In vitro and in vivo differentiation of human umbilical cord derived stem cells into endothelial cells

Journal of Cellular Biochemistry

Volumn 100, Issue 3, 2007, Pages 608-616

  Wu, Kai Hong ^a   Zhou, Bin ^b   Lu, Shi Hong ^b   Feng, Bin ^a,c   Yang, Shao Guang ^b   Du, Wei Ting ^b   Gu, Dong Sheng ^b   Han, Zhong Chao ^b   Liu, Ying Long ^a,d  

^a PEKING UNION MEDICAL COLLEGE   (China)

^b INSTITUTE OF HEMATOLOGY AND BLOOD DISEASES HOSPITAL   (China)

^c Central Hospital of Nanchong   (China)

^d Pediatric Cardiac Center   (China)

Author keywords

Endothelial differentiation; Human umbilical cord; Stem cells; Tissue engineering

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CD31 ANTIGEN; CD34 ANTIGEN; VASCULOTROPIN;

ADOLESCENT; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CELL POPULATION; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIMB ISCHEMIA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; TISSUE ENGINEERING; TISSUE GRAFT; UMBILICAL CORD BLOOD; VASCULARIZATION;

ADIPOCYTES; CELL DIFFERENTIATION; CULTURE MEDIA; ENDOTHELIUM, VASCULAR; FIBROBLAST GROWTH FACTOR 2; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HINDLIMB SUSPENSION; HUMANS; OSTEOCLASTS; TISSUE ENGINEERING; UMBILICAL CORD; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 33846628657     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21078     Document Type: Article

References (19)

1. Ballas CB, Zielske SP, Gerson SL. 2002. Adult bone marrow stem cells for cell and gene therapies: Implications for greater use. J Cell Biochem Suppl 38:20-28.
2. Cao Y, Sun Z, Liao L, Meng Y, Han Q, Zhao RC. 2005. Human adipose tissue-derived stem cells differentiate into endothelial cells in vitro and improve postnatal neovascularization in vivo. Biochem Biophys Res Commun 332:370-379.
3. Hu Y, Davison F, Zhang Z, Xu Q. 2003. Endothelial replacement and angiogenesis in arteriosclerotic lesions of allografts are contributed by circulating progenitor cells. Circulation 108:3122-3127.
4. Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR, Reyes M, Lenvik T, Lund T, Blackstad M, Du J, Aldrich S, Lisberg A, Low WC, Largaespada DA, Verfaillie CM. 2002. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418:41-49.
5. Levenberg S, Rouwkema J, Macdonald M, Garfein ES, Kohane DS, Darland DC, Marini R, van Blitterswijk CA, Mulligan RC, D'Amore PA, Langer R. 2005. Engineering vascularized skeletal muscle tissue. Nat Biotechnol 23:879-884.
6. Li S, Zhou B, Han ZC. 2006. Therapeutic neovascularization by transplantation of mobilized peripheral blood mononuclear cells for limb ischemia. A comparison between CD34+ and CD34- mononuclear cells. Thromb Haemost 95:301-311.
7. Messina A, Bortolotto SK, Cassell OC, Kelly J, Abberton KM, Morrison WA. 2005. Generation of a vascularized organoid using skeletal muscle as the inductive source. Faseb J 19:1570-1572.
8. Nowak G, Karrar A, Holmen C, Nava S, Uzunel M, Hultenby K, Sumitran-Holgersson S. 2004. Expression of vascular endothelial growth factor receptor-2 or Tie-2 on peripheral blood cells defines functionally competent cell populations capable of reendothelialization. Circulation 110:3699-3707.
9. Oswald J, Boxberger S, Jorgensen B, Feldmann S, Ehninger G, Bornhauser M, Werner C. 2004. Mesenchymal stem cells can be differentiated into endothelial cells in vitro. Stem Cells 22:377-384.
10. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak DR. 1999. Multilineage potential of adult human mesenchymal stem cells. Science 284:143-147.
11. Prasad Chennazhy K, Krishnan LK. 2005. Effect of passage number and matrix characteristics on differentiation of endothelial cells cultured for tissue engineering. Biomaterials 26:5658-5667.
12. Romanov YA, Svintsitskaya VA, Smirnov VN. 2003. Searching for alternative sources of postnatal human mesenchymal stem cells: Candidate MSC-like cells from umbilical cord. Stem Cells 21:105-110.
13. Schmidt D, Breymann C, Weber A, Guenter CI, Neuenschwander S, Zund G, Turina M, Hoerstrup SP. 2004. Umbilical cord blood derived endothelial progenitor cells for tissue engineering of vascular grafts. Ann Thorac Surg 78:2094-2098.
14. Shen G, Tsung HC, Wu CF, Liu XY, Wang XY, Liu W, Cui L, Cao YL. 2003. Tissue engineering of blood vessels with endothelial cells differentiated from mouse embryonic stem cells. Cell Res 13:335-341.
15. Wang HS, Hung SC, Peng ST, Huang CC, Wei HM, Guo YJ, Fu YS, Lai MC, Chen CC. 2004. Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord. Stem Cells 22:1330-1337.
16. Wu K, Liu YL, Cui B, Han Z. 2006. Application of stem cells for cardiovascular grafts tissue engineering. Transpl Immunol 16:1-7.
17. Yang C, Zhang ZH, Li ZJ, Yang RC, Qian GQ, Han ZC. 2004. Enhancement of neovascularization with cord blood CD133+ cell-derived endothelial progenitor cell transplantation. Thromb Haemost 91:1202-1212.
18. Zhang H, Fazel S, Tian H, Mickle DA, Weisel RD, Fujii T, Li RK. 2005. Increasing donor age adversely impacts beneficial effects of bone marrow but not smooth muscle myocardial cell therapy. Am J Physiol Heart Circ Physiol 289:H2089-H2096.
19. Zhou B, Bi YY, Han ZB, Ren H, Fang ZH, Yu XF, Poon MC, Han ZC. 2006. G-CSF-mobilized peripheral blood mononuclear cells from diabetic patients augment neovascularization in ischemic limbs but with impaired capability. J Thromb Haemost 4:993-1002.