Enantioselective enzymatic desymmetrization of highly functionalized meso tetrahydropyranyl diols

Organic Letters

Volumn 11, Issue 21, 2009, Pages 4950-4953

  Candy, Mathieu ^a   Audran, Gérard ^a   Bienaymé, Hugues ^b   Bressy, Cyril ^a   Pons, Jean Marc ^a  

^a AIX MARSEILLE UNIVERSITÉ   (France)

^b TARGEON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 70350630566     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol902107g     Document Type: Article

References (80)

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75. See Supporting Information.
76. PPL: Pig Pancreatic Lipase; PFL: Pseudommtas fluorescens; RML: Rhizomucor miehei Lipase; CAL-B: Candida antarctica B Lipase; CRL: Candida rugosa Lipase type VII.
77. Vinyl acetate was used here as reagent and co-solvent to solubilize the meso diol during the desymmetrization reaction.
78. CCDC 739869 contains the supplementary crystallographic data for this paper. These data can be obtained free of charge from the Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data-request/cif.
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