Differential gene expression profiling of mouse skin after sulfur mustard exposure: Extended time response and inhibitor effect

Toxicology and Applied Pharmacology

Volumn 234, Issue 2, 2009, Pages 156-165

  Gerecke, Donald R ^a   Chen, Minjun ^a   Isukapalli, Sastry S ^a   Gordon, Marion K ^a   Chang, Yoke Chen ^a   Tong, Weida ^b   Androulakis, Ioannis P ^c   Georgopoulos, Panos G ^a  

^a RUTGERS UNIVERSITY   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^c RUTGERS UNIVERSITY   (United States)

Author keywords

Alkylating agent; Matrix metalloproteinase; Microarray; MMP; MMP inhibitor; Skin; Sulfur mustard; Vesicant

Indexed keywords

2 [(4 BIPHENYLYLSULFONYL)AMINO] 3 PHENYLPROPIONIC ACID; ALKYLATING AGENT; CELL ADHESION MOLECULE; CHEMICAL WARFARE AGENT; CYTOKINE RECEPTOR; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; MUSTARD GAS; PROTEIN P53; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLISTER; CHEMICAL STRUCTURE; CHEMOTAXIS; CLUSTER ANALYSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DERMOEPIDERMAL JUNCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION PROFILING; HEMATOPOIETIC CELL; IMMUNE RESPONSE; INFLAMMATION; ION TRANSPORT; MALE; MICROARRAY ANALYSIS; MOUSE; NEOPLASM; NONHUMAN; OXIDATIVE STRESS; PRINCIPAL COMPONENT ANALYSIS; PROTEIN GLYCOSYLATION; PUNCH BIOPSY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SKIN TOXICITY; SYNAPTOGENESIS;

ANIMALS; CARCINOGENS; CHEMICAL WARFARE AGENTS; CLUSTER ANALYSIS; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION PROFILING; MALE; MICE; MUSTARD GAS; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 58149457386     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2008.09.020     Document Type: Article

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