Differential role of human choline kinase α and β enzymes in lipid metabolism: Implications in cancer onset and treatment

PLoS ONE

Volumn 4, Issue 11, 2009, Pages

  Gallego Ortega, David ^a   de Molina, Ana Ramirez ^a,b   Ramos, Maria Angeles ^a,b   Valdes Mora, Fatima ^a   Barderas, Maria Gonzalez ^c   Sarmentero Estrada, Jacinto ^a,b   Lacal, Juan Carlos ^a,b  

^a CSIC   (Spain)

^b CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^c HOSPITAL NACIONAL DE PARAPLÉJICOS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE KINASE; CHOLINE KINASE ALPHA; CHOLINE KINASE BETA; ETHANOLAMINE KINASE; ISOPROTEIN; MESSENGER RNA; UNCLASSIFIED DRUG; ETHANOLAMINE DERIVATIVE; PHOSPHOETHANOLAMINE; PHOSPHORYLCHOLINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER THERAPY; CARCINOGENESIS; CELL TRANSFORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPID METABOLISM; LUNG CANCER; NONHUMAN; NUCLEOTIDE SEQUENCE; TUMOR GROWTH; UPREGULATION; ALTERNATIVE RNA SPLICING; ANIMAL; CELL MEMBRANE; CHEMISTRY; DOG; ENZYMOLOGY; KINETICS; METABOLISM; NEOPLASM; PHYSIOLOGY; TUMOR CELL LINE;

ALTERNATIVE SPLICING; ANIMALS; CELL LINE, TUMOR; CELL MEMBRANE; CHOLINE KINASE; DOGS; ETHANOLAMINES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KINETICS; LIPID METABOLISM; NEOPLASMS; PHOSPHORYLCHOLINE; PROTEIN ISOFORMS;

EID: 70649104039     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007819     Document Type: Article

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