Overproduction of phosphoprotein enriched in diabetes (PED) induces mesangial expansion and upregulates protein kinase C-β activity and TGF-β1 expression

Diabetologia

Volumn 52, Issue 12, 2009, Pages 2642-2652

  Oriente, F ^a   Iovino, S ^a   Cassese, A ^a   Romano, C ^a   Miele, C ^a   Troncone, G ^a   Balletta, M ^a   Perfetti, A ^a   Santulli, G ^a   Iaccarino, G ^a   Valentino, R ^a   Beguinot, F ^a   Formisano, P ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Diabetic nephropathy; PEA 15; PED; PKC; TGF 1

Indexed keywords

CREATININE; FIBRONECTIN; PHOSPHOLIPASE D; PHOSPHOPROTEIN; PHOSPHOPROTEIN ENRICHED IN DIABETES; PROTEIN KINASE C BETA; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETIC NEPHROPATHY; ENZYME ACTIVITY; ENZYME INHIBITION; EXTRACELLULAR MATRIX; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; KIDNEY FUNCTION; KIDNEY HYPERTROPHY; MESANGIUM; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PED GENE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; TGF BETA1 GENE; TRANSGENIC MOUSE; UPREGULATION;

ACTINS; ANIMALS; ASTROCYTES; BLOOD PRESSURE; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; DNA PRIMERS; FATTY ACIDS, NONESTERIFIED; FIBRONECTINS; GENE EXPRESSION REGULATION; HEART RATE; HUMANS; INSULIN; KIDNEY; KIDNEY FAILURE, CHRONIC; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PHENOTYPE; PHOSPHOPROTEINS; PROTEIN KINASE C; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 70949083239     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-009-1528-z     Document Type: Article

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