Novel approaches for mechanistic understanding and predicting preeclampsia

Journal of Reproductive Immunology

Volumn 83, Issue 1-2, 2009, Pages 134-138

  Kalkunte, Satyan ^a   Lai, Zhongbin ^a   Norris, Wendy E ^a   Pietras, Linda A ^a   Tewari, Neetu ^a   Boij, Roland ^a   Neubeck, Stefan ^b   Markert, Udo R ^b   Sharma, Surendra ^a  

^a BROWN UNIVERSITY   (United States)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Biological assay; Preeclampsia; Pregnancy serum; Proteomics

Indexed keywords

CYTOKINE;

ANTIPHOSPHOLIPID SYNDROME; APOPTOSIS; BIOCHEMISTRY; CLINICAL FEATURE; COMPLEMENT ACTIVATION; CYTOTOXICITY; DISEASE COURSE; DISEASE MARKER; EPITHELIUM CELL; FIRST TRIMESTER PREGNANCY; GESTATION PERIOD; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INTRAUTERINE GROWTH RETARDATION; MOTHER FETUS RELATIONSHIP; NONHUMAN; ONSET AGE; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PLACENTA DISORDER; PLACENTA PERFUSION; PREDICTION; PREECLAMPSIA; PREMATURE FETUS MEMBRANE RUPTURE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; REVIEW; SYMPTOM; SYSTEMIC DISEASE; THIRD TRIMESTER PREGNANCY; TROPHOBLAST;

ANIMALS; BIOLOGICAL MARKERS; FEMALE; HUMANS; PLACENTATION; PRE-ECLAMPSIA; PREGNANCY; PROGNOSIS; PROTEOMICS; SEROLOGIC TESTS;

EID: 70449713288     PISSN: 01650378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jri.2009.08.006     Document Type: Review

References (46)

1. Abrams B., and Pickett K.E. Maternal nutrition. In: Creasy R.K., and Resnik R. (Eds). Maternal-Fetal Medicine. 4th edn. (1999), W.B. Saunders Company, Philadelphia, PA 122-131
2. Allaire A.D., Ballenger K.A., Wells S.R., McMohan M.J., and Lessey B.A. Placental apoptosis in preeclampsia. Obsetet. Gynecol. 96 (2000) 271-276
3. Ashkar A.A., Di Santo J.P., and Croy B.A. Interferon γ contributes to initiation of uterine vascular modification, decidual integrity, and uterine natural killer cell maturation during normal murine pregnancy. J. Exp. Med. 192 (2000) 259-269
4. Baumann M.U., Bersinger N.A., and Surbek D.V. Serum markers for predicting pre-eclampsia. Mol. Aspects Med. 28 (2007) 227-244
5. Bulla R., Villa A., Bossi F., Cassetti A., Radillo O., Spessotto P., De seta F., Guaschino S., and Tedesco F. VE-cadherin is a critical molecule for trophoblast-endothelial cell interaction in decidual spiral arteries. Exp. Cell Res. 303 (2005) 101-113
6. Crocker I.P., Cooper S., Ong S.C., and Baker P.N. Altered cell kinetics in cultured placental villous explants in pregnancies complicated by preeclampsia and intra-uterine growth restriction. J. Pathol. 204 (2004) 11-18
7. Dekker G., and Sibai B. Primary, secondary and tertiary prevention of pre-eclampsia. Lancet 357 (2001) 209-215
8. Gagon A., and Wilson R.D. Obstetrical complications associated with abnormal maternal serum marker analytes. J. Obstet. Gynaecol. Can. 30 (2008) 918-932
9. Gilbert J.S., Ryan M.J., LaMarca B.B., Sedeek M., Murphy S.R., and Granger J.P. Pathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunction. Am. J. Physiol. Heart Circ. Physiol. 294 (2008) 541-550
10. Girardi G., Redecha P., and Salmon J.E. Heparin prevents antiphospholipid antibody-induced fetal loss by inhibiting complement activation. Nat. Med. 10 (2004) 1222-1226
11. Girardi G., Yarilin D., Thurman J.M., Holers V.M., and Salmon J.E. Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction. J. Exp. Med. 203 (2006) 2165-2175
12. Haeger M., Unander M., Norder-Hansson B., Tylman M., and Bengtsson A. Complement, neutrophil, and macrophage activation in women with severe preeclampsia and the syndrome of hemolysis, elevated liver enzymes, and low platelet count. Obstet. Gynecol. 79 (1992) 19-26
13. Hanna J., Goldman-Wohl D., Hamani Y., Avraham I., Greenfield C., Natanson-Yaron S., Prus D., Cohen-Daniel L., Arnon T.I., Manaster I., Gazit R., Yutkin V., Benharroch D., Porgador A., Keshet E., Yagel S., and Mandelboim O. Decidual NK cells regulate key developmental processes at the human fetal-maternal interface. Nat. Med. 12 (2006) 1065-1074
14. Heazell A.E.P., and Crocker I.P. Live and let die-regulation of villous trophoblast apoptosis in normal and abnormal pregnancies. Placenta 29 (2008) 772-783
15. Heitner J.C., Koy C., Kreutzer M., Gerber B., Reimer T., and Glocker M.O. Differentiation of HELLP patients from healthy pregnant women by proteome analysis-on the way towards a clinical marker set. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 840 (2006) 10-19
16. Hung T.H., Skepper J.N., Charnock-Jones S.D., and Burton G.J. Hypoxia reoxygenation. A potent inducer of apoptotic changes in the human placenta and possible etiological factor in preeclampsia. Circ. Res. 90 (2002) 1274-1281
17. Issaq H.J., Veenstra T.D., Conrads T.P., and Felschow D. The SELDI-TOF MS approach to proteomics: protein profiling and biomarker identification. Biochem. Biophys. Res. Commun. 292 (2002) 587-592
18. Jonsson Y., Rubèr M., Matthiesen L., Berg G., Nieminen K., Sharma S., Ernerudh J., and Ekerfelt C. Cytokine mapping of sera from women with preeclampsia and normal pregnancies. J. Reprod. Immunol. 70 (2006) 83-91
19. Kalkunte S., Chichester C.O., Gotsch F., Sentman C.L., Romero R., and Sharma S. Evolution of non-cytotoxic uterine natural killer cells. Am. J. Reprod. Immunol. 59 (2008) 425-432
20. Kalkunte S., Lai Z., Tewari N., Chichester C., Romero R., Padbury J., and Sharma S. In vitro and in vivo evidence for lack of endovascular remodeling by third trimester trophoblasts. Placenta 29 (2008) 871-878
21. Kalkunte S., Mselle T.F., Norris W.E., Wira C.R., Sentman C.L., and Sharma S. VEGF C facilitates immune tolerance and endovascular activity of human uterine NK cells at the maternal-fetal interface. J. Immunol. 182 (2009) 4085-4092
22. Khong T.Y., De Wolf F., Robertson W.B., and Brosens I. Inadequate maternal vascular response to placentation in pregnancies complicated by pre-eclampsia and by small-for-gestational age infants. Br. J. Obstet. Gynecol. 93 (1986) 1049-1059
23. Kim Y.M., Bujold E., Chaiworapongsa T., Gomez R., Yoon B.H., Thaler H.T., Rotmensch S., and Romero R. Failure of physiologic transformation of the spiral arteries in patients with preterm labor and intact membranes. Am. J. Obstet. Gynecol. 189 (2003) 1063-1069
24. Levine R.J., Maynard S.E., Qian C., Lim K.H., England L.J., Yu K.F., Schisterman E.F., Thadhani R., Sachs B.P., Epstein F.H., Sibai B.M., Sukhatme V.P., and Karumanchi S.A. Circulating angiogenic factors and the risk of preeclampsia. N. Engl. J. Med. 350 (2004) 672-683
25. Levy R., Smith S.D., Yusuf K., Huettner P.C., Kraus F.T., Sadovsky Y., and Nelson D.M. Trophoblasts apoptosis from pregnancies complicated by fetal growth restriction is associated with enhanced p53 expression. Am. J. Obstet. Gynecol. 186 (2002) 1056-1061
26. Lynch A.M., Murphy J.R., Byers T., Gibbs R.S., Neville M.C., Giclas P.C., Salmon J.E., and Holers V.M. Alternative complement pathway activation fragment Bb in early pregnancy as a predictor of preeclampsia. Am. J. Obstet. Gynecol. 198 385 (2008) e1-e9
27. Matzuk M.M., Burns K.H., Viveiros M.M., and Eppig J.J. Intercellular communication in the mammalian ovary: oocytes carry the conversation. Science 296 (2002) 2178-2180
28. Medawar P.B. Some immunological and endocrinological problems raised by the evolution of viviparity in vertebrates. Symp. Soc. Exp. Biol. 7 (1953) 320-338
29. Moffett A., and Hiby S.E. How does the maternal immune system contribute to the development of pre-eclampsia?. Placenta 28 (2007) S51-S56
30. Mohaupt M. Molecular aspects of preeclampsia. Mol. Aspects Med. 28 (2007) 169-191
31. Murphy S.P., Fast L.D., Hanna N.N., and Sharma S. Uterine NK cells mediate inflammation-induced fetal demise in IL-10-null mice. J. Immunol. 175 (2005) 4084-4090
32. Murphy S.P., Hanna N.N., Fast L.D., Shaw S., Berg G., Padbury J.F., Romero R., and Sharma S. Evidence for participation of uterine natural killer cells in the mechanisms responsible for spontaneous preterm labor and delivery. Am. J. Obstet. Gynecol. 200 (2009) 308, e1-308.e9
33. Mutter W.P., and Karumanchi S.A. Molecular mechanisms of preeclampsia. Microvasc. Res. 75 (2008) 1-8
34. Naicker T., Khedun S.M., Moodley J., and Pijnenborg R. Quantitative analysis of trophoblast invasion in preeclampsia. Acta Obstet. Gynecol. Scand. 82 (2003) 722-729
35. Nevo O., Soleymanlou N., Wu Y., Xu J., Kingdom J., Many A., Zamudio S., and Caniggia I. Increased expression of sFlt-1 in in vivo and in vitro models of human placental hypoxia is mediated by HIF-1. Am. J. Physiol. Regul. Integr. Comp. Physiol. 355 (2006) 992-1005
36. Paria B.C., Reese J., Das S.K., and Dey S.K. Deciphering the cross-talk of implantation: advances and challenges. Science 296 (2002) 2185-2188
37. Rampersad R., Barton A., Sadovsky Y., and Nelson D.M. The C5b-9 membrane attack complex of complement activation localizes to villous trophoblasts injury in vivo and modulates human trophoblast function in vitro. Placenta 29 (2008) 855-861
38. Redman C.W.G., and Sargent I.L. Placental debris, oxidative stress and preeclampsia. Placenta 21 (2000) 597-602
39. Report of the national high blood pressure education program working group on high blood pressure in pregnancy, 2000. Am. J. Obstet. Gynecol. 183, S1-S22.
40. Roberts J.M., and Hubel C.A. Is oxidative stress the link in the two-stage model of preeclampsia. Lancet 354 (1999) 788-789
41. Sibai B., Dekker G., and Kupferminc M. Pre-eclampsia. Lancet 365 (2005) 785-799
42. Tedesco F., Narchi G., Radillo O., Meri S., Ferrone S., and Betterle C. Susceptibility of human trophoblast to killing by human complement and the role of complement regulatory proteins. J. Immunol. 151 (1993) 1562-1570
43. Thaxton J., Romero R., and Sharma S. TLR-9 activation coupled to IL-10 deficiency induces adverse pregnancy outcomes. J. Immunol. 183 (2009) 1144-1154
44. Vatten L.J., and Skjaerven R. Is pre-eclampsia more than one disease?. Br. J. Obstet. Gynecol. 111 (2004) 298-302
45. Watanabe H., Hamada H., Yamada N., Sohda S., Yamakawa-Kobayashi K., Yoshikawa H., and Arinami T. Proteome analysis reveals elevated serum levels of clusterin in patients with preeclampsia. Proteomics 4 (2004) 537-543
46. Zhau Y., Fisher S.J., Janatpor M., Genbacev O., Dejana E., Wheelock M., and Damsky C.H. Human cytotrophoblasts adopt a vascular as they differentiate. A strategy for successful endovascular invasion. J. Clin. Invest. 99 (1997) 2139-2151