High concentrations of dexamethasone suppress the proliferation but not the differentiation or further maturation of human osteoblast precursors in vitro: Relevance to glucocorticoid-induced osteoporosis

Rheumatology

Volumn 40, Issue 1, 2001, Pages 74-83

  Walsh, S ^a   Jordan, G R ^b   Jefferiss, C ^a   Stewart, K ^a   Beresford, J N ^a  

^a University of Bath   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Alkaline phosphatase; Bone marrow stromal cells; Colony forming unit; Dexamethasone; Flow cytometry; Glucocortoid induced osteoporosis; Growth factor receptors; Integrins; Osteoblasts; STRO 1

Indexed keywords

ALKALINE PHOSPHATASE; ALPHA2 INTEGRIN; ALPHA4 INTEGRIN; BETA1 INTEGRIN; DEXAMETHASONE; FIBROBLAST GROWTH FACTOR RECEPTOR; GLUCOCORTICOID; GROWTH FACTOR; GROWTH FACTOR RECEPTOR; INTEGRIN; MARKER; MONOCLONAL ANTIBODY; NERVE GROWTH FACTOR RECEPTOR; PARATHYROID HORMONE RECEPTOR; PARATHYROID HORMONE RELATED PROTEIN; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN SUBUNIT; SCLEROPROTEIN; SOMATOMEDIN C RECEPTOR; STRO 1; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BONE ATROPHY; BONE DEVELOPMENT; BONE MARROW CELL; CELL ADHESION; CELL COUNT; CELL DIFFERENTIATION; CELL GROWTH; CELL MATURATION; CELL PROLIFERATION; CLINICAL ARTICLE; COLONY FORMING UNIT F; CONCENTRATION RESPONSE; CONTROLLED STUDY; DONOR; DRUG INDUCED DISEASE; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; OSTEOBLAST; OSTEOPOROSIS; PRIORITY JOURNAL; PROGENY; RHEUMATOID ARTHRITIS; STEM CELL; STROMA CELL;

EID: 0035144210     PISSN: 14620324     EISSN: None     Source Type: Journal    
DOI: 10.1093/rheumatology/40.1.74     Document Type: Article

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