Diastereoselective synthesis of pyrrolidines via 1,3-dipolar cycloaddition of a chiral azomethine ylide

Tetrahedron Letters

Volumn 50, Issue 51, 2009, Pages 7175-7179

  Karthikeyan, K ^a   Senthil Kumar, R ^a   Muralidharan, D ^a   Perumal, P T ^a  

^a CENTRAL LEATHER RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AZOMETHINE YLIDE; GLUCOSE; PYRROLIDINE DERIVATIVE;

ARTICLE; CHIRALITY; CYCLOADDITION; DRUG STRUCTURE; DRUG SYNTHESIS; STEREOCHEMISTRY; STEREOISOMERISM;

EID: 70449102945     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.10.030     Document Type: Article

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61. 3): δ 1.43 (s, 6H), 3.41 (d, 1H, J = 13.0 Hz, -NCHH), 3.45 (dd, 1H, J = 8.5, 1.6 Hz, H-3a), 3.84 (d, 1H, J = 13.0 Hz, -NCHH), 3.86 (t, 1H, J = 8.4 Hz, H-6a), 4.25 (d, 1H, J = 2.3 Hz, H-3), 4.37 (d, 1H, J = 9.2 Hz, H-1), 5.09-5.16 (m, 3H), 5.31 (dd, 1H, J = 5.4, 2.3 Hz, H-2′), 6.07 (d, 1H, J = 5.4 Hz, H-1′), 7.22-7.26(m, 7H, Ar-H), 7.32-7.37
62. Crystallographic data for the structure 5c in this Letter have been deposited with the Cambridge Crystallographic Data centre as supplemental Publication No. CCDC-689250. Copies of the data can be obtained, free of charge on application to CCDC, 12 Union Road, Cambridge CB2 1EZ, UK (fax: +44 01223 336033 or email: deposit@ccdc.cam.ac.uk).
63. Crystallographic data for the structure 8c in this Letter have been deposited with the Cambridge Crystallographic Data centre as supplemental Publication No. CCDC-699267. Copies of the data can be obtained, free of charge on application to CCDC, 12 Union Road, Cambridge CB2 1EZ, UK (fax: +44 01223 336033 or email: deposit@ccdc.cam.ac.uk).