Synthetic peptide-based cancer vaccines: Lessons learned and hurdles to overcome

Current Molecular Medicine

Volumn 9, Issue 6, 2009, Pages 683-693

  Voskens, Caroline J ^a   Strome, Scott E ^a   Sewell, Duane A ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer; CTL; HLA class I; HLA class II; Immunotherapy; Synthetic peptide; T helper cell; Tumor antigen

Indexed keywords

CANCER VACCINE; CYCLOPHOSPHAMIDE; DENDRITIC CELL VACCINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPITOPE; GAMMA INTERFERON; GLYCOPROTEIN GP 100; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; KEYHOLE LIMPET HEMOCYANIN; LIPOPEPTIDE; MELAN A; MUCIN 1; NY ESO 1 ANTIGEN; PEPTIDE VACCINE; PROTEIN E6; PROTEIN E7; TETANUS TOXOID;

ANTIGEN EXPRESSION; BINDING AFFINITY; BREAST CANCER; CANCER IMMUNIZATION; CANCER PATIENT; CANCER STAGING; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CLINICAL TRIAL; CYTOTOXICITY; DRUG EFFICACY; ENZYME LINKED IMMUNOSORBENT ASSAY; HELPER CELL; HUMAN; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOGENICITY; IMMUNOLOGICAL TOLERANCE; IN VITRO STUDY; IN VIVO STUDY; LOW DRUG DOSE; LUNG NON SMALL CELL CANCER; LYMPHOCYTE ACTIVATION; MALIGNANT NEOPLASTIC DISEASE; MELANOMA; METASTASIS; NONHUMAN; OVARY CANCER; PANCREAS CANCER; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TUMOR IMMUNITY; TUMOR REGRESSION; UTERINE CERVIX CANCER; UVEA MELANOMA; VAGINA CANCER;

CANCER VACCINES; CD4-POSITIVE T-LYMPHOCYTES; CLINICAL TRIALS AS TOPIC; EPITOPES; HUMANS; IMMUNOTHERAPY; VACCINES, SUBUNIT; VACCINES, SYNTHETIC;

EID: 70350552366     PISSN: 15665240     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652409788970724     Document Type: Review

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