Native LDL upregulation of ATP-binding cassette transporter-1 in human vascular endothelial cells

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 22, Issue 1, 2002, Pages 127-132

  Liao, Hailing ^a   Langmann, Thomas ^a   Schmitz, Gerd ^a   Zhu, Yi ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

ABCA1; Cholesterol; Endothelial cells; LDL; Liver X receptor

Indexed keywords

ABC TRANSPORTER; CHOLESTEROL; LIVER X RECEPTOR; LOW DENSITY LIPOPROTEIN; LUCIFERASE; MESSENGER RNA; RECEPTOR PROTEIN; RETINOID X RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; DNA RESPONSIVE ELEMENT; ENZYME ACTIVITY; GENE ACTIVATION; GENE DELETION; GENE EXPRESSION REGULATION; GENE MAPPING; GENE MUTATION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; VASCULAR ENDOTHELIUM;

APOLIPOPROTEIN A-I; ATP-BINDING CASSETTE TRANSPORTERS; CELLS, CULTURED; CHOLESTEROL; CHOLESTEROL, LDL; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; LUCIFERASES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, RETINOIC ACID; RECEPTORS, THYROID HORMONE; RNA, MESSENGER; TRANSFECTION; UP-REGULATION;

EID: 0036144713     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/hq1201.101772     Document Type: Article

References (33)

1. Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency
2. The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease
3. Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
4. Tangier disease as a test of the reverse cholesterol transport hypothesis
5. Cholesterol efflux regulatory protein, Tangier disease and familial high-density lipoprotein deficiency
6. Intracellular cholesterol transport
7. Age and residual cholesterol efflux affect HDL cholesterol levels and coronary artery disease in ABCA1 heterozygotes
8. Tangier disease and ABCA1
9. Specific binding of apoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1
10. LDL induces transcription factor activator protein-1 in human endothelial cells
11. Native low density lipoprotein-induced calcium transients trigger VCAM-1 and E-selectin expression in cultured human vascular endothelial cells
12. Low-density lipoprotein activates Jun N-terminal kinase (JNK) in human endothelial cells
13. Low-density lipoprotein promotes caveolin-1 and ras translocation to caveolae: Role of cholesterol in endothelial signaling
14. Molecular cloning of the human ATP-binding cassette transporter 1 (hABCl): Evidence for sterol-dependent regulation in macrophages
15. The adenosine 5′,5‴,P1,P4-tetraphosphate receptor is at the cell surface of heart cells
16. Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor
17. Nuclear receptor that identifies a novel retinoic acid response pathway
18. The orphan nuclear receptor LXRα is positively and negatively regulated by distinct products of mevalonate metabolism
19. Transport of lipids from Golgi to plasma membrane is defective in Tangier disease patients and Abcl-deficient mice
20. Decreased reverse cholesterol transport from Tangier disease fibroblasts: Acceptor specificity and effect of brefeldin on lipid efflux
21. Effect of low-density lipoprotein on endothelial cell membrane fluidity and mono-nuclear cell attachment
22. Complete genomic sequence of the human ABCA1 gene: Analysis of the human and mouse ATP-binding cassette A promoter
23. ABC1 gene expression and apoA-I-mediated cholesterol efflux are regulated by LXR
24. The correlation of ATP-binding cassette 1 mRNA levels with cholesterol efflux from various cell lines
25. Localization of human ATP-binding cassette transporter 1 (abc1) in normal and atherosclerotic tissues
26. A two-step mechanism for free cholesterol and phospholipid efflux from human vascular cells to apolipoprotein A-1
27. Specific docking of apolipoprotein A-I at the cell surface requires a functional ABCA1 transporter
28. Involvement of caveolin-1 in cholesterol enrichment of high density lipoprotein during its assembly by apolipoprotein and THP-1 cells
29. Membrane lipid domains distinct from cholesterol/sphingomyelin-rich rafts are involved in the ABCA1-mediated lipid secretory pathway
30. Structure, function and regulation of the ABC1 gene product
31. 27-Hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells
32. Sterol 27-hydroxylase: High levels of activity in vascular endothelium
33. The zinc finger protein 202 (znf202) is a transcriptional repressor of ATP binding cassette transporter a1 (abca1) and abcg1 gene expression and a modulator of cellular lipid efflux