Characterization of nuclear localization signal in the N terminus of CUL4B and its essential role in cyclin E degradation and cell cycle progression

Journal of Biological Chemistry

Volumn 284, Issue 48, 2009, Pages 33320-33332

  Zou, Yongxin ^a   Mi, Jun ^a   Cui, Jinpeng ^a   Lu, Defen ^a   Zhang, Xiyu ^a   Guo, Chenhong ^a   Gao, Guimin ^a   Liu, Qiji ^a   Chen, Bingxi ^a   Shao, Changshun ^a,b   Gong, Yaoqin ^a  

^a Shandong University   (China)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE REGULATION; CELL-CYCLE PROGRESSION; CELLULAR PROCESS; CULLINS; CYCLIN E; DNA REPAIR; GENETIC STUDIES; GERM LINE; HEPATOCELLULAR; IN-CELL; MENTAL RETARDATION; NORMAL FUNCTION; NUCLEAR LOCALIZATION; NUCLEAR LOCALIZATION SIGNAL; RNA INTERFERENCE; S-PHASE; SCAFFOLD PROTEIN; UBIQUITIN LIGASES; UBIQUITINATION;

AMINES; AMINO ACIDS; ENZYMES; NUCLEIC ACIDS; ORGANIC ACIDS; PROTEINS; RNA;

CELL PROLIFERATION;

CYCLIN E; KARYOPHERIN ALPHA; KARYOPHERIN ALPHA1; KARYOPHERIN ALPHA3; KARYOPHERIN ALPHA5; PROTEIN CUL4B; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; GENE MAPPING; GENE SILENCING; HUMAN; HUMAN CELL; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; RNA INTERFERENCE; SITE DIRECTED MUTAGENESIS; UBIQUITINATION;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE; CELL LINE; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CULLIN PROTEINS; CYCLIN E; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR LOCALIZATION SIGNALS; PROTEIN BINDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 70450225328     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.050427     Document Type: Article

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