Hypoglycaemic effect of Helicteres isora bark extract in rats

Journal of Ethnopharmacology

Volumn 107, Issue 2, 2006, Pages 304-307

  Kumar, G ^a   Banu, G Sharmila ^b   Murugesan, A G ^a   Pandian, M Rajasekara ^b  

^a MANONMANIAM SUNDARANAR UNIVERSITY   (India)

^b MUTHAYAMMAL COLLEGE OF ARTS AND SCIENCE   (India)

Author keywords

Blood glucose levels; Helicteres isora (Sterculiaceae); Hypoglycaemic effect; Streptozotocin

Indexed keywords

GLUCOSE; HELICTERES ISORA EXTRACT; PLANT EXTRACT; TOLBUTAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS SOLUTION; ARTICLE; BARK; CONTROLLED STUDY; DRUG EFFECT; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; HELICTERES ISORA; HYPERGLYCEMIA; HYPOGLYCEMIA; MALE; MEDICINAL PLANT; NONHUMAN; RAT; STREPTOZOCIN DIABETES;

ACUTE TOXICITY TESTS; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; GLUCOSE TOLERANCE TEST; HYPOGLYCEMIC AGENTS; MALE; PLANT BARK; PLANT EXTRACTS; RATS; RATS, WISTAR; STERCULIACEAE; TIME FACTORS;

HELICTERES ISORA; MALVACEAE;

EID: 33747340541     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2006.05.007     Document Type: Article

References (27)

1. Bean M.F., Antoun M., Abramson D., Chang C.J., Mc Laughlin J.L., and Cassady J.M. Cucurbitacin B and isocucurbitacin B Cytotoxic components of Helicteres isora. Journal of Natural Product 48 (1985) 500-503
2. Chakrabarti R., Vikramadithyan R.K., Mullangi R., Sharma V.M., Jagadheshan H., Rao Y.N., Sairam P., and Rajagopalan R. Antidiabetic and hypolipidemic activity of Helicteres isora in animal models. Journal of Ethnopharmacology 81 (2002) 343-349
3. Chopra R.N., Nayar S.L., and Chopra I.C. Glossary of Indian Medicinal Plants. first ed. (1956), CSIR, New Delhi, India p. 131
4. Dabis G., Michon D., Gazenav J., and Ruffie A. interet clinique d'une strategie biologique adaptee au diabete sucre. La vie medicale 8 (1984) 277-290
5. Du Vigneaud V., and Karr V. Carbohydrate utilization and disappearance. Journal of Biological Chemistry 66 (1985) 281-300
6. In: Gilman A.G., Rall T.W., Nies A.S., and Tayer P. (Eds). Goodman and Gilman's the Pharmacological Basis of Therapeutics. eighth ed. (1990), Pergamon Press, New York 1317-1322
7. 50) calculations. Biometrics 12 (1956) 312-322
8. Jafari M.A., Aslam M., Javad K., and Singh S. Effect of Punica granatum L. (flowers) on blood glucose level in normal and alloxan induced diabetic rats. Journal of Ethnopharmacology 70 (2000) 309-314
9. Kirtikar K.R., Basu B.D., and An I.C.S. Indian Medicinal Plants vol. 1 (1995), International Book Distributors, Dehradun, India 371-372
10. Lotlikar M.M., and Rajaramma R. Pharmacology of hypoglycaemic principle isolated from the fruits of Momordica charantia Linn. Indian Journal of Pharmacy 28 (1966) 129-133
11. Nadkarni K.M., and Nadkarni A.K. Indian Materia Medica vol. 1 (1976), Popular Prakashan, Bombay, India 615-616
12. Naik S.R., Filho J.M.B., Dhuley J.N., and Deshmukh A. Possible mechanism of hypoglycaemic activity of basic acid, a natural product isolated from Bumelia sartorum. Journal of Ethnopharmacology 33 (1991) 37-44
13. Prajapathi, N.D., Purohit, S.S., Sharmi, A.K., Kumar, T., 2003. A Handbook of Medicinal Plants: A Complete Source Book. Agrobios (India), Shyam Printing Press, Jodhpur. p. 265.
14. National Institute of Health Guide for the Care and Use of Laboratory Animals, 1985. DHEW Publication (NIH), revised, Office of Science and Health Reports, DRR/NIH, Bethesda, USA.
15. Obatomi D.K., Bikomo E.O., and Temple V.J. Anti-diabetic properties of the African Mistletoe in streptozotocin induced diabetic rats. Journal of Ethnopharmacology 43 (1994) 13-17
16. Perez G.R.M., Zavala S.M.A., Parez G.S., and Parez G.C. Antidiabetic effect of compounds isolated from plants. Phytomedicine 5 (1998) 55-75
17. Peungvicha P., Thirawarapan S.S., Temsiririrkkul R., Watanabe H., Prasain J.K., and Kadota S. Hypoglycaemic effect of the water extract of Piper sarmentosum in tars. Journal of Ethnopharmacology 60 (1998) 27-32
18. Pohocha N., and Grampurohit N.D. Antispasmodic activity of the fruits of Helicteres isora Linn. Phytotherapy Research 15 (2001) 49-52
19. Qu W.H., Li J.G., and Wang M.S. Chemical studies on the Helicteres isora. Zhongguo Yaoke Daxue Xuebao 22 (1991) 203-206
20. Raman A., and Lau C. Antidiabetic properties of phytochemistry of Momordica charantia L. (Cucurbitaceae). Phytomedicine 2 (1996) 349-362
21. Roman-Ramos R., Flores-Saenz J.L., and Alarcon-Aguilar F.J. Antihypertensive effect of some edible plants. Journal of Ethnopharmacology 48 (1995) 25-32
22. Scheff'e H.A. A method for judging all contrasts in the analysis of variance. Biometrika 40 (1953) 87-104
23. Sharma M.K., Khare A.K., and Feroz H. Effect of neem oil on blood glucose levels on normal, hyperglycemic and diabetic animals. Indian Medicine Gazette 117 (1983) 380-383
24. Singh S.B., Singh A.K., and Thakur R.S. Chemical constituents of the leaves of Helicteres isora. Indian Journal of Pharmaceutical Sciences 46 (1984) 148-149
25. Steiner D.F., and Williams R.H. Action of phenetyl biguanide and related compounds. Diabetes 8 (1959) 154-157
26. Triender P. Determination of glucose using glucose oxidase with an alternative oxygen acceptor. Annual Clinical Biochemistry 6 (1969) 24-27
27. Yasuhiro T., Masataka T., Tomoco I.K., Yukiko K., Yasumaru H., Shigetoshi K., Masao H., Tsuneo N., Tohru K., Ken T., and Sutardjo S. Helisterculins A and B, two new (7.5′, 8.2′)-Neolignans, and Helisorin, the first (6.4′, 7.5′, 8.2′)-Neolignan, from the Indonesian medicinal plant Helicteres isora. Helvetica Chimica Acta 82 (1999) 408-417