
53549133372
-
Bicarbonate supplementation as a preventive way in statins-induced muscle damage
-
Kobayashi M., Kagawa T., Narumi K., Itagaki S., Hirano T., and Iseki K. Bicarbonate supplementation as a preventive way in statins-induced muscle damage. J. Pharm. Pharm. Sci. 11 (2008) 1-8
-
(2008)
J. Pharm. Pharm. Sci.
, vol.11
, pp. 1-8
-
-
Kobayashi, M.1
Kagawa, T.2
Narumi, K.3
Itagaki, S.4
Hirano, T.5
Iseki, K.6
-
19
-
-
0028334949
-
A one-hour minipreparation technique for extraction of DNA-binding proteins from animal tissues
-
Deryckere F., and Gannon F. A one-hour minipreparation technique for extraction of DNA-binding proteins from animal tissues. BioTechniques 16 (1994) 405
-
(1994)
BioTechniques
, vol.16
, pp. 405
-
-
Deryckere, F.1
Gannon, F.2
-
21
-
-
33745000275
-
Inhibitory effects of statins on human monocarboxylate transporter 4
-
Kobayashi M., Otsuka Y., Itagaki S., Hirano T., and Iseki K. Inhibitory effects of statins on human monocarboxylate transporter 4. Int. J. Pharm. 317 (2006) 19-25
-
(2006)
Int. J. Pharm.
, vol.317
, pp. 19-25
-
-
Kobayashi, M.1
Otsuka, Y.2
Itagaki, S.3
Hirano, T.4
Iseki, K.5
-
22
-
-
33645104770
-
Characterization of transport protein expression in multidrug resistance-associated protein (Mrp) 2-deficient rats
-
Johnson B.M., Zhang P., Schuetz J.D., and Brouwer K.L. Characterization of transport protein expression in multidrug resistance-associated protein (Mrp) 2-deficient rats. Drug Metab. Dispos. 34 (2006) 556-562
-
(2006)
Drug Metab. Dispos.
, vol.34
, pp. 556-562
-
-
Johnson, B.M.1
Zhang, P.2
Schuetz, J.D.3
Brouwer, K.L.4
-
23
-
-
24944534020
-
Transport mechanism for L-lactic acid in human myocytes using human prototypic embryonal rhabdomyosarcoma cell line (RD cells)
-
Kobayashi M., Fujita I., Itagaki S., Hirano T., and Iseki K. Transport mechanism for L-lactic acid in human myocytes using human prototypic embryonal rhabdomyosarcoma cell line (RD cells). Biol. Pharm. Bull. 28 (2005) 1197-1201
-
(2005)
Biol. Pharm. Bull.
, vol.28
, pp. 1197-1201
-
-
Kobayashi, M.1
Fujita, I.2
Itagaki, S.3
Hirano, T.4
Iseki, K.5
-
24
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
-
Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65 (1983) 55-63
-
(1983)
J. Immunol. Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
25
-
-
34548190628
-
SREBP-1-independent regulation of lipogenic gene expression in adipocytes
-
Sekiya M., Yahagi N., Matsuzaka T., Takeuchi Y., Nakagawa Y., Takahashi H., Okazaki H., Iizuka Y., Ohashi K., Gotoda T., Ishibashi S., Nagai R., Yamazaki T., Kadowaki T., Yamada N., Osuga J., and Shimano H. SREBP-1-independent regulation of lipogenic gene expression in adipocytes. J. Lipid Res. 48 (2007) 1581-1591
-
(2007)
J. Lipid Res.
, vol.48
, pp. 1581-1591
-
-
Sekiya, M.1
Yahagi, N.2
Matsuzaka, T.3
Takeuchi, Y.4
Nakagawa, Y.5
Takahashi, H.6
Okazaki, H.7
Iizuka, Y.8
Ohashi, K.9
Gotoda, T.10
Ishibashi, S.11
Nagai, R.12
Yamazaki, T.13
Kadowaki, T.14
Yamada, N.15
Osuga, J.16
Shimano, H.17
-
26
-
-
0029035278
-
LXR, a nuclear receptor that defines a distinct retinoid response pathway
-
Willy P.J., Umesono K., Ong E.S., Evans R.M., Heyman R.A., and Mangelsdorf D.J. LXR, a nuclear receptor that defines a distinct retinoid response pathway. Gene Dev. 9 (1995) 1033-1045
-
(1995)
Gene Dev.
, vol.9
, pp. 1033-1045
-
-
Willy, P.J.1
Umesono, K.2
Ong, E.S.3
Evans, R.M.4
Heyman, R.A.5
Mangelsdorf, D.J.6
-
27
-
-
0029931972
-
The orphan nuclear hormone receptor LXR alpha interacts with the peroxisome proliferator-activated receptor and inhibits peroxisome proliferator signaling
-
Miyata K.S., McCaw S.E., Patel H.V., Rachubinski R.A., and Capone J.P. The orphan nuclear hormone receptor LXR alpha interacts with the peroxisome proliferator-activated receptor and inhibits peroxisome proliferator signaling. J. Biol. Chem. 271 (1996) 9189-9192
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9189-9192
-
-
Miyata, K.S.1
McCaw, S.E.2
Patel, H.V.3
Rachubinski, R.A.4
Capone, J.P.5
-
28
-
-
0028059845
-
NER, a new member of the gene family encoding the human steroid hormone nuclear receptor
-
Shinar D.M., Endo N., Rutledge S.J., Vogel R., Rodan G.A., and Schmidt A. NER, a new member of the gene family encoding the human steroid hormone nuclear receptor. Gene 147 (1994) 273-276
-
(1994)
Gene
, vol.147
, pp. 273-276
-
-
Shinar, D.M.1
Endo, N.2
Rutledge, S.J.3
Vogel, R.4
Rodan, G.A.5
Schmidt, A.6
-
29
-
-
0029805887
-
An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha
-
Janowski B.A., Willy P.J., Devi T.R., Falck J.R., and Mangelsdorf D.J. An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha. Nature 383 (1996) 728-731
-
(1996)
Nature
, vol.383
, pp. 728-731
-
-
Janowski, B.A.1
Willy, P.J.2
Devi, T.R.3
Falck, J.R.4
Mangelsdorf, D.J.5
-
30
-
-
14444285707
-
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway
-
Lehmann J.M., Kliewer S.A., Moore L.B., Smith-Oliver T.A., Oliver B.B., Su J.-L., Sundseth S.S., Winegar D.A., Blanchard D.E., Spencer T.A., and Wilson T.M. Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway. J. Biol. Chem. 272 (1997) 3137-3140
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3137-3140
-
-
Lehmann, J.M.1
Kliewer, S.A.2
Moore, L.B.3
Smith-Oliver, T.A.4
Oliver, B.B.5
Su, J.-L.6
Sundseth, S.S.7
Winegar, D.A.8
Blanchard, D.E.9
Spencer, T.A.10
Wilson, T.M.11
-
31
-
-
0036851863
-
The liver X receptor gene team: potential new players in atherosclerosis
-
Repa J.J., and Mangelsdorf D.J. The liver X receptor gene team: potential new players in atherosclerosis. Nat. Med. 8 (2002) 1243-1248
-
(2002)
Nat. Med.
, vol.8
, pp. 1243-1248
-
-
Repa, J.J.1
Mangelsdorf, D.J.2
-
32
-
-
0030814774
-
The canalicular multispecific organic anion transporter and conjugated hyperbilirubinemia in rat and man
-
Paulusma C.C., and Oude Elferink R.P. The canalicular multispecific organic anion transporter and conjugated hyperbilirubinemia in rat and man. J. Mol. Med. 75 (1997) 420-428
-
(1997)
J. Mol. Med.
, vol.75
, pp. 420-428
-
-
Paulusma, C.C.1
Oude Elferink, R.P.2
-
33
-
-
0029981430
-
Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene
-
Paulusma C.C., Bosma P.J., Zaman G.J., Bakker C.T., Otter M., Scheffer G.L., Scheper R.J., Borst P., and Oude Elferink R.P. Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene. Science 271 (1996) 1126-1128
-
(1996)
Science
, vol.271
, pp. 1126-1128
-
-
Paulusma, C.C.1
Bosma, P.J.2
Zaman, G.J.3
Bakker, C.T.4
Otter, M.5
Scheffer, G.L.6
Scheper, R.J.7
Borst, P.8
Oude Elferink, R.P.9
-
34
-
-
0040761368
-
cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats
-
Büchler M., König J., Brom M., Kartenbeck J., Spring H., Horie T., and Keppler D. cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats. J. Biol. Chem 271 (1996) 15091-15098
-
(1996)
J. Biol. Chem
, vol.271
, pp. 15091-15098
-
-
Büchler, M.1
König, J.2
Brom, M.3
Kartenbeck, J.4
Spring, H.5
Horie, T.6
Keppler, D.7
-
35
-
-
0032781499
-
Enhanced transport of anticancer agents and leukotriene C4 by the human canalicular multispecific organic anion transporter (cMOAT/MRP2)
-
Kawabe T., Chen Z.S., Wada M., Uchiumi T., Ono M., Akiyama S., and Kuwano M. Enhanced transport of anticancer agents and leukotriene C4 by the human canalicular multispecific organic anion transporter (cMOAT/MRP2). FEBS Lett. 456 (1999) 327-331
-
(1999)
FEBS Lett.
, vol.456
, pp. 327-331
-
-
Kawabe, T.1
Chen, Z.S.2
Wada, M.3
Uchiumi, T.4
Ono, M.5
Akiyama, S.6
Kuwano, M.7
-
36
-
-
0035977844
-
Up-regulation of transporters of the MRP family by drugs and toxins
-
Schrenk D., Baus P.R., Ermel N., Klein C., Vorderstemann B., and Kauffmann H.M. Up-regulation of transporters of the MRP family by drugs and toxins. Toxicol. Lett. 120 (2001) 51-57
-
(2001)
Toxicol. Lett.
, vol.120
, pp. 51-57
-
-
Schrenk, D.1
Baus, P.R.2
Ermel, N.3
Klein, C.4
Vorderstemann, B.5
Kauffmann, H.M.6
-
37
-
-
0001308329
-
Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA
-
Evers R., Kool M., van Deemter L., Janssen H., Calafat J., Oomen L.C., Paulusma C.C., Oude Elferink R.P., Baas F., Schinkel A.H., and Borst P. Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA. J. Clin. Invest. 101 (1998) 1310-1319
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1310-1319
-
-
Evers, R.1
Kool, M.2
van Deemter, L.3
Janssen, H.4
Calafat, J.5
Oomen, L.C.6
Paulusma, C.C.7
Oude Elferink, R.P.8
Baas, F.9
Schinkel, A.H.10
Borst, P.11
-
38
-
-
20444432732
-
Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux
-
Argmann C.A., Edwards J.Y., Sawyez C.G., O'Neil C.H., Hegele R.A., Pickering J.G., and Huff M.W. Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux. J. Biol. Chem. 280 (2005) 22212-22221
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 22212-22221
-
-
Argmann, C.A.1
Edwards, J.Y.2
Sawyez, C.G.3
O'Neil, C.H.4
Hegele, R.A.5
Pickering, J.G.6
Huff, M.W.7
-
39
-
-
17744376173
-
A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis
-
Chawla A., Boisvert W.A., Lee C.H., Laffitte B.A., Barak Y., Joseph S.B., Liao D., Nagy L., Edwards P.A., Curtiss L.K., Evans R.M., and Tontonoz P. A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis. Mol. Cell. 7 (2001) 161-171
-
(2001)
Mol. Cell.
, vol.7
, pp. 161-171
-
-
Chawla, A.1
Boisvert, W.A.2
Lee, C.H.3
Laffitte, B.A.4
Barak, Y.5
Joseph, S.B.6
Liao, D.7
Nagy, L.8
Edwards, P.A.9
Curtiss, L.K.10
Evans, R.M.11
Tontonoz, P.12
|