Effects of three penetration enhancers on transcorneal permeation of cyclosporine

Cornea

Volumn 20, Issue 5, 2001, Pages 505-508

  Van Der Bijl, Pieter ^a,b   Van Eyk, Armorél D ^a   Meyer, David ^b  

^a STELLENBOSCH UNIVERSITY   (South Africa)

^b UNIVERSITY OF STELLENBOSCH   (South Africa)

Author keywords

Benzalkonium chloride; Chremophor EL; Dimethyl sulfoxide; Human cornea; Penetration enhancers; Permeability

Indexed keywords

BENZALKONIUM CHLORIDE; CREMOPHOR; CYCLOSPORIN A; DIMETHYL SULFOXIDE; PENETRATION ENHANCING AGENT;

ADULT; AGED; ARTICLE; CORNEA PERMEABILITY; CORNEA PRESERVATION; DRUG DIFFUSION; DRUG EFFECT; FLOW RATE; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BENZALKONIUM COMPOUNDS; BIOLOGICAL AVAILABILITY; BIOLOGICAL TRANSPORT; CORNEA; CYCLOSPORINE; DIMETHYL SULFOXIDE; GLYCEROL; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MIDDLE AGED; PERMEABILITY; VEHICLES;

EID: 0034977117     PISSN: 02773740     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003226-200107000-00013     Document Type: Article

References (36)

1. Cyclosporin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders
2. Clinical use of cyclosporine in ocular disease
3. Use of immunosuppressive agents in ocular diseases
4. Lokale behandlung des hornhauttransplantates beim menschen mit cyclosporin A
5. Cyclosporin A: Tissue levels following topical and systemic administration to rabbits
6. Pharmacokinetics of topical cyclosporin A in the rabbit eye
7. Intraocular penetration of topically applied cyclosporine
8. Penetration of 2% cyclosporin eyedrops into human aqueous humor
9. Ocular penetration of cyclosporine A: The rabbit eye
10. Ocular penetration of cyclosporin A in the rat eye
11. Corneal concentration and systemic absorption of cyclosporin-A following its topical application in the rabbit eye
12. Influence of vehicle and anterior chamber protein concentration on cyclosporine penetration through the isolated rabbit cornea
13. Penetration of cyclosporin A into the rabbit cornea and aqueous humor after topical drop and collagen shield administration
14. A compartmental model for the ocular pharmacokinetics of cyclosporine in rabbits
15. Tissue concentration of nanoencapsulated radiolabeled cyclosporin following peroral delivery in mice or ophthalmic application in rabbits
16. Ocular penetration of cyclosporin A. III: The human eye
17. Topical use of cyclosporin in the treatment of vernal keratoconjunctivitis
18. Topical treatment of severe corneal ulcers with cyclosporine A
19. Cyclosporine-containing collagen shields suppress corneal allograft rejection
20. Local cyclosporine therapy for experimental autoimmune uveitis in rats
21. Ultrastructural and immunohistochemical study on the effect of topical cyclosporine A in the rabbit eye
22. Influence of topical cyclosporine A and dissolvent on corneal epithelium permeability of fluorescein
23. Improved extemporaneous formulation of cyclosporine ophthalmic drops
24. Topically applied cyclosporine in Azone prolongs corneal allograft survival
25. The effect on the cornea of alpha cyclodextrin vehicle for cyclosporin eye drops
26. Effects of four penetration enhancers on corneal permeability of drugs in vitro
27. Ophthalmic preservatives as absorption promoters for ocular drug delivery
28. Comparative permeability of human vaginal and buccal mucosa
29. Diffusion rates of vasopressin through human vaginal and buccal mucosa
30. Permeation of sumatriptan through human vaginal and buccal mucosa
31. Relationship of chemical structure to corneal penetration and influence of low-viscosity solution on ocular bioavailability
32. Penetration of topical cyclosporine into the rabbit cornea, aqueous humor and serum
33. Pharmacokinetics of topical cyclosporin A in the rabbit eye
34. Effect of freezing on the permeability of human buccal and vaginal mucosa
35. Permeability of rabbit corneal epithelium to horseradish peroxidase after the influence of benzalkonium chloride
36. A comparison of corneal epithelial and endothelial toxicity of common ophthalmic preservatives