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Volumn 14, Issue 1, 2004, Pages 21-33

The Neuropathology of Septic Shock

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYTOKINE; INTERLEUKIN 1BETA; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA;

EID: 1042265202     PISSN: 10156305     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2004.tb00494.x     Document Type: Article
Times cited : (281)

References (80)
  • 3
    • 1042306181 scopus 로고    scopus 로고
    • Definitions for sepsis and multiple organ failure, and guidelines for the use of innovative therapies in sepsis
    • American College of Chest Physicians/Society of, Critical Care Medicine Consensus Conference (1998) Definitions for sepsis and multiple organ failure, and guidelines for the use of innovative therapies in sepsis. Crit Care Med 26:645-650.
    • (1998) Crit Care Med , vol.26 , pp. 645-650
  • 4
    • 0027249013 scopus 로고
    • Multifocal necrotizing leukoencephalopathy with pontine predilection in immunosuppressed patients: A clinicopathologic review of 16 cases
    • Anders KH, Becker PS, Holden JK, Sharer LR, Cornford ME, Hansen LA, Hamilton R, Vinters HV (1993) Multifocal necrotizing leukoencephalopathy with pontine predilection in immunosuppressed patients: a clinicopathologic review of 16 cases. Hum Pathol 24:897-904.
    • (1993) Hum Pathol , vol.24 , pp. 897-904
    • Anders, K.H.1    Becker, P.S.2    Holden, J.K.3    Sharer, L.R.4    Cornford, M.E.5    Hansen, L.A.6    Hamilton, R.7    Vinters, H.V.8
  • 5
    • 0033038308 scopus 로고    scopus 로고
    • Short-term variability of blood pressure and heart rate in Guillain-Barre syndrome without respiratory failure
    • Annane D, Baudrie V, Blanc AS, Laude D, Raphael JC, Elghozi JL (1999) Short-term variability of blood pressure and heart rate in Guillain-Barre syndrome without respiratory failure. Clin Sci (Lond) 96:613-621.
    • (1999) Clin Sci (Lond) , vol.96 , pp. 613-621
    • Annane, D.1    Baudrie, V.2    Blanc, A.S.3    Laude, D.4    Raphael, J.C.5    Elghozi, J.L.6
  • 7
    • 0027191429 scopus 로고
    • In situ endlabelling detects DNA strand breaks in apoptosis and other physiological and pathological states
    • Ansari B, Coates P J, Greenstein BD, Hall PA (1993) In situ endlabelling detects DNA strand breaks in apoptosis and other physiological and pathological states. J Pathol 170:18.
    • (1993) J Pathol , vol.170 , pp. 18
    • Ansari, B.1    Coates, P.J.2    Greenstein, B.D.3    Hall, P.A.4
  • 10
    • 0026710191 scopus 로고
    • Definitions for sepsis and organ failure and guidelines for use of innovative therapies in sepsis
    • The ACCP/SCCM Consensus Conference. American College of Chest Physician/Society of Critical Care Medicine
    • Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ (1992) Definitions for sepsis and organ failure and guidelines for use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference. American College of Chest Physician/Society of Critical Care Medicine. Chest 101:1644-1655.
    • (1992) Chest , vol.101 , pp. 1644-1655
    • Bone, R.C.1    Balk, R.A.2    Cerra, F.B.3    Dellinger, R.P.4    Fein, A.M.5    Knaus, W.A.6    Schein, R.M.7    Sibbald, W.J.8
  • 12
    • 0035953547 scopus 로고    scopus 로고
    • TREM-1 amplifies inflammation and is a crucial mediator of septic shock
    • Bouchon A, Facchetti F, Weigand MA, Colonna M (2001) TREM-1 amplifies inflammation and is a crucial mediator of septic shock. Nature 410: 1103-1107.
    • (2001) Nature , vol.410 , pp. 1103-1107
    • Bouchon, A.1    Facchetti, F.2    Weigand, M.A.3    Colonna, M.4
  • 13
    • 0024673023 scopus 로고
    • Cerebral blood flow is reduced in patients with sepsis syndrome
    • Bowton DL, Bertels NH, Prough DS, Stump DA (1989) Cerebral blood flow is reduced in patients with sepsis syndrome. Crit Care Med 17:399-403.
    • (1989) Crit Care Med , vol.17 , pp. 399-403
    • Bowton, D.L.1    Bertels, N.H.2    Prough, D.S.3    Stump, D.A.4
  • 14
    • 0023889666 scopus 로고
    • Interleukin-1 immunoreactive innervation of the human hypothalamus
    • Breder CD, Dinarello CA, Saper CB (1988) Interleukin-1 immunoreactive innervation of the human hypothalamus. Science 240:321-324.
    • (1988) Science , vol.240 , pp. 321-324
    • Breder, C.D.1    Dinarello, C.A.2    Saper, C.B.3
  • 15
    • 0027945999 scopus 로고
    • Regional induction of tumor necrosis factor alpha expression in the mouse brain after systemic lipopolysaccharide administration
    • Breder CD, Hazuka C, Ghayur T, Klug C, Huginin M, Yasuda K, Teng M, Saper CB (1994) Regional induction of tumor necrosis factor alpha expression in the mouse brain after systemic lipopolysaccharide administration. Proc Natl Acad Sci USA 91:11393-11397.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11393-11397
    • Breder, C.D.1    Hazuka, C.2    Ghayur, T.3    Klug, C.4    Huginin, M.5    Yasuda, K.6    Teng, M.7    Saper, C.B.8
  • 16
    • 0025011298 scopus 로고
    • Localization of nitric oxide synthase indicating a neural role for nitric oxide
    • Bredt DS, Hwang PM, Snyder SH (1990) Localization of nitric oxide synthase indicating a neural role for nitric oxide. Nature 347:768-770.
    • (1990) Nature , vol.347 , pp. 768-770
    • Bredt, D.S.1    Hwang, P.M.2    Snyder, S.H.3
  • 17
    • 0029147346 scopus 로고
    • Incidence, risk factors, and outcome of severe sepsis and septic shock in adults. A multicenter prospective study in intensive care units
    • French ICU Group for Severe Sepsis
    • Brun-Buisson C, Doyon F, Carlet J, Dellamonica P, Gouin F, Lepoutre A, Mercier JC, Offenstadt G, Régnier B for the French ICU Group for Severe Sepsis (1995) Incidence, risk factors, and outcome of severe sepsis and septic shock in adults. A multicenter prospective study in intensive care units. French ICU Group for Severe Sepsis. JAMA 274:968-974.
    • (1995) JAMA , vol.274 , pp. 968-974
    • Brun-Buisson, C.1    Doyon, F.2    Carlet, J.3    Dellamonica, P.4    Gouin, F.5    Lepoutre, A.6    Mercier, J.C.7    Offenstadt, G.8    Régnier, B.9
  • 19
    • 0022993837 scopus 로고
    • Cerebral circulation during endotoxin shock with special emphasis on the regional cerebral blood flow in vivo
    • Christenson JT, Kuikka JT, Owunwanne A, Al-Sarraf AA (1986) Cerebral circulation during endotoxin shock with special emphasis on the regional cerebral blood flow in vivo. Nucl Med Commun 7:531-540.
    • (1986) Nucl Med Commun , vol.7 , pp. 531-540
    • Christenson, J.T.1    Kuikka, J.T.2    Owunwanne, A.3    Al-Sarraf, A.A.4
  • 20
    • 0029037126 scopus 로고
    • The hypothalamic-pituitary-adrenal-axis and immune-mediated inflammation
    • Chrousos GP (1995) The hypothalamic-pituitary-adrenal-axis and immune-mediated inflammation. N Engl J Med 332:1351-1362.
    • (1995) N Engl J Med , vol.332 , pp. 1351-1362
    • Chrousos, G.P.1
  • 21
    • 0013915024 scopus 로고
    • Electron microscopy of the effect of gram-negative endotoxin on the blood-brain barrier
    • Clawson CC, Hartmann JF, Vernier RL (1966) Electron microscopy of the effect of gram-negative endotoxin on the blood-brain barrier. J Comp Neurol 127:183-198.
    • (1966) J Comp Neurol , vol.127 , pp. 183-198
    • Clawson, C.C.1    Hartmann, J.F.2    Vernier, R.L.3
  • 22
    • 0028864234 scopus 로고
    • Human ramified microglial cells produce nitric oxide upon Escherichia coli lipopolysaccharide and tumor necrosis factor alpha stimulation
    • Colasanti M, Persichini T, Pucchio TD, Gremo F, Lauro GM (1995) Human ramified microglial cells produce nitric oxide upon Escherichia coli lipopolysaccharide and tumor necrosis factor alpha stimulation. Neurosci Lett 200:144-146.
    • (1995) Neurosci Lett , vol.200 , pp. 144-146
    • Colasanti, M.1    Persichini, T.2    Pucchio, T.D.3    Gremo, F.4    Lauro, G.M.5
  • 23
    • 0035866060 scopus 로고    scopus 로고
    • Beta-amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis
    • Combs CK, Karlo JC, Kao SC, Landreth GE (2001) Beta-amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis. J Neurosci Res 21:1179-1188.
    • (2001) J Neurosci Res , vol.21 , pp. 1179-1188
    • Combs, C.K.1    Karlo, J.C.2    Kao, S.C.3    Landreth, G.E.4
  • 24
    • 0029046062 scopus 로고
    • Endothelial barrier resistance in multiple organs after septic and nonseptic challenges in the rat
    • Deng X, Wang X, Andersson R (1995) Endothelial barrier resistance in multiple organs after septic and nonseptic challenges in the rat. J Appl Physiol 78:2052-2061.
    • (1995) J Appl Physiol , vol.78 , pp. 2052-2061
    • Deng, X.1    Wang, X.2    Andersson, R.3
  • 25
    • 0026763167 scopus 로고
    • Endotoxin-induced activation of cerebral catecholamine and serotonin metabolism: Comparison with interleukin-1
    • Dunn AJ (1992) Endotoxin-induced activation of cerebral catecholamine and serotonin metabolism: comparison with interleukin-1. J Pharmacol Exp Ther 261:964-969.
    • (1992) J Pharmacol Exp Ther , vol.261 , pp. 964-969
    • Dunn, A.J.1
  • 26
    • 0033675213 scopus 로고    scopus 로고
    • Cytokine activation of the HPA axis
    • Dunn AJ (2000) Cytokine activation of the HPA axis. Ann N Y Acad Sci 917:608-617.
    • (2000) Ann N Y Acad Sci , vol.917 , pp. 608-617
    • Dunn, A.J.1
  • 27
    • 0030051298 scopus 로고    scopus 로고
    • The spectrum of septic encephalopathy. Definitions, etiologies, and mortalities
    • Eidelman LA, Putterman D, Putterman C, Sprung CL (1996) The spectrum of septic encephalopathy. Definitions, etiologies, and mortalities. JAMA 275:470-473.
    • (1996) JAMA , vol.275 , pp. 470-473
    • Eidelman, L.A.1    Putterman, D.2    Putterman, C.3    Sprung, C.L.4
  • 28
    • 0020149694 scopus 로고
    • Effects of dopamine of cerebral circulation and oxygen metabolism in endotoxic shock: An experimental study in dogs
    • Ekstrom-Jodal B, Larsson LE (1982) Effects of dopamine of cerebral circulation and oxygen metabolism in endotoxic shock: an experimental study in dogs. Crit Care Med 10:375-377.
    • (1982) Crit Care Med , vol.10 , pp. 375-377
    • Ekstrom-Jodal, B.1    Larsson, L.E.2
  • 29
    • 0029664477 scopus 로고    scopus 로고
    • CD14 mediate endotoxin induction of nitric oxide synthase in cultured brain glial cells
    • Galea E, Reis DJ, Fox ES, Xu H, Feinstein DL (1996) CD14 mediate endotoxin induction of nitric oxide synthase in cultured brain glial cells. J Neuroimmunol 64:19-28.
    • (1996) J Neuroimmunol , vol.64 , pp. 19-28
    • Galea, E.1    Reis, D.J.2    Fox, E.S.3    Xu, H.4    Feinstein, D.L.5
  • 30
    • 0036274927 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase pathway in the central nervous system and vasopressin release during experimental septic shock
    • Giusti-Paiva A, De Castro M, Antunes-Rodrigues J, Carnio EC (2002) Inducible nitric oxide synthase pathway in the central nervous system and vasopressin release during experimental septic shock. Crit Care Med 30:1306-1310.
    • (2002) Crit Care Med , vol.30 , pp. 1306-1310
    • Giusti-Paiva, A.1    De Castro, M.2    Antunes-Rodrigues, J.3    Carnio, E.C.4
  • 32
    • 0029794869 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase gene expression in vascular cell after transient focal ischemia
    • Iadecola C, Zhang F, Casey R, Clark HB, Ross ME (1996) Inducible nitric oxide synthase gene expression in vascular cell after transient focal ischemia. Stroke 27:1373-1380.
    • (1996) Stroke , vol.27 , pp. 1373-1380
    • Iadecola, C.1    Zhang, F.2    Casey, R.3    Clark, H.B.4    Ross, M.E.5
  • 35
    • 0030058595 scopus 로고    scopus 로고
    • An alteration in the gamma-aminobutyric acid receptor system in experimentally induced septic shock in rats
    • Kadoi Y, Saito S (1996) An alteration in the gamma-aminobutyric acid receptor system in experimentally induced septic shock in rats. Crit Care Med 24:298-305.
    • (1996) Crit Care Med , vol.24 , pp. 298-305
    • Kadoi, Y.1    Saito, S.2
  • 36
    • 0029869901 scopus 로고    scopus 로고
    • Impairment of the brain beta-adrenergic system during experimental endotoxemia
    • Kadoi Y, Saito S, Kunimoto F, Imai T, Fujita T (1996) Impairment of the brain beta-adrenergic system during experimental endotoxemia. J Surg Res 61:496-502.
    • (1996) J Surg Res , vol.61 , pp. 496-502
    • Kadoi, Y.1    Saito, S.2    Kunimoto, F.3    Imai, T.4    Fujita, T.5
  • 37
    • 0033016573 scopus 로고    scopus 로고
    • The molecular pathogenesis of endotoxic shock and organ failure
    • Karima R, Matsumoto S, Higashi H, Matsushima K (1999) The molecular pathogenesis of endotoxic shock and organ failure. Mol Med Today 5:123-132.
    • (1999) Mol Med Today , vol.5 , pp. 123-132
    • Karima, R.1    Matsumoto, S.2    Higashi, H.3    Matsushima, K.4
  • 39
    • 0033103979 scopus 로고    scopus 로고
    • Temporal and spatial relationships between lipopolysaccharide-induced expression of Fos, interleukin-1 beta and inducible nitric oxide synthase in rat brain
    • Konsman JP, Kelley K, Dantzer R (1999) Temporal and spatial relationships between lipopolysaccharide-induced expression of Fos, interleukin-1 beta and inducible nitric oxide synthase in rat brain. Neuroscience 89:535-548.
    • (1999) Neuroscience , vol.89 , pp. 535-548
    • Konsman, J.P.1    Kelley, K.2    Dantzer, R.3
  • 40
    • 85047679860 scopus 로고
    • Role of sympathetic nerve activity in endotoxin induced hypotension in cats
    • Koyama S, Manning J (1984) Role of sympathetic nerve activity in endotoxin induced hypotension in cats. Cardiovasc Res 19:32-37.
    • (1984) Cardiovasc Res , vol.19 , pp. 32-37
    • Koyama, S.1    Manning, J.2
  • 41
    • 0022636099 scopus 로고
    • Central impairment of renal nerve response to stimulation of medullary pressor area in rabbit endotoxic hypotension
    • Koyama S, Manning J (1986) Central impairment of renal nerve response to stimulation of medullary pressor area in rabbit endotoxic hypotension. Brain Res 366:217-223.
    • (1986) Brain Res , vol.366 , pp. 217-223
    • Koyama, S.1    Manning, J.2
  • 43
    • 0036042244 scopus 로고    scopus 로고
    • Metabolic encephalopathies
    • Kunze K (2002) Metabolic encephalopathies. J Neurol 249:1150-1159.
    • (2002) J Neurol , vol.249 , pp. 1150-1159
    • Kunze, K.1
  • 44
    • 0031683603 scopus 로고    scopus 로고
    • The bacterial endotoxin lipopolysaccharide has the ability to target the brain in upregulating its membrane CD14 receptor within specific cellular populations
    • Lacroix S, Feinstein D, Rivest (1998) The bacterial endotoxin lipopolysaccharide has the ability to target the brain in upregulating its membrane CD14 receptor within specific cellular populations. Brain Pathol 8:625-640.
    • (1998) Brain Pathol , vol.8 , pp. 625-640
    • Lacroix, S.1    Feinstein, D.2    Rivest3
  • 45
    • 0027132478 scopus 로고
    • A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study
    • Le Gall JR, Lemeshow S, F S (1993) A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA 270:2957-2963.
    • (1993) JAMA , vol.270 , pp. 2957-2963
    • Le Gall, J.R.1    Lemeshow, S.2
  • 46
    • 0035936945 scopus 로고    scopus 로고
    • NO as an autocrine mediator in the apoptosis of activated microglial cells: Correlation between activation and apoptosis of microglial cells
    • Lee P, Lee J, Kim S, Lee MS, Yagita H, Kim SY, Kim H, Suk K (2001) NO as an autocrine mediator in the apoptosis of activated microglial cells: correlation between activation and apoptosis of microglial cells. Brain Res 892:380-385.
    • (2001) Brain Res , vol.892 , pp. 380-385
    • Lee, P.1    Lee, J.2    Kim, S.3    Lee, M.S.4    Yagita, H.5    Kim, S.Y.6    Kim, H.7    Suk, K.8
  • 47
    • 0033584457 scopus 로고    scopus 로고
    • Disseminated intravascular coagulation
    • Levi M, Cate HT (1999) Disseminated intravascular coagulation. N Engl J Med 341:586-592.
    • (1999) N Engl J Med , vol.341 , pp. 586-592
    • Levi, M.1    Cate, H.T.2
  • 48
    • 0342723791 scopus 로고    scopus 로고
    • Nitric oxide in the pathogenesis of vascular disease
    • Li H, Forstermann U (2000) Nitric oxide in the pathogenesis of vascular disease. J Pathol 190: 244-254.
    • (2000) J Pathol , vol.190 , pp. 244-254
    • Li, H.1    Forstermann, U.2
  • 50
    • 0030010935 scopus 로고    scopus 로고
    • Sepsis-induced vasoparalysis does not involve the cerebral vasculature: Indirect evidence from autoregulation and carbon dioxide reactivity studies
    • Matta BF, Stow P (1996) Sepsis-induced vasoparalysis does not involve the cerebral vasculature: indirect evidence from autoregulation and carbon dioxide reactivity studies. Br J Anaesth 76: 790-794.
    • (1996) Br J Anaesth , vol.76 , pp. 790-794
    • Matta, B.F.1    Stow, P.2
  • 54
    • 0024541776 scopus 로고
    • Multiple microabscesses in the central nervous system: A clinicopathologic study
    • Pendlebury WW, Perl DP, Munoz DG (1989) Multiple microabscesses in the central nervous system: a clinicopathologic study. J Neuropathol Exp Neurol 48:290-300.
    • (1989) J Neuropathol Exp Neurol , vol.48 , pp. 290-300
    • Pendlebury, W.W.1    Perl, D.P.2    Munoz, D.G.3
  • 55
    • 0030070223 scopus 로고    scopus 로고
    • Modulation of cardiovascular control mechanisms and their interaction
    • Persson PB (1996) Modulation of cardiovascular control mechanisms and their interaction. Physiol Rev 76:193-232.
    • (1996) Physiol Rev , vol.76 , pp. 193-232
    • Persson, P.B.1
  • 58
    • 0032891837 scopus 로고    scopus 로고
    • Induction of pro-inflammatory cytokine mRNAs in the brain after peripheral injection of subseptic doses of lipopolysaccharide in the rat
    • Quan N, Stern EL, Whiteside MB, Herkenham M (1999) Induction of pro-inflammatory cytokine mRNAs in the brain after peripheral injection of subseptic doses of lipopolysaccharide in the rat. J Neuroimmunol 93:72-80.
    • (1999) J Neuroimmunol , vol.93 , pp. 72-80
    • Quan, N.1    Stern, E.L.2    Whiteside, M.B.3    Herkenham, M.4
  • 59
  • 60
    • 0031889132 scopus 로고    scopus 로고
    • Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
    • Sakahira H, Enari M, Nagata S (1998) Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391:969.
    • (1998) Nature , vol.391 , pp. 969
    • Sakahira, H.1    Enari, M.2    Nagata, S.3
  • 61
    • 0023095360 scopus 로고
    • Purpura cerebri in gram-negative septicaemia. A histological and immunohistochemical study
    • Schwenk J, Gosztonyi G (1987) Purpura cerebri in gram-negative septicaemia. A histological and immunohistochemical study. Histol Histopathol 2:57-66.
    • (1987) Histol Histopathol , vol.2 , pp. 57-66
    • Schwenk, J.1    Gosztonyi, G.2
  • 70
    • 0032905515 scopus 로고    scopus 로고
    • Regulation of the hypothalamic-Pituitary-Adrenal axis cytokines: Actions and mechanisms of action
    • Turnbull AW, Rivier CL (1999) Regulation of the hypothalamic-Pituitary-Adrenal axis cytokines: actions and mechanisms of action. Physiol Rev 79:1-71.
    • (1999) Physiol Rev , vol.79 , pp. 1-71
    • Turnbull, A.W.1    Rivier, C.L.2
  • 73
    • 0025833797 scopus 로고
    • Prevention of endotoxin-induced increase of cerebral oxygen consumption in dogs by propranolol pretreatment
    • Westerlind A, Larsson LE, Haggendal J, Ekstrom-Jodal B (1991) Prevention of endotoxin-induced increase of cerebral oxygen consumption in dogs by propranolol pretreatment. Acta Anaesthesiol Scand 35:745-749.
    • (1991) Acta Anaesthesiol Scand , vol.35 , pp. 745-749
    • Westerlind, A.1    Larsson, L.E.2    Haggendal, J.3    Ekstrom-Jodal, B.4
  • 74
    • 0035877050 scopus 로고    scopus 로고
    • Differential expression of nitric oxide synthases in bacterial meningitis: Role of the inducible isoform for blood-brain barrier breakdown
    • Winkler F, Koedel U, Kastenbauer S, Pfister HW (2001) Differential expression of nitric oxide synthases in bacterial meningitis: role of the inducible isoform for blood-brain barrier breakdown. J Infect Dis 183:1749-1759.
    • (2001) J Infect Dis , vol.183 , pp. 1749-1759
    • Winkler, F.1    Koedel, U.2    Kastenbauer, S.3    Pfister, H.W.4
  • 75
    • 0030614340 scopus 로고    scopus 로고
    • Interleukin (IL)-1β, IL-1 receptor antagonist, IL-10, and IL-13 gene expression in the central nervous system during systemic inflammation: Pathophysiological implications
    • Wong ML, Bongiorno PB, Rettori V, McCann SM, Licinio J (1997) Interleukin (IL)-1β, IL-1 receptor antagonist, IL-10, and IL-13 gene expression in the central nervous system during systemic inflammation: pathophysiological implications. Proc Natl Acad Sci USA 94:227-232
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 227-232
    • Wong, M.L.1    Bongiorno, P.B.2    Rettori, V.3    McCann, S.M.4    Licinio, J.5
  • 79
    • 0034641936 scopus 로고    scopus 로고
    • Apoptosis in the nervous system
    • Yuan J, Yankner BA (2000) Apoptosis in the nervous system. Nature 407:802-809.
    • (2000) Nature , vol.407 , pp. 802-809
    • Yuan, J.1    Yankner, B.A.2
  • 80
    • 0034031514 scopus 로고    scopus 로고
    • Metabolic encephalopathy in critically ill patients suffering from septic or nonseptic multiple organ failure
    • Zauner C, Gendo A, Kramer L, Kranz A, Grimm G, Madl C (2000) Metabolic encephalopathy in critically ill patients suffering from septic or nonseptic multiple organ failure. Crit Care Med 28:1310-1315.
    • (2000) Crit Care Med , vol.28 , pp. 1310-1315
    • Zauner, C.1    Gendo, A.2    Kramer, L.3    Kranz, A.4    Grimm, G.5    Madl, C.6


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