-
2
-
-
0030087854
-
Cytotoxic xanthones from Garcinia hanburyi
-
Asano, J., Chiba, K., Tada, M., and Yoshii, T. (1996). Cytotoxic xanthones from Garcinia hanburyi. Phytochemistry, 41, 815-820
-
(1996)
Phytochemistry
, vol.41
, pp. 815-820
-
-
Asano, J.1
Chiba, K.2
Tada, M.3
Yoshii, T.4
-
3
-
-
31844445117
-
The chief constituents of gamboge resins. 1. Chemistry of gamboges
-
Auterhoff, H., Frauendorf, H., Liesenklas, W., and Schwandt, C. (1962). The chief constituents of gamboge resins. 1. Chemistry of gamboge. Arch Pharm, 295, 833-846
-
(1962)
Arch Pharm
, Issue.295
, pp. 833-846
-
-
Auterhoff, H.1
Frauendorf, H.2
Liesenklas, W.3
Schwandt, C.4
-
6
-
-
31844434032
-
Inhibition of human telomerase reverse transcriptase gene expression ganbogic acid in human hepatoma SMMC-7721 cells
-
Guo, Q. L., Lin, S. S., You, Q. D., Gu, H. Y., Yu, J., Zhao, L., Qi, Q., Liang, F., Tan, Z., and Wang, X. T. (2006a). Inhibition of human telomerase reverse transcriptase gene expression ganbogic acid in human hepatoma SMMC-7721 cells. Life Sci, 78, 1238-1245
-
(2006)
Life Sci
, vol.78
, pp. 1238-1245
-
-
Guo, Q.L.1
Lin, S.S.2
You, Q.D.3
Gu, H.Y.4
Yu, J.5
Zhao, L.6
Qi, Q.7
Liang, F.8
Tan, Z.9
Wang, X.T.10
-
7
-
-
33747081043
-
Toxicological studies of gambogic acid and its potential targets in experimental animals
-
Guo, Q. L., Qi, Q., You, Q. D., Gu, H. Y., Zhao, L., and Wu, Z. Q. (2006b). Toxicological studies of gambogic acid and its potential targets in experimental animals. Basic Clin Pharmacol Toxicol, 99, 178-184
-
(2006)
Basic Clin Pharmacol Toxicol
, vol.99
, pp. 178-184
-
-
Guo, Q.L.1
Qi, Q.2
You, Q.D.3
Gu, H.Y.4
Zhao, L.5
Wu, Z.Q.6
-
8
-
-
0024330631
-
Quantitative evaluation of targeted drug delivery systems
-
Gupta, P. K., and Hung, C. T. (1989). Quantitative evaluation of targeted drug delivery systems. Int J Pharm, 56, 217-226
-
(1989)
Int J Pharm
, vol.56
, pp. 217-226
-
-
Gupta, P.K.1
Hung, C.T.2
-
9
-
-
34547609631
-
Pharmacokinetics, tissue distribution and excretion of gambogic acid in rats
-
Hao, K., Liu, X. Q., Wang, G. J., and Zhao, X. P. (2007). Pharmacokinetics, tissue distribution and excretion of gambogic acid in rats. Eur J Drug Metab Pharmacokinet, 32, 63-68.
-
(2007)
Eur J Drug Metab Pharmacokinet
, vol.32
, pp. 63-68
-
-
Hao, K.1
Liu, X.Q.2
Wang, G.J.3
Zhao, X.P.4
-
10
-
-
33646172454
-
Novel formulations of taxanes: A review Old wine in a new bottle?
-
Hennenfent, K. L., and Govindan, R. (2005). Novel formulations of taxanes: a review. Old wine in a new bottle? Ann Oncol, 17, 735-749
-
(2005)
Ann Oncol
, vol.17
, pp. 735-749
-
-
Hennenfent, K.L.1
Govindan, R.2
-
12
-
-
24744435348
-
A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid
-
Kasibhatla, S., Jessen, K. A., Maliartchouk, S., Wang, J. Y., English, N. M., Drewe, J., Qiu, L., Archer, S. P., Ponce, A. E., Sirisoma, N., Jiang, S., Zhang, H. Z., Gehlsen, K. R., Cai, S. X., Green, D. R., and Tseng, B. (2005). A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid. Proc Natl Acad Sci USA, 102, 12095-12100
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 12095-12100
-
-
Kasibhatla, S.1
Jessen, K.A.2
Maliartchouk, S.3
Wang, J.Y.4
English, N.M.5
Drewe, J.6
Qiu, L.7
Archer, S.P.8
Ponce, A.E.9
Sirisoma, N.10
Jiang, S.11
Zhang, H.Z.12
Gehlsen, K.R.13
Cai, S.X.14
Green, D.R.15
Tseng, B.16
-
13
-
-
36248989188
-
Chitosan and its derivatives for tissue engineering applications
-
Kim, I. Y., Seo, S. J., Moon, H. S., Yoo, M. K., Park, I. Y., Kim, B. C., and Cho, C. S. (2008). Chitosan and its derivatives for tissue engineering applications. Biotechnol Adv, 26, 1-21.
-
(2008)
Biotechnol Adv
, vol.26
, pp. 1-21
-
-
Kim, I.Y.1
Seo, S.J.2
Moon, H.S.3
Yoo, M.K.4
Park, I.Y.5
Kim, B.C.6
Cho, C.S.7
-
14
-
-
1642541103
-
Polymeric micelles for delivery of poorly water- soluble compounds
-
Kwon, G. S. (2003). Polymeric micelles for delivery of poorly water- soluble compounds. Crit Rev Ther Drug Carrier Syst, 20, 357-403.
-
(2003)
Crit Rev Ther Drug Carrier Syst
, vol.20
, pp. 357-403
-
-
Kwon, G.S.1
-
15
-
-
0030590446
-
Polymeric micelles as new drug carriers
-
Kwon, G. S., and Okano, T. (1996). Polymeric micelles as new drug carriers. Adv Drug Deliv Rev, 21, 107-116
-
(1996)
Adv Drug Deliv Rev
, vol.21
, pp. 107-116
-
-
Kwon, G.S.1
Okano, T.2
-
16
-
-
84989029929
-
Isogambogic acid and isomorellinol from Garcinia hanburyi
-
Lin, L. J., Lin, L. Z., Pezzuto, J. M., Cordell, G. A., and Ruangrungsi, N. (1993). Isogambogic acid and isomorellinol from Garcinia hanburyi. Magn Reson Chem, 31, 340-347
-
(1993)
Magn Reson Chem
, vol.31
, pp. 340-347
-
-
Lin, L.J.1
Lin, L.Z.2
Pezzuto, J.M.3
Cordell, G.A.4
Ruangrungsi, N.5
-
17
-
-
23844463880
-
Anticancer effect and apoptosis induction of gambogic acid in human gastric cancer line BGC-823
-
Liu, W., Guo, Q. L., You, Q. D., Zhao, L., Gu, H. Y., and Yuan, S. T. (2005). Anticancer effect and apoptosis induction of gambogic acid in human gastric cancer line BGC-823. World J Gastroenterol, 11, 3655-3659
-
(2005)
World J Gastroenterol
, vol.11
, pp. 3655-3659
-
-
Liu, W.1
Guo, Q.L.2
You, Q.D.3
Zhao, L.4
Gu, H.Y.5
Yuan, S.T.6
-
18
-
-
60749108001
-
Polymeric drugs for efficient tumor targeted drug delivery based on EPR-effect
-
Maeda, H., Bharate, G. Y., and Daruwalla, J. (2009). Polymeric drugs for efficient tumor targeted drug delivery based on EPR-effect. Eur J Pharm Biopharm, 71, 409-419
-
(2009)
Eur J Pharm Biopharm
, vol.71
, pp. 409-419
-
-
Maeda, H.1
Bharate, G.Y.2
Daruwalla, J.3
-
19
-
-
35648984010
-
Polymeric micelles for drug targeting
-
Mahmud, A., Xiong, X. B., Aliabadi, H. M., and Lavasanifar, A. (2007). Polymeric micelles for drug targeting. J Drug Target, 15, 553-584
-
(2007)
J Drug Target
, vol.15
, pp. 553-584
-
-
Mahmud, A.1
Xiong, X.B.2
Aliabadi, H.M.3
Lavasanifar, A.4
-
20
-
-
35348949634
-
Paclitaxel: A review of adverse toxicities and novel delivery strategies
-
Marupudi, N. I., Han, J. E., Li, K. W., Renard, V. M., Tyler, B. M., and Brem, H. (2007). Paclitaxel: a review of adverse toxicities and novel delivery strategies. Expert Opin Drug Saf, 6, 609-621
-
(2007)
Expert Opin Drug Saf
, vol.6
, pp. 609-621
-
-
Marupudi, N.I.1
Han, J.E.2
Li, K.W.3
Renard, V.M.4
Tyler, B.M.5
Brem, H.6
-
21
-
-
33746024992
-
Chitosan chemistry: Relevance to the biomedical sciences
-
Muzzarelli, R. A. A., and Muzzarelli, C. (2005). Chitosan chemistry: relevance to the biomedical sciences. Adv Polym Sci, 186, 151-209.
-
(2005)
Adv Polym Sci
, vol.186
, pp. 151-209
-
-
Muzzarelli, R.A.A.1
Muzzarelli, C.2
-
22
-
-
36148996510
-
Stable drug encapsulation in micelles and microemulsions
-
Narang, A. S., Delmarre, D., and Gao, D. (2007). Stable drug encapsulation in micelles and microemulsions. Int J Pharm, 345, 9-25.
-
(2007)
Int J Pharm
, vol.345
, pp. 9-25
-
-
Narang, A.S.1
Delmarre, D.2
Gao, D.3
-
23
-
-
33750136313
-
Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery
-
Nishiyama, N., and Kataoka, K. (2006). Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery, Pharmacol Ther, 112, 630-648
-
(2006)
Pharmacol Ther
, vol.112
, pp. 630-648
-
-
Nishiyama, N.1
Kataoka, K.2
-
24
-
-
35349029248
-
Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway
-
Pandey, M. K., Sung, B., Ahn, K. S., Kunnumakkara, A. B., Chaturvedi, M. M., and Aggarwal, B. B. (2007). Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway. Blood, 110, 3517-3525
-
(2007)
Blood
, vol.110
, pp. 3517-3525
-
-
Pandey, M.K.1
Sung, B.2
Ahn, K.S.3
Kunnumakkara, A.B.4
Chaturvedi, M.M.5
Aggarwal, B.B.6
-
25
-
-
0026541171
-
Serum opsonin and liposomes: Their interaction and opsonophagocytosis
-
Patel, H. M. (1992). Serum opsonin and liposomes: their interaction and opsonophagocytosis. Crit Rev Ther Drug Carrier Syst, 9, 39-90.
-
(1992)
Crit Rev Ther Drug Carrier Syst
, vol.9
, pp. 39-90
-
-
Patel, H.M.1
-
26
-
-
42749092824
-
Studies on the toxicity of gambogic acid in rats
-
Qi, Q., You, Q. D., Gu, H. Y., Zhao, L., Liu, W., Lu, N., and Guo, Q. L. (2008). Studies on the toxicity of gambogic acid in rats. J Ethnopharmacol, 117, 433-438
-
(2008)
J Ethnopharmacol
, vol.117
, pp. 433-438
-
-
Qi, Q.1
You, Q.D.2
Gu, H.Y.3
Zhao, L.4
Liu, W.5
Lu, N.6
Guo, Q.L.7
-
27
-
-
62649086512
-
PEG conjugated N-octyl-O-sulfate chitosan micelles for delivery of paclitaxel: In vitro characterization and in vivo evaluation
-
Qu, G. W., Yao, Z., Zhang, C., Wu, X. L., and Ping, Q. N. (2009). PEG conjugated N-octyl-O-sulfate chitosan micelles for delivery of paclitaxel: in vitro characterization and in vivo evaluation. Eur J Pharm Sci, 37, 98-105.
-
(2009)
Eur J Pharm Sci
, vol.37
, pp. 98-105
-
-
Qu, G.W.1
Yao, Z.2
Zhang, C.3
Wu, X.L.4
Ping, Q.N.5
-
28
-
-
0035850224
-
Structure and design of polymeric surfactantbased drug delivery systems
-
Torchilin, V. P. (2001). Structure and design of polymeric surfactantbased drug delivery systems. J Contr Rel, 73, 137-172
-
(2001)
J Contr Rel
, vol.73
, pp. 137-172
-
-
Torchilin, V.P.1
-
29
-
-
34248637901
-
The promise of chitosan microspheres in drug delivery systems
-
Varshosaz, J. (2007). The promise of chitosan microspheres in drug delivery systems. Expert Opin Drug Deliv, 4, 263-273
-
(2007)
Expert Opin Drug Deliv
, vol.4
, pp. 263-273
-
-
Varshosaz, J.1
-
30
-
-
14644405045
-
Polymeric micelles for delivery of poorly soluble drugs: Preparation and anticancer activity in vitro of paclitaxel incorporated into mixed micelles based on poly(ethylene glycol)-lipid conjugate and positively charged lipids
-
DOI 10.1080/10611860400011935
-
Wang, J., Mongayt, D., and Torchilin, V. P. (2005). Polymeric micelles for delivery of poorly soluble drugs: preparation and anticancer activity in vitro of paclitaxel incorporated into mixed micelles based on poly(ethylene glycol)-lipid conjugate and positively charged lipids. J Drug Target, 13, 73-80. (Pubitemid 40309464)
-
(2005)
Journal of Drug Targeting
, vol.13
, Issue.1
, pp. 73-80
-
-
Wang, J.1
Mongayt, D.2
Torchilin, V.P.3
-
31
-
-
20344405555
-
Gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase mRNA expression in the cells
-
Wu, Z. Q., Guo, Q. L., You, Q. D., Zhao, L., and Gu, H. Y. (2004). Gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase mRNA expression in the cells. Biol Pharm Bull, 27, 1769-1774
-
(2004)
Biol Pharm Bull
, vol.27
, pp. 1769-1774
-
-
Wu, Z.Q.1
Guo, Q.L.2
You, Q.D.3
Zhao, L.4
Gu, H.Y.5
-
32
-
-
33947172648
-
A series of novel chitosan derivatives: Synthesis, characterization and micellar solubilization of paclitaxel
-
Yao, Z., Zhang, C., Ping, Q. N., and Yu, L. (2007). A series of novel chitosan derivatives: synthesis, characterization and micellar solubilization of paclitaxel. Carbohyd Polym, 68, 781-792
-
(2007)
Carbohyd Polym
, vol.68
, pp. 781-792
-
-
Yao, Z.1
Zhang, C.2
Ping, Q.N.3
Yu, L.4
-
33
-
-
57249084773
-
Polymeric micellar delivery systems in oncology
-
Yasuhiro, M. (2008). Polymeric micellar delivery systems in oncology, Jpn J Clin Oncol, 38, 793-802.
-
(2008)
Jpn J Clin Oncol
, vol.38
, pp. 793-802
-
-
Yasuhiro, M.1
-
34
-
-
38549150537
-
-
CHN Patent CN03132386.3
-
You, Q. D., Guo, Q. L., Ke, X., Xiao, W., Dai, L. L., and Lin, Y. (2003). The preparations of gambogic acid and its compound. CHN Patent CN03132386.3.
-
(2003)
The Preparations of Gambogic Acid and Its Compound
-
-
You, Q.D.1
Guo, Q.L.2
Ke, X.3
Xiao, W.4
Dai, L.L.5
Lin, Y.6
-
35
-
-
34047133853
-
Gambogic acid-induced G2/M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC-823 cells
-
Yu, J., Guo, Q. L., You, Q. D., Zhao, L., Gu, H. Y., Yang, Y., Zhang, H. W., Tan, Z., and Wang, X. (2007). Gambogic acid-induced G2/M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC-823 cells. Carcinogenesis, 28, 632-638
-
(2007)
Carcinogenesis
, vol.28
, pp. 632-638
-
-
Yu, J.1
Guo, Q.L.2
You, Q.D.3
Zhao, L.4
Gu, H.Y.5
Yang, Y.6
Zhang, H.W.7
Tan, Z.8
Wang, X.9
-
36
-
-
0041860927
-
Preparation of N-alkyl-O-sulfate chitosan derivatives and micellar solubilization of taxol
-
Zhang, C., Ping, Q. N., Zhang, H. G., and Shen, J. (2003). Preparation of N-alkyl-O-sulfate chitosan derivatives and micellar solubilization of taxol. Carbohyd Polym, 54, 137-141
-
(2003)
Carbohyd Polym
, vol.54
, pp. 137-141
-
-
Zhang, C.1
Ping, Q.N.2
Zhang, H.G.3
Shen, J.4
-
37
-
-
38349038224
-
Pharmacokinetics, biodistribution, efficacy and safety of N-octyl-O-sulfate chitosan micelles loaded with paclitaxel
-
Zhang, C., Qu, G. W., Sun, Y. J., Wu, X. L., Yao, Z., Guo, Q. L., Ding, Q. L., Yuan, S., Shen, Z. L., Ping, Q. N., and Zhou, H. P. (2008a). Pharmacokinetics, biodistribution, efficacy and safety of N-octyl-O-sulfate chitosan micelles loaded with paclitaxel. Biomaterials,29, 1233-1241
-
(2008)
Biomaterials
, vol.29
, pp. 1233-1241
-
-
Zhang, C.1
Qu, G.W.2
Sun, Y.J.3
Wu, X.L.4
Yao, Z.5
Guo, Q.L.6
Ding, Q.L.7
Yuan, S.8
Shen, Z.L.9
Ping, Q.N.10
Zhou, H.P.11
-
38
-
-
41349100022
-
Biological evaluation of N-octyl-O-sulfate chitosan as a new nano-carrier of intravenous drugs
-
Zhang, C., Qu, G. W., Sun, Y. J., Yang, T., Yao, Z., Shen, W. B., Shen, Z. L., Ding, Q. L., Zhou, H. P., and Ping, Q. N. (2008b). Biological evaluation of N-octyl-O-sulfate chitosan as a new nano-carrier of intravenous drugs. Eur J Pharm Sci, 33, 415-423
-
(2008)
Eur J Pharm Sci
, vol.33
, pp. 415-423
-
-
Zhang, C.1
Qu, G.W.2
Sun, Y.J.3
Yang, T.4
Yao, Z.5
Shen, W.B.6
Shen, Z.L.7
Ding, Q.L.8
Zhou, H.P.9
Ping, Q.N.10
-
39
-
-
0347320714
-
Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay
-
Zhang, H. Z., Kasibhatla, S., Wang, Y., Herich, J., Guastella, J., Tseng, B., Drewe, J., and Cai, S. X. (2004). Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay. Bioorg Med Chem Lett, 12, 309-317
-
(2004)
Bioorg Med Chem Lett
, vol.12
, pp. 309-317
-
-
Zhang, H.Z.1
Kasibhatla, S.2
Wang, Y.3
Herich, J.4
Guastella, J.5
Tseng, B.6
Drewe, J.7
Cai, S.X.8
-
41
-
-
9644266405
-
Gambogic acid induces apoptosis and regulates expressions of Bax and Bcl-2 protein in human gastric carcinoma MGC-803 cells
-
Zhao, L., Guo, Q. L., You, Q. D., Wu, Z. Q., and Gu, H. Y. (2004). Gambogic acid induces apoptosis and regulates expressions of Bax and Bcl-2 protein in human gastric carcinoma MGC-803 cells. Biol Pharm Bull, 27, 998-1003.
-
(2004)
Biol Pharm Bull
, vol.27
, pp. 998-1003
-
-
Zhao, L.1
Guo, Q.L.2
You, Q.D.3
Wu, Z.Q.4
Gu, H.Y.5
-
42
-
-
48049101768
-
Phase i human tolerability trail of gambogic acid
-
Zhou, Z. T., and Wang, J. W. (2007). Phase I human tolerability trail of gambogic acid. Chinese J New Drugs, 16, 79-83.
-
(2007)
Chinese J New Drugs
, vol.16
, pp. 79-83
-
-
Zhou, Z.T.1
Wang, J.W.2
-
43
-
-
38549092978
-
Preparation, physical properties, and stability of gambogic acidloaded micelles based on chitosan derivatives
-
Zhu, X., Zhang, C., Wu, X. L., Tang, X. Y., and Ping, Q. N. (2008). Preparation, physical properties, and stability of gambogic acidloaded micelles based on chitosan derivatives. Drug Dev Ind Pharm, 34, 2-9.
-
(2008)
Drug Dev Ind Pharm
, vol.34
, pp. 2-9
-
-
Zhu, X.1
Zhang, C.2
Wu, X.L.3
Tang, X.Y.4
Ping, Q.N.5
|