Adenovirus VAI RNA antagonizes the RNA-editing activity of the ADAR adenosine deaminase

Virology

Volumn 245, Issue 2, 1998, Pages 188-196

  Lei, Ming ^a   Liu, Yong ^a   Samuel, Charles E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS RNA;

ARTICLE; CELL STRAIN COS1; GENE EXPRESSION REGULATION; GENE INDUCTION; NONHUMAN; PRIORITY JOURNAL; RNA EDITING; RNA SEQUENCE; VIRUS EXPRESSION; VIRUS TRANSCRIPTION;

ADENOVIRIDAE; RNA VIRUSES;

EID: 0032486289     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1998.9162     Document Type: Article

References (60)

1. Bass B. L. RNA editing and hypermutation by adenosine deamination. Trends Biochem. Sci. 22:1997;157-162.
2. Bevilacqua P. C., George C. X., Samuel C. E., Cech T. R. Binding of the protein kinase PKR to RNAs with secondary structure defects: Role of the tandem A-G mismatch and noncontiguous helixes. Biochemistry. 37:1998;6303-6316.
3. Burns C. M., Chu H., Rueter S. M., Hutchinson L. K., Canton H., Sanders-Bush E., Emeson R. B. Regulation of serotonin-2C receptor G-protein coupling by RNA editing. Nature. 387:1997;303-308.
4. Cattaneo R. Biased (A → I) hypermutation of animal RNA virus genomes. Curr. Opin. Genet. Dev. 4:1994;895-900.
5. Cattaneo R., Schmid A., Eschle D., Baczko K., ter Meulen V., Billeter M. A. Biased hypermutation and other genetic changes in defective measles viruses in human brain infections. Cell. 55:1988;255-265.
6. Clarke P. A., Mathews M. B. Interactions between the double-stranded RNA binding motif and RNA: definition of the binding site for the interferon-induced protein kinase DAI (PKR) on adenovirus VA RNA. RNA. 1:1995;7-20.
7. Clemens M. J. Protein kinases that phosphorylate eIF-2 and eIF-2B, and their role in eukaryotic cell translational control. Translational Control. 1996;Cold Spring Harbor Laboratory Press, Cold Spring Harbor. p. 139-172.
8. Furtado M. R., Subramanian S., Bhat R. A., Fowlkes D. M., Safer B., Thimmappaya B. Functional dissection of adenovirus VAI RNA. J. Virol. 63:1989;3423-3434.
9. Green S. R., Mathews M. B. Two RNA binding motifs in the double-stranded RNA activated protein kinase, DAI. Genes Dev. 6:1992;2478-2490.
10. Green S. R., Manche L., Mathews M. B. Two functionally distinct RNA binding motifs in the regulatory domain of the protein kinase, DAI. Mol. Cell Biol. 15:1995;358-364.
11. Hough R. F., Bass B. L. Purification of theXenopus laevis. J. Biol. Chem. 269:1994;9933-9939.
12. Kim U., Garner T. L., Sanford T., Speicher D., Murray J. M., Nishikura K. Purification and characterization of double-stranded RNA adenosine deaminase from bovine nuclear extracts. J. Biol. Chem. 269:1994a;13480-13489.
13. Kim U., Wang Y., Sanford T., Zeng Y., Nishikura K. Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing. Proc. Natl. Acad. Sci. USA. 91:1994b;11457-11461.
14. Kitajewski J., Schneider R. J., Safer B., Munemitsu S. M., Samuel C. E., Thimmappaya B., Shenk T. Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2 alpha kinase. Cell. 45:1986;195-200.
15. Kuhen K. L., Shen X., Carlisle E. R., Richardson A. L., Weier H. U. G., Tanaka H., Samuel C. E. Mechanism of interferon action. Structural organization of the humanPkr. Genomics. 36:1996;197-201.
16. Kumar M., Carmichael G. G. Nuclear antisense RNA induces extensive adenosine modifications and nuclear retention of target transcripts. Proc. Natl. Acad. Sci. USA. 94:1997;3542-3547.
17. Lai F., Drakas R., Nishikura K. Mutagenic analysis of double-stranded RNA adenosine deaminase, a candidate enzyme for RNA editing of glutamate-gated ion channel transcripts. J. Biol. Chem. 270:1995;17098-17105.
18. Lengyel P. Tumor-suppressor genes: News about the interferon connection. Proc. Natl. Acad. Sci. USA. 90:1993;5893-5895.
19. Liu Y., Samuel C. E. Mechanism of interferon action: functionally distinct RNA-binding and catalytic domains in the interferon-inducible, double-stranded RNA-specific adenosine deaminase. J. Virol. 70:1996;1961-1968.
20. Liu Y., George C. X., Patterson J. B., Samuel C. E. Functionally distinct double-stranded RNA-binding domains associated with alternative splice-site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminase. J. Biol. Chem. 272:1997;4419-4428.
21. Lomeli H., Mosbacher J., Melcher T., Hoger T., Geiger J. R. P., Kuner T., Monyer H., Higuchi M., Bach A., Seeburg P. H. Control of kinetic properties of AMPA receptor channels by nuclear RNA editing. Science. 266:1994;1709-1713.
22. Luthman H., Magnusson G. High efficiency polyoma DNA transfection of chloroquine-treated cells. Nucleic Acids Res. 11:1983;1295-1308.
23. Ma Y., Mathews M. B. Structure, function, and evolution of adenovirus-associated RNA: A phylogenetic approach. J. Virol. 70:1996a;5083-5099.
24. Ma Y., Mathews M. B. Secondary and tertiary structure in the central domain of adenovirus type 2 VA RNA I. RNA. 2:1996b;937-951.
25. Maran A., Mathews M. B. Characterization of the double-stranded RNA implicated in the inhibition of protein synthesis in cells infected with a mutant adenovirus defective for VA RNA. Virology. 164:1988;106-113.
26. Mathews M. B., Shenk T. Adenovirus virus-associated RNA and translational control. J. Virol. 65:1991;5657-5662.
27. D. Virology. 206:1995;511-519.
28. McCormack S. J., Thomis D. C., Samuel C. E. Mechanism of interferon action: Identification of a RNA binding domain within the N-terminal region of the human RNA-dependent P1/eIF-2α protein kinase. Virology. 188:1992;47-56.
29. Meurs E., Chong K., Galabru J., Thomas N. S., Kerr I. M., Williams B. R. G., Hovanessian A. G. Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon. Cell. 62:1990;379-390.
30. Mellits K. H., Kostura M., Mathews M. B. Interaction of adenovirus VA RNAI with the protein kinase DAI-nonequivalence of binding and function. Cell. 61:1990;843-852.
31. Nishikura K., Yoo C., Kim U., Murray J. M., Estes P. A., Cash F. E., Liebhaber S. A. Substrate specificity of the dsRNA unwinding/modifying activity. EMBO J. 10:1991;3523-3532.
32. O'Connell M. A., Keller W. Purification and properties of double-stranded RNA-specific adenosine deaminase from calf thymus. Proc. Natl. Acad. Sci. USA. 91:1994;10596-10600.
33. O'Connell M. A., Krause S., Higuchi M., Hsuan J. J., Totty N. F., Jenny A., Keller W. Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase. Mol. Cell. Biol. 15:1995;1389-1397.
34. O'Malley R. P., Mariano T. M., Siekierka J., Mathews M. B. A mechanism for the control of protein synthesis by adenovirus VA RNAI. Cell. 44:1986;391-400.
35. Pathak V. K., Schindler D., Hershey J. W. B. Generation of a mutant form of protein synthesis initiation factor eIF-2 lacking the site of phosphorylation by eIF-2 kinases. Mol. Cell. Biol. 8:1988;993-995.
36. Patterson J. B., Thomis D. C., Hans S. L., Samuel C. E. Mechanism of interferon action. Double-stranded RNA-specific adenosine deaminase from human cells is inducible by alpha and gamma interferons. Virology. 210:1995;508-511.
37. Patterson J. B., Samuel C. E. Expression and regulation by interferon of a double-stranded RNA-specific adenosine deaminase from human cells: Evidence for two forms of the deaminase. Mol. Cell. Biol. 15:1995;5376-5388.
38. Polson A. G., Bass B. L. Preferential selection of adenosines for modification by double-stranded RNA adenosine deaminase. EMBO J. 13:1994;5701-5711.
39. Polson A. G., Bass B. L., Casey J. L. RNA editing of hepatitis delta virus antigenome by dsRNA-adenosine deaminase. Nature. 380:1996;454-456.
40. Rahman A., Malhotra P., Dhar R., Kewalramani T., Thimmapaya B. Effect of single-base substitutions in the central domain of virus-associated RNA I on its function. J. Virol. 69:1995;4299-4307.
41. Sambrook, J. Fritsch, E. F. Maniatis, T. 1989, Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Plainview, NY.
42. Samuel C. E. Mechanism of Interferon Action. Phosphorylation of protein synthesis initiation factor eIF-2 in interferon-treated human cells by a ribosome-associated protein kinase possessing site-specificity similar to hemin-regulated rabbit reticulocyte kinase. Proc. Natl. Acad. Sci. USA. 76:1979;600-604.
43. Samuel C. E. Antiviral actions of interferon. Interferon-regulated cellular proteins and their surprisingly selective antiviral activities. Virology. 183:1991;1-11.
44. Samuel C. E. The eIF-2α protein kinases, regulators of translation in eukaryotes from yeasts to humans. J. Biol. Chem. 268:1993;7603-7606.
45. Samuel C. E., Knutson G. S., Berry M. J., Atwater J. A., Lasky S. R. Purification of double stranded RNA-dependent protein kinase from mouse fibroblasts. Methods Enzymol. 119:1986;499-516.
46. Sanger F., Nicklen S., Coulson A. R. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA. 74:1977;5463-5467.
47. Scadden A. D. J., Smith C. W. J. A ribonuclease specific for inosine-containing RNA: A potential role in antiviral defence. EMBO J. 16:1997;2140-2149.
48. Schneider R. J., Weinberger C., Shenk T. Adenovirus VAI RNA facilitates the initiation of translation in virus-infected cells. Cell. 37:1984;291-298.
49. Sharmeen L., Bass B., Sonenberg N., Weintraub H., Groudine M. Tat-dependent adenosine-to-inosine modification of wild-type transactivation response RNA. Proc. Natl. Acad. Sci. USA. 88:1991;8096-8100.
50. Soderlund H., Pettersson U., Vennstrom B., Philipson L., Mathews M. B. A new species of virus-coded low molecular weight RNA from cells infected with adenovirus type 2. Cell. 7:1976;585-593.
51. Sommer B., Kohler M., Sprengel R., Seeburg P. H. RNA editing in brain controls a determinant of ion flow in glutamate-gated channels. Cell. 67:1991;11-19.
52. Stewart W. E. The Interferon System. 1979;Springer-Verlag, Berlin/New York.
53. St. Johnston D., Brown N. H., Gall J. G., Jantsch M. A conserved double-stranded RNA-binding domain. Proc. Natl. Acad. Sci. USA. 89:1992;10979-10983.
54. Strijker R., Fritz D. T., Levinson A. D. Adenovirus VAI-RNA regulates gene expression by controlling stability of ribosome-bound RNAs. EMBO J. 8:1989;2669-2675.
55. Svensson C., Akusjarvi G. A novel effect of adenovirus VA RNAI on cytoplasmic mRNA abundance. Virology. 174:1990;613-617.
56. Tanaka H., Samuel C. E. Mechanism of interferon action: Structure of the mouse PKR gene encoding the interferon-inducible RNA-dependent protein kinase. Proc. Natl. Acad. Sci. USA. 91:1994;7995-7999.
57. Thomis D. C., Doohan J. P., Samuel C. E. Mechanism of interferon action: cDNA structure, expression and regulation of the interferon-induced, RNA-dependent Pl/eIF-2α protein kinase from human cells. Virology. 188:1992;33-46.
58. Weier H-U. G., George C. X., Greulich K. M., Samuel C. E. The interferon-inducible, double-stranded RNA-specific adenosine deaminase gene (DSRAD) maps to human chromosome 1q21.1-21.2. Genomics. 30:1995;372-375.
59. Wong T. C., Ayata M., Hirano A., Yoshikawa Y., Tsuruoka H., Yamanouchi K. Generalized and localized biased hypermutation affecting the matrix gene of a measles virus strain that causes subacute sclerosing panencephalitis. J. Virol. 63:1989;5464-5468.
60. Zhou A., Hassel B. A., Silverman R. H. Expression cloning of 2-5A-dependent RNAase: A uniquely regulated mediator of interferon action. Cell. 72:1993;753-765.