HLA-G Complexes Are Observed on the Cell Surface

Human Immunology

Volumn 68, Issue 4, 2007, Pages 227-232

  Gonen Gross, Tsufit ^a   Mandelboim, Ofer ^a  

^a HEBREW UNIVERSITY   (Israel)

Author keywords

HLA G; LIR 1; NK

Indexed keywords

HLA G ANTIGEN; LEUKOCYTE IMMUNOGLOBULIN LIKE RECEPTOR 1; LYMPHOCYTE ANTIGEN RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MEMBRANE ANTIGEN; UNCLASSIFIED DRUG;

ARTICLE; CELL SURFACE; COMPLEX FORMATION; HLA SYSTEM; HUMAN; HUMAN CELL; IMMUNOMODULATION; MAJOR HISTOCOMPATIBILITY COMPLEX; PREGNANCY; PRIORITY JOURNAL;

CELL LINE, TRANSFORMED; CELL LINE, TUMOR; CELL MEMBRANE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS;

EID: 33947614147     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2006.10.013     Document Type: Article

References (20)

1. O'Callaghan C.A., and Bell J.I. Structure and function of the human MHC class Ib molecules HLA-E, HLA-F and HLA-G. Immunol Rev 163 (1998) 129
2. Redman C.W., McMichael A.J., Stirrat G.M., Sunderland C.A., and Ting A. Class 1 major histocompatibility complex antigens on human extra-villous trophoblast. Immunology 52 (1984) 457
3. McMaster M.T., Librach C.L., Zhou Y., Lim K.H., Janatpour M.J., DeMars R., Kovats S., Damsky C., and Fisher S.J. Human placental HLA-G expression is restricted to differentiated cytotrophoblasts. J Immunol 154 (1995) 3771
4. Hviid T.V. HLA-G in human reproduction: aspects of genetics, function and pregnancy complications. Hum Reprod Update 12 (2006) 209
5. Hunt J.S., Petroff M.G., McIntire R.H., and Ober C. HLA-G and immune tolerance in pregnancy. Faseb J 19 (2005) 681
6. Moffett-King A., Entrican G., Ellis S., Hutchinson J., and Bainbridge D. Natural killer cells and reproduction. Trends Immunol 23 (2002) 332
7. Gonen-Gross T., Achdout H., Gazit R., Hanna J., Mizrahi S., Markel G., Goldman-Wohl D., Yagel S., Horejsi V., Levy O., Baniyash M., and Mandelboim O. Complexes of HLA-G protein on the cell surface are important for leukocyte Ig-like receptor-1 function. J Immunol 171 (2003) 1343
8. Gonen-Gross T., Achdout H., Arnon T.I., Gazit R., Stern N., Horejsi V., Goldman-Wohl D., Yagel S., and Mandelboim O. The CD85J/leukocyte inhibitory receptor-1 distinguishes between conformed and beta 2-microglobulin-free HLA-G molecules. J Immunol 175 (2005) 4866
9. Gonen-Gross T., Gazit R., Achdout H., Hanna J., Mizrahi S., Markel G., Horejsi V., and Mandelboim O. Special organization of the HLA-G protein on the cell surface. Hum Immunol 64 (2003) 1011
10. Shiroishi M., Kuroki K., Ose T., Rasubala L., Shiratori I., Arase H., Tsumoto K., Kumagai I., Kohda D., and Maenaka K. Efficient leukocyte Ig-like receptor signaling and crystal structure of disulfide-linked HLA-G dimer. J Biol Chem 281 (2006) 10439
11. Restifo N.P., Marincola F.M., Kawakami Y., Taubenberger J., Yannelli J.R., and Rosenberg S.A. Loss of functional beta 2-microglobulin in metastatic melanomas from five patients receiving immunotherapy. J Natl Cancer Inst 88 (1996) 100
12. Porgador A., Mandelboim O., Restifo N.P., and Strominger J.L. Natural killer cell lines kill autologous beta2-microglobulin-deficient melanoma cells: implications for cancer immunotherapy. Proc Natl Acad Sci U S A 94 (1997) 13140
13. Mandelboim O., Reyburn H.T., Vales-Gomez M., Pazmany L., Colonna M., Borsellino G., and Strominger J.L. Protection from lysis by natural killer cells of group 1 and 2 specificity is mediated by residue 80 in human histocompatibility leukocyte antigen C alleles and also occurs with empty major histocompatibility complex molecules. J Exp Med 184 (1996) 913
14. Geraghty D.E., Koller B.H., and Orr H.T. A human major histocompatibility complex class I gene that encodes a protein with a shortened cytoplasmic segment. Proc Natl Acad Sci U S A 84 (1987) 9145
15. Kovats S., Main E.K., Librach C., Stubblebine M., Fisher S.J., and DeMars R. A class I antigen, HLA-G, expressed in human trophoblasts. Science 248 (1990) 220
16. Grandea III A.G., Lehner P.J., Cresswell P., and Spies T. Regulation of MHC class I heterodimer stability and interaction with TAP by tapasin. Immunogenetics 46 (1997) 477
17. Bird L.A., Peh C.A., Kollnberger S., Elliott T., McMichael A.J., and Bowness P. Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling. Eur J Immunol 33 (2003) 748
18. Davis D.M., Reyburn H.T., Pazmany L., Chiu I., Mandelboim O., and Strominger J.L. Impaired spontaneous endocytosis of HLA-G. Eur J Immunol 27 (1997) 2714
19. Allen R.L., Bowness P., and McMichael A. The role of HLA-B27 in spondyloarthritis. Immunogenetics 50 (1999) 220
20. Rajagopalan S., Bryceson Y.T., Kuppusamy S.P., Geraghty D.E., van der Meer A., Joosten I., and Long E.O. Activation of NK cells by an endocytosed receptor for soluble HLA-G. PLoS Biol 4 (2006) e9