메뉴 건너뛰기




Volumn 22, Issue 4, 2009, Pages 837-843

FoxO3a gene is a target of deletion in mouse lung adenocarcinoma

Author keywords

Carcinogenesis; FoxO3a; Lung adenocarcinoma; Tumor suppressor

Indexed keywords

TRANSCRIPTION FACTOR FKHRL1;

EID: 70350379161     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000507     Document Type: Article
Times cited : (13)

References (51)
  • 1
    • 33947593200 scopus 로고    scopus 로고
    • American Cancer Society:, American Cancer Society, Atlanta
    • American Cancer Society: Cancer Facts and Figures 2007. American Cancer Society, Atlanta, 2008.
    • (2008) Cancer Facts and Figures 2007
  • 4
    • 0037152658 scopus 로고    scopus 로고
    • Smoking molecular damage in bronchial epithelium
    • Wistuba II, Mao L and Gazdar AF: Smoking molecular damage in bronchial epithelium. Oncogene 21: 7298-7306, 2002.
    • (2002) Oncogene , vol.21 , pp. 7298-7306
    • Mao II, W.L.1    Gazdar, A.F.2
  • 5
    • 0036682309 scopus 로고    scopus 로고
    • Primary adenocarcinomas of the lung in nonsmokers show a distinct pattern of allelic imbalance
    • Wong MP, Lam WK, Wang E, Chiu SW, Lam CL and Chung LP: Primary adenocarcinomas of the lung in nonsmokers show a distinct pattern of allelic imbalance. Cancer Res 62: 4464-4468, 2002.
    • (2002) Cancer Res , vol.62 , pp. 4464-4468
    • Wong, M.P.1    Lam, W.K.2    Wang, E.3    Chiu, S.W.4    Lam, C.L.5    Chung, L.P.6
  • 10
    • 0037639968 scopus 로고    scopus 로고
    • Molecular genetics of lung cancer
    • Sekido Y, Fong KM and Minna JD: Molecular genetics of lung cancer. Ann Rev Med 54: 73-87, 2003.
    • (2003) Ann Rev Med , vol.54 , pp. 73-87
    • Sekido, Y.1    Fong, K.M.2    Minna, J.D.3
  • 14
    • 34648815009 scopus 로고    scopus 로고
    • Lung cancer in never smokers-a different disease
    • Sun S, Schiller JH and Gadzar AF: Lung cancer in never smokers-a different disease. Nat Rev Cancer 7: 778-790, 2007.
    • (2007) Nat Rev Cancer , vol.7 , pp. 778-790
    • Sun, S.1    Schiller, J.H.2    Gadzar, A.F.3
  • 15
    • 0031401656 scopus 로고    scopus 로고
    • Genetic alterations in mouse lung tumors: Implications for cancer prevention
    • Herzog CR, Lubet RA and You M: Genetic alterations in mouse lung tumors: implications for cancer prevention. J Cell Biochem 28/29: 49-63, 1997.
    • (1997) J Cell Biochem , vol.28-29 , pp. 49-63
    • Herzog, C.R.1    Lubet, R.A.2    You, M.3
  • 16
    • 0007142725 scopus 로고
    • Activation of the K-ras gene in spontaneously occurring and chemically-induced strain A mouse lung tumors
    • You M, Candrian U, Maronpot RR, Stoner GD and Anderson M: Activation of the K-ras gene in spontaneously occurring and chemically-induced strain A mouse lung tumors. Proc Natl Acad Sci USA 86: 3070-3074, 1989.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 3070-3074
    • You, M.1    Candrian, U.2    Maronpot, R.R.3    Stoner, G.D.4    Anderson, M.5
  • 19
    • 2442490689 scopus 로고    scopus 로고
    • Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: Implications for chromosome instability induction and tumor progression
    • Herzog CR, Bodon N, Pittman B, You M, Anderson MW, Maronpot RR, Massey TE and Devereux TR: Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: Implications for chromosome instability induction and tumor progression. Oncogene 23: 3033-3039, 2004.
    • (2004) Oncogene , vol.23 , pp. 3033-3039
    • Herzog, C.R.1    Bodon, N.2    Pittman, B.3    You, M.4    Anderson, M.W.5    Maronpot, R.R.6    Massey, T.E.7    Devereux, T.R.8
  • 20
    • 31744432744 scopus 로고    scopus 로고
    • Array CGH analysis reveals chromosomal aberrations in mouse lung adenocarcinomas induced by the human lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
    • Herzog CR, Desai D and Amin S: Array CGH analysis reveals chromosomal aberrations in mouse lung adenocarcinomas induced by the human lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Biochem Biophys Res Com 341: 856-863, 2006.
    • (2006) Biochem Biophys Res Com , vol.341 , pp. 856-863
    • Herzog, C.R.1    Desai, D.2    Amin, S.3
  • 21
    • 65249131768 scopus 로고    scopus 로고
    • Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene
    • You M, Wang D, Liu P, Vikis H, James M, Lu Y, Wang Y, Wang M, Chen Q, et al: Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene. Clin Cancer Res 15: 2666-2674, 2009.
    • (2009) Clin Cancer Res , vol.15 , pp. 2666-2674
    • You, M.1    Wang, D.2    Liu, P.3    Vikis, H.4    James, M.5    Lu, Y.6    Wang, Y.7    Wang, M.8    Chen, Q.9
  • 22
    • 0018096625 scopus 로고
    • Tobacco-specific nitrosamines: Formation from nicotine in vitro and during tobacco curing and carcinogenicity in strain A mice
    • Hecht SS, Chen CB, Hirota N, Ornaf RM, Tso TC and Hoffmann D: Tobacco-specific nitrosamines: formation from nicotine in vitro and during tobacco curing and carcinogenicity in strain A mice. J Natl Cancer Inst 60: 819-824, 1978.
    • (1978) J Natl Cancer Inst , vol.60 , pp. 819-824
    • Hecht, S.S.1    Chen, C.B.2    Hirota, N.3    Ornaf, R.M.4    Tso, T.C.5    Hoffmann, D.6
  • 23
    • 0018076222 scopus 로고
    • Vinyl carbamate as a promutagen and a more carcinogenic analog of ethyl carbamate
    • Dahl GA, Miller JA and Miller EC: Vinyl carbamate as a promutagen and a more carcinogenic analog of ethyl carbamate. Cancer Res 38: 3793-3804, 1978.
    • (1978) Cancer Res , vol.38 , pp. 3793-3804
    • Dahl, G.A.1    Miller, J.A.2    Miller, E.C.3
  • 24
    • 0034352861 scopus 로고    scopus 로고
    • Mechanisms of aflatoxin B1 lung tumorigenesis
    • Massey TE, Smith GB and Tam AS: Mechanisms of aflatoxin B1 lung tumorigenesis. Exp Lung Res 26: 673-683, 2000.
    • (2000) Exp Lung Res , vol.26 , pp. 673-683
    • Massey, T.E.1    Smith, G.B.2    Tam, A.S.3
  • 25
    • 0036169080 scopus 로고    scopus 로고
    • Specific chromosomal aberrations in mouse lung adenocarcinoma cell lines detected by spectral karyotyping: A comparison with human lung adenocarcinoma
    • Sargent LM, Senft JR, Lowry DT, Jefferson AM, Tyson FL, Malkinson AM, Coleman AE and Reynolds SH: Specific chromosomal aberrations in mouse lung adenocarcinoma cell lines detected by spectral karyotyping: a comparison with human lung adenocarcinoma. Cancer Res 62: 1152-1157, 2002.
    • (2002) Cancer Res , vol.62 , pp. 1152-1157
    • Sargent, L.M.1    Senft, J.R.2    Lowry, D.T.3    Jefferson, A.M.4    Tyson, F.L.5    Malkinson, A.M.6    Coleman, A.E.7    Reynolds, S.H.8
  • 28
    • 0035090391 scopus 로고    scopus 로고
    • Allelic deletion mapping on chromosome 6q and X chromosome inactivation clonality patterns in cervical intraepithelial neoplasia and invasive carcinoma
    • Chuaqui R, Silva M and Emmert-Buck M: Allelic deletion mapping on chromosome 6q and X chromosome inactivation clonality patterns in cervical intraepithelial neoplasia and invasive carcinoma. Gynecol Oncol 80: 364-371, 2001.
    • (2001) Gynecol Oncol , vol.80 , pp. 364-371
    • Chuaqui, R.1    Silva, M.2    Emmert-Buck, M.3
  • 29
    • 0032542364 scopus 로고    scopus 로고
    • Genetic instabilities in human cancers
    • Lengauer C, Kinzler KW and Vogelstein B: Genetic instabilities in human cancers. Nature 396: 643-649, 1998.
    • (1998) Nature , vol.396 , pp. 643-649
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 30
    • 0031972522 scopus 로고    scopus 로고
    • Cancer cells exhibit a mutator phenotype
    • Loeb LA: Cancer cells exhibit a mutator phenotype. Adv Cancer Res 72: 25-56, 1998.
    • (1998) Adv Cancer Res , vol.72 , pp. 25-56
    • Loeb, L.A.1
  • 31
    • 0037288474 scopus 로고    scopus 로고
    • Chromosome instability in cancer: How, when, and why?
    • Gisselsson D: Chromosome instability in cancer: how, when, and why? Adv Cancer Res 87: 1-29, 2003.
    • (2003) Adv Cancer Res , vol.87 , pp. 1-29
    • Gisselsson, D.1
  • 32
    • 0037126393 scopus 로고    scopus 로고
    • Cloning and characterization of the common fragile site FRA6F harboring a replicative senescence gene and frequently deleted in human tumors
    • Morelli C, Karayianni E, Magnanini C, Mungall AJ, Thorland E, Negrini M, Smith DI and Barbanti-Brodano G: Cloning and characterization of the common fragile site FRA6F harboring a replicative senescence gene and frequently deleted in human tumors. Oncogene 21: 7266-7276, 2002.
    • (2002) Oncogene , vol.21 , pp. 7266-7276
    • Morelli, C.1    Karayianni, E.2    Magnanini, C.3    Mungall, A.J.4    Thorland, E.5    Negrini, M.6    Smith, D.I.7    Barbanti-Brodano, G.8
  • 34
  • 37
    • 27844497945 scopus 로고    scopus 로고
    • FOXO transcription factors at the interface between longevity and tumor suppression
    • Greer EL and Brunet A: FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene 24: 7410-7425, 2005.
    • (2005) Oncogene , vol.24 , pp. 7410-7425
    • Greer, E.L.1    Brunet, A.2
  • 38
    • 49849093007 scopus 로고    scopus 로고
    • Unravelling the tumor-suppressive functions of FOXO proteins
    • Dansen TB and Burgering BM: Unravelling the tumor-suppressive functions of FOXO proteins. Trends Cell Biol 18: 421-429, 2008.
    • (2008) Trends Cell Biol , vol.18 , pp. 421-429
    • Dansen, T.B.1    Burgering, B.M.2
  • 39
    • 0037178789 scopus 로고    scopus 로고
    • FOXO forkhead transcription factors induce G(2)-M checkpoint in response to oxidative stress
    • Furukawa-Hibi Y, Yoshida-Araki K, Ohta T, Ikeda K and Motoyama N: FOXO forkhead transcription factors induce G(2)-M checkpoint in response to oxidative stress. J Biol Chem 277: 26729-26732, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 26729-26732
    • Furukawa-Hibi, Y.1    Yoshida-Araki, K.2    Ohta, T.3    Ikeda, K.4    Motoyama, N.5
  • 41
    • 0037134040 scopus 로고    scopus 로고
    • Tran H, Brunet A, Grenier JM, Datta SR, Fornace AJ Jr, DiStefano PS, Chiang LW and Greenberg ME: DNA repair pathway stimulated by the forkhead transcription factor FoxO3a through the Gadd45 protein. Science 296: 530-534, 2002.
    • Tran H, Brunet A, Grenier JM, Datta SR, Fornace AJ Jr, DiStefano PS, Chiang LW and Greenberg ME: DNA repair pathway stimulated by the forkhead transcription factor FoxO3a through the Gadd45 protein. Science 296: 530-534, 2002.
  • 42
    • 37349025432 scopus 로고    scopus 로고
    • FoxO3a is activated in response to hypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2
    • Bakker WJ, Harris IS and Mak TW: FoxO3a is activated in response to hypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2. Mol Cell 28: 941-953, 2007.
    • (2007) Mol Cell , vol.28 , pp. 941-953
    • Bakker, W.J.1    Harris, I.S.2    Mak, T.W.3
  • 43
    • 70350388451 scopus 로고    scopus 로고
    • FOXO3a stimulates a pro-apoptotic transcriptional program in response to human lung carcinogen nicotine-derived nitro-saminoketone
    • In press
    • Blake Jr DC, Mikse OR, Freeman WM and Herzog CR: FOXO3a stimulates a pro-apoptotic transcriptional program in response to human lung carcinogen nicotine-derived nitro-saminoketone. Lung Cancer (In press).
    • Lung Cancer
    • Blake Jr, D.C.1    Mikse, O.R.2    Freeman, W.M.3    Herzog, C.R.4
  • 45
    • 0034462121 scopus 로고    scopus 로고
    • Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN
    • Nakamura N, Ramaswany F, Vasquez S, Signoretti M, Loda M and Sellers WR: Forkhead transcription factors are critical effectors of cell death and cell cycle arrest downstream of PTEN. Mol Cell Biol 20: 8969-8982, 2000.
    • (2000) Mol Cell Biol , vol.20 , pp. 8969-8982
    • Nakamura, N.1    Ramaswany, F.2    Vasquez, S.3    Signoretti, M.4    Loda, M.5    Sellers, W.R.6
  • 47
    • 27844445642 scopus 로고    scopus 로고
    • Perturbations of the AKT signaling pathway in human cancer
    • Altomare DA and Testa JR: Perturbations of the AKT signaling pathway in human cancer. Oncogene 24: 7455-7464, 2005.
    • (2005) Oncogene , vol.24 , pp. 7455-7464
    • Altomare, D.A.1    Testa, J.R.2
  • 48
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering BM and Coffer PJ: Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376: 599-602, 1995.
    • (1995) Nature , vol.376 , pp. 599-602
    • Burgering, B.M.1    Coffer, P.J.2
  • 49
    • 49649127657 scopus 로고    scopus 로고
    • Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer
    • Engelman JA and Jänne PA: Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer. Clin Cancer Res 14: 2895-2899, 2008.
    • (2008) Clin Cancer Res , vol.14 , pp. 2895-2899
    • Engelman, J.A.1    Jänne, P.A.2
  • 51
    • 0142227019 scopus 로고    scopus 로고
    • Targeting the PI3K-Akt pathway in human cancer: Rationale and promise
    • Luo J, Manning BD and Cantley LC: Targeting the PI3K-Akt pathway in human cancer: rationale and promise. Cancer Cell 4: 257-262, 2003.
    • (2003) Cancer Cell , vol.4 , pp. 257-262
    • Luo, J.1    Manning, B.D.2    Cantley, L.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.