In Vitro and In Vivo Evidence for Lack of Endovascular Remodeling by Third Trimester Trophoblasts

Placenta

Volumn 29, Issue 10, 2008, Pages 871-878

  Kalkunte, S ^a   Lai, Z ^a   Tewari, N ^a   Chichester, C ^b   Romero, R ^c   Padbury, J ^a   Sharma, S ^a  

^a WOMEN AND INFANTS HOSPITAL   (United States)

^b UNIVERSITY OF RHODE ISLAND   (United States)

^c EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Angiogenesis; Capillary tube formation; E cadherin; Endothelial cells; Three dimensional co culture system; Trophoblast invasion; VEGF C and VEGF R2

Indexed keywords

MATRIGEL; UVOMORULIN; VASCULOTROPIN; VASCULOTROPIN C; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ARTICLE; BLOOD SAMPLING; CAPILLARY PROLIFERATION; CELL CULTURE; CELL FUNCTION; CELL IMMORTALIZATION; CELL INTERACTION; CELL INVASION; CELL MATURATION; CELL MIGRATION; CELL STRUCTURE; CELL SYNCHRONIZATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; FEMALE; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR MIMICRY; PLACENTA VILLUS; PREGNANCY OUTCOME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; THIRD TRIMESTER PREGNANCY; TROPHOBLAST;

ANTIGENS, CD; ARTERIES; CADHERINS; CELL LINE; COCULTURE TECHNIQUES; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; PLACENTA; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PREGNANCY TRIMESTER, THIRD; RECEPTORS, CELL SURFACE; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; TROPHOBLASTS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR C; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 51249104241     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.placenta.2008.07.009     Document Type: Article

References (35)

1. Georgiades P., Ferguson-Smith A.C., and Burton G.J. Comparative developmental anatomy of the murine and human definitive placentae. Placenta 23 (2002) 3-19
2. Pijnenborg R., Bland J.M., Robertson W.B., and Brosens I. Uteroplacental arterial changes related to interstitial trophoblast migration in early human pregnancy. Placenta 4 (1983) 397-413
3. Naicker T., Khedun S.M., Moodley J., and Pijnenborg R. Quantitative analysis of trophoblast invasion in preeclampsia. Acta Obstet Gynecol Scand 82 (2003) 722-729
4. Espinoza J., Romero R., Mee Kim Y., Kusanovic J.P., Hassan S., Erez O., et al. Normal and abnormal transformation of the spiral arteries during pregnancy. J Perinat Med 34 (2006) 447-458
5. Kim Y.M., Bujold E., Chaiworapongsa T., Gomez R., Yoon B.H., Thaler H.T., et al. Failure of physiologic transformation of the spiral arteries in patients with preterm labor and intact membranes. Am J Obstet Gynecol 189 (2003) 1063-1069
6. Aplin J., Charlton S., and Ayad S. An immunohistochemical study of human endometrial extracellular matrix during the menstrual cycle and first trimester of pregnancy. Cell Tissue Res 253 (1988) 231-240
7. Kham E.P., Gardner L., Loke Y.W., and King A. The role of trophoblasts in the physiological change in decidual spiral arteries. Hum Reprod 14 (1999) 2131-2138
8. Gilbert J.S., Ryan M.J., LaMarca B.B., Sedeek M., Murphy S.R., and Granger J.P. Pathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunction. Am J Physiol Heart Circ Physiol 294 (2008) 541-550
9. Hanna N., Hanna I., Hleb M., Wagner E., Dougherty J., Balkundi D., et al. Gestational age-dependent expression of IL-10 and its receptor in human placental tissues and isolated cytotrophoblasts. J Immunol 164 (2000) 5721-5728
10. Renaud S.J., Postovit L.M., Macdonald-Goodfellow S.K., McDonald G.T., Caldwell J.D., and Graham C.H. Activated macrophages inhibit human cytotrophoblast invasiveness in vitro. Biol Reprod 73 (2005) 237-243
11. Aldo P.B., Krikun G., Visintin I., Lockwood C., Romero R., and Mor G. A novel three-dimensional in vitro system to study trophoblast-endothelium cell interactions. Am J Reprod Immunol 58 (2007) 98-110
12. Hanna J., Goldman-Wohl D., Hamani Y., Avraham I., Greenfield C., Natanson-Yaron S., et al. Decidual NK cells regulate key developmental processes at the human fetal-maternal interface. Nat Med 12 (2006) 1065-1074
13. Greenwood J.D., Minhas K., di Santo J.P., Makita M., Kiso Y., and Croy B.A. Ultrastructural studies of implantation sites from mice deficient in uterine natural killer cells. Placenta 21 (2000) 693-702
14. Graham C.H., Hawley T.S., Hawley R.G., MacDougall J.R., Kerbel R.S., Khoo N., et al. Establishment and characterization of first trimester human trophoblast cells with extended lifespan. Exp Cell Res 206 (1993) 204-211
15. Lewis M.P., Clements M., Takeda S., Kirby P.L., Seki H., Lonsdale L.B., et al. Partial characterization of an immortalized human trophoblast cell-line, TCL-1, which possesses a CSF-1 autocrine loop. Placenta 17 (1996) 137-146
16. Fest S., Brachwitz N., Schumacher A., Zenclussen M.L., Khan F., Wafula P.O., et al. Supporting the hypothesis of pregnancy as a tumor: survivin is upregulated in normal pregnant mice and participates in human trophoblast proliferation. Am J Reprod Immunol 59 (2008) 75-83
17. Boguslawski G., McGlynn P.W., Harvey K.A., and Kovala A.T. SU1498, an inhibitor of vascular endothelial growth factor receptor 2, causes accumulation of phosphorylated ERK kinases and inhibits their activity in vivo and in vitro. J Biol Chem 279 (2004) 5716-5724
18. Bulla R., Villa A., Bossi F., Cassetti A., Radillo O., Spessotto P., et al. VE-cadherin is a critical molecule for trophoblast-endothelial cell interaction in decidual spiral arteries. Exp Cell Res 303 (2005) 101-113
19. Debnath J., and Brugge J.S. Modelling glandular epithelial cancers in three-dimensional cultures. Nat Rev Cancer 5 (2005) 675-688
20. Taylor R.N., Grimwood J., Taylor R.S., McMaster M.T., Fisher S.J., and North R.A. Longitudinal serum concentrations of placental growth factor: evidence for abnormal placental angiogenesis in pathologic pregnancies. Am J Obstet Gynecol 188 (2003) 177-182
21. Levine R.J., Maynard S.E., Qian C., Lim K.H., England L.J., Yu K.F., et al. Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med 350 (2004) 672-683
22. Clark D.E., Smith S.K., He Y., Day K.A., Licence D.R., Corps A.N., et al. A vascular endothelial growth factor antagonist is produced by the human placenta and released into the maternal circulation. Biol Reprod 59 (1998) 1540-1548
23. Venkatesha S., Toporsian M., Lam C., Hanai J., Mammoto T., Kim Y.M., et al. Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat Med 12 (2006) 642-649
24. Lindheimer M.D., and Romero R. Emerging roles of antiangiogenic and angiogenic proteins in pathogenesis and prediction of preeclampsia. Hypertension 50 (2007) 35-36
25. Chung J.Y., Song Y., Wang Y., Magness R.R., and Zheng J. Differential expression of vascular endothelial growth factor (VEGF), endocrine gland derived-VEGF, and VEGF receptors in human placentas from normal and preeclamptic pregnancies. J Clin Endocrinol Metab 89 (2004) 2484-2490
26. Zhau Y., Fisher S.J., Janatpor M., Genbacev O., Dejana E., Wheelock M., et al. Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion. J Clin Invest 99 (1997) 2139-2151
27. Goldman-Who D.S., Ariel I., Geenfield C., Hochner-Celnikier D., Cross J., Fisher S., et al. Lack of human leukocyte antigen-G expression in extravillous trophoblasts is associated with preeclampsia. Mol Hum Reprod 6 (2000) 88-95
28. Masatsugu Ueda M., Terai Y., Kumagai K., Ueki K., Yamaguchi H., Akise D., et al. Vascular endothelial growth factor C gene expression is closely related to invasion phenotype in gynecological tumor cells. Gynecol Oncol 82 (2001) 162-166
29. Zhou Y., Bellingard V., Feng K.T., McMaster M., and Fisher S.J. Human cytotrophoblasts promote endothelial survival and vascular remodeling through secretion of Ang2, PlGF, and VEGF-C. Dev Biol 263 (2003) 114-125
30. Hiratsuka S., Kataoka Y., Nakao K., Nakamura K., Morikawa S., Tanaka S., et al. Vascular endothelial growth factor A (VEGF-A) is involved in guidance of VEGF receptor-positive cells to the anterior portion of early embryos. Mol Cell Biol 25 (2005) 355-363
31. Yang S., Xin X., Zlot C., Ingle G., Fuh G., Li B., et al. Vascular endothelial cell growth factor-driven endothelial tube formation is mediated by vascular endothelial cell growth factor receptor-2, a kinase insert domain-containing receptor. Arterioscler Thromb Vasc Biol 21 (2001) 1934-1940
32. Zhou Y., McMaster M., Woo K., Janatpour M., Perry J., Karpanen T., et al. Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndrome. Am J Pathol 160 (2002) 1405-1423
33. Karmakar S., and Das C. Modulation of ezrin and E-cadherin expression by IL-1beta and TGF-beta1 in human trophoblasts. J Reprod Immunol 64 (2004) 9-29
34. D'Souza-Schorey C. Disassembling adherens junctions: breaking up is hard to do. Trends Cell Biol. 15 (2005) 19-26
35. Rahnama F., Shafiei F., Gluckman P.D., Mitchell M.D., and Lobie P.E. Epigenetic regulation of human trophoblastic cell migration and invasion. Endocrinology 147 (2006) 5275-5283