-
1
-
-
12844281837
-
The proteasome
-
Dalton W.S. The proteasome. Semin Oncol 31 (2004) 3-9
-
(2004)
Semin Oncol
, vol.31
, pp. 3-9
-
-
Dalton, W.S.1
-
2
-
-
27144526164
-
Orchestra for assembly and fate of polyubiquitin chains
-
Kuhlbrodt K., Mouysset J., and Hoppe T. Orchestra for assembly and fate of polyubiquitin chains. Essays Biochem 41 (2005) 1-14
-
(2005)
Essays Biochem
, vol.41
, pp. 1-14
-
-
Kuhlbrodt, K.1
Mouysset, J.2
Hoppe, T.3
-
3
-
-
0034915764
-
Mechanisms underlying ubiquitination
-
Pickart C.M. Mechanisms underlying ubiquitination. Annu Rev Biochem 70 (2001) 503-533
-
(2001)
Annu Rev Biochem
, vol.70
, pp. 503-533
-
-
Pickart, C.M.1
-
4
-
-
28344456279
-
A genomic and functional inventory of deubiquitinating enzymes
-
Nijman S.M., Luna-Vargas M.P., Velds A., et al. A genomic and functional inventory of deubiquitinating enzymes. Cell 123 (2005) 773-786
-
(2005)
Cell
, vol.123
, pp. 773-786
-
-
Nijman, S.M.1
Luna-Vargas, M.P.2
Velds, A.3
-
5
-
-
16244373679
-
Multiubiquitylation by E4 enzymes: 'one size' doesn't fit all
-
Hoppe T. Multiubiquitylation by E4 enzymes: 'one size' doesn't fit all. Trends Biochem Sci 30 (2005) 183-187
-
(2005)
Trends Biochem Sci
, vol.30
, pp. 183-187
-
-
Hoppe, T.1
-
6
-
-
33947312840
-
Ubiquitylation within signaling pathways in- and outside of inflammation
-
Hochrainer K., and Lipp J. Ubiquitylation within signaling pathways in- and outside of inflammation. Thromb Haemost 97 (2007) 370-377
-
(2007)
Thromb Haemost
, vol.97
, pp. 370-377
-
-
Hochrainer, K.1
Lipp, J.2
-
7
-
-
33947380146
-
Mass spectrometric characterization of the affinity-purified human 26S proteasome complex
-
Wang X., Chen C.F., Baker P.R., Chen P.L., Kaiser P., and Huang L. Mass spectrometric characterization of the affinity-purified human 26S proteasome complex. Biochemistry 46 (2007) 3553-3565
-
(2007)
Biochemistry
, vol.46
, pp. 3553-3565
-
-
Wang, X.1
Chen, C.F.2
Baker, P.R.3
Chen, P.L.4
Kaiser, P.5
Huang, L.6
-
8
-
-
33845681479
-
Cooperation of multiple chaperones required for the assembly of mammalian 20S proteasomes
-
Hirano Y., Hayashi H., Iemura S., et al. Cooperation of multiple chaperones required for the assembly of mammalian 20S proteasomes. Mol Cell 24 (2006) 977-984
-
(2006)
Mol Cell
, vol.24
, pp. 977-984
-
-
Hirano, Y.1
Hayashi, H.2
Iemura, S.3
-
9
-
-
0033766480
-
A gated channel into the proteasome core particle
-
Groll M., Bajorek M., Kohler A., et al. A gated channel into the proteasome core particle. Nat Struct Biol 7 (2000) 1062-1067
-
(2000)
Nat Struct Biol
, vol.7
, pp. 1062-1067
-
-
Groll, M.1
Bajorek, M.2
Kohler, A.3
-
10
-
-
11844287006
-
Mobilizing the proteolytic machine: cell biological roles of proteasome activators and inhibitors
-
Rechsteiner M., and Hill C.P. Mobilizing the proteolytic machine: cell biological roles of proteasome activators and inhibitors. Trends Cell Biol 15 (2005) 27-33
-
(2005)
Trends Cell Biol
, vol.15
, pp. 27-33
-
-
Rechsteiner, M.1
Hill, C.P.2
-
11
-
-
27644563785
-
Purification of PA700, the 19S regulatory complex of the 26S proteasome
-
DeMartino G.N. Purification of PA700, the 19S regulatory complex of the 26S proteasome. Methods Enzymol 398 (2005) 295-306
-
(2005)
Methods Enzymol
, vol.398
, pp. 295-306
-
-
DeMartino, G.N.1
-
12
-
-
0035892754
-
Immunoproteasomes largely replace constitutive proteasomes during an antiviral and antibacterial immune response in the liver
-
Khan S., van den Broek M., Schwarz K., de Giuli R., Diener P.A., and Groettrup M. Immunoproteasomes largely replace constitutive proteasomes during an antiviral and antibacterial immune response in the liver. J Immunol 167 (2001) 6859-6868
-
(2001)
J Immunol
, vol.167
, pp. 6859-6868
-
-
Khan, S.1
van den Broek, M.2
Schwarz, K.3
de Giuli, R.4
Diener, P.A.5
Groettrup, M.6
-
13
-
-
0036646488
-
PA200, a nuclear proteasome activator involved in DNA repair
-
Ustrell V., Hoffmann L., Pratt G., and Rechsteiner M. PA200, a nuclear proteasome activator involved in DNA repair. EMBO J 21 (2003) 3516-3525
-
(2003)
EMBO J
, vol.21
, pp. 3516-3525
-
-
Ustrell, V.1
Hoffmann, L.2
Pratt, G.3
Rechsteiner, M.4
-
14
-
-
0034640520
-
Hybrid proteasomes: induction by interferon-γ and contribution to ATP-dependent proteolysis
-
Tanahashi N., Murakami Y., Minami Y., Shimbara N., Hendil K.B., and Tanaka K. Hybrid proteasomes: induction by interferon-γ and contribution to ATP-dependent proteolysis. J Biol Chem 275 (2000) 14336-14345
-
(2000)
J Biol Chem
, vol.275
, pp. 14336-14345
-
-
Tanahashi, N.1
Murakami, Y.2
Minami, Y.3
Shimbara, N.4
Hendil, K.B.5
Tanaka, K.6
-
15
-
-
26844453345
-
Perspectives for combination therapy to overcome drug-resistant multiple myeloma
-
Catley L., Tai Y.T., Chauhan D., and Anderson K.C. Perspectives for combination therapy to overcome drug-resistant multiple myeloma. Drug Res Updates 8 (2005) 205-218
-
(2005)
Drug Res Updates
, vol.8
, pp. 205-218
-
-
Catley, L.1
Tai, Y.T.2
Chauhan, D.3
Anderson, K.C.4
-
16
-
-
20444433230
-
Bortezomib or high-dose dexamethasone for relapsed multiple myeloma
-
Richardson P.G., Sonneveld P., Schuster M.W., et al. Bortezomib or high-dose dexamethasone for relapsed multiple myeloma. N Engl J Med 352 (2005) 2487-2498
-
(2005)
N Engl J Med
, vol.352
, pp. 2487-2498
-
-
Richardson, P.G.1
Sonneveld, P.2
Schuster, M.W.3
-
17
-
-
20044396543
-
Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma
-
Goy A., Younes A., McLaughlin P., et al. Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma. J Clin Oncol 23 (2005) 667-675
-
(2005)
J Clin Oncol
, vol.23
, pp. 667-675
-
-
Goy, A.1
Younes, A.2
McLaughlin, P.3
-
18
-
-
33644824608
-
Altering protein turnover in tumor cells: new opportunities for anti-cancer therapies
-
Demarchi F., and Brancolini C. Altering protein turnover in tumor cells: new opportunities for anti-cancer therapies. Drug Res Updates 8 (2005) 359-368
-
(2005)
Drug Res Updates
, vol.8
, pp. 359-368
-
-
Demarchi, F.1
Brancolini, C.2
-
19
-
-
30644466383
-
Targeting the proteasome in mantle cell lymphoma: a promising therapeutic approach
-
Bogner C., Peschel C., and Decker T. Targeting the proteasome in mantle cell lymphoma: a promising therapeutic approach. Leuk Lymphoma 47 (2006) 195-205
-
(2006)
Leuk Lymphoma
, vol.47
, pp. 195-205
-
-
Bogner, C.1
Peschel, C.2
Decker, T.3
-
20
-
-
34247125164
-
The proteasome: a worthwhile target for the treatment of solid tumours?
-
Milano A., Iaffaioli R.V., and Caponigro F. The proteasome: a worthwhile target for the treatment of solid tumours?. Eur J Cancer 43 (2007) 1125-1133
-
(2007)
Eur J Cancer
, vol.43
, pp. 1125-1133
-
-
Milano, A.1
Iaffaioli, R.V.2
Caponigro, F.3
-
21
-
-
0035328584
-
Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition
-
Cusack J.C., Liu R., Houston M., et al. Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition. Cancer Res 61 (2001) 3535-3540
-
(2001)
Cancer Res
, vol.61
, pp. 3535-3540
-
-
Cusack, J.C.1
Liu, R.2
Houston, M.3
-
22
-
-
0035341494
-
Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-κB
-
Russo S.M., Tepper J.E., Baldwin A.S., et al. Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-κB. Int J Radiat Oncol Biol Phys 50 (2001) 183-193
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.50
, pp. 183-193
-
-
Russo, S.M.1
Tepper, J.E.2
Baldwin, A.S.3
-
23
-
-
0037342894
-
The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents
-
Ma M.H., Yang H.H., Parker K., et al. The proteasome inhibitor PS-341 markedly enhances sensitivity of multiple myeloma tumor cells to chemotherapeutic agents. Clin Cancer Res 9 (2003) 1136-1144
-
(2003)
Clin Cancer Res
, vol.9
, pp. 1136-1144
-
-
Ma, M.H.1
Yang, H.H.2
Parker, K.3
-
24
-
-
0037443551
-
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications
-
Mitsiades N., Mitsiades C.S., Richardson P.G., et al. The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications. Blood 101 (2003) 2377-2380
-
(2003)
Blood
, vol.101
, pp. 2377-2380
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Richardson, P.G.3
-
25
-
-
24944526723
-
Phase I trial of bortezomib and carboplatin in recurrent ovarian or primary peritoneal cancer
-
Aghajanian C., Dizon D.S., Sabbatini P., Raizer J.J., Dupont J., and Spriggs D.R. Phase I trial of bortezomib and carboplatin in recurrent ovarian or primary peritoneal cancer. J Clin Oncol 23 (2005) 5943-5949
-
(2005)
J Clin Oncol
, vol.23
, pp. 5943-5949
-
-
Aghajanian, C.1
Dizon, D.S.2
Sabbatini, P.3
Raizer, J.J.4
Dupont, J.5
Spriggs, D.R.6
-
26
-
-
20144387627
-
Phase I trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies
-
Orlowski R.Z., Voorhees P.M., Garcia R.A., et al. Phase I trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies. Blood 105 (2005) 3058-3065
-
(2005)
Blood
, vol.105
, pp. 3058-3065
-
-
Orlowski, R.Z.1
Voorhees, P.M.2
Garcia, R.A.3
-
27
-
-
33745801771
-
Bortezomib in combination with dexamethasone for the treatment of patients with relapsed and/or refractory multiple myeloma with less than optimal response to bortezomib alone
-
Jagannath S., Richardson P.G., Barlogie B., et al. Bortezomib in combination with dexamethasone for the treatment of patients with relapsed and/or refractory multiple myeloma with less than optimal response to bortezomib alone. Haematologica 91 (2006) 929-934
-
(2006)
Haematologica
, vol.91
, pp. 929-934
-
-
Jagannath, S.1
Richardson, P.G.2
Barlogie, B.3
-
28
-
-
0029144249
-
A K-252a-resistance gene, sks1+, encodes a protein similar to the Caenorhabditis elegans F37 A45 gene product and confers multidrug resistance in Schizosaccharomyces pombe
-
Usui T., Yoshida M., Honda A., Beppu T., and Horinouchi S. A K-252a-resistance gene, sks1+, encodes a protein similar to the Caenorhabditis elegans F37 A45 gene product and confers multidrug resistance in Schizosaccharomyces pombe. Gene 161 (1995) 93-96
-
(1995)
Gene
, vol.161
, pp. 93-96
-
-
Usui, T.1
Yoshida, M.2
Honda, A.3
Beppu, T.4
Horinouchi, S.5
-
29
-
-
0028957971
-
bfr1+, a novel gene of Schizosaccharomyces pombe which confers brefeldin A resistance, is structurally related to the ATP-binding cassette superfamily
-
Nagao K., Taguchi Y., Arioka M., et al. bfr1+, a novel gene of Schizosaccharomyces pombe which confers brefeldin A resistance, is structurally related to the ATP-binding cassette superfamily. J Bacteriol 177 (1995) 1536-1543
-
(1995)
J Bacteriol
, vol.177
, pp. 1536-1543
-
-
Nagao, K.1
Taguchi, Y.2
Arioka, M.3
-
30
-
-
0031989752
-
Multidrug resistance phenotype conferred by over-expressing bfr2+/pad1+/sks1+ or pap1+ genes and mediated by bfr1+ gene product, a structural and functional homologue of P-glycoprotein in Schizosaccharomyces pombe
-
Arioka M., Kouhashi M., Yoda K., Takatsuki A., Yamasaki M., and Kitamoto K. Multidrug resistance phenotype conferred by over-expressing bfr2+/pad1+/sks1+ or pap1+ genes and mediated by bfr1+ gene product, a structural and functional homologue of P-glycoprotein in Schizosaccharomyces pombe. Biosci Biotechnol Biochem 62 (1998) 390-392
-
(1998)
Biosci Biotechnol Biochem
, vol.62
, pp. 390-392
-
-
Arioka, M.1
Kouhashi, M.2
Yoda, K.3
Takatsuki, A.4
Yamasaki, M.5
Kitamoto, K.6
-
31
-
-
0028898060
-
A novel essential fission yeast gene pad1+ positively regulates pap1+-dependent transcription and is implicated in the maintenance of chromosome structure
-
Shimanuki M., Saka Y., Yanagida M., and Toda T. A novel essential fission yeast gene pad1+ positively regulates pap1+-dependent transcription and is implicated in the maintenance of chromosome structure. J Cell Sci 108 (1995) 569-579
-
(1995)
J Cell Sci
, vol.108
, pp. 569-579
-
-
Shimanuki, M.1
Saka, Y.2
Yanagida, M.3
Toda, T.4
-
32
-
-
0026681291
-
Alterations in a yeast protein resembling HIV Tat-binding protein relieve requirement for acidic activation domain in GAL4
-
Swaffield J.C., Bromberg J.F., and Johnston S.A. Alterations in a yeast protein resembling HIV Tat-binding protein relieve requirement for acidic activation domain in GAL4. Nature 357 (1992) 698-700
-
(1992)
Nature
, vol.357
, pp. 698-700
-
-
Swaffield, J.C.1
Bromberg, J.F.2
Johnston, S.A.3
-
33
-
-
0028901715
-
cDNA cloning of a new putative ATPase subunit p45 of the human 26S proteasome, a homolog of yeast transcriptional factor Sug1p
-
Akiyama K., Yokota K., Kagawa S., et al. cDNA cloning of a new putative ATPase subunit p45 of the human 26S proteasome, a homolog of yeast transcriptional factor Sug1p. FEBS Lett 363 (1995) 151-156
-
(1995)
FEBS Lett
, vol.363
, pp. 151-156
-
-
Akiyama, K.1
Yokota, K.2
Kagawa, S.3
-
34
-
-
0030061512
-
Identification of the gal4 suppressor Sug1 as a subunit of the yeast 26S proteasome
-
Rubin D.M., Coux O., Wefes I., et al. Identification of the gal4 suppressor Sug1 as a subunit of the yeast 26S proteasome. Nature 379 (1996) 655-657
-
(1996)
Nature
, vol.379
, pp. 655-657
-
-
Rubin, D.M.1
Coux, O.2
Wefes, I.3
-
35
-
-
0029739021
-
Mammalian Sug1 and c-Fos in the nuclear 26S proteasome
-
Wang W., Chevray P.M., and Nathans D. Mammalian Sug1 and c-Fos in the nuclear 26S proteasome. Proc Natl Acad Sci USA 93 (1996) 8236-8240
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8236-8240
-
-
Wang, W.1
Chevray, P.M.2
Nathans, D.3
-
36
-
-
0012316186
-
Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1
-
vom Baur E., Zechel C., Heery D., et al. Differential ligand-dependent interactions between the AF-2 activating domain of nuclear receptors and the putative transcriptional intermediary factors mSUG1 and TIF1. EMBO J 15 (1996) 110-124
-
(1996)
EMBO J
, vol.15
, pp. 110-124
-
-
vom Baur, E.1
Zechel, C.2
Heery, D.3
-
37
-
-
0030728770
-
Resistance to diverse drugs and ultraviolet light conferred by overexpression of a novel human 26S proteasome subunit
-
Spataro V., Toda T., Craig R., et al. Resistance to diverse drugs and ultraviolet light conferred by overexpression of a novel human 26S proteasome subunit. J Biol Chem 272 (1997) 30470-30475
-
(1997)
J Biol Chem
, vol.272
, pp. 30470-30475
-
-
Spataro, V.1
Toda, T.2
Craig, R.3
-
38
-
-
0027466870
-
Phenobarbital induction of AP-1 binding activity mediates activation of glutathione S-transferase and quinine reductase gene expression
-
Pinkus R., Bergelson S., and Danial V. Phenobarbital induction of AP-1 binding activity mediates activation of glutathione S-transferase and quinine reductase gene expression. Biochem J 290 (1993) 637-640
-
(1993)
Biochem J
, vol.290
, pp. 637-640
-
-
Pinkus, R.1
Bergelson, S.2
Danial, V.3
-
39
-
-
0028291078
-
Involvement of Jun and Fos proteins in regulating transcriptional activation of the human pi class glutathione S-transferase gene in multidrug-resistant MCF7 breast cancer cells
-
Moffat G.J., McLaren A.W., and Wold C.R. Involvement of Jun and Fos proteins in regulating transcriptional activation of the human pi class glutathione S-transferase gene in multidrug-resistant MCF7 breast cancer cells. J Biol Chem 269 (1994) 16397-16402
-
(1994)
J Biol Chem
, vol.269
, pp. 16397-16402
-
-
Moffat, G.J.1
McLaren, A.W.2
Wold, C.R.3
-
40
-
-
0028136347
-
Increased c-jun/AP-1 levels in etoposide-resistant human leukaemia K562 cells
-
Ritke M.K., Bergoltz V.V., Allan W.P., and Yalowich J.C. Increased c-jun/AP-1 levels in etoposide-resistant human leukaemia K562 cells. Biochem Pharmacol 48 (1994) 525-533
-
(1994)
Biochem Pharmacol
, vol.48
, pp. 525-533
-
-
Ritke, M.K.1
Bergoltz, V.V.2
Allan, W.P.3
Yalowich, J.C.4
-
41
-
-
0029052835
-
Evidence for altered regulation of γ-glutamylcysteine synthetase gene expression among cisplatin-sensitive and cisplatin-resistant human ovarian cancer cell lines
-
Yao K.S., Godwin A.K., Johnson S.W., Ozols R.F., O'Dwyer P.J., and Hamilton T.C. Evidence for altered regulation of γ-glutamylcysteine synthetase gene expression among cisplatin-sensitive and cisplatin-resistant human ovarian cancer cell lines. Cancer Res 55 (1995) 4367-4374
-
(1995)
Cancer Res
, vol.55
, pp. 4367-4374
-
-
Yao, K.S.1
Godwin, A.K.2
Johnson, S.W.3
Ozols, R.F.4
O'Dwyer, P.J.5
Hamilton, T.C.6
-
42
-
-
0036875582
-
The essential 26S proteasome subunit Rpn11 confers multidrug resistance to mammalian cells
-
Spataro V., Simmen K., and Realini C.A. The essential 26S proteasome subunit Rpn11 confers multidrug resistance to mammalian cells. Anticancer Res 22 (2002) 3905-3910
-
(2002)
Anticancer Res
, vol.22
, pp. 3905-3910
-
-
Spataro, V.1
Simmen, K.2
Realini, C.A.3
-
43
-
-
0036724625
-
Chk2 is a tumour suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner
-
Hirao A., Cheung A., Duncan G., et al. Chk2 is a tumour suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner. Mol Cell Biol 22 (2002) 6521-6532
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6521-6532
-
-
Hirao, A.1
Cheung, A.2
Duncan, G.3
-
44
-
-
13444310626
-
Inducible degradation of checkpoint kinase 2 links to cisplatin-induced resistance in ovarian cancer cells
-
Zhang P., Gao W., Li H., Reed E., and Chen F. Inducible degradation of checkpoint kinase 2 links to cisplatin-induced resistance in ovarian cancer cells. Biochem Biophys Res Commun 328 (2005) 567-572
-
(2005)
Biochem Biophys Res Commun
, vol.328
, pp. 567-572
-
-
Zhang, P.1
Gao, W.2
Li, H.3
Reed, E.4
Chen, F.5
-
45
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt Y., Maya R., Kazaz A., and Oren M. Mdm2 promotes the rapid degradation of p53. Nature 387 (1997) 296-299
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
46
-
-
0034635952
-
Bax degradation by the ubiquitin/proteasome pathway: involvement in tumour survival and progression
-
Li B., and Dou Q.P. Bax degradation by the ubiquitin/proteasome pathway: involvement in tumour survival and progression. Proc Natl Acad Sci USA 97 (2000) 3850-3855
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 3850-3855
-
-
Li, B.1
Dou, Q.P.2
-
47
-
-
0035284812
-
Proteasomes modulate balance among pro-apoptotic and anti apoptotic Bcl-2 family members and compromise functioning of the electron transport chain in leukemic cells
-
Marshansky V., Wang X., Bertrand R., et al. Proteasomes modulate balance among pro-apoptotic and anti apoptotic Bcl-2 family members and compromise functioning of the electron transport chain in leukemic cells. J Immunol 166 (2001) 3130-3142
-
(2001)
J Immunol
, vol.166
, pp. 3130-3142
-
-
Marshansky, V.1
Wang, X.2
Bertrand, R.3
-
48
-
-
0034647563
-
Ubiquitin-mediated degradation of the proapoptotic active form of bid. A functional consequence on apoptosis induction
-
Breitschopf K., Zeiher A.M., and Dimmeler S. Ubiquitin-mediated degradation of the proapoptotic active form of bid. A functional consequence on apoptosis induction. J Biol Chem 275 (2000) 21648-21652
-
(2000)
J Biol Chem
, vol.275
, pp. 21648-21652
-
-
Breitschopf, K.1
Zeiher, A.M.2
Dimmeler, S.3
-
49
-
-
0034282432
-
The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7
-
Huang H., Joazeiro C.A., Bonfocco E., Kamada S., Leverson J.D., and Hunter T. The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7. J Biol Chem 275 (2000) 26661-26664
-
(2000)
J Biol Chem
, vol.275
, pp. 26661-26664
-
-
Huang, H.1
Joazeiro, C.A.2
Bonfocco, E.3
Kamada, S.4
Leverson, J.D.5
Hunter, T.6
-
50
-
-
0035902601
-
Ubiquitin-protein ligase activity of x-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect if Fas-induced cell death
-
Suzuki Y., Nakabayashi Y., and Takahashi R. Ubiquitin-protein ligase activity of x-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect if Fas-induced cell death. Proc Natl Acad Sci USA 98 (2001) 8662-8667
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8662-8667
-
-
Suzuki, Y.1
Nakabayashi, Y.2
Takahashi, R.3
-
51
-
-
0034084163
-
Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity
-
Karin M., and Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. Annu Rev Immunol 18 (2000) 621-663
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
52
-
-
4444300254
-
Inhibition of constitutively activated nuclear factor-κB radiosensitizes human melanoma cells
-
Munshi A., Kurland J.F., Nishikawa T., Chiao P.J., Andreeff M., and Meyn R.E. Inhibition of constitutively activated nuclear factor-κB radiosensitizes human melanoma cells. Mol Cancer Ther 3 (2004) 985-992
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 985-992
-
-
Munshi, A.1
Kurland, J.F.2
Nishikawa, T.3
Chiao, P.J.4
Andreeff, M.5
Meyn, R.E.6
-
53
-
-
23944490171
-
Proteases, proteasomes and apoptosis: breaking Ub is hard to do
-
Taylor R.C., Adrian C., and Martin S.J. Proteases, proteasomes and apoptosis: breaking Ub is hard to do. Cell Death Differ 12 (2005) 1213-1217
-
(2005)
Cell Death Differ
, vol.12
, pp. 1213-1217
-
-
Taylor, R.C.1
Adrian, C.2
Martin, S.J.3
-
54
-
-
0033772765
-
Regulatory networks revealed by transcriptional profiling of damaged Saccharomyces cerevisiae cells: Rpn4 links with base excision repair with proteasomes
-
Jelinsky S.A., Estep P., Church G.M., and Samson L.D. Regulatory networks revealed by transcriptional profiling of damaged Saccharomyces cerevisiae cells: Rpn4 links with base excision repair with proteasomes. Mol Cell Biol 20 (2000) 8157-8167
-
(2000)
Mol Cell Biol
, vol.20
, pp. 8157-8167
-
-
Jelinsky, S.A.1
Estep, P.2
Church, G.M.3
Samson, L.D.4
-
55
-
-
0031016683
-
Incubation at the nonpermissive temperature induces deficiencies in UV resistance and mutagenesis in mouse mutant cells expressing a temperature-sensitive ubiquitin-activating enzyme (E1)
-
Ikehata H., Kaneda S., Yamao F., Seno T., Ono T., and Hanaoka F. Incubation at the nonpermissive temperature induces deficiencies in UV resistance and mutagenesis in mouse mutant cells expressing a temperature-sensitive ubiquitin-activating enzyme (E1). Mol Cell Biol 17 (1997) 1484-1489
-
(1997)
Mol Cell Biol
, vol.17
, pp. 1484-1489
-
-
Ikehata, H.1
Kaneda, S.2
Yamao, F.3
Seno, T.4
Ono, T.5
Hanaoka, F.6
-
56
-
-
0023236126
-
The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme
-
Jentsch S., McGrath J.P., and Varshavsky A. The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme. Nature 329 (1987) 131-134
-
(1987)
Nature
, vol.329
, pp. 131-134
-
-
Jentsch, S.1
McGrath, J.P.2
Varshavsky, A.3
-
57
-
-
2442649167
-
Blockade of the ubiquitin-conjugating enzyme CDC34 enhances anti myeloma activity of Bortezomib/Proteasome inhibitor PS-341
-
Chauhan D., Li G., Hideshima T., et al. Blockade of the ubiquitin-conjugating enzyme CDC34 enhances anti myeloma activity of Bortezomib/Proteasome inhibitor PS-341. Oncogene 23 (2004) 3597-3602
-
(2004)
Oncogene
, vol.23
, pp. 3597-3602
-
-
Chauhan, D.1
Li, G.2
Hideshima, T.3
-
58
-
-
0031890636
-
Role of MDM2 overexpression in doxorubicin resistance of breast carcinoma
-
Suzuki A., Toi M., Yamamoto Y., Saji S., Muta M., and Tominaga T. Role of MDM2 overexpression in doxorubicin resistance of breast carcinoma. Jpn J Cancer Res 89 (1998) 221-227
-
(1998)
Jpn J Cancer Res
, vol.89
, pp. 221-227
-
-
Suzuki, A.1
Toi, M.2
Yamamoto, Y.3
Saji, S.4
Muta, M.5
Tominaga, T.6
-
59
-
-
0343517136
-
Predictive value of p53, mdm-2, p21 and mib-1 for chemotherapy response in advanced breast cancer
-
Sjostrom J., Blomqvist C., Heikkila P., et al. Predictive value of p53, mdm-2, p21 and mib-1 for chemotherapy response in advanced breast cancer. Clin Cancer Res 6 (2000) 3103-3110
-
(2000)
Clin Cancer Res
, vol.6
, pp. 3103-3110
-
-
Sjostrom, J.1
Blomqvist, C.2
Heikkila, P.3
-
60
-
-
1342332342
-
Chemosensitization and radiosensitization of human cancer by antisense anti-MDM2 oligonucleotides: in vitro and in vivo activities and mechanisms
-
Wang H., Oliver P., Zhang Z., Agrawal S., and Zhang R. Chemosensitization and radiosensitization of human cancer by antisense anti-MDM2 oligonucleotides: in vitro and in vivo activities and mechanisms. Ann N Y Acad Sci 1002 (2003) 217-235
-
(2003)
Ann N Y Acad Sci
, vol.1002
, pp. 217-235
-
-
Wang, H.1
Oliver, P.2
Zhang, Z.3
Agrawal, S.4
Zhang, R.5
-
61
-
-
33746646758
-
Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukaemia
-
Kojima K., Konopleva M., McQueen T., O'Brien S., Plunkett W., and Andreeff M. Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukaemia. Blood 108 (2006) 993-1000
-
(2006)
Blood
, vol.108
, pp. 993-1000
-
-
Kojima, K.1
Konopleva, M.2
McQueen, T.3
O'Brien, S.4
Plunkett, W.5
Andreeff, M.6
-
62
-
-
28144451956
-
Downregulation of MDM2 expression by RNAi inhibits LoVo human colorectal adenocarcinoma cells growth and the treatment of LoVo cells with mdm2siRNA3 enhances sensitivity to cisplatin
-
Yu Y., Sun P., Sun L.C., et al. Downregulation of MDM2 expression by RNAi inhibits LoVo human colorectal adenocarcinoma cells growth and the treatment of LoVo cells with mdm2siRNA3 enhances sensitivity to cisplatin. Biochem Biophys Res Commun 339 (2006) 71-78
-
(2006)
Biochem Biophys Res Commun
, vol.339
, pp. 71-78
-
-
Yu, Y.1
Sun, P.2
Sun, L.C.3
-
63
-
-
1842421376
-
A dynamic role of HAUSP in the p53-Mdm2 pathway
-
Li M., Brooks C.L., Kon N., and Gu W. A dynamic role of HAUSP in the p53-Mdm2 pathway. Mol Cell 13 (2004) 879-886
-
(2004)
Mol Cell
, vol.13
, pp. 879-886
-
-
Li, M.1
Brooks, C.L.2
Kon, N.3
Gu, W.4
-
64
-
-
0024024371
-
Cycloheximide-resistant temperature-sensitive lethal mutations of Saccharomyces cerevisiae
-
McCusker J.H., and Haber J.E. Cycloheximide-resistant temperature-sensitive lethal mutations of Saccharomyces cerevisiae. Genetics 119 (1988) 305-315
-
(1988)
Genetics
, vol.119
, pp. 305-315
-
-
McCusker, J.H.1
Haber, J.E.2
-
65
-
-
1842405431
-
Yeast cycloheximide-resistant crl mutants are proteasome mutants defective in protein degradation
-
Gerlinger U.M., Guckel R., Hoffmann M., Wolf D.H., and Hilt W. Yeast cycloheximide-resistant crl mutants are proteasome mutants defective in protein degradation. Mol Biol Cell 8 (1997) 2487-2499
-
(1997)
Mol Biol Cell
, vol.8
, pp. 2487-2499
-
-
Gerlinger, U.M.1
Guckel, R.2
Hoffmann, M.3
Wolf, D.H.4
Hilt, W.5
-
66
-
-
0027379925
-
Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit
-
Gordon C., McGurk G., Dillon P., Rosen C., and Hastie N.D. Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit. Nature 366 (1993) 355-357
-
(1993)
Nature
, vol.366
, pp. 355-357
-
-
Gordon, C.1
McGurk, G.2
Dillon, P.3
Rosen, C.4
Hastie, N.D.5
-
67
-
-
14444278047
-
The pad1+ gene encodes a subunit of the 26S proteasome in fission yeast
-
Penney M., Wilkinson C., Wallace M., et al. The pad1+ gene encodes a subunit of the 26S proteasome in fission yeast. J Biol Chem 272 (1998) 23938-23945
-
(1998)
J Biol Chem
, vol.272
, pp. 23938-23945
-
-
Penney, M.1
Wilkinson, C.2
Wallace, M.3
-
68
-
-
0029186099
-
Subunits of the regulatory complex of the 26S protease
-
Dubiel W., Ferrell K., and Rechsteiner M. Subunits of the regulatory complex of the 26S protease. Mol Biol Rep 21 (1995) 27-34
-
(1995)
Mol Biol Rep
, vol.21
, pp. 27-34
-
-
Dubiel, W.1
Ferrell, K.2
Rechsteiner, M.3
-
69
-
-
0026764311
-
Proteolysis, proteasomes and antigen presentation
-
Goldberg A.L., and Rock K.L. Proteolysis, proteasomes and antigen presentation. Nature 357 (1992) 375-379
-
(1992)
Nature
, vol.357
, pp. 375-379
-
-
Goldberg, A.L.1
Rock, K.L.2
-
70
-
-
0035158568
-
Dominant effector genetics in mammalian cells
-
Xu X., Leo C., Jang Y., et al. Dominant effector genetics in mammalian cells. Nat Genet 27 (2001) 23-29
-
(2001)
Nat Genet
, vol.27
, pp. 23-29
-
-
Xu, X.1
Leo, C.2
Jang, Y.3
-
71
-
-
0032527991
-
Proteasome inhibition leads to the activation of all members of the heat shock factor family
-
Kawazoe Y., Nakai A., Tanabe M., and Nagata K. Proteasome inhibition leads to the activation of all members of the heat shock factor family. Eur J Biochem 255 (1998) 356-362
-
(1998)
Eur J Biochem
, vol.255
, pp. 356-362
-
-
Kawazoe, Y.1
Nakai, A.2
Tanabe, M.3
Nagata, K.4
-
72
-
-
0031149453
-
Involvement of heat shock factor in regulating transcriptional activation of MDR1 gene in multidrug resistant cells
-
Kim S.H., Hur W.Y., Kang C.D., Lim Y.S., Kim D.W., and Chung B.S. Involvement of heat shock factor in regulating transcriptional activation of MDR1 gene in multidrug resistant cells. Cancer Lett 115 (1997) 9-14
-
(1997)
Cancer Lett
, vol.115
, pp. 9-14
-
-
Kim, S.H.1
Hur, W.Y.2
Kang, C.D.3
Lim, Y.S.4
Kim, D.W.5
Chung, B.S.6
-
73
-
-
21244472965
-
Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis
-
Zhong Q., Gao W., Du F., and Wang X. Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis. Cell 121 (2005) 1085-1095
-
(2005)
Cell
, vol.121
, pp. 1085-1095
-
-
Zhong, Q.1
Gao, W.2
Du, F.3
Wang, X.4
-
74
-
-
22344436226
-
Constitutive proteasome-mediated turnover of Bfl-1/A1 and its processing in response to TNF receptor activation in FL512 pro-B cells convert it into a prodeath factor
-
Kucharczak J.F., Simmons M.J., Duckett C.S., and Gelinas C. Constitutive proteasome-mediated turnover of Bfl-1/A1 and its processing in response to TNF receptor activation in FL512 pro-B cells convert it into a prodeath factor. Cell Death Differ 12 (2005) 1225-1239
-
(2005)
Cell Death Differ
, vol.12
, pp. 1225-1239
-
-
Kucharczak, J.F.1
Simmons, M.J.2
Duckett, C.S.3
Gelinas, C.4
-
75
-
-
35448997622
-
-
Smith L, Welham KJ, Watson MB, Drew PJ, Lind MJ, Cawkwell L. The proteomic analysis of cisplatin resistance in breast cancer cells. Oncol Res, in press.
-
-
-
|