Expression levels of pituitary tumor transforming 1 and glutathione-S-transferase theta 3 are associated with the individual susceptibility to d-galactosamine-induced hepatotoxicity

Toxicology and Applied Pharmacology

Volumn 242, Issue 1, 2010, Pages 91-99

  Yun, Jun Won ^a,b   Kim, Chae Wook ^a   Bae, Il Hong ^a   Park, Young Ho ^a   Chung, Jin Ho ^b   Lim, Kyung Min ^a   Kang, Kyung Sun ^b  

^a AmorePacific Corporation   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

d galactosamine; Hepatotoxicity; Individual variation; Microarray analysis; Prediction; Toxicogenomics

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ASPARTATE AMINOTRANSFERASE; BILE ACID; BILIRUBIN; GALACTOSAMINE; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE A2; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE T3; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HELIX LOOP HELIX PROTEIN; SECURIN; UNCLASSIFIED DRUG;

AGED; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DISEASE SEVERITY; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; LIVER; LIVER BIOPSY; LIVER TOXICITY; MALE; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PREDICTION; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; DRUG-INDUCED LIVER INJURY; GALACTOSAMINE; GLUTATHIONE TRANSFERASE; LIVER; LIVER FUNCTION TESTS; MALE; NEOPLASM PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

ANIMALIA; RATTUS;

EID: 70449518976     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.09.017     Document Type: Article

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