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Volumn 4, Issue , 2009, Pages 20-

Ginseng leaf-stem: Bioactive constituents and pharmacological functions

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; ATRIAL NATRIURETIC FACTOR; BASIC FIBROBLAST GROWTH FACTOR; ESSENTIAL OIL; FATTY ACID DERIVATIVE; FLAVONOID; GINSENG EXTRACT; GINSENOSIDE; PEPTIDE DERIVATIVE; POLYACETYLENE DERIVATIVE; POLYSACCHARIDE; TRITERPENOID;

EID: 70450278777     PISSN: None     EISSN: 17498546     Source Type: Journal    
DOI: 10.1186/1749-8546-4-20     Document Type: Article
Times cited : (109)

References (84)
  • 1
    • 0345583507 scopus 로고    scopus 로고
    • Encyclopedia of herbal medicine
    • New York: DK Publishing Inc
    • Chevallier A. Encyclopedia of herbal medicine. 2000, New York: DK Publishing Inc.
    • (2000)
    • Chevallier, A.1
  • 2
    • 51749111854 scopus 로고    scopus 로고
    • Ginseng: beneficial and potential adverse effect
    • Boca Raton, London, New York, Washington, DC: CRC Press Company, Yuan C-S, Beiber E, Bauer BA
    • Xie J-T, Attele AS, Yuan C-S. Ginseng: beneficial and potential adverse effect. A textbook of complementary and alternative therapies 2006, 71-89. Boca Raton, London, New York, Washington, DC: CRC Press Company, Yuan C-S, Beiber E, Bauer BA.
    • (2006) A textbook of complementary and alternative therapies , pp. 71-89
    • Xie, J.-T.1    Attele, A.S.2    Yuan, C.-S.3
  • 3
    • 0026674127 scopus 로고
    • Purification of an anti-ulcer polysaccharide from the leaves of Panax ginseng
    • 10.1055/s-2006-961510, 1470669
    • Sun XB, Matsumoto T, Yamada H. Purification of an anti-ulcer polysaccharide from the leaves of Panax ginseng. Planta Med 1992, 58:445-448. 10.1055/s-2006-961510, 1470669.
    • (1992) Planta Med , vol.58 , pp. 445-448
    • Sun, X.B.1    Matsumoto, T.2    Yamada, H.3
  • 4
    • 0030757369 scopus 로고    scopus 로고
    • Panax ginseng pharmacology: a nitric oxide link?
    • 10.1016/S0006-2952(97)00193-7, 9296344
    • Gillis CN. Panax ginseng pharmacology: a nitric oxide link?. Biochem Pharmacol 1997, 54(1):1-8. 10.1016/S0006-2952(97)00193-7, 9296344.
    • (1997) Biochem Pharmacol , vol.54 , Issue.1 , pp. 1-8
    • Gillis, C.N.1
  • 5
    • 0032573627 scopus 로고    scopus 로고
    • Panax quinquefolium saponins protects low density lipoproteins from oxidation
    • 10.1016/S0024-3205(98)00533-5, 10027742
    • Li J, Huang M, Teoh H, Man RY. Panax quinquefolium saponins protects low density lipoproteins from oxidation. Life Sci 1999, 64(1):53-62. 10.1016/S0024-3205(98)00533-5, 10027742.
    • (1999) Life Sci , vol.64 , Issue.1 , pp. 53-62
    • Li, J.1    Huang, M.2    Teoh, H.3    Man, R.Y.4
  • 6
    • 0034047551 scopus 로고    scopus 로고
    • Antioxidant and anti-tumor promoting activities of the methanol extract of heat-precessed ginseng
    • 10.1016/S0304-3835(99)00369-9, 10755385
    • Keum YS, Park KK, Lee JM, Chun KS, Park JH, Lee SK, Kwon H, Surh YJ. Antioxidant and anti-tumor promoting activities of the methanol extract of heat-precessed ginseng. Cancer Letters 2000, 150:41-48. 10.1016/S0304-3835(99)00369-9, 10755385.
    • (2000) Cancer Letters , vol.150 , pp. 41-48
    • Keum, Y.S.1    Park, K.K.2    Lee, J.M.3    Chun, K.S.4    Park, J.H.5    Lee, S.K.6    Kwon, H.7    Surh, Y.J.8
  • 7
    • 0037116642 scopus 로고    scopus 로고
    • Recent patterns of medication use in the ambulatory adult population of the United States
    • 10.1001/jama.287.3.337, 11790213
    • Kaufman DW, Kelly JP, Rosenberg L, Anderson TE, Mitchell AA. Recent patterns of medication use in the ambulatory adult population of the United States. JAMA 2002, 287:337-344. 10.1001/jama.287.3.337, 11790213.
    • (2002) JAMA , vol.287 , pp. 337-344
    • Kaufman, D.W.1    Kelly, J.P.2    Rosenberg, L.3    Anderson, T.E.4    Mitchell, A.A.5
  • 8
    • 0037139391 scopus 로고    scopus 로고
    • Free redical scavenging activity of red ginseng aqueous extracts
    • 10.1016/S0300-483X(01)00585-6, 11882354
    • Kim YK, Guo Q, Packer L. Free redical scavenging activity of red ginseng aqueous extracts. Toxicology 2002, 172:149-156. 10.1016/S0300-483X(01)00585-6, 11882354.
    • (2002) Toxicology , vol.172 , pp. 149-156
    • Kim, Y.K.1    Guo, Q.2    Packer, L.3
  • 9
    • 38549156045 scopus 로고    scopus 로고
    • Safety and efficacy of panax ginseng during pregnancy and lactation
    • Seely D, Dugoua JJ, Perri D, Mills E, Koren G. Safety and efficacy of panax ginseng during pregnancy and lactation. Can J Clin Pharmacol 2008, 15(1):87-94.
    • (2008) Can J Clin Pharmacol , vol.15 , Issue.1 , pp. 87-94
    • Seely, D.1    Dugoua, J.J.2    Perri, D.3    Mills, E.4    Koren, G.5
  • 10
    • 0034722756 scopus 로고    scopus 로고
    • Panax (ginseng) is not a panacea
    • 10.1001/archinte.160.21.3329, 11088100
    • Cheng TO. Panax (ginseng) is not a panacea. Arch Intern Med 2000, 160:3329-3330. 10.1001/archinte.160.21.3329, 11088100.
    • (2000) Arch Intern Med , vol.160 , pp. 3329-3330
    • Cheng, T.O.1
  • 11
    • 0344549853 scopus 로고    scopus 로고
    • Ginseng pharmacology: multiple constituents and multiple actions
    • 10.1016/S0006-2952(99)00212-9, 10571242
    • Attele AS, Wu JA, Yuan CS. Ginseng pharmacology: multiple constituents and multiple actions. Biochem Pharmacol 1999, 58(11):1685-1693. 10.1016/S0006-2952(99)00212-9, 10571242.
    • (1999) Biochem Pharmacol , vol.58 , Issue.11 , pp. 1685-1693
    • Attele, A.S.1    Wu, J.A.2    Yuan, C.S.3
  • 12
    • 0032771906 scopus 로고    scopus 로고
    • Tyrosinase inhibitory p-coumaric acid from ginseng leaves
    • 10.1002/(SICI)1099-1573(199908/09)13:5<371::AID-PTR453>3.0.CO;2-L, 10441774
    • Lim J-Y, Ishiguro K, Kubo I. Tyrosinase inhibitory p-coumaric acid from ginseng leaves. Phytother Res 1999, 13:371-375. 10.1002/(SICI)1099-1573(199908/09)13:5<371::AID-PTR453>3.0.CO;2-L, 10441774.
    • (1999) Phytother Res , vol.13 , pp. 371-375
    • Lim, J.-Y.1    Ishiguro, K.2    Kubo, I.3
  • 14
    • 0017596870 scopus 로고
    • The chemical constituents of ginseng plants
    • Hou JP. The chemical constituents of ginseng plants. Comp Med East and West 1977, 5:123-145.
    • (1977) Comp Med East and West , vol.5 , pp. 123-145
    • Hou, J.P.1
  • 15
    • 0021780126 scopus 로고
    • Quantitative analysis of ginsenosides in fresh Panax ginseng
    • 10.1142/S0192415X85000125, 4025218
    • Yip TT, Lau CN, But PP, Kong YC. Quantitative analysis of ginsenosides in fresh Panax ginseng. Am J Chin Med 1985, 13:77-88. 10.1142/S0192415X85000125, 4025218.
    • (1985) Am J Chin Med , vol.13 , pp. 77-88
    • Yip, T.T.1    Lau, C.N.2    But, P.P.3    Kong, Y.C.4
  • 16
    • 24744443405 scopus 로고    scopus 로고
    • Zhonghua Bencao (Chinese Herbal Medicine)
    • Shanghai: Shanghai Science and Technology House
    • Zhonghua Bencao Editors Zhonghua Bencao (Chinese Herbal Medicine). 1996, Shanghai: Shanghai Science and Technology House.
    • (1996)
  • 17
    • 0004186883 scopus 로고    scopus 로고
    • The Pharmacology of Chinese Herbs
    • Boca Raton, FL: CRC Press
    • Huang KC. The Pharmacology of Chinese Herbs. 1999, Boca Raton, FL: CRC Press.
    • (1999)
    • Huang, K.C.1
  • 18
    • 0034398404 scopus 로고    scopus 로고
    • Ginsenoside-Rg6, a novel triterpenoid saponin from the stem-leaves of Panax ginseng C. A. Mey
    • Yang XW, Li LY, Tian JM, Zhang ZW, Ye JM, Gu WF. Ginsenoside-Rg6, a novel triterpenoid saponin from the stem-leaves of Panax ginseng C. A. Mey. Chinese Chemical Letters 2000, 11:909-912.
    • (2000) Chinese Chemical Letters , vol.11 , pp. 909-912
    • Yang, X.W.1    Li, L.Y.2    Tian, J.M.3    Zhang, Z.W.4    Ye, J.M.5    Gu, W.F.6
  • 19
    • 0035064619 scopus 로고    scopus 로고
    • Six new dammarane-type triterpene saponins from the leaves of Panax ginseng
    • 10.1248/cpb.49.442, 11310671
    • Dou DQC, Liang YJ, Pang LH, Shimizu FG, N Takeda T. Six new dammarane-type triterpene saponins from the leaves of Panax ginseng. Chem Pharm Bull 2001, 49:442-446. 10.1248/cpb.49.442, 11310671.
    • (2001) Chem Pharm Bull , vol.49 , pp. 442-446
    • Dou, D.Q.C.1    Liang, Y.J.2    Pang, L.H.3    Shimizu, F.G.4    N Takeda, T.5
  • 20
    • 21344471467 scopus 로고    scopus 로고
    • Identification of ginsenosides in roots of Panax ginseng by HPLC-APCI/MS
    • 10.1002/pca.842, 15997851
    • Ma XQ, Liang XM, Xu Q, Zhang XZ, Xiao HB. Identification of ginsenosides in roots of Panax ginseng by HPLC-APCI/MS. Phytochem Anal 2005, 16(3):181-187. 10.1002/pca.842, 15997851.
    • (2005) Phytochem Anal , vol.16 , Issue.3 , pp. 181-187
    • Ma, X.Q.1    Liang, X.M.2    Xu, Q.3    Zhang, X.Z.4    Xiao, H.B.5
  • 21
    • 0344010209 scopus 로고    scopus 로고
    • American ginseng leaf: Ginsenoside analysis and hypoglycemic activity
    • 10.1016/j.phrs.2003.07.015, 14643691
    • Xie JT, Mehendale SR, Wang A, Aung HH, Wu J, Osinski J, Yuan C-S. American ginseng leaf: Ginsenoside analysis and hypoglycemic activity. Pharmacol Res 2004, 49:113-117. 10.1016/j.phrs.2003.07.015, 14643691.
    • (2004) Pharmacol Res , vol.49 , pp. 113-117
    • Xie, J.T.1    Mehendale, S.R.2    Wang, A.3    Aung, H.H.4    Wu, J.5    Osinski, J.6    Yuan, C.-S.7
  • 22
    • 0036203633 scopus 로고    scopus 로고
    • Seasonal fluctuations of leaf and root weight and ginsenosides contents of 2-, 3-, and 4-year-old American ginseng plants
    • Li TSCWD. Seasonal fluctuations of leaf and root weight and ginsenosides contents of 2-, 3-, and 4-year-old American ginseng plants. HortTechnology 2002, 12:229-232.
    • (2002) HortTechnology , vol.12 , pp. 229-232
    • Li, T.S.C.W.D.1
  • 23
    • 27744506598 scopus 로고    scopus 로고
    • Ginsenoside content of North American ginseng (Panax quinquefolius L. Araliaceae) in relation to plant development and growing locations
    • Jackson CJC, Dini JP, Lavandier C, Faulkner H, Rupasinghe HPV, Proctor JTA. Ginsenoside content of North American ginseng (Panax quinquefolius L. Araliaceae) in relation to plant development and growing locations. J Ginseng Research 2003, 27:135-140.
    • (2003) J Ginseng Research , vol.27 , pp. 135-140
    • Jackson, C.J.C.1    Dini, J.P.2    Lavandier, C.3    Faulkner, H.4    Rupasinghe, H.P.V.5    Proctor, J.T.A.6
  • 24
    • 0042303946 scopus 로고    scopus 로고
    • Phytochemistry of Wild Populations of Panax quinquefolius L. (North American Ginseng)
    • 10.1021/jf030042h, 14705875
    • Assinewe VA, Baum BR, Gagnon D, Arnason JT. Phytochemistry of Wild Populations of Panax quinquefolius L. (North American Ginseng). J Agric Food Chem 2003, 51:4549-4553. 10.1021/jf030042h, 14705875.
    • (2003) J Agric Food Chem , vol.51 , pp. 4549-4553
    • Assinewe, V.A.1    Baum, B.R.2    Gagnon, D.3    Arnason, J.T.4
  • 25
    • 33645759774 scopus 로고    scopus 로고
    • Saponins composition in american ginseng leaf and berry assayed by high-performance liquid chromatography
    • 10.1021/jf052993w, 16536605
    • Wang CZ, Wu JA, McEntee E, Yuan CS. Saponins composition in american ginseng leaf and berry assayed by high-performance liquid chromatography. J Agric Food Chem 2006, 54(6):2261-2266. 10.1021/jf052993w, 16536605.
    • (2006) J Agric Food Chem , vol.54 , Issue.6 , pp. 2261-2266
    • Wang, C.Z.1    Wu, J.A.2    McEntee, E.3    Yuan, C.S.4
  • 26
    • 33749343251 scopus 로고    scopus 로고
    • [Determination of 20 (S)-ginsengnoside Rh2 in the alkali-hydrolysis product of saponins from leaves of Panax qinquefolium by RP-HPLC]
    • Li XW, Gui MY, Zheng Y, Jin YR, Zhang HQ. [Determination of 20 (S)-ginsengnoside Rh2 in the alkali-hydrolysis product of saponins from leaves of Panax qinquefolium by RP-HPLC]. Zhongguo Zhong Yao Za Zhi 2006, 31(5):386-388.
    • (2006) Zhongguo Zhong Yao Za Zhi , vol.31 , Issue.5 , pp. 386-388
    • Li, X.W.1    Gui, M.Y.2    Zheng, Y.3    Jin, Y.R.4    Zhang, H.Q.5
  • 27
    • 33846195802 scopus 로고    scopus 로고
    • Investigation of ginsenosides in different parts and ages of Panax ginseng
    • Shi W, Wang Y, Li J, Zhang H, Ding L. Investigation of ginsenosides in different parts and ages of Panax ginseng. Food Chemistry 2007, 102:664-668.
    • (2007) Food Chemistry , vol.102 , pp. 664-668
    • Shi, W.1    Wang, Y.2    Li, J.3    Zhang, H.4    Ding, L.5
  • 28
    • 34548619447 scopus 로고    scopus 로고
    • Construction of the fingerprints of ginseng stem and leaf saponin reference substances and spiked plasma sample by LC-ESI/MS and its application to analyzing the compounds absorbed into blood after oral administration of ginseng stem and leaf saponin in rat
    • 10.1248/bpb.30.1657, 17827716
    • Yan B, Wang G, A J, Xie L, Hao H, Liang Y, Sun J, Li X, Zheng Y. Construction of the fingerprints of ginseng stem and leaf saponin reference substances and spiked plasma sample by LC-ESI/MS and its application to analyzing the compounds absorbed into blood after oral administration of ginseng stem and leaf saponin in rat. Biol Pharm Bull 2007, 30(9):1657-1662. 10.1248/bpb.30.1657, 17827716.
    • (2007) Biol Pharm Bull , vol.30 , Issue.9 , pp. 1657-1662
    • Yan, B.1    Wang, G.2    Xie, L.3    Hao, H.4    Liang, Y.5    Sun, J.6    Li, X.7    Zheng, Y.8
  • 29
    • 35448991368 scopus 로고    scopus 로고
    • A new compound from the leaves of Panax ginseng
    • 10.1016/j.fitote.2007.06.002, 17643867
    • Wu LJ, Wang LB, Gao HY, Wu B, Song XM, Tang ZS. A new compound from the leaves of Panax ginseng. Fitoterapia 2007, 78(7-8):556-560. 10.1016/j.fitote.2007.06.002, 17643867.
    • (2007) Fitoterapia , vol.78 , Issue.7-8 , pp. 556-560
    • Wu, L.J.1    Wang, L.B.2    Gao, H.Y.3    Wu, B.4    Song, X.M.5    Tang, Z.S.6
  • 30
    • 0015894134 scopus 로고
    • Pharmacological studies of panax ginseng leaves
    • Saqito H, Morita M, Takagi K. Pharmacological studies of panax ginseng leaves. Japan J Pharmacol 1973, 23:43-56.
    • (1973) Japan J Pharmacol , vol.23 , pp. 43-56
    • Saqito, H.1    Morita, M.2    Takagi, K.3
  • 31
    • 0019120313 scopus 로고
    • Antidiuretic effect of ginsenosides of the stems and leaves of Panax ginseng (author's transl)
    • Wang BX, Cui JC, Liu AJ. Antidiuretic effect of ginsenosides of the stems and leaves of Panax ginseng (author's transl). Zhongguo Yao Li Xue Bao 1980, 1(2):126-130.
    • (1980) Zhongguo Yao Li Xue Bao , vol.1 , Issue.2 , pp. 126-130
    • Wang, B.X.1    Cui, J.C.2    Liu, A.J.3
  • 32
    • 0020407407 scopus 로고
    • The action of ginsenosides extracted from the stems and leaves of Panax ginseng in promoting animal growth
    • Wang BX, Cui JC, Liu AJ. The action of ginsenosides extracted from the stems and leaves of Panax ginseng in promoting animal growth. Yao Hsueh Hsueh Pao 1982, 17(12):899-904.
    • (1982) Yao Hsueh Hsueh Pao , vol.17 , Issue.12 , pp. 899-904
    • Wang, B.X.1    Cui, J.C.2    Liu, A.J.3
  • 33
    • 0029349342 scopus 로고
    • Effects of Chinese ginseng root and stem-leaf saponins on learning, memory and biogenic monoamines of brain in rats
    • Wang A, Gao Y, Wang Y, Zhao R, Liu C. Effects of Chinese ginseng root and stem-leaf saponins on learning, memory and biogenic monoamines of brain in rats. Zhongguo Zhong Yao Za Zhi 1995, 20:493-495.
    • (1995) Zhongguo Zhong Yao Za Zhi , vol.20 , pp. 493-495
    • Wang, A.1    Gao, Y.2    Wang, Y.3    Zhao, R.4    Liu, C.5
  • 34
    • 0025875581 scopus 로고
    • Effects of ginseng stem-laef saponins on one-way avoidance behavior in rats
    • Ma TC, Yu QH, Chen MH. Effects of ginseng stem-laef saponins on one-way avoidance behavior in rats. Acta Pharmacol Sinica 1991, 12:403-406.
    • (1991) Acta Pharmacol Sinica , vol.12 , pp. 403-406
    • Ma, T.C.1    Yu, Q.H.2    Chen, M.H.3
  • 35
    • 0035206872 scopus 로고    scopus 로고
    • Constituents and pharmacological effects of Eucommia and Siberian ginseng
    • Deyama TN, S Najazawa Y. Constituents and pharmacological effects of Eucommia and Siberian ginseng. Acta Pharmacol Sin 2001, 22:1057-1070.
    • (2001) Acta Pharmacol Sin , vol.22 , pp. 1057-1070
    • Deyama, T.N.1    S Najazawa, Y.2
  • 37
    • 33645281711 scopus 로고    scopus 로고
    • Effects of ginsenosides extracted from ginseng stem and leaves on glucocorticoid receptor in different viscera in heat-damaged rats
    • 10.3736/jcim20060210, 16529692
    • Li M, Ling CQ, Huang XQ, Shen ZL. Effects of ginsenosides extracted from ginseng stem and leaves on glucocorticoid receptor in different viscera in heat-damaged rats. Zhong Xi Yi Jie He Xue Bao 2006, 4(2):156-159. 10.3736/jcim20060210, 16529692.
    • (2006) Zhong Xi Yi Jie He Xue Bao , vol.4 , Issue.2 , pp. 156-159
    • Li, M.1    Ling, C.Q.2    Huang, X.Q.3    Shen, Z.L.4
  • 39
    • 0035384621 scopus 로고    scopus 로고
    • Protective effect of Panax quinquefolium 20s-proto-panaxdiolsaponins on acute myocardial infarction in dogs
    • Sui DY, Yu XF, Qu SC, Lu ZZ, Wang L, Chen MQ. Protective effect of Panax quinquefolium 20s-proto-panaxdiolsaponins on acute myocardial infarction in dogs. Zhongguo Zhong Yao Za Zhi 2001, 26(6):416-419.
    • (2001) Zhongguo Zhong Yao Za Zhi , vol.26 , Issue.6 , pp. 416-419
    • Sui, D.Y.1    Yu, X.F.2    Qu, S.C.3    Lu, Z.Z.4    Wang, L.5    Chen, M.Q.6
  • 40
    • 47749140444 scopus 로고    scopus 로고
    • Effect of panax quinquefolius saponin on angiogenesis and expressions of VEGF and bFGF in myocardium of rats with acute myocardial infarction
    • Wang CL, Shi DZ, Yin HJ. Effect of panax quinquefolius saponin on angiogenesis and expressions of VEGF and bFGF in myocardium of rats with acute myocardial infarction. Zhongguo Zhong Xi Yi Jie He Za Zhi 2007, 27(4):331-334.
    • (2007) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.27 , Issue.4 , pp. 331-334
    • Wang, C.L.1    Shi, D.Z.2    Yin, H.J.3
  • 41
    • 0032790389 scopus 로고    scopus 로고
    • Beneficial effects of ginsenosides of stems and leaves on cardiac and coronary vascular functions after 12-hour rat heart preservation
    • 10.1016/S0041-1345(99)00299-7, 10456006
    • Zhang J-M, Matsuura Y, Sueda T, Orihashi K. Beneficial effects of ginsenosides of stems and leaves on cardiac and coronary vascular functions after 12-hour rat heart preservation. Transplantation proceedings 1999, 31:2175-2178. 10.1016/S0041-1345(99)00299-7, 10456006.
    • (1999) Transplantation proceedings , vol.31 , pp. 2175-2178
    • Zhang, J.-M.1    Matsuura, Y.2    Sueda, T.3    Orihashi, K.4
  • 42
    • 0030177394 scopus 로고    scopus 로고
    • Effects of saponins from stems and leaves of Panax quinquefolium L. on the contraction of rabbit aortic strips
    • Guan L, Yi X, Feng Q, Yang L. Effects of saponins from stems and leaves of Panax quinquefolium L. on the contraction of rabbit aortic strips. Zhongguo Zhong Yao Za Zhi 1996, 20:431-434.
    • (1996) Zhongguo Zhong Yao Za Zhi , vol.20 , pp. 431-434
    • Guan, L.1    Yi, X.2    Feng, Q.3    Yang, L.4
  • 44
    • 0025503834 scopus 로고
    • Clinical and experimental stydy of shenshao tongguan pian in treating angina pectoris of coronary heart disease
    • Hu JX, Jia GX, Yan ZR. Clinical and experimental stydy of shenshao tongguan pian in treating angina pectoris of coronary heart disease. Zhong Xi Yi Jie He ZA Zhi 1990, 10:596-599.
    • (1990) Zhong Xi Yi Jie He ZA Zhi , vol.10 , pp. 596-599
    • Hu, J.X.1    Jia, G.X.2    Yan, Z.R.3
  • 45
    • 0026132605 scopus 로고
    • Effects of ageing and ginsenoside on atrial natriuretic peptide gene expression
    • Hong M. Effects of ageing and ginsenoside on atrial natriuretic peptide gene expression. Zhonghua Yi Xue Za Zhi 1991, 71:140-143.
    • (1991) Zhonghua Yi Xue Za Zhi , vol.71 , pp. 140-143
    • Hong, M.1
  • 46
    • 0026567525 scopus 로고
    • The decline of atrial natriuretic peptide (ANP) gene expression in older rats and the effects of ginsenoside on ANP gene expression
    • 10.1016/0305-0491(92)90155-K, 1386796
    • Hong M, Jin Y, Mai YQ, Boersma A, Han KK, Vantyghem MC, Lefebere J. The decline of atrial natriuretic peptide (ANP) gene expression in older rats and the effects of ginsenoside on ANP gene expression. Comp Biochem Physiol B 1992, 101:35-39. 10.1016/0305-0491(92)90155-K, 1386796.
    • (1992) Comp Biochem Physiol B , vol.101 , pp. 35-39
    • Hong, M.1    Jin, Y.2    Mai, Y.Q.3    Boersma, A.4    Han, K.K.5    Vantyghem, M.C.6    Lefebere, J.7
  • 47
    • 0033007265 scopus 로고    scopus 로고
    • Effect of aerobic exercise and ginsenosides on lipid metabolism in diet-induced hyperlipidemia mice
    • Yang Y, Wu T, He K, Fu ZG. Effect of aerobic exercise and ginsenosides on lipid metabolism in diet-induced hyperlipidemia mice. Acta Pharmacol Sin 1999, 20:563-565.
    • (1999) Acta Pharmacol Sin , vol.20 , pp. 563-565
    • Yang, Y.1    Wu, T.2    He, K.3    Fu, Z.G.4
  • 48
    • 0030177486 scopus 로고    scopus 로고
    • Effects of ginsenosides from stems and leaves on hyperlipemia induced by prednisone acetate in rabbits
    • Wen Y, Pei Y, Chen Y, Wang Z, Ma Z, Wang M, Li W. Effects of ginsenosides from stems and leaves on hyperlipemia induced by prednisone acetate in rabbits. Zhongguo Zhong Yao Za Zhi 1996, 21:430-431.
    • (1996) Zhongguo Zhong Yao Za Zhi , vol.21 , pp. 430-431
    • Wen, Y.1    Pei, Y.2    Chen, Y.3    Wang, Z.4    Ma, Z.5    Wang, M.6    Li, W.7
  • 49
    • 34748921692 scopus 로고    scopus 로고
    • Importance of cultural issues in managing a patient with diabetes
    • Shane-McWhorter L, Oderda LH. Importance of cultural issues in managing a patient with diabetes. Consult Pharm 2007, 22(5):431-437.
    • (2007) Consult Pharm , vol.22 , Issue.5 , pp. 431-437
    • Shane-McWhorter, L.1    Oderda, L.H.2
  • 50
    • 0029097005 scopus 로고
    • Ginseng therapy in non-insulin-dependent diabetic patients
    • 10.2337/diacare.18.10.1373, 8721940
    • Sotaniemi EA, Haapakoski E, Rautio A. Ginseng therapy in non-insulin-dependent diabetic patients. Diabetes Care 1995, 18(10):1373-1375. 10.2337/diacare.18.10.1373, 8721940.
    • (1995) Diabetes Care , vol.18 , Issue.10 , pp. 1373-1375
    • Sotaniemi, E.A.1    Haapakoski, E.2    Rautio, A.3
  • 51
    • 0034630423 scopus 로고    scopus 로고
    • American ginseng (Panax quinquefolius L) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus
    • 10.1001/archinte.160.7.1009, 10761967
    • Vuksan V, Sievenpiper JL, Koo VY, Francis T, Beljan-Zdravkovic U, Xu Z, Vidgen E. American ginseng (Panax quinquefolius L) reduces postprandial glycemia in nondiabetic subjects and subjects with type 2 diabetes mellitus. Arch Intern Med 2000, 160(7):1009-1013. 10.1001/archinte.160.7.1009, 10761967.
    • (2000) Arch Intern Med , vol.160 , Issue.7 , pp. 1009-1013
    • Vuksan, V.1    Sievenpiper, J.L.2    Koo, V.Y.3    Francis, T.4    Beljan-Zdravkovic, U.5    Xu, Z.6    Vidgen, E.7
  • 53
    • 0035380884 scopus 로고    scopus 로고
    • Comparisons between white ginseng radix and rootlet for antidiabetic activity and mechanism in KKAy mice
    • 10.1007/BF02978260, 11440080
    • Chung SH, Choi CG, Park SH. Comparisons between white ginseng radix and rootlet for antidiabetic activity and mechanism in KKAy mice. Arch Pharm Res 2001, 24(3):214-218. 10.1007/BF02978260, 11440080.
    • (2001) Arch Pharm Res , vol.24 , Issue.3 , pp. 214-218
    • Chung, S.H.1    Choi, C.G.2    Park, S.H.3
  • 54
    • 0036266324 scopus 로고    scopus 로고
    • Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component
    • 10.2337/diabetes.51.6.1851, 12031973
    • Attele AS, Zhou YP, Xie JT, Wu JA, Zhang L, Dey L, Pugh W, Rue PA, Polonsky KS, Yuan CS. Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component. Diabetes 2002, 51(6):1851-1858. 10.2337/diabetes.51.6.1851, 12031973.
    • (2002) Diabetes , vol.51 , Issue.6 , pp. 1851-1858
    • Attele, A.S.1    Zhou, Y.P.2    Xie, J.T.3    Wu, J.A.4    Zhang, L.5    Dey, L.6    Pugh, W.7    Rue, P.A.8    Polonsky, K.S.9    Yuan, C.S.10
  • 55
    • 0012397405 scopus 로고    scopus 로고
    • Effects of American ginseng berry extract on blood glucose levels in ob/ob mice
    • Xie JT, Aung HH, Wu JA, Attele AS, Yuan CS. Effects of American ginseng berry extract on blood glucose levels in ob/ob mice. Am J Chin Med 2002, 30(2-3):187-194.
    • (2002) Am J Chin Med , vol.30 , Issue.2-3 , pp. 187-194
    • Xie, J.T.1    Aung, H.H.2    Wu, J.A.3    Attele, A.S.4    Yuan, C.S.5
  • 56
    • 0036250280 scopus 로고    scopus 로고
    • Ginseng berry reduces blood glucose and body weight in db/db mice
    • 10.1078/0944-7113-00106, 12046868
    • Xie JT, Zhou Y-P, Dey L, Attele A, Wu J, Gu M, Polonnsky K, Yuan C. Ginseng berry reduces blood glucose and body weight in db/db mice. Phytomedicine 2002, 9:254-258. 10.1078/0944-7113-00106, 12046868.
    • (2002) Phytomedicine , vol.9 , pp. 254-258
    • Xie, J.T.1    Zhou, Y.-P.2    Dey, L.3    Attele, A.4    Wu, J.5    Gu, M.6    Polonnsky, K.7    Yuan, C.8
  • 57
    • 0024368051 scopus 로고
    • The action of adaptogenic plant preparations in experimental alloxan diabetes
    • Molokovskii DS, Davydov VV, Tiulenev VV. The action of adaptogenic plant preparations in experimental alloxan diabetes. Probl Endokrinol (Mosk) 1989, 35(6):82-87.
    • (1989) Probl Endokrinol (Mosk) , vol.35 , Issue.6 , pp. 82-87
    • Molokovskii, D.S.1    Davydov, V.V.2    Tiulenev, V.V.3
  • 58
    • 0034117424 scopus 로고    scopus 로고
    • Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro
    • 10.1021/jf9904517, 10725162
    • Broadhurst CL, Polansky MM, Anderson RA. Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro. J Agric Food Chem 2000, 48(3):849-852. 10.1021/jf9904517, 10725162.
    • (2000) J Agric Food Chem , vol.48 , Issue.3 , pp. 849-852
    • Broadhurst, C.L.1    Polansky, M.M.2    Anderson, R.A.3
  • 59
    • 0025494755 scopus 로고
    • Efficacy of ginseng drugs in experimental insulin-dependent diabetes and toxic hepatitis
    • Davydov VV, Molokovskii DS, Limarenko A. Efficacy of ginseng drugs in experimental insulin-dependent diabetes and toxic hepatitis. Patol Fiziol Eksp Ter 1990, (5):49-52.
    • (1990) Patol Fiziol Eksp Ter , Issue.5 , pp. 49-52
    • Davydov, V.V.1    Molokovskii, D.S.2    Limarenko, A.3
  • 60
    • 24744467359 scopus 로고    scopus 로고
    • Antihyperglycemic effects of total ginsenosides from leaves and stem of Panax ginseng
    • 10.1111/j.1745-7254.2005.00156.x, 16115378
    • Xie JT, Wang CZ, Wang AB, Wu J, Basila D, Yuan CS. Antihyperglycemic effects of total ginsenosides from leaves and stem of Panax ginseng. Acta Pharmacol Sin 2005, 26(9):1104-1110. 10.1111/j.1745-7254.2005.00156.x, 16115378.
    • (2005) Acta Pharmacol Sin , vol.26 , Issue.9 , pp. 1104-1110
    • Xie, J.T.1    Wang, C.Z.2    Wang, A.B.3    Wu, J.4    Basila, D.5    Yuan, C.S.6
  • 61
    • 35348876798 scopus 로고    scopus 로고
    • American ginseng berry juice intake reduces blood glucose and body weight in ob/ob mice
    • 10.1111/j.1750-3841.2007.00481.x, 2658891, 17995625
    • Xie JTWC, Ni M, Wu JA, Mehendale SR, Aung HH, Yuan CS. American ginseng berry juice intake reduces blood glucose and body weight in ob/ob mice. J Food Sci 2007, 72(8):S590-S594. 10.1111/j.1750-3841.2007.00481.x, 2658891, 17995625.
    • (2007) J Food Sci , vol.72 , Issue.8
    • Xie, J.T.W.C.1    Ni, M.2    Wu, J.A.3    Mehendale, S.R.4    Aung, H.H.5    Yuan, C.S.6
  • 62
    • 15944420098 scopus 로고    scopus 로고
    • Development of the novel anti-cancer immunotherapy for human prostate cancer: In vivo characterization of an immunotropic and anti-cancer activities of the new polysaccharide from the leaves of Panax ginseng C.A. Meyer
    • Park HSKT, Moon DG, Kim JJ, Cheon J. Development of the novel anti-cancer immunotherapy for human prostate cancer: In vivo characterization of an immunotropic and anti-cancer activities of the new polysaccharide from the leaves of Panax ginseng C.A. Meyer. Eur Urol Suppl 3 2004, (2):365-366.
    • (2004) Eur Urol Suppl 3 , Issue.2 , pp. 365-366
    • Park, H.S.K.T.1    Moon, D.G.2    Kim, J.J.3    Cheon, J.4
  • 63
    • 42449099302 scopus 로고    scopus 로고
    • Selective killing of cancer cells by leaf extract of Ashwagandha: Components, activity and pathway analyses
    • Widodo N, Takagi Y, Shrestha BG, Ishii T, Kaul SC, Wadhwa R. Selective killing of cancer cells by leaf extract of Ashwagandha: Components, activity and pathway analyses. Cancer Lett 2008, 262:37-47.
    • (2008) Cancer Lett , vol.262 , pp. 37-47
    • Widodo, N.1    Takagi, Y.2    Shrestha, B.G.3    Ishii, T.4    Kaul, S.C.5    Wadhwa, R.6
  • 64
    • 36849093425 scopus 로고    scopus 로고
    • Protective effects of total saponins from stem and leaf of Panax ginseng against cyclophosphamide-induced genotoxicity and apoptosis in mouse bone marrow cells and peripheral lymphocyte cells
    • 10.1016/j.fct.2007.08.025, 17904265
    • Zhang QH, Wu CF, Duan L, Yang JY. Protective effects of total saponins from stem and leaf of Panax ginseng against cyclophosphamide-induced genotoxicity and apoptosis in mouse bone marrow cells and peripheral lymphocyte cells. Food Chem Toxicol 2008, 46(1):293-302. 10.1016/j.fct.2007.08.025, 17904265.
    • (2008) Food Chem Toxicol , vol.46 , Issue.1 , pp. 293-302
    • Zhang, Q.H.1    Wu, C.F.2    Duan, L.3    Yang, J.Y.4
  • 65
    • 38849101477 scopus 로고    scopus 로고
    • Characterizing the mechanism for ginsenoside-induced cytotoxicity in cultured leukemia (THP-1) cells
    • 10.1139/Y07-099, 18066119
    • Kitts DD, Popovich DG, Hu C. Characterizing the mechanism for ginsenoside-induced cytotoxicity in cultured leukemia (THP-1) cells. Can J Physiol Pharmacol 2007, 85(11):1173-1183. 10.1139/Y07-099, 18066119.
    • (2007) Can J Physiol Pharmacol , vol.85 , Issue.11 , pp. 1173-1183
    • Kitts, D.D.1    Popovich, D.G.2    Hu, C.3
  • 66
    • 0033994838 scopus 로고    scopus 로고
    • Antioxidant properties of a North American ginseng extract
    • 10.1023/A:1007078414639, 10724326
    • Kitts DD, Wijewickreme AN, Hu C. Antioxidant properties of a North American ginseng extract. Mol Cell Biochem 2000, 203:1-10. 10.1023/A:1007078414639, 10724326.
    • (2000) Mol Cell Biochem , vol.203 , pp. 1-10
    • Kitts, D.D.1    Wijewickreme, A.N.2    Hu, C.3
  • 67
    • 0035064619 scopus 로고    scopus 로고
    • Six new dammarane-type triterpene saponins from the leaves of Panax ginseng
    • 10.1248/cpb.49.442, 11310671
    • Dou DQ, Chen YJ, Liang LH, Pang FG, Shimizu N, Takeda T. Six new dammarane-type triterpene saponins from the leaves of Panax ginseng. Chem Pharm Bull (Tokyo) 2001, 49(4):442-446. 10.1248/cpb.49.442, 11310671.
    • (2001) Chem Pharm Bull (Tokyo) , vol.49 , Issue.4 , pp. 442-446
    • Dou, D.Q.1    Chen, Y.J.2    Liang, L.H.3    Pang, F.G.4    Shimizu, N.5    Takeda, T.6
  • 68
    • 16244398405 scopus 로고    scopus 로고
    • Effects of wild ginseng (Panax ginseng C.A. Meyer) leaves on lipid peroxidation levels and antioxidant enzyme activities in streptozotocin diabetic rats
    • 10.1016/j.jep.2004.12.030, 15814255
    • Jung CH, Seog HM, Choi IW, Choi HD, Cho HY. Effects of wild ginseng (Panax ginseng C.A. Meyer) leaves on lipid peroxidation levels and antioxidant enzyme activities in streptozotocin diabetic rats. J Ethnopharmacol 2005, 98(3):245-250. 10.1016/j.jep.2004.12.030, 15814255.
    • (2005) J Ethnopharmacol , vol.98 , Issue.3 , pp. 245-250
    • Jung, C.H.1    Seog, H.M.2    Choi, I.W.3    Choi, H.D.4    Cho, H.Y.5
  • 69
    • 15944426424 scopus 로고    scopus 로고
    • Antioxidant activities of cultivated and wild Korean ginseng leaves
    • Jung C-HS, H-M Choi I-W, Cho H-Y. Antioxidant activities of cultivated and wild Korean ginseng leaves. Food Chemistry 2005, 92:535-540.
    • (2005) Food Chemistry , vol.92 , pp. 535-540
    • Jung, C.-H.S.1    H-M Choi, I.-W.2    Cho, H.-Y.3
  • 70
    • 28844453664 scopus 로고    scopus 로고
    • Antioxidant properties of various solvent extracts from wild ginseng leaves
    • Jung C-HS, H-M Choi I-W, Park M-W, Cho H-Y. Antioxidant properties of various solvent extracts from wild ginseng leaves. LWT 2006, 39:266-274.
    • (2006) LWT , vol.39 , pp. 266-274
    • Jung, C.-H.S.1    H-M Choi, I.-W.2    Park, M.-W.3    Cho, H.-Y.4
  • 71
    • 0026919831 scopus 로고
    • Influences of ginsenosides Rb1, Rb2, and Rb3 on electric and contractile activities of normal and damaged cultured myocardiocytes
    • Jiang Y, Zhong GG, Chen L, Ma XY. Influences of ginsenosides Rb1, Rb2, and Rb3 on electric and contractile activities of normal and damaged cultured myocardiocytes. Zhongguo Yao Li Xue Bao 1992, 13(5):403-406.
    • (1992) Zhongguo Yao Li Xue Bao , vol.13 , Issue.5 , pp. 403-406
    • Jiang, Y.1    Zhong, G.G.2    Chen, L.3    Ma, X.Y.4
  • 72
    • 0020776486 scopus 로고
    • Studies on the anti-fatigue effect of the saponins of stems and leaves of panax ginseng (SSLG)
    • Wang B, Cui J, Liu A, Wu S. Studies on the anti-fatigue effect of the saponins of stems and leaves of panax ginseng (SSLG). J Tradit Chin Med 1983, 3:89-94.
    • (1983) J Tradit Chin Med , vol.3 , pp. 89-94
    • Wang, B.1    Cui, J.2    Liu, A.3    Wu, S.4
  • 73
    • 0019120313 scopus 로고
    • Antidiuretic effect of ginsenosides of the stems and leaves of Panax ginseng
    • Wang B, Cui J, Liu A. Antidiuretic effect of ginsenosides of the stems and leaves of Panax ginseng. Acta Pharmacol Sin 1980, 1:126-130.
    • (1980) Acta Pharmacol Sin , vol.1 , pp. 126-130
    • Wang, B.1    Cui, J.2    Liu, A.3
  • 74
    • 0033117956 scopus 로고    scopus 로고
    • Clinical study on retarding aging effect of tongbu recipe to traditional Chinese medicine
    • Zhou L, Hao R, Jiang L. Clinical study on retarding aging effect of tongbu recipe to traditional Chinese medicine. Zhongguo Zhong Xi Yi Jie He Za Zhi 1999, 19:218-220.
    • (1999) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.19 , pp. 218-220
    • Zhou, L.1    Hao, R.2    Jiang, L.3
  • 75
    • 0027830515 scopus 로고
    • Inductive differentiation effect of ginsenosides on human acute nonlymphocytic leukemic cells in 58 patients
    • Yi RL, Li W, Hao XZ. Inductive differentiation effect of ginsenosides on human acute nonlymphocytic leukemic cells in 58 patients. Zhongguo Zhong Xi Yi Jie He Za Zhi 1993, 13:722-724.
    • (1993) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.13 , pp. 722-724
    • Yi, R.L.1    Li, W.2    Hao, X.Z.3
  • 76
    • 0034964205 scopus 로고    scopus 로고
    • Adaptogenic activity of a novel, withanolide-free aqueous fraction from the roots of Withania somnifera Dun
    • 10.1002/ptr.858, 11406854
    • Singh B, Saxena AK, Chandan BK, Gupta DK, Bhutani KK, Anand KK. Adaptogenic activity of a novel, withanolide-free aqueous fraction from the roots of Withania somnifera Dun. Phytother Res 2001, 15:311-318. 10.1002/ptr.858, 11406854.
    • (2001) Phytother Res , vol.15 , pp. 311-318
    • Singh, B.1    Saxena, A.K.2    Chandan, B.K.3    Gupta, D.K.4    Bhutani, K.K.5    Anand, K.K.6
  • 77
    • 0033555737 scopus 로고    scopus 로고
    • Unsafe and potentially safe herbal theraties
    • Klepser TB, Klepser ME. Unsafe and potentially safe herbal theraties. Am J Health Sys Pharm 1999, 56:125-138.
    • (1999) Am J Health Sys Pharm , vol.56 , pp. 125-138
    • Klepser, T.B.1    Klepser, M.E.2
  • 79
    • 0036283370 scopus 로고    scopus 로고
    • Panax ginseng : a systematic review of adverse effects and drug interactions
    • 10.2165/00002018-200225050-00003, 12020172
    • Coon JT, Ernst E. Panax ginseng : a systematic review of adverse effects and drug interactions. Drug Saf 2002, 25:323-344. 10.2165/00002018-200225050-00003, 12020172.
    • (2002) Drug Saf , vol.25 , pp. 323-344
    • Coon, J.T.1    Ernst, E.2
  • 80
    • 0018743257 scopus 로고
    • Ginseng abuse syndrome. Problems with the panacea
    • 10.1001/jama.241.15.1614, 430716
    • Siegel RK. Ginseng abuse syndrome. Problems with the panacea. JAMA 1979, 241(15):1614-1615. 10.1001/jama.241.15.1614, 430716.
    • (1979) JAMA , vol.241 , Issue.15 , pp. 1614-1615
    • Siegel, R.K.1
  • 81
    • 0034255413 scopus 로고    scopus 로고
    • The aphrodisiac and adaptogenic properties of ginseng
    • Nocerino E, Amato M, Izzo A. The aphrodisiac and adaptogenic properties of ginseng. Fitoterapia 2002, 71:S1-S5.
    • (2002) Fitoterapia , vol.71
    • Nocerino, E.1    Amato, M.2    Izzo, A.3
  • 83
    • 0034945280 scopus 로고    scopus 로고
    • Herbal Medicines and perioperative care
    • 10.1001/jama.286.2.208, 11448284
    • Ang-Lee MKM, J Yuan C-S. Herbal Medicines and perioperative care. JAMA 2001, 286:208-216. 10.1001/jama.286.2.208, 11448284.
    • (2001) JAMA , vol.286 , pp. 208-216
    • Ang-Lee, M.K.M.1    J Yuan, C.-S.2
  • 84
    • 0015894134 scopus 로고
    • Pharmacological studies of Panax Ginseng leaves
    • Saito H, Morita M, Takagi K. Pharmacological studies of Panax Ginseng leaves. Jpn J Pharmacol 1973, 23(1):43-56.
    • (1973) Jpn J Pharmacol , vol.23 , Issue.1 , pp. 43-56
    • Saito, H.1    Morita, M.2    Takagi, K.3


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