Methylmercury disrupts the balance between phosphorylated and non-phosphorylated cofilin in primary cultures of mice cerebellar granule cells A proteomic study

Toxicology and Applied Pharmacology

Volumn 242, Issue 1, 2010, Pages 109-118

  Vendrell, Iolanda ^a,b   Carrascal, Montserrat ^c   Campos, Francisco ^a,b   Abián, Joaquin ^c   Suñol, Cristina ^a,b  

^a CSIC   (Spain)

^b CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

^c INST D INVESTIGACIONS B   (Spain)

Author keywords

Cerebellar granule neurons; Cofilin; In vitro; Methylmercury; Neuroproteome; Neurotoxicity

Indexed keywords

3 OXOACID COENZYME A TRANSFERASE; ACTIN; ALDEHYDE DEHYDROGENASE; ALPHA ENOLASE; CARBOXYLESTERASE; CATHEPSIN B; COFILIN; CREATINE KINASE; CYCLOPHILIN; DJ 1 PROTEIN; ELONGATION FACTOR; ELONGATION FACTOR 2; FUMARATE HYDRATASE; GALECTIN 3; GLYCEROPHOSPHOINOSITOL INOSITOLPHOSPHODIESTERASE; LACTATE DEHYDROGENASE; MALATE DEHYDROGENASE; METHYLMERCURY; MICROTUBULE ASSOCIATED PROTEIN; PARVALBUMIN; PEPTIDYLPROLYL ISOMERASE; PEROXIREDOXIN 1; PEROXIREDOXIN 6; PHOSPHATIDYLETHANOLAMINE; PHOSPHOGLYCERATE MUTASE; PROFILIN; PROHIBITIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; UBIQUINOL CYTOCHROME C REDUCTASE;

ACTIN FILAMENT; AMINO ACID SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL FUNCTION; CELL MIGRATION; CELL POLARITY; CELL SHAPE; CELL STRUCTURE; CELL VIABILITY; CEREBELLUM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GRANULE CELL; IN VITRO STUDY; LC 50; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MITOCHONDRION; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NEUROTOXICITY; NONHUMAN; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; PROTEOMICS; SYNAPSE; TWO DIMENSIONAL ELECTROPHORESIS;

ACTIN DEPOLYMERIZING FACTORS; ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CELL SURVIVAL; CEREBELLUM; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; IMAGE PROCESSING, COMPUTER-ASSISTED; ISOELECTRIC FOCUSING; MERCURY POISONING, NERVOUS SYSTEM; METHYLMERCURY COMPOUNDS; MICE; NERVE TISSUE PROTEINS; PHOSPHORYLATION; PROTEOMICS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

MUS;

EID: 70449707133     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.09.022     Document Type: Article

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