Glial cell line-derived neurotrophic factor protects against ischemia- induced injury in the cerebral cortex

Journal of Neuroscience

Volumn 17, Issue 11, 1997, Pages 4341-4348

  Wang, Yun ^a   Lin Shinn Zong, ^a   Chiou, Ai Lin ^a   Williams, Lawrence R ^b   Hoffer, Barry J ^c,d  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b AMGEN INC   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

cerebral ischemia; GDNF; MCA ligation; neuroprotection; nitric oxide; TGF superfamily

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NITRIC OXIDE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN PROTECTION; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOSE RESPONSE; DRUG MECHANISM; GLIA CELL; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE DEGENERATION; NEUROTROPISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; RAT; SPINAL CORD MOTONEURON;

EID: 0030916683     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-11-04341.1997     Document Type: Article

References (23)

1. Basile DP, Rovak JM, Martin DR, Hammerman MR (1996) Increased transforming growth factor-beta 1 expression in regenerating rat renal tubules following ischemic injury. Am J Physiol Renal 39:F500-F509.
2. Beck KD, Valverde J, Alexi T, Poulsen K, Moffat B, Vandlen RA, Rosenthal A, Hefti F (1995) Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain. Nature 373:339-341.
3. Benveniste H, Jorgensen MB, Diemer NH, Hansen AJ (1988) Calcium accumulation by glutamate receptor activation is involved in hippocampal cell damage after ischemia. Acta Neurol Scand 78:529-536.
4. Bickler P (1996) Anoxia-tolerant CA1 neurons from rat hippocampus: anoxia-evoked calcium changes and NMDA receptor inactivation. Soc Neurosci Abstr 22:3.
5. Bowenkamp KE, Hoffman AF, Gerhardt GA, Henry MA, Biddle PT, Hoffer BJ, Granholm AE (1995) Glial cell line-derived neurotrophic factor supports survival of injured midbrain dopaminergic neurons. J Comp Neurol 355:479-489.
6. Brown RD, Whisnant JP, Sicks JD, O'Fallon WM, Wiebers DO (1996) Stroke incidence, prevalence, and survival: secular trends in Rochester, Minnesota, through 1989. Stroke 27:373-380.
7. Caldwell M, O'Neill M, Earley B, Leonard B (1994) NG-Nitro-L-arginine protects against ischaemia-induced increases in nitric oxide and hippocampal neuro-degeneration in the gerbil. Eur J Pharmacol 260:191-200.
8. Chen ST, Hsu CY, Hogan EL, Maricq H, Balentine JD (1986) A model of focal ischemic stroke in the rat: reproducible extensive cortical infarction. Stroke 17:738-743.
9. Dalkara T, Ayata C, Demirci M, Erdemli G, Onur R (1996) Effects of cerebral ischemia on N-methyl-D-aspartate and dihydropyridine-sensitive calcium currents: an electrophysiological study in the rat hippocampus in situ. Stroke 27:127-133.
10. Du C, Hu R, Csernansky CA, Hsu CY, Choi DW (1996) Very delayed infarction after mild focal cerebral ischemia: a role for apoptosis? J Cereb Blood Flow Metab 16:195-201.
11. Earley B, Canney M, Clune B, Caldwell M, Leonard BE, Junien JL (1996) The effects of MK-801, ifenprodil, JO 1784, JO 1994 and JO 1997 on PK 11195 receptor binding, nitric oxide synthase (NO synthase) activity and infarct volume in a mouse model of focal cerebral ischaemia. Neurochem Int 28:509-521.
12. Faraci FM, Breese KR (1993) Nitric oxide mediates vasodilatation in response to activation of N-methyl-D-aspartate receptors in brain. Circ Res 72:476-480.
13. Feelisch M (1991) The biochemical pathways of nitric oxide formation from nitrovasodilators: appropriate choice of exogenous NO donors and aspects of preparation and handling of aqueous NO solutions. J Cardiovasc Pharmacol 17[Suppl 3]:S25-S33.
14. Gash DM, Zhang ZM, Ovadia A, Cass WA, Yi A, Simmerman L, Russell D, Martin D, Lapchak PA, Collins F, Hoffer BJ, Gerhardt GA (1996) Functional recovery in parkinsonian monkeys treated with GDNF. Nature 380:252-255.
15. Gerhardt GA, Oke AF, Nagy G, Moghaddam B, Adams RN (1984) Nafion-coated electrodes with high selectivity for CNS electrochemistry. Brain Res 290:390-395.
16. Hajimohammadreza I, Probert AW, Coughenour LL, Borosky SA, Marcoux FW, Boxer PA, Wang KK (1995) A specific inhibitor of calcium/calmodulin-dependent protein kinase-II provides neuroprotection against NMDA- and hypoxia/hypoglycemia-induced cell death. J Neurosci 15:4093-4101.
17. Olson L, Bjorklund H, Hoffer BJ (1984) Camera bulbi anterior: new vistas on a classical locus for neural tissue transplantation. In: Neuronal transplants, development and function (Sladek J, Gash D, eds), pp 373-406. New York: Plenum.
18. Perrella MA, Hsieh CM, Lee WS, Shieh S, Tsai JC, Patterson C, Lowenstein CJ, Long NC, Haber E, Shore S, Lee ME (1996) Arrest of endotoxin-induced hypotension by transforming growth factor beta 1. Proc Natl Acad Sci USA 93:2054-2059.
19. Trok K, Hoffer B, Olson L (1996) Glial cell line-derived neurotrophic factor enhances survival and growth of prenatal and postnatal spinal cord transplants. Neuroscience 71:231-241.
20. Vornov JJ (1995) Toxic NMDA-receptor activation occurs during recovery in a tissue culture model of ischemia. J Neurochem 65:1681-1691.
21. Wahlestedt C, Golanov E, Yamamoto S, Yee F, Ericson H, Yoo H, Inturrisi CE, Reis DJ (1993) Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicitv and reduce focal ischaemic infarctions. Nature 363:260-263.
22. Yoshida T, Limmroth V, Irikura K, Moskowitz MA (1994) The NOS inhibitor, 7-nitroindazole, decreases focal infarct volume but not the response to topical acetylcholine in pial vessels. J Cereb Blood Flow Metab 14:924-929.
23. Zhang ZG, Reif D, MacDonald J, Tang WX, Kamp DK, Gentile RJ, Shakespeare WC, Murray RJ, Chopp M (1996) ARL 17477, a potent and selective neuronal NOS inhibitor decreases infarct volume after transient middle cerebral artery occlusion in rats. J Cereb Blood Flow Metab 16:599-604.