Preparation and swelling behavior of chitosan-based superporous hydrogels for gastric retention application

Journal of Biomedical Materials Research - Part A

Volumn 76, Issue 1, 2006, Pages 144-150

  Park, Hyojin ^a   Park, Kinam ^b   Kim, Dukjoon ^a  

^a Sungkyunkwan University   (South Korea)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Chitosan; Foaming; Hydrogel; Pore; Swelling

Indexed keywords

BIODEGRADATION; CROSSLINKING; GELATION; GLYCOLS; SOLUTIONS; SWELLING;

CHITOSAN; FOAMING; PORE;

HYDROGELS;

CHITOSAN;

ARTICLE; CROSS LINKING; DRUG DELIVERY SYSTEM; DRUG STRUCTURE; DRUG SYNTHESIS; FOAMING; GELATION; HYDROGEL; KINETICS; PH; POROSITY; STOMACH JUICE;

BIOCOMPATIBLE MATERIALS; BIODEGRADATION, ENVIRONMENTAL; CHITOSAN; DRUG DELIVERY SYSTEMS; HUMANS; HYDROGELS; KINETICS; MATERIALS TESTING; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; STOMACH;

EID: 30444435750     PISSN: 00219304     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbm.a.30533     Document Type: Article

References (20)

1. Mi FL, Tan YC, Liang HF, Sung HW. In vivo biocompatibility and degradability of a novel injectable-chitosan-based implant. Biomaterials 2002;23:181-191.
2. Simó C, Cifuentes A, Gallardo A. Drug delivery system: polymers and drugs monitored by capillary electromigration methods. J Chromatogr B 2003;797:37-49.
3. Sun Y, Peng Y, Chen Y, Shukla AJ. Application of artificial neural networks in the design of controlled release drug delivery systems. Adv Drug Delivery Rev 2003;55:1201-1215.
4. Risbud MV, Hardikar AA, Bhat SV, Bhonde RR. pH-sensitive freeze-dried chitosan-polyvinyl pyrrolidone hydrogels as controlled release system for antibiotic delivery. J Control Release 200;68:23-30.
5. Chen J, Blevins WE, Park H, Park K. Gastric retention properties of superporous hydrogel composites. J Control Release 2000;64:39-51.
6. Zhang XZ, Wu DQ, Chu CC. Synthesis, characterization and controlled drug release of thermosensitive IPN-PNIPAAm hydrogels. Biomaterials 2004;25:3793-3805.
7. Qiu Y, Park K. Environment-sensitive hydrogels for drug delivery. Adv Drug Delivery Rev 2001;53:321-339.
8. Karadag E, Uzum OB, Saraydin D. Swelling equilibria and dye absorption studies of chemically crosslinked superabsorbent acrylamide/maleic acid hydrogels. Eur Polym J 2002;38:2133-2141.
9. Chen J, Park H, Park K. Synthesis of superporous hydrogels: hydrogels with fast swelling and superabsorbent properties. J Biomed Mater Res 1999;44:53-62.
10. Dorkoosh FA, Brussee J, Verhoef JC, Borchard G, Rafiee-Tehrani M, Junginger HE. Preparation and NMR characterization of superporous hydrogels (SPH) and SPH composites. Polymer 2000;41:8213-8220.
11. Chen J, Park H, Park K. Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties. US patent no. 6271278131, 2001.
12. Rodriguez K, Alvarez-Loreuzo C, Concheiro A. Cationic cellulose hydrogels: kinetics of the cross-linking process and characterization as pH-/ion-sensitive drug delivery systems. J Control Release 2003;86:253-265.
13. Kabiri K, Omidian H, Hashemi SA, Zohuriaan-Mehr MJ. Synthesis of fast-swelling superabsorbent hydrogels: effect of crosslinker type and concentration on porosity and absorption rate. Eur Polym J 2003;39:1341-1348.
14. Majeti NV, Ravi K. A review of chitin and chitosan applications. React Funct Polym 2000;46:1-27.
15. Hejazi R, Amiji M. Chitosan-based gastrointestinal delivery systems. J Control Release 2003;89:151-165.
16. Robert GAF. Chitin chemistry. London: Macmillan; 1992. p. 305-315.
17. Mi FL, Kuan CY, Shyu SS, Lee ST, Chang SF. The study of gelation kinetics and chain-relaxation properties of glutaraldehyde-cross-linked chitosan gel and their effects on microspheres preparation and drug release. Carbohydrate Polym 2000;41:389-396.
18. Lee M, Clire GW, Fariba K, Laureuce T, Alexander IG, Sevda S, Ijeoma FU. The release of model macromolecules may be controlled by the hydrophobicity of palmitoyl glycol chitosan hydrogels. J Control Release 2002;80:87-100.
19. Hirano S, Seino H, Akjyama Y, Nonaka I. Progress in biomedical polymers. New York: Plenum; 1990. p. 283.
20. Lorna N, Alexander IG, Lubna S, Ijeoma FU. A non-covalently cross-linked chitosan based hydrogel. Int J Pharm 1999;192: 173-182.