siRNA-mediated knockdown against CDCA1 and KNTC2, both frequently overexpressed in colorectal and gastric cancers, suppresses cell proliferation and induces apoptosis

Biochemical and Biophysical Research Communications

Volumn 390, Issue 4, 2009, Pages 1235-1240

  Kaneko, Naoyuki ^a   Miura, Koh ^a   Gu, Zhaodi ^a   Karasawa, Hideaki ^a   Ohnuma, Shinobu ^a   Sasaki, Hiroyuki ^a   Tsukamoto, Nobukazu ^a   Yokoyama, Satoru ^a   Yamamura, Akihiro ^a   Nagase, Hiroki ^b   Shibata, Chikashi ^a   Sasaki, Iwao ^a   Horii, Akira ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; CDCA1; Colorectal cancer; Gastric cancer; Kinetochore; KNTC2; Ndc80; RNAi; SPC24; SPC25; Spindle checkpoint

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CELL CYCLE PROTEIN; CELL DIVISION CYCLE ASSOCIATED 1; KINETOCHORE ASSOCIATED 2; NDC80 COMPLEX; SMALL INTERFERING RNA; SPINDLE POLE BODY COMPONENT 24 PROTEIN; SPINDLE POLE BODY COMPONENT 25 PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL GROWTH; CELL PROLIFERATION; COLORECTAL CANCER; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME REPRESSION; FLOW CYTOMETRY; GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; MUCOSA; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER;

APOPTOSIS; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; COLORECTAL NEOPLASMS; GENE KNOCKDOWN TECHNIQUES; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; NUCLEAR PROTEINS; RNA, SMALL INTERFERING; STOMACH NEOPLASMS;

EID: 70450278741     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.10.127     Document Type: Article

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