-
1
-
-
0032577483
-
Regulation of the calmodulin-stimulated protein phosphatase, calcineurin
-
Klee CB, Ren H, Wang X. Regulation of the calmodulin-stimulated protein phosphatase, calcineurin. J Biol Chem 1998 273 : 13367 13370.
-
(1998)
J Biol Chem
, vol.273
, pp. 13367-13370
-
-
Klee, C.B.1
Ren, H.2
Wang, X.3
-
3
-
-
0026643141
-
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation
-
Clipstone NA, Crabtree GR. Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation. Nature 1992 357 : 695 697.
-
(1992)
Nature
, vol.357
, pp. 695-697
-
-
Clipstone, N.A.1
Crabtree, G.R.2
-
4
-
-
0037077135
-
Transcriptional mechanisms underlying lymphocyte tolerance
-
Macian F, Garcia-Cozar F, Im SH, Horton HF, Byrne MC, Rao A. Transcriptional mechanisms underlying lymphocyte tolerance. Cell 2002 109 : 719 731.
-
(2002)
Cell
, vol.109
, pp. 719-731
-
-
MacIan, F.1
Garcia-Cozar, F.2
Im, S.H.3
Horton, H.F.4
Byrne, M.C.5
Rao, A.6
-
5
-
-
0030973579
-
Transcription factors of the NFAT family: Regulation and function
-
Rao A, Luo C, Hogan PG. Transcription factors of the NFAT family: regulation and function. Annu Rev Immunol 1997 15 : 707 747.
-
(1997)
Annu Rev Immunol
, vol.15
, pp. 707-747
-
-
Rao, A.1
Luo, C.2
Hogan, P.G.3
-
6
-
-
33746228122
-
FOXP3 controls regulatory T cell function through cooperation with NFAT
-
Wu Y, Borde M, Heissmeyer V et al. FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell 2006 126 : 375 387.
-
(2006)
Cell
, vol.126
, pp. 375-387
-
-
Wu, Y.1
Borde, M.2
Heissmeyer, V.3
-
7
-
-
0024589097
-
Organ-specific autoimmune disease induced in mice by elimination of T cell subsets. V. Neonatal administration of cyclosporin A causes autoimmune disease
-
Sakaguchi S, Sakaguchi N. Organ-specific autoimmune disease induced in mice by elimination of T cell subsets. V. Neonatal administration of cyclosporin A causes autoimmune disease. J Immunol 1989 142 : 471 480.
-
(1989)
J Immunol
, vol.142
, pp. 471-480
-
-
Sakaguchi, S.1
Sakaguchi, N.2
-
8
-
-
33644844341
-
Molecular mechanisms underlying FOXP3 induction in human T cells
-
Mantel PY, Ouaked N, Ruckert B et al. Molecular mechanisms underlying FOXP3 induction in human T cells. J Immunol 2006 176 : 3593 3602.
-
(2006)
J Immunol
, vol.176
, pp. 3593-3602
-
-
Mantel, P.Y.1
Ouaked, N.2
Ruckert, B.3
-
10
-
-
0242584870
-
TGF-beta1 regulates lymphocyte homeostasis by preventing activation and subsequent apoptosis of peripheral lymphocytes
-
Bommireddy R, Saxena V, Ormsby I et al. TGF-beta1 regulates lymphocyte homeostasis by preventing activation and subsequent apoptosis of peripheral lymphocytes. J Immunol 2003 170 : 4612 4622.
-
(2003)
J Immunol
, vol.170
, pp. 4612-4622
-
-
Bommireddy, R.1
Saxena, V.2
Ormsby, I.3
-
12
-
-
0035920554
-
Requirement for transforming growth factor beta1 in controlling t cell apoptosis
-
Chen W, Jin W, Tian H et al. Requirement for transforming growth factor beta1 in controlling t cell apoptosis. J Exp Med 2001 194 : 439 453.
-
(2001)
J Exp Med
, vol.194
, pp. 439-453
-
-
Chen, W.1
Jin, W.2
Tian, H.3
-
13
-
-
13544274450
-
Distinct effects of TGF-beta 1 on CD4+ and CD8+ T cell survival, division, and IL-2 production: A role for T cell intrinsic Smad3
-
McKarns SC, Schwartz RH. Distinct effects of TGF-beta 1 on CD4+ and CD8+ T cell survival, division, and IL-2 production: a role for T cell intrinsic Smad3. J Immunol 2005 174 : 2071 2083.
-
(2005)
J Immunol
, vol.174
, pp. 2071-2083
-
-
McKarns, S.C.1
Schwartz, R.H.2
-
14
-
-
0037867066
-
Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation
-
Chen CH, Seguin-Devaux C, Burke NA et al. Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation. J Exp Med 2003 197 : 1689 1699.
-
(2003)
J Exp Med
, vol.197
, pp. 1689-1699
-
-
Chen, C.H.1
Seguin-Devaux, C.2
Burke, N.A.3
-
15
-
-
41549164685
-
TGFbeta1 deficiency does not affect the generation and maintenance of CD4(+)CD25(+)FOXP3(+) putative T(reg) cells, but causes their numerical inadequacy and loss of regulatory function
-
Bommireddy R, Babcock GF, Singh RR, Doetschman T. TGFbeta1 deficiency does not affect the generation and maintenance of CD4(+)CD25(+)FOXP3(+) putative T(reg) cells, but causes their numerical inadequacy and loss of regulatory function. Clin Immunol 2008 127 : 206 213.
-
(2008)
Clin Immunol
, vol.127
, pp. 206-213
-
-
Bommireddy, R.1
Babcock, G.F.2
Singh, R.R.3
Doetschman, T.4
-
16
-
-
0025893168
-
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
-
Liu J, Farmer JD, Lane WS, Friedman J, Weissman I, Schreiber SL. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 1991 66 : 807 815.
-
(1991)
Cell
, vol.66
, pp. 807-815
-
-
Liu, J.1
Farmer, J.D.2
Lane, W.S.3
Friedman, J.4
Weissman, I.5
Schreiber, S.L.6
-
17
-
-
0033565626
-
Transforming growth factor beta1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis
-
Engle SJ, Hoying JB, Boivin GP, Ormsby I, Gartside PS, Doetschman T. Transforming growth factor beta1 suppresses nonmetastatic colon cancer at an early stage of tumorigenesis. Cancer Res 1999 59 : 3379 3386.
-
(1999)
Cancer Res
, vol.59
, pp. 3379-3386
-
-
Engle, S.J.1
Hoying, J.B.2
Boivin, G.P.3
Ormsby, I.4
Gartside, P.S.5
Doetschman, T.6
-
18
-
-
33748849303
-
Self-antigen recognition by TGFbeta1-deficient T cells causes their activation and systemic inflammation
-
Bommireddy R, Pathak LJ, Martin J et al. Self-antigen recognition by TGFbeta1-deficient T cells causes their activation and systemic inflammation. Lab Invest 2006 86 : 1008 1019.
-
(2006)
Lab Invest
, vol.86
, pp. 1008-1019
-
-
Bommireddy, R.1
Pathak, L.J.2
Martin, J.3
-
19
-
-
19544382508
-
Elimination of both CD4(+) and CD8(+) T cells but not B cells eliminates inflammation and prolongs the survival of TGFbeta1-deficient mice
-
Bommireddy R, Engle SJ, Ormsby I, Boivin GP, Babcock GF, Doetschman T. Elimination of both CD4(+) and CD8(+) T cells but not B cells eliminates inflammation and prolongs the survival of TGFbeta1-deficient mice. Cell Immunol 2004 232 : 96 104.
-
(2004)
Cell Immunol
, vol.232
, pp. 96-104
-
-
Bommireddy, R.1
Engle, S.J.2
Ormsby, I.3
Boivin, G.P.4
Babcock, G.F.5
Doetschman, T.6
-
20
-
-
33745633856
-
Inhibition of CD4+CD25+ regulatory T cell function by calcineurin dependent interleukin-2 production
-
Zeiser RS, Nguyen VH, Beilhack A et al. Inhibition of CD4+CD25+ regulatory T cell function by calcineurin dependent interleukin-2 production. Blood 2006 108 : 390 399.
-
(2006)
Blood
, vol.108
, pp. 390-399
-
-
Zeiser, R.S.1
Nguyen, V.H.2
Beilhack, A.3
-
21
-
-
18644381923
-
Inhibitory and stimulatory effects of cyclosporine A on the development of regulatory T cells in vivo
-
Kawai M, Kitade H, Mathieu C, Waer M, Pirenne J. Inhibitory and stimulatory effects of cyclosporine A on the development of regulatory T cells in vivo. Transplantation 2005 79 : 1073 1077.
-
(2005)
Transplantation
, vol.79
, pp. 1073-1077
-
-
Kawai, M.1
Kitade, H.2
Mathieu, C.3
Waer, M.4
Pirenne, J.5
-
22
-
-
0034663755
-
Differential effects of cyclosporine A, methylprednisolone, mycophenolate, and rapamycin on CD154 induction and requirement for NFkappaB: Implications for tolerance induction
-
Smiley ST, Csizmadia V, Gao W, Turka LA, Hancock WW. Differential effects of cyclosporine A, methylprednisolone, mycophenolate, and rapamycin on CD154 induction and requirement for NFkappaB: implications for tolerance induction. Transplantation 2000 70 : 415 419.
-
(2000)
Transplantation
, vol.70
, pp. 415-419
-
-
Smiley, S.T.1
Csizmadia, V.2
Gao, W.3
Turka, L.A.4
Hancock, W.W.5
-
23
-
-
0034719361
-
Brief cyclosporine treatment prevents intrathymic (IT) tolerance induction and precipitates acute rejection in an IT rat cardiac allograft model
-
Smith CR, Mohanakumar T, Shimizu Y et al. Brief cyclosporine treatment prevents intrathymic (IT) tolerance induction and precipitates acute rejection in an IT rat cardiac allograft model. Transplantation 2000 69 : 294 299.
-
(2000)
Transplantation
, vol.69
, pp. 294-299
-
-
Smith, C.R.1
Mohanakumar, T.2
Shimizu, Y.3
-
24
-
-
0023794047
-
Abnormal differentiation of thymocytes in mice treated with cyclosporin A
-
Gao EK, Lo D, Cheney R, Kanagawa O, Sprent J. Abnormal differentiation of thymocytes in mice treated with cyclosporin A. Nature 1988 336 : 176 179.
-
(1988)
Nature
, vol.336
, pp. 176-179
-
-
Gao, E.K.1
Lo, D.2
Cheney, R.3
Kanagawa, O.4
Sprent, J.5
-
25
-
-
59849123078
-
Calcineurin negatively regulates TLR-mediated activation pathways
-
Kang YJ, Kusler B, Otsuka M et al. Calcineurin negatively regulates TLR-mediated activation pathways. J Immunol 2007 179 : 4598 4607.
-
(2007)
J Immunol
, vol.179
, pp. 4598-4607
-
-
Kang, Y.J.1
Kusler, B.2
Otsuka, M.3
-
26
-
-
0035873731
-
Genetic regulation of autoimmune disease: BALB/c background TGF-beta 1-deficient mice develop necroinflammatory IFN-gamma-dependent hepatitis
-
Gorham JD, Lin JT, Sung JL, Rudner LA, French MA. Genetic regulation of autoimmune disease: BALB/c background TGF-beta 1-deficient mice develop necroinflammatory IFN-gamma-dependent hepatitis. J Immunol 2001 166 : 6413 6422.
-
(2001)
J Immunol
, vol.166
, pp. 6413-6422
-
-
Gorham, J.D.1
Lin, J.T.2
Sung, J.L.3
Rudner, L.A.4
French, M.A.5
-
27
-
-
36048956108
-
TGFbeta1 and T(reg) cells: Alliance for tolerance
-
Bommireddy R, Doetschman T. TGFbeta1 and T(reg) cells: alliance for tolerance. Trends Mol Med 2007 13 : 492 501.
-
(2007)
Trends Mol Med
, vol.13
, pp. 492-501
-
-
Bommireddy, R.1
Doetschman, T.2
|