Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

Drug metabolism and pharmacokinetics

Volumn 20, Issue 5, 2005, Pages 379-386

  Kimura, Naoko ^a   Masuda, Satohiro ^a   Tanihara, Yuko ^a   Ueo, Harumasa ^a   Okuda, Masahiro ^a   Katsura, Toshiya ^a   Inui, Ken Ichi ^a  

^a KYOTO UNIVERSITY HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; METFORMIN; ORGANIC CATION TRANSPORTER; ORGANIC CATION TRANSPORTER 1; SLC22A2 PROTEIN, HUMAN;

ANIMAL; ARTICLE; BLOOD; CELL LINE; FEMALE; GENETIC TRANSFECTION; GENETICS; HUMAN; KIDNEY; LIVER; MALE; METABOLISM; RAT; TISSUE DISTRIBUTION; TRANSPORT AT THE CELLULAR LEVEL; WISTAR RAT;

ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; DNA, COMPLEMENTARY; FEMALE; HUMANS; KIDNEY; LIVER; MALE; METFORMIN; ORGANIC CATION TRANSPORT PROTEINS; ORGANIC CATION TRANSPORTER 1; RATS; RATS, WISTAR; RNA, MESSENGER; TISSUE DISTRIBUTION; TRANSFECTION;

EID: 33644664085     PISSN: 13474367     EISSN: None     Source Type: Journal    
DOI: 10.2133/dmpk.20.379     Document Type: Article

References (0)