Glutathione S-transferase: Genetics and role in toxicology

Toxicology Letters

Volumn 112-113, Issue , 2000, Pages 357-363

  Strange, Richard C ^a   Jones, Peter W ^a   Fryer, Anthony A ^a  

^a KEELE UNIVERSITY   (United Kingdom)

Author keywords

Basal cell carcinoma; Clinical outcome; Glutathione S transferase; Ovarian cancer; Polymorphism

Indexed keywords

GLUTATHIONE TRANSFERASE; ISOENZYME;

BLADDER CANCER; CHEMOTHERAPY; CONFERENCE PAPER; DISEASE COURSE; DISEASE PREDISPOSITION; ENZYME ACTIVITY; ENZYME STRUCTURE; GENE EXPRESSION; GENETIC POLYMORPHISM; GENOTYPE; HEAD AND NECK CANCER; HUMAN; LUNG CANCER; MULTIGENE FAMILY; PHENOTYPE; PRIORITY JOURNAL; TREATMENT OUTCOME;

CARCINOMA, BASAL CELL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GLUTATHIONE TRANSFERASE; HUMANS; OVARIAN NEOPLASMS; POLYMORPHISM, GENETIC; SKIN NEOPLASMS; TOXICOLOGY;

ARENE;

EID: 0034653362     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(99)00230-1     Document Type: Conference Paper

References (30)

1. Ali-Osman, F., Akande, A., Mao, J., 1995. Molecular cloning, characterisation and expression of novel functionally different human glutathione S-transferase-P-1 gene variant. In: Proceedings of the International ISSX Workshop on Glutathione S-Transferase, Taylor and Francis, London, pp. 1061-3439.
2. Autrup, H., 1999. Genetic polymorphisms in xenobiotica metabolizing enzymes as risk factors towards genotoxic response. Mutation Research, in press.
3. Board P.G. Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4. Biochem. J. 330:1998;827-831.
4. Board P.G., Baker R.T., Chelvanayagam G., Jermin L.S. Zeta, a novel class of glutathione S-transferases in a range of species from plants to humans. Biochem. J. 328:1997;929-935.
5. Coggan M., Whitbread L., Whittington A., Board P. Structure and organization of the human theta-class glutathione S-transferase and D-dopachrome tautomerase gene complex. Biochem. J. 334:1998;617-623.
6. Fijnemann R.J.A., Jansen R.C., van der Valk M.A., Demant P. High frequency of interactions between lung cancer susceptibility genes in the mouse: Mapping of Sluc5 to Sluc14. Cancer Res. 58:1998;4794-4798.
7. Goto I., Yoneda S., Yamamoto M., Kawajiri K. Prognostic significance of germ line polymorphisms of the CYP1A1 and glutathione S-transferase genes in patients with non-small cell lung cancer. Cancer Res. 56:1996;3725-3730.
8. Hall A.G., Autzen P., Cattan A.R., Malcolm A.J., Cole M., Kernahan J., Reid M.M. Expression of mu class glutathione S-transferase correlates with event-free survival in childhood acute lymphoblastic leukaemia. Cancer Res. 54:1994;5251-5254.
9. Harries L.W., Stubbins M.J., Forman D., Howard G.C.W., Wolf C.R. Identification of genetic polymorphism at the GSTP1 locus and association with susceptibility to bladder, testicular and prostate cancer. Carcinogenesis. 18:1997;641-644.
10. Harris M.J., Coggan M., Langton L., Wilson S.R., Board P.G. Polymorphism of the pi class glutathione S-transferase in normal populations and cancer patients. Pharmacogenetics. 8:1998;27-31.
11. Hayes J.D., Pulford D.J. The Glutathione S-transferase supergene family: Regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit. Rev. Biochem. Mol. Biol. 30:1995;445-600.
12. Hayes J.D., Strange R.C. Potential contribution of the glutathione S-transferase supergene family to resistance to oxidative stress. Free Rad. Res. Comm. 22:1995;193-207.
13. Heagerty A.H.M., Fitzgerald D., Smith A., Bowers B., Jones P., Fryer A.A., Zhao L., Alldersea J., Strange R.C. Glutathione S-transferase GSTM1 phenotypes and protection against cutaneous malignancy. Lancet. 343:1994;266-268.
14. Howells R.E.J., Redman C.W.E., Dhar K. et al. Association of glutathione S-transferase GSTM1 and GSTT1 null genotypes with clinical outcome in epithelial ovarian cancer. Clin. Cancer Res. 10:1998;2439-2445.
15. Inskip A., Elexperu-Camiruaga J., Buxton N. et al. Identification of polymorphism at the glutathione-S-transferase, GSTM3 locus: Evidence for linkage with GSTM1*A. Biochem. J. 312:1995;713-716.
16. Layton M.A., Jones P.W., Alldersea J., Strange R.C., Fryer A.A., Dawes P.T., Mattey D.L. The therapeutic response to D-pencillamine in rheumatoid arthritis: influence of glutathione S-transferase polymorphisms. Rheumatology. 38:1999;43-47.
17. Lear J.T., Smith A.G., Heagerty A.H.M., Bowers B., Jones P.W., Gilford J., Alldersea J., Strange R.C., Fryer A.A. Truncal site and detoxifying enzyme polymorphisms significantly reduce time to presentation of further primary cutaneous basal cell carcinoma. Carcinogenesis. 18:1997;1499-1503.
18. Lee W.-H., Isaacs W.B., Bova S., Nelson W.G. CG island methylation changes near the GSTP1 gene in prostatic carcinoma cells detected using the polymerase chain reaction: A new prostate cancer biomarker. Cancer Epidemiol. Biomarkers Prev. 6:1997;443-450.
19. Lo H.W., Ali-Osman F. Genomic cloning of hGSTP1*C, an allelic human pi class glutathione S-transferase gene variant and functional characterization of its retinoic acid response elements. J. Biol. Chem. 272:1997;32743-32749.
20. Matthias C., Bockmühl U., Jahnke V. et al. Polymorphism in cytochrome P450 CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers: studies in upper aerodigestive tract cancers. Pharmacogenetics. 8:1998;91-100.
21. Matthias C., Bockmühl U., Jahnke V. et al. The glutathione S-transferase GSTP1 polymorphism: effects on susceptibility to oral/pharyngeal and laryngeal carcinomas. Pharmacogenetics. 8:1998;1-6.
22. Mattey D., Hassell A.B., Plant M. et al. Association of polymorphism in the glutathione S-transferase, GSTM1, GSTM3, GSTP1 and GSTT1 loci with susceptibility and outcome in rheumatoid arthritis. Ann. Rheumat. Dis. 58:1999;164-168.
23. McLellan R.A., Oscarson M., Alexandrie A.K., Seidegard J., Evans D.A., Rannug A., Ingelman-Sundberg M. Characterization of a human glutathione S-transferase mu cluster containing a duplicated GSTM1 gene that causes ultrarapid enzyme activity. Mol. Pharmacol. 52:1997;958-965.
24. Moisio, A.L., Sistonen, P., Mecklin, J.P., Jarvinen, H., Peltomaki, P., 1998. Genetic polymorphisms in carcinogen metabolism and their association to hereditary nonpolyposis colon cancer. Gastroenterology 115, 1387-1394.
25. Pemble S.E., Wardle A.F., Taylor J.B. Glutathione S-transferase class kappa: characterization by the cloning of rat mitochondrial GST and identification of a human homologue. Biochem. J. 319:1996;749-754.
26. Ramachandran S., Lear J.T., Ramsay H. et al. Presentation with multiple cutaneous basal cell carcinomas: Association of glutathione S-transferase and cytochrome P450 genotypes with clinical phenotype. Cancer Epidemiol. Biomarkers Prev. 8:1999;61-67.
27. Rebbeck T.R. Molecular epidemiology of the human glutathione S-transferase genotypes GSTM1 and GSTT1 in cancer susceptibility. Cancer Epidemiol. Biomarkers Prev. 6:1997;733-743.
28. Ryberg D., Skaug V., Hewer A. et al. Genotypes of glutathione transferase M1 and P1 and their significance for lung adduct levels and cancer risk. Carcinogenesis. 18:1997;1285-1289.
29. Strange, R.C., Fryer, A.A., 1999. The glutathione S-transferases: influence of polymorphism on susceptibility to cancer. In: Boffetta, P., Caporaso, N., Cuzick, J., Lang, M., Vineis, P. (Eds.), Metabolic Polymorphisms and Cancer. IARC Scientific Publications, Lyon No. 148, 231-249.
30. Xu S., Wang Y., Roe B., Pearson W.R. Characterization of the human class mu glutathione S-transferase gene cluster and the GSTM1 deletion. J. Biol. Chem. 273:1998;3517-3527.