Allelotyping demonstrates common and distinct patterns of chromosomal loss in human lung cancer types

Genes Chromosomes and Cancer

Volumn 21, Issue 4, 1998, Pages 308-319

  Virmani, Arvind K ^a,b   Fong, Kwun M ^a   Kodagoda, Dulmini ^a   McIntire, Donald ^a   Hung, Jaclyn ^a   Tonk, Vijay ^c   Minna, John D ^a,b   Gazdar, Adi F ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ALLELE; ARTICLE; CANCER CELL CULTURE; CHROMOSOME 10Q; CHROMOSOME 11P; CHROMOSOME 13Q; CHROMOSOME 19P; CHROMOSOME 3P; CHROMOSOME 5Q; CHROMOSOME 6Q; CHROMOSOME 9P; CHROMOSOME DELETION; CONTROLLED STUDY; GENE DELETION; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; LUNG SMALL CELL CANCER; LYMPHOBLASTOID CELL; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

ADULT; AGED; AGED, 80 AND OVER; ALLELES; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, 1-3; CHROMOSOMES, HUMAN, 13-15; CHROMOSOMES, HUMAN, 19-20; CHROMOSOMES, HUMAN, 21-22 AND Y; CHROMOSOMES, HUMAN, 4-5; CHROMOSOMES, HUMAN, 6-12 AND X; FEMALE; GENOTYPE; HUMANS; LOSS OF HETEROZYGOSITY; LUNG NEOPLASMS; MALE; MIDDLE AGED; TUMOR CELLS, CULTURED;

EID: 0031971078     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(199804)21:4<308::AID-GCC4>3.0.CO;2-2     Document Type: Article

References (68)

1. Ah-See KW, Cooke TG, Pickford IR, Soutar D, Balmain A (1994) An allelotype of squamous carcinoma of the head and neck using microsatellitc markers. Cancer Res 54:1617-1621.
2. Aldaz CM, Chen T, Sahin A, Cunningham J, Bondy M (1995) Comparative allelotype of in situ and invasive human breast cancer: high frequency of microsatellitc instability in lobular breast carcinomas. Cancer Res 55:3976-3981.
3. Amfo K, Neyns B, Teugels E, Lissens W, Bourgain C, De Sutter P, Vandamme B, Vamos E, De Greve J (1995) Frequent deletion of chromosome 19 and a rare rearrangement of 19p 13.3 involving the insulin receptor gene in human ovarian cancer. Oncogene 11:351-358.
4. Aoki T, Mori T, Du X, Nisihira T, Matsubara T, Nakamura V (1994) Allelotype study of esophageal carcinoma. Genes Chromosomes Cancer 10:177-102.
5. Beckman JS, Weber JL (1992) Survey of human and rat microsatellites. Genornics 12:627-631.
6. Bepler G, Koehler A (1995) Multiple chromosomal aberrations and 11p allelotyping in lung cancer cell lines, Cancer Genet Cytogenet 84:39-45.
7. Cairns P, Polascik TJ, Eby Y, Tokino K, Califano J, Merlo A, Mao L, Herath J, Jenkins R, Westra W, Rutter JL, Buckler A, Gabrielson E, Tockman M, Cho KR, Hedrick L, Bova GS, Isaacs W, Koch W, Schwab D, Sidransky D (1995) Frequency of homozygous deletion at p16/CDKN2 in primary human tumours. Nature Genet 11:210-212.
8. Caron H, Peter M, van Sluis P, Speleman F, de Kraker J, Laureys G, Michon J, Brugieres L, Voute PA, Westerveld A, Slater R, Delattre O, Versteeg R (1995) Evidence for two tumour suppressor loci on chromosomal bands 1p35-36 involved in neuroblastoma: One probably imprinted, another associated with N-myc amplification. Hum Mol Genet 4:535-559.
9. Carrington M, Dean M (1994) A polymorphic dinucleotide repeat in the third intron of TAP1. Hum Mol Genet 3:218.
10. Cawkwell L, Lewis FA, Quirke P (1994) Frequency of allele loss of DCC, p53, RDI, WT1, NF1, NM23 and APC/MCC in colorectal cancer assayed by fluorescent multiplex polymerase chain reaction. Br J Cancer 70:813-818.
11. Chang WY, Cairns P, Schoenberg MP, Polascik TJ, Sidransky D (1995) Novel suppressor loci on chromosome 14q in primary bladder cancer. Cancer Res 55:3246-3249.
12. Chen H, Dmitry G, Robert T, Khaled R, Girgis, Nadaf S, David PC (1996) A functionally defective allele of TAP1 results in loss of MHC class1 antigen presentation in a human lung cancer. Nature Genet 13:210-213.
13. Chenu PC, Gosewehr JA, Kim TM, Velicescu M, Wan M, Zheng J, Felix JC, Cofer KF, Luo P, Biela BH, Godorov G, Dubeau L (1996) Potential role of the inactivated X chromosome in ovarian epithelial tumor development [see comments]. J Natl Cancer Inst 88:510-518.
14. Chiba I, Tukahashi T, Nau MM, D'Amico D, (Muriel DT, Mitsudomi T, Buchhagen DL, Carbone D, Piantadosi S, Koga H, Reissman P, Slamon D, Holmes EC, Minna J (1990) Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancer: Lung Cancer Study Group. Oncogene 5:1603-1610.
15. D'Amico D, Carbone DP, Johnson BE, Meltzer SJ, Minna JD (1992) Polymorphic sites within the MCC and APC loci reveal very frequent loss of heterozygosity in human small cell lung cancer. Cancer Res 52:1996-1999.
16. Deng G, Lu Y, Ziotnikov G, Thor AD, Smith HS (1996) Loss of heterozygosity in normal tissue adjacent to breast carcinoma. Science 274:2057-2061.
17. Don RH, Cox PT, Wainwright BJ, Baker K, Mattick JS (1991) "Touchdown" PCR to circumvent spurious priming during gene amplification. Nucleic Acids Res 19:4008.
18. Doyle A, Martin WJ, Funa K, Gazdar A, Carney D, Martin SE, Linnoila I, Cuttitta F, Mulshine J, Bunn P, Minna J (1985) Markedly decreased expression of class 1 histocompatibility antigens, protein, and mRNA in human small-cell lung cancer. J Exp Med 161:1135-1151.
19. Eppert K, Scherer SW, Ozcelik H, Pirone R, Hoodless P, Kim H, Tsui LC, Bapat B, Gallinger S, Andrulis IL, Thomsen GH, Wrana JL, Attisano L (1996) MADR2 maps to 18q21 and encodes a TGFbetaregulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell 86:543-552.
20. Fong KM, Biesterveld EJ, Virmani AK, Wistuba I, Sekido Y, Bader SA, Ahmadian M, Ong ST, Rassool FV, Zimmerman PV, Giaccone G, Gazdar AF, Minna JD (1997) FHIT and FRA3B 3p14.2 allele loss are common in lung cancer and preneoplastic bronchial lesions and are associated with cancer-related FHIT cDNA splicing abberrations. Cancer Res 57:2256-2267.
21. Fujino T, Risinger JI, Collins NK, Liu FS, Nishii H, Takahashi H, Westphal EM, Barrett JC, Sasaki H, Kohler MF, Berchuck A, Boyd J (1994) Allelotype of endometrial carcinoma. Cancer Res 54:4294-4298.
22. Hahn SA, Schutte M, Hoque AT, Moskaluk CA, da Costa LT, Rozenblum E, Weinstein CL, Fischer A, Yeo CJ, Hruban RH, Kern SE (1996) DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271:350-353.
23. Hamann U, Herbold C, Costa S, Solomayer E-F, Kaufmann M, Basten G, Ulrich H, Frenzel H, Komitowski D (1996) Allelic imbalance on chromosome 13q: Evidence for the involvement of BRCA2 and RB1 in sporadic breast cancer. Cancer Res 56:1988-1900.
24. Huang TH, Yeh PL, Martin MB, Straub RE, Gilliam TC, Caldwell CW, Skibba JL (1995) Genetic alterations of microsatellites on chromosome 18 in human breast carcinoma. Diag Molec Pathol 4:66-72.
25. Iizuka M, Sugiyama Y, Shiraishi M, Jones C, Sekiya T (1995) Allelic losses in human chromosome 11 in lung cancers. Genes Chromosomes Cancer 13:40-46.
26. Jones MH, Nakamura Y (1992) Detection of loss of heterozygosity at the human TP53 locus using a dinucleotide repeat polymorphism. Genes Chromosomes Cancer 5:89-90.
27. Knowles MA, Shaw ME, Proctor AJ (1993) Deletion mapping of chromosome 8 in cancers of the urinary bladder using restriction fragment length polymorphisms and microsatellite polymorphisms. Oncogene 8:1357-1364.
28. Knudson AG (1996) Hereditary cancer: Two hits revisited. J Cancer Res Clin Oncol 122:135-1401
29. Kohno T, Morishita K, Takano H, Shapiro DN, Yokota J (1994) Homozygous deletion at chromosome 2q33 in human small-cell lung carcinoma identified by arbitrarily primed PCR genomic fingerprinting. Oncogene 9:103-108.
30. Latif F, Tory K, Modi S, Graziano S, Gamble G, Douglas J, Heppell-Parton A, Rabbitts P, Zbar B, Lerman M (1993) Molecular characterisation of a large homozygous deletion in the small cell lung cancer cell line U2020: a strategy for cloning the putative tumor suppressor gene. Genes Chromomes Cancer 5:119-127.
31. Levin NA, Brzoska P, Gupta N, Minna JD, Gray JW, Christman MF (1994) Identification of frequent novel genetic alterations in small cell lung carcinoma. Cancer Res 54:5086-5091.
32. Levin NA, Brzoska PM, Warnock ML, Gray JW, Christman MF (1995) Identification of novel regions of altered DNA copy number in small cell lung tumors. Genes Chromosomes Cancer 13:175-185.
33. Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, Puc J, Miliaresis C, Rodgers L, McCombie R, Bigner SH, Giovanella BC, Ittmann M, Tycko B, Hibshoosh H, Wigler MH, Parsons R (1997) Pten, a putative protein tyrosine phosphatuse gene mutated in human brain, breast, and prostate cancer. Science 275:1943-1947.
34. Litt M, Luty JA (1989) A hypervariable microsatellite revealed by in vitro amplification of a dinucleotide repeat within the cardiac muscle actin gene. Am J Hum Genet 44:397-401.
35. Lu YJ, Dong XY, Guo SP, Zhang RG, Ke Y, Zhang LZ, Xu LH, Cheng SJ (1996) 2q-, a non-random chromosomal abnormality in human non-small-cell lung cancer. Carcinogenesis 17:1589-1593.
36. Lukeis R, Irving L, Garson M, Hasthorpe S (1990) Cytogenetics of non-small cell lung cancer: Analysis of consistent non-random abnormalities. Genes Chromosomes Cancer 2:116-124.
37. Mao L, Lee DJ, Tockman MS, Erozan YS, Askin F, Sidransky D (1994) Microsatellite alterations as clonal markers for the detection of human cancer. Proc Natl Acad Sci USA 91:9871-9875.
38. Merlo A, Gabrielson E, Mabry M, Vollmer R, Baylin SB, Sidransky D (1994) Homozygous deletion on chromosome 9p and loss of heterozygosity on 9q, 6p, and 6q in primary human small cell lung cancer. Cancer Res 54:2322-2326.
39. Minna JD (1992) In Braunwald E., Isselbacher K, Petersdorf R, Wilson J, Martin J, Fauci A (eds): Harrison's Principles of Internal Medicine. New York: McGraw-Hill, pp 1221-1229.
40. Mitelman F, Mertens F, Johansson B (1997) A breakpoint map of recurrent chromosomal rearrangements in human neoplasia. Nature Genet 15:417-474.
41. Munn KE, Walker RA, Varley JM (1995) Frequent alterations of chromosome 1 in ductal carcinoma in situ of the breast. Oncogene 10:1653-1657.
42. Neville EM, Stewart M, Myskow M, Donnelly RJ, Field JK (1995) Loss of heterozygosity at 9p23 defines a novel locus in non-small cell lung cancer. Oncogene 11:581-585.
43. Oie HK, Russell EK, Carney DN, Gazdar AF (1996) Cell culture methods for the establishment of the NCI series of lung cancer cell lines. J Cell Biochem 24:24-31.
44. Otterson GA, Kratzke RA, Coxon A, Kim YW, Kaye FJ (1994) Absence of p16INK4 protein is restricted to the subset of lung cancer lines that retains wildtype RB. Oncogene 9:3375-3378.
45. Rabbins P, Bergh J, Douglas J, Collins F, Waters J (1990) A submicroscopic homozygous deletion at the D3S3 locus in a cell line isolated from a small cell lung carcinoma. Genes Chromosomes Cancer 2:231-238.
46. Rasio D, Negrini M, Manenti G, Dragani TA, Croce CM (1995) Loss of heterozygosity at chromosome 11q in lung adenocarcinoma: Identification of three independent regions. Cancer Res 55:3988-3991.
47. Ritland SR, Ganju V, Jenkins RB (1995) Region-specific loss of heterozygosity on chromosome 19 is related to the morphologic type of human glioma. Genes Chromosomes Cancer 12:277-282.
48. Sato S, Nakamura Y, Tsuchiya E (1994) Difference of allelotype between squamous cell carcinoma and adenocarcinoma of the lung. Cancer Res 54:5652-5655.
49. Savitsky K, Sfez S, Tagle DA, Ziv Y, Sartiel A, Collins FS, Shiloh Y, Rotman G (1995) The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species. Human Mol Genet 4:2025-2032.
50. Shiseki M, Kohno T, Nishikawa R, Sameshima Y, Mizoguchi H, Yokota J (1994) Frequent allelic losses on chromosomes 2q, 18q, and 22q in advanced non-small cell lung carcinoma. Cancer Res 54:5643-5648.
51. Smith JR, Freije D, Carpten JD, Gronberg H, Xu JF, Isaacs SD, Brownstein MJ, Bova GS, Guo H, Bujnovszky P, Nusskern DR, Dumber JE, Bergh A, Emanuelsson M, Kallioniemi OP, Walker-daniels J, Baileywilson JE, Beaty TH, Meyers DA, Walsh PC, Collins FS, Trent JM, Isaacs WB (1996) Major susceptibility locus for prostate cancer on chromosome 1 suggested by a genome-wide search. Science 274:1371-1374.
52. Stallings RL, Torney DC, Hildebrand CE, Longmire JL, Deaven LL, Jett JH, Doggett NA, Moyzis RK (1990) Physical mapping of human chromosomes by repetitive sequence fingerprinting. Proc Natl Acad Sci USA 87:6218-6222.
53. Steck PA, Pershouse MA, Jasser SA, Yung WKA, Lin H, Ligon AH, Langford LA, Baumgard ML, Hattier T, Davis T, Frye C, Hu R, Swedlund B, Teng DHF, Tavtigian SV (1997) Identification of a candidate tumour suppressor gene, Mmacl, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nature Genet 15:356-362.
54. Takahashi T, Takahashi T, Suzuki H, Hida T, Sekido Y, Ariyoshi Y, Ueda R (1991) The p53 gene is very frequently mutated in small-cell lung cancer with a distinct nucleotide substitution pattern. Oncogene 6:1775-1778.
55. Takeuchi S, Mori N, Koike M, Slater J, Park S, Miller C, Miyoshi I, Koeffler H (1996) Frequent loss of heterozygosity in the region of the KIP1 locus in non-small cell lung cancer: Evidence for a new tumour suppressor gene on the short arm of chromosome 12. Cancer Res 56:738-740.
56. Tamura K, Zhang X, Murakami Y, Hirohashi S, Xu HJ, Hu SX, Benedict WF, Sekiya T (1997) Deletion of three distinct regions on chromosome 13q in human non-small-cell lung cancer. Int J Cancer 74:45-19.
57. Tavassolj M, Steingrimsdottir H, Pierce E, Jiang X, Alagoz M, Farzaneh F, Campbell IG (1996) Loss of heterozygosity on chromosome 5q in ovarian cancer is frequently accompanied by TP53 mutation and identifies a tumour suppressor gene locus at 5q 13.1-21. Br J Cancer 74:115-119.
58. Thiberville L, Bourguignon J, Metayer J, Bost F, Diarra-Mehrpour M, Bignon J, Lam S, Martin JP, Nouvel G (1995) Frequency and prognostic evaluation of 3p 21-22 allelic losses in non-small-cell lung cancer. Int J Cancer 64:371-377.
59. Toguchida J, McGee TL, Paterson JC, Eagle JR, Tucker S, Yandell DW, Dryja TP (1993) Complete genomic sequence of the human retinoblastoma susceptibility gene. Genomics 17:535-543.
60. Tran YK, Newsham IF (1996) High-density marker analysis of 11p l5,5 In non-small cell lung carcinomas reveals allelic deletion of one shared and one distinct region when compared to breast carcinomas. Cancer Res 56:2916-2921.
61. Travis WD, Travis LB, Devesa SS (1995) Lung cancer. Cancer 75:191-202.
62. Tsuchiya E, Nakumura Y, Weng SY, Nakagawu K, Tsuchiya S, Sugano H, Kitagawa T (1992) Allelotype of non-small cell lung carcinoma -comparison between loss of heterozygosity in squamous cell carcinoma and adenocarcinoma. Cancer Res 52:2478-2481.
63. Vogelstein B, Fearon ER, Kern SE, Hamilton SR, Preisinger AC, Nakamura Y, White R (1989) Allelotype of colorectal carcinomas. Science 244:207-211.
64. Wick W, Petersen I, Schmutzler RK, Wolfarth B, Lenartz D, Bierhoff E, Hummerich J, Muller DJ, Stangl AP, Schramm J, Wiestler OD, von Deimling A (1996) Evidence for a novel tumor suppressor gene on chromosome 15 associated with progression to a metastatic stage in breast cancer. Oncogene 12:973-978.
65. Wieland I, Bohm M, Arden KC, Ammermuller T, Bogau S, Viars CS, Rajewsky MF (1996) Allelic deletion mapping on chromosome 5 in human carcinomas. Oncogene 12:97-102.
66. Wood S, Yaremko ML, Schertzer M, Kelemen PR, Minna J, Westbrook CA (1994) Mapping of the pulmonary surfactant SP5 (SFTP2) locus to Hp21 and characterization of a microsatellite repeat marker that shows frequent loss of heterozygosity in human carcinomas. Genomics 24:597-600.
67. Zervos AS, Gyuris J, Brent R (1993) Mxil, a protein that specifically interacts with Max to bind Myc-Max recognition sites [published erratum appears in Cell (1994) 2179: following 388]. Cell 72:223-232.
68. Zhang L, Zhou W, Velculescu VE, Kern SE, Hruban RH, Hamilton SR, Vogelsrein B, Kinzler KW (1997) Gene expression profiles in normal and cancer cells. Science 276:1268-1272.