Role of human leukocyte antigen-G in the induction of adaptive type 1 regulatory T cells

Human Immunology

Volumn 70, Issue 12, 2009, Pages 966-969

  Gregori, Silvia ^a   Magnani, Chiara Francesca ^a   Roncarolo, Maria Grazia ^a,b  

^a SAN RAFFAELE SCIENTIFIC INSTITUTE   (Italy)

^b VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

Author keywords

HLA G; IL 10; Regulatory T cells; Tolerance; Tolerogenic DC; Type 1 regulatory T (Tr1) cells

Indexed keywords

ALPHA INTERFERON; HLA ANTIGEN CLASS 1; HLA G ANTIGEN; HLA G1 ANTIGEN; HLA G5 ANTIGEN; IMMUNOGLOBULIN; IMMUNOGLOBULIN LIKE TRANSCRIPT 4; INTERLEUKIN 10; UNCLASSIFIED DRUG;

ANTIGEN BINDING; ANTIGEN EXPRESSION; ARTICLE; CROSS REACTION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; ENZYME REGULATION; HUMAN; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANIMALS; DENDRITIC CELLS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; INTERLEUKIN-10; INTERLEUKIN-4; MEMBRANE GLYCOPROTEINS; PROTEIN ISOFORMS; RECEPTORS, IMMUNOLOGIC; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY;

EID: 70350728423     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2009.07.022     Document Type: Article

References (52)

1. Rouas-Freiss N., Goncalves R.M., Menier C., Dausset J., and Carosella E.D. Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis. Proc Natl Acad Sci USA 94 (1997) 11520-11525
2. Hunt J.S., Petroff M.G., McIntire R.H., and Ober C. HLA-G and immune tolerance in pregnancy. Faseb J 19 (2005) 681-693
3. Ishitani A., and Geraghty D.E. Alternative splicing of HLA-G transcripts yields proteins with primary structures resembling both class I and class II antigens. Proc Natl Acad Sci U S A 89 (1992) 3947-3951
4. Fujii T., Ishitani A., and Geraghty D.E. A soluble form of the HLA-G antigen is encoded by a messenger ribonucleic acid containing intron 4. J Immunol 153 (1994) 5516-5524
5. Moreau P., Rousseau P., Rouas-Freiss N., Le Discorde M., Dausset J., and Carosella E.D. HLA-G protein processing and transport to the cell surface. Cell Mol Life Sci 59 (2002) 1460-1466
6. Apps R., Gardner L., and Moffett A. A critical look at HLA-G. Trends Immunol 29 (2008) 313-321
7. Dong Y., Lieskovska J., Kedrin D., Porcelli S., Mandelboim O., and Bushkin Y. Soluble nonclassical HLA generated by the metalloproteinase pathway. Hum Immunol 64 (2003) 802-810
8. Ishitani A., Kishida M., Sageshima N., Yashiki S., Sonoda S., Hayami M., et al. Re-examination of HLA-G polymorphism in African Americans. Immunogenetics 49 (1999) 808-811
9. Bainbridge D.R., Ellis S.A., and Sargent I.L. Little evidence of HLA-G mRNA polymorphism in Caucasian or Afro-Caribbean populations. J Immunol 163 (1999) 2023-2027
10. Park B., Lee S., Kim E., Chang S., Jin M., and Ahn K. The truncated cytoplasmic tail of HLA-G serves a quality-control function in post-ER compartments. Immunity 15 (2001) 213-224
11. LeMaoult J., Le Discorde M., Rouas-Freiss N., Moreau P., Menier C., McCluskey J., et al. Biology and functions of human leukocyte antigen-G in health and sickness. Tissue Antigens 62 (2003) 273-284
12. Shiroishi M., Tsumoto K., Amano K., Shirakihara Y., Colonna M., Braud V.M., et al. Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G. Proc Natl Acad Sci U S A 100 (2003) 8856-8861
13. Rajagopalan S., and Long E.O. A human histocompatibility leukocyte antigen (HLA)-G-specific receptor expressed on all natural killer cells. J Exp Med 189 (1999) 1093-1100
14. Kapasi K., Albert S.E., Yie S., Zavazava N., and Librach C.L. HLA-G has a concentration-dependent effect on the generation of an allo-CTL response. Immunology 101 (2000) 191-200
15. Rouas-Freiss N., Marchal R.E., Kirszenbaum M., Dausset J., and Carosella E.D. The alpha1 domain of HLA-G1 and HLA-G2 inhibits cytotoxicity induced by natural killer cells: is HLA-G the public ligand for natural killer cell inhibitory receptors?. Proc Natl Acad Sci USA 94 (1997) 5249-5254
16. Pazmany L., Mandelboim O., Vales-Gomez M., Davis D.M., Reyburn H.T., and Strominger J.L. Protection from natural killer cell-mediated lysis by HLA-G expression on target cells. Science 274 (1996) 792-795
17. Le Gal F.A., Riteau B., Sedlik C., Khalil-Daher I., Menier C., Dausset J., et al. HLA-G-mediated inhibition of antigen-specific cytotoxic T lymphocytes. Int Immunol 11 (1999) 1351-1356
18. + T cell regulatory mechanism. Proc Natl Acad Sci USA 98 (2001) 12150-12155
19. Bainbridge D.R., Ellis S.A., and Sargent I.L. HLA-G suppresses proliferation of CD4(+) T-lymphocytes. J Reprod Immunol 48 (2000) 17-26
20. Horuzsko A., Lenfant F., Munn D.H., and Mellor A.L. Maturation of antigen-presenting cells is compromised in HLA-G transgenic mice. Int Immunol 13 (2001) 385-394
21. Liang S., Baibakov B., and Horuzsko A. HLA-G inhibits the functions of murine dendritic cells via the PIR-B immune inhibitory receptor. Eur J Immunol 32 (2002) 2418-2426
22. Liang S., and Horuzsko A. Mobilizing dendritic cells for tolerance by engagement of immune inhibitory receptors for HLA-G. Hum Immunol 64 (2003) 1025-1032
23. Sakaguchi S., Yamaguchi T., Nomura T., and Ono M. Regulatory T cells and immune tolerance. Cell 133 (2008) 775-787
24. + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 389 (1997) 737-742
25. Carosella E.D., HoWangYin K.Y., Favier B., and LeMaoult J. HLA-G-dependent suppressor cells: diverse by nature, function, and significance. Hum Immunol 69 (2008) 700-707
26. + T cells. Proc Natl Acad Sci USA 101 (2004) 7064-7069
27. low are induced by HLA-G: novel human peripheral blood suppressor T-cell subsets involved in transplant acceptance. Blood 110 (2007) 3936-3948
28. Feger U., Tolosa E., Huang Y.H., Waschbisch A., Biedermann T., Meims A., et al. HLA-G expression defines a novel regulatory T-cell subset present in human peripheral blood and sites of inflammation. Blood 110 (2007) 568-577
29. + T cells is IL-10-dependent and reversible. J Leukoc Biol 86 2 (2009) 273-281
30. Ristich V., Liang S., Zhang W., Wu J., and Horuzsko A. Tolerization of dendritic cells by HLA-G. Eur J Immunol 35 (2005) 1133-1142
31. Ristich V., Zhang W., Liang S., and Horuzsko A. Mechanisms of prolongation of allograft survival by HLA-G/ILT4-modified dendritic cells. Hum Immunol 68 (2007) 264-271
32. + regulatory T cells. Stem Cells 26 (2008) 212-222
33. Moreau P., Adrian-Cabestre F., Menier C., Guiard V., Gourand L., Dausset J., et al. IL-10 selectively induces HLA-G expression in human trophoblasts and monocytes. Int Immunol 11 (1999) 803-811
34. + tolerogenic endothelial cells in organ allografts. Transpl Immunol 13 (2004) 73-82
35. Vlad G., Piazza F., Colovai A., Cortesini R., Della Pietra F., Suciu-Foca N., et al. Interleukin-10 induces the upregulation of the inhibitory receptor ILT4 in monocytes from HIV positive individuals. Hum Immunol 64 (2003) 483-489
36. Battaglia M., Stabilini A., Draghici E., Gregori S., Mocchetti C., Bonifacio E., et al. Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance. Diabetes 55 (2006) 40-49
37. Roncarolo M.G., Gregori S., Battaglia M., Bacchetta R., Fleischhauer K., and Levings M.K. Interleukin-10-secreting type 1 regulatory T cells in rodents and humans. Immunol Rev 212 (2006) 28-50
38. Levings M.K., Sangregorio R., Galbiati F., Squadrone S., de Waal Malefyt R., and Roncarolo M.G. IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells. J Immunol 166 (2001) 5530-5539
39. Wakkach A., Cottrez F., and Groux H. Differentiation of regulatory T cells 1 is induced by CD2 costimulation. J Immunol 167 (2001) 3107-3113
40. Ito T., Yang M., Wang Y.H., Lande R., Gregorio J., Perng O.A., et al. Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand. J Exp Med 204 (2007) 105-115
41. + cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype. Nature 421 (2003) 388-392
42. + T cells by streptococcal M protein. J Immunol 175 (2005) 677-684
43. Morelli A.E., and Thomson A.W. Tolerogenic dendritic cells and the quest for transplant tolerance. Nat Rev Immunol 7 (2007) 610-621
44. + Tr cells. Blood 105 (2005) 1162-1169
45. Jonuleit H., Schmitt E., Schuler G., Knop J., and Enk A.H. Induction of interleukin 10- producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med 192 (2000) 1213-1222
46. Colonna M., Samaridis J., Cella M., Angman L., Allen R.L., O'Callaghan C.A., et al. Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules. J Immunol 160 (1998) 3096-3100
47. Liang S., Ristich V., Arase H., Dausset J., Carosella E.D., and Horuzsko A. Modulation of dendritic cell differentiation by HLA-G and ILT4 requires the IL-6-STAT3 signaling pathway. Proc Natl Acad Sci USA 105 (2008) 8357-8362
48. Comiskey M., Domino K.E., and Warner C.M. HLA-G is found in lipid rafts and can act as a signaling molecule. Hum Immunol 68 (2007) 1-11
49. Le Rond S., Azema C., Krawice-Radanne I., Durrbach A., Guettier C., Carosella E.D., et al. Evidence to support the role of HLA-G5 in allograft acceptance through induction of immunosuppressive/regulatory T cells. J Immunol 176 (2006) 3266-3276
50. Le Maux A., Noel G., Birebent B., Grosset J.M., Vu N., De Guibert S., et al. Soluble human leucocyte antigen-G molecules in peripheral blood haematopoietic stem cell transplantation: a specific role to prevent acute graft-versus-host disease and a link with regulatory T cells. Clin Exp Immunol 152 (2008) 50-56
51. Naji A., Durrbach A., Carosella E.D., and Rouas-Freiss N. Soluble HLA-G and HLA-G1 expressing antigen-presenting cells inhibit T-cell alloproliferation through ILT-2/ILT-4/FasL-mediated pathways. Hum Immunol 68 (2007) 233-239
52. Gonen-Gross T., and Mandelboim O. HLA-G complexes are observed on the cell surface. Hum Immunol 68 (2007) 227-232