Berberine chloride causes a caspase-independent, apoptotic-like death in Leishmania donovani promastigotes

Free Radical Research

Volumn 43, Issue 11, 2009, Pages 1101-1110

  Saha, Piu ^a   Sen, Rupashree ^a   Hariharan, Chellaram ^b   Kumar, Deepak ^c   Das, Padma ^c   Chatterjee, Mitali ^a  

^a INSTITUTE OF POST GRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

^b Central Drugs Laboratory India   (India)

^c INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

Anti leishmanial; Apoptosis; Berberine chloride; Leishmaniasis; Oxidative stress; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; BERBERINE; CALCIUM; CALCIUM ION; CASPASE; FREE RADICAL; KETONE DERIVATIVE; PHOSPHATIDYLSERINE; REACTIVE OXYGEN METABOLITE; THIOL; UNCLASSIFIED DRUG; VALYL ALANYL ASPARAGINE (METHOXY)FLUOROMETHYLKETONE; ANTIPROTOZOAL AGENT; CASPASE INHIBITOR;

APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DEPOLARIZATION; DNA FRAGMENTATION; DRUG ACTIVITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IC 50; LEISHMANIA DONOVANI; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PROMASTIGOTE; ANIMAL; CYTOLOGY; DRUG EFFECTS; METABOLISM; MITOCHONDRION; OXIDATIVE STRESS; PARASITOLOGY; TUMOR CELL LINE; VISCERAL LEISHMANIASIS;

LEISHMANIA DONOVANI;

ANIMALS; ANTIPROTOZOAL AGENTS; APOPTOSIS; BERBERINE; CASPASE INHIBITORS; CASPASES; CELL LINE, TUMOR; DNA FRAGMENTATION; HUMANS; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 70350525419     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.1080/10715760903186124     Document Type: Article

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