Array CGH analysis reveals chromosomal aberrations in mouse lung adenocarcinomas induced by the human lung carcinogen 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanone

Biochemical and Biophysical Research Communications

Volumn 341, Issue 3, 2006, Pages 856-863

  Herzog, Christopher R ^a   Desai, Dhimant ^a   Amin, Shantu ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

4 (Methylnitrosamino) 1 (3 pyridyl) 1 butanone; Array CGH; Chromosome instability; Lung adenocarcinoma

Indexed keywords

4 (METHYLNITROSAMINO) 1 (3 PYRIDYL) 1 BUTANONE; TOBACCO SMOKE;

ANIMAL TISSUE; ARTICLE; CHROMOSOMAL INSTABILITY; CHROMOSOME ABERRATION; COMPARATIVE GENOMIC HYBRIDIZATION; KARYOTYPE; LUNG ADENOCARCINOMA; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ADENOCARCINOMA; ANIMALS; CARCINOGENS; CELL LINE, TUMOR; CHROMOSOME ABERRATIONS; DNA; GENE DOSAGE; HUMANS; KARYOTYPING; LUNG NEOPLASMS; MICE; NITROSAMINES; NUCLEIC ACID HYBRIDIZATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS;

ANIMALIA; BACTERIA (MICROORGANISMS); NICOTIANA TABACUM;

EID: 31744432744     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.01.043     Document Type: Article

References (35)

1. T. Pejovic, S. Heims, C. Orndal, Y.S. Jin, N. Mandahl, H. Willen, and F. Mitelman Simple numerical chromosome aberrations in well-differentiated malignant epithelial tumors Cancer Genet. Cytogenet. 49 1990 95 101
2. L.A. Loeb Cancer cells exhibit a mutator phenotype Adv. Cancer Res. 72 1998 25 56
3. J. Breivik, and G. Gaudernack Genomic instability, DNA methylation, and natural selection in colorectal carcinogenesis Semin. Cancer Biol. 9 1999 245 254
4. C. Lengauer, K.W. Kinzler, and B. Vogelstein Genetic instabilities in human cancers Nature 396 1998 643 649
5. L.S. Michel, V. Liberal, A. Chatterjee, R. Kirchwegger, B. Pasche, W. Gerald, M. Dobles, P.K. Sorger, V.V.V.S. Murty, and R. Benezra MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells Nature 409 2001 355 359
6. J.C. Shen, and L.A. Loeb The Werner syndrome gene: the molecular basis of RecQ helicase-deficiency diseases Trends Genet. 16 2000 213 220
7. M. Dobles, V. Liberal, M.L. Scott, R. Benezra, and P.K. Sorger Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mas2 Cell 101 2000 635 645
8. K.K. Khanna, and S.P. Jackson DNA double strand-breaks: signaling, repair and the cancer connection Nature Genet. 27 2001 247 254
9. A. Dipple DNA adducts of chemical carcinogens Carcinogenesis (Lond.) 16 1995 437 441
10. S.S. Hecht DNA adduct formation from tobacco-specific N-nitrosamines Mutat. Res. 424 1999 127 142
11. M. You, U. Candrian, R.R. Maronpot, G.D. Stoner, and M. Anderson Activation of the K-ras gene in spontaneously occurring and chemically-induced strain A mouse lung tumors Proc. Natl. Acad. Sci. USA 86 1989 3070 3074
12. G.P. Pfeifer, and G.P. Holmquist Mutagenesis in the p53 gene Biochim. Biophys. Acta 1333 1997 M1 M8
13. C.R. Herzog, T.R. Devereux, B. Pittman, and M. You Carcinogenic-induction directs the selection of allelic losses in mouse lung tumorigenesis Cancer Res. 62 2002 6424 6429
14. C.R. Herzog, N. Bodon, B. Pittman, M. You, M.W. Anderson, R.R. Maronpot, T.E. Massey, and T.R. Devereux Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: implications for chromosome instability induction and tumor progression Oncogene 23 2004 3033 3039
15. M.P. Wong, W.K. Lam, E. Wang, S.W. Chiu, C.L. Lam, and L.P. Chung Primary adenocarcinomas of the lung in nonsmokers show a distinct pattern of allelic imbalance Cancer Res. 62 2002 4464 4468
16. S.M.H. Sy, N. Wong, T.S.K. Mok, M.-S. Tsao, T.-W. Lee, G. Tse, F.H. Blackhall, P.J. Johnson, and A.P. Yim Genetic alterations of lung adenocarcinoma in relation to smoking and ethnicity Lung Cancer 41 2003 91 99
17. M.P. Wong, L.-F. Fung, E. Wang, W.-S. Chow, S.-W. Chiu, W.-K. Lam, K.-K. Ho, E.S.K. Ma, T.S.K. Wan, and L.-P. Chung Chromosomal aberrations of primary lung adenocarcinomas in nonsmokers Cancer 97 2003 1263 1270
18. J.K. Cowell, S. Matsui, Y.D. Wang, J. LaDuca, J. Conroy, D. McQuaid, and N.J. Nowak Application of bacterial artificial chromosome array-based comparative genomic hybridization and spectral karyotyping to the analysis of glioblastoma multiforme Cancer Genet.Cytogenet. 151 2004 36 51
19. C.H. Herzog, Y. Wang, and M. You Allelic loss on distal chromosome 4 in mouse lung tumors localize a putative tumor suppressor gene to a region homologous with human chromosome 1p36 Oncogene 11 1995 1811 1815
20. A.S. Tam, T.R. Devereux, A.C. Patel, J.F. Foley, R.R. Maronpot, and T.E. Massey Perturbations of the Ink4a/Arf gene locus in aflatoxin B1-induced mouse lung tumors Carcinogenesis 24 2003 121 132
21. N.M. Thomson, P.M. Kenney, and L.A. Peterson The pyridyloxobutyl DNA adduct, O6- [4-oxo-4-(pyridyl)butyl]guanine, is detected in tissues from 4-(methylnitosamino)-1-(3-pyridyl)-1-butanone treated A/J mice Chem. Res. Toxicol. 16 2003 1 6
22. M. Wang, G. Cheng, S.J. Sturla, Y. Shi, E.J. McIntee, P.W. Villalta, P. Upadhyaya, and S.S. Hecht Identification of adducts formed by pyridyloxobutylation of deoxyguanosine and DNA by 4-(acetoxymethylnitrosamino)- 1-(3-pyridyl)-1-butanone, a chemically activated form of tobacco specific carcinogens Chem. Res. Toxicol. 16 2003 616 626
23. A. Bardelli, D.P. Cahill, G. Lederer, M.R. Speicher, K.W. Kinzler, B. Vogelstein, and C. Lengauer Carcinogen-specific induction of genetic instability Proc. Natl. Acad. Sci. USA 98 2001 5770 5775
24. J.B. Little Radiation carcinogenesis Carcinogenesis 21 2000 397 404
25. N.L. Komarova, and D. Wodarz Evolutionary dynamics of mutator phenotypes in cancer: implications for chemotherapy Cancer Res. 15 2003 6635 6642
26. F. Michor, I. Yoh, and M.A. Nowak Dynamics of cancer progression Nat. Rev. Cancer 4 2004 197 205
27. A.J. Levine p53 the cellular gatekeeper for growth and division Cell 88 1997 323 331
28. M.L Smith, and A.J. Fornace Jr. Genomic instability and the role of p53 mutations in cancer cells Curr. Opin. Oncol. 7 1995 69 75
29. M.B. Kastan, O. Onyekwere, D. Sidransky, B. Vogelstein, and R.W. Craig Participation of p53 protein in the cellular response to DNA damage Cancer Res. 51 1991 6304 6311
30. L. Zheng, A. Flesken-Nikitin, P.L. Chen, and W.H. Lee Deficiency of retinoblastoma gene in mouse embryonic stem cells leads to genetic instability Cancer Res. 62 2002 2498 2502
31. M. Sanchez-Cespedes, S.A. Ahrendt, S. Piantadosi, R. Rosell, M. Monzo, L. Wu, W.H. Westra, S.C. Yang, J. Jen, and D. Sidransky Chromosomal alterations in lung adenocarcinoma from smokers and nonsmokers Cancer Res. 61 2001 1309 1313
32. A.L. Tai, W.S. Yan, Y. Fang, D. Xie, J.S. Sham, and X.Y. Guan Recurrent chromosomal imbalances in non-small cell lung carcinoma: the association between 1q amplification and tumor recurrence Cancer 100 2004 1918 1927
33. J. Pei, B.R. Balsara, W. Li, S. Litwin, E. Gabrielson, M. Feder, J. Jen, and J.R. Testa Genomic imbalances in human lung adenocarcinomas and squamous cell carcinomas Genes Chromosomes Cancer 31 2001 282 287
34. O.M. Sieber, K. Heinimann, and I.P.M. Tomlinson Genomic instability-the engine of tumorigenesis? Nat. Rev. Cancer 3 2003 701 708
35. A. Jemel, R.C. Tiwara, T. Murray, A. Ghafoor, A. Samuels, E. Ward, E.J. Feuer, and M. Thun Cancer statistics, 2004 CA Cancer J. Clin. 54 2004 8 29