Involvement of the PI3K/AKT pathway in the hypoglycemic effects of saponins from Helicteres isora

Journal of Ethnopharmacology

Volumn 126, Issue 3, 2009, Pages 386-396

  Bhavsar, Shefalee K ^a   Föller, Michael ^b   Gu, Shuchen ^b   Vir, Sanjay ^c   Shah, Mamta B ^a   Bhutani, K K ^c   Santani, Dev D ^a   Lang, Florian ^b  

^a L M COLLEGE OF PHARMACY   (India)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

AKT; C2C12 myotubes; Glut4 translocation; GSK 3 ; Helicteres isora; PI3K

Indexed keywords

GLUCOSE TRANSPORTER 4; GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; HELICTERES ISORA EXTRACT; PHOSPHATIDYLINOSITOL 3 KINASE; PLANT EXTRACT; PROTEIN KINASE B; SAPOGENIN; SAPONIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GLYCOGEN SYNTHESIS; HELICTERES ISORA; HERB; IMMUNOFLUORESCENCE; INSULIN SENSITIVITY; MOUSE; MUSCLE CELL; NONHUMAN; PROTEIN TARGETING; SKELETAL MUSCLE; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA PRIMERS; HYPOGLYCEMIC AGENTS; INSULIN RESISTANCE; MASS SPECTROMETRY; MICE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SAPONINS; STERCULIACEAE;

HELICTERES ISORA;

EID: 70449678568     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.09.027     Document Type: Article

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