Facilitation of central imidazoline I 1-site/extracellular signal-regulated kinase/p38 mitogen-activated protein kinase signalling mediates the hypotensive effect of ethanol in rats with acute renal failure

British Journal of Pharmacology

Volumn 158, Issue 6, 2009, Pages 1629-1640

  El Mas, Mahmoud M ^a   El Gowelli, Hanan M ^a   Ghazal, Abdel Rheem M ^a   Harraz, Osama F ^a   Mohy El Din, Mahmoud M ^a  

^a Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

Acute renal failure; Blood pressure; Ethanol; Mitogen activated protein kinases; Sympatholytic drugs

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALCOHOL; EFAROXAN; GLYCEROL; GUANABENZ; HEXAMETHONIUM; IMIDAZOLINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MOXONIDINE; PRAZOSIN; YOHIMBINE;

ACUTE KIDNEY FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; DRUG EFFECT; HEART RATE; HYPOTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SYMPATHETIC TONE;

ANIMALS; BLOOD PRESSURE; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; GLYCEROL; HEART RATE; HYPOTENSION; IMIDAZOLINE RECEPTORS; KIDNEY FAILURE, ACUTE; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

EID: 70350543342     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00444.x     Document Type: Article

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