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Volumn 284, Issue 47, 2009, Pages 32384-32394
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CK1α plays a central role in mediating MDM2 control of p53 and E2F-1 protein stability
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Author keywords
[No Author keywords available]
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Indexed keywords
APOPTOSIS;
APOPTOTIC SIGNALING;
CASEIN KINASE;
CO-IMMUNOPRECIPITATIONS;
DNA VIRUS;
GENETIC PATHWAYS;
GROWTH ARREST;
KINASE INHIBITORS;
MULTI-PROTEIN COMPLEX;
NEGATIVE REGULATORS;
P53 PROTEIN;
PHARMACOLOGICAL PROPERTIES;
PROTEIN LEVEL;
PROTEIN STABILITY;
SMALL INTERFERING RNA;
SMALL MOLECULE INHIBITOR;
STABLE COMPLEXES;
STEADY-STATE LEVEL;
TRANSFORMING GROWTH FACTORS;
TUMOR SUPPRESSORS;
UBIQUITIN LIGASES;
UBIQUITINATION;
CELL DEATH;
CLONING;
ENZYMES;
NUCLEIC ACIDS;
RNA;
TRANSCRIPTION FACTORS;
COBALT COMPOUNDS;
CASEIN KINASE I;
PROTEIN MDM2;
PROTEIN P53;
SMALL INTERFERING RNA;
TRANSCRIPTION FACTOR E2F1;
4 (4 (2,3 DIHYDROBENZO(1,4)DIOXIN 6 YL) 5 PYRIDIN 2 YL 1H IMIDAZOL 2 YL)BENZAMIDE;
4-(4-(2,3-DIHYDROBENZO(1,4)DIOXIN-6-YL)-5-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE;
BENZAMIDE DERIVATIVE;
IMIDAZOLE DERIVATIVE;
ISOPROTEIN;
MDM2 PROTEIN, HUMAN;
NUTLIN 1;
PIPERAZINE DERIVATIVE;
TP53 PROTEIN, HUMAN;
APOPTOSIS;
ARTICLE;
CHROMATIN IMMUNOPRECIPITATION;
CONTROLLED STUDY;
GENE EXPRESSION REGULATION;
HUMAN;
HUMAN CELL;
NUCLEOTIDE SEQUENCE;
PRIORITY JOURNAL;
PROTEIN DEPLETION;
PROTEIN PROTEIN INTERACTION;
PROTEIN STABILITY;
SIGNAL TRANSDUCTION;
STEADY STATE;
BIOLOGICAL MODEL;
CELL CYCLE;
METABOLISM;
PHOSPHORYLATION;
PHYSIOLOGY;
TUMOR CELL LINE;
DNA VIRUSES;
MURINAE;
APOPTOSIS;
BENZAMIDES;
CASEIN KINASE I;
CELL CYCLE;
CELL LINE, TUMOR;
E2F1 TRANSCRIPTION FACTOR;
GENE EXPRESSION REGULATION, NEOPLASTIC;
HUMANS;
IMIDAZOLES;
MODELS, BIOLOGICAL;
PHOSPHORYLATION;
PIPERAZINES;
PROTEIN ISOFORMS;
PROTO-ONCOGENE PROTEINS C-MDM2;
RNA, SMALL INTERFERING;
TUMOR SUPPRESSOR PROTEIN P53;
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EID: 70450260576
PISSN: 00219258
EISSN: 1083351X
Source Type: Journal
DOI: 10.1074/jbc.M109.052647 Document Type: Article |
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Times cited : (86)
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References (26)
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