Inhibition of cyclooxygenase-2 down-regulates aromatase activity and decreases proliferation of leydig tumor cells

Journal of Biological Chemistry

Volumn 284, Issue 42, 2009, Pages 28905-28916

  Sirianni, Rosa ^a   Chimento, Adele ^a   De Luca, Arianna ^a   Zolea, Fabiana ^a   Carpino, Amalia ^a   Rago, Vittoria ^a   Maggiolini, Marcello ^a   Andò, Sebastiano ^a   Pezzi, Vincenzo ^a  

^a UNIVERSITY OF CALABRIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATASE; CAMP-RESPONSE ELEMENT-BINDING PROTEINS; CYCLIN E; CYCLOOXYGENASE 2; INSULIN-LIKE GROWTH FACTOR-I; LEYDIG CELLS; OVER-EXPRESSION; PROSTAGLANDIN E2; PROTEIN KINASE A; SUBSEQUENT REDUCTION; TUMOR CELL LINES; TUMOR CELLS;

CELL CULTURE; CELL PROLIFERATION; FETAL MONITORING; PHOSPHORYLATION; TUMORS;

CELL MEMBRANES;

7 [5 (4 BIPHENYLYLMETHOXY) 2 MORPHOLINO 3 OXOCYCLOPENTYL] 4 HEPTENOIC ACID; AROMATASE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIN E; CYCLOOXYGENASE 2; ESTROGEN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E2;

ADULT; ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOGENESIS; CASE REPORT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; GENE SILENCING; HUMAN; HUMAN TISSUE; LEYDIG CELL TUMOR; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ADULT; ANIMALS; AROMATASE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INSULIN-LIKE GROWTH FACTOR I; LEYDIG CELLS; MALE; PHOSPHORYLATION; RATS; RATS, INBRED F344;

RATTUS;

EID: 70350365401     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.041020     Document Type: Article

References (61)

1. Hawkins, C., and Miaskowski, C. (1996) Oncol. Nurs. Forum 23, 1203-1211; quiz 1212-1213
2. Simpson, E. R., Mahendroo, M. S., Means, G. D., Kilgore, M. W., Hinshelwood, M. M., Graham-Lorence, S., Amarneh, B., Ito, Y., Fisher, C. R., and Michael, M. D. (1994) Endocr. Rev. 15, 342-355
3. Fowler, K. A., Gill, K., Kirma, N., Dillehay, D. L., and Tekmal, R. R. (2000) Am. J. Pathol. 156, 347-353
4. Sirianni, R., Chimento, A., Malivindi, R., Mazzitelli, I., Andò, S., and Pezzi, V. (2007) Cancer Res. 67, 8368-8377
5. Carpino, A., Rago, V., Pezzi, V., Carani, C., and Andò, S. (2007) Eur. J. Endocrinol. 157, 239-244
6. O'Donnell, L., Robertson, K. M., Jones, M. E., and Simpson, E. R. (2001) Endocr. Rev. 22, 289-318
7. Young, M., Lephart, E. D., and McPhaul, M. J. (1997) J. Steroid Biochem. Mol. Biol. 63, 37-44
8. Pezzi, V., Sirianni, R., Chimento, A., Maggiolini, M., Bourguiba, S., Delalande, C., Carreau, S., Andò, S., Simpson, E. R., and Clyne, C. D. (2004) Endocrinology 145, 2186-2196
9. Young, M., and McPhaul, M. J. (1998) Endocrinology 139, 5082-5093
10. Carlone, D. L., and Richards, J. S. (1997) Mol. Endocrinol. 11, 292-304
11. Song, K. H., Park, Y. Y., Park, K. C., Hong, C. Y., Park, J. H., Shong, M., Lee, K., and Choi, H. S. (2004) Mol. Endocrinol. 18, 1929-1940
12. Zhao, Y., Agarwal, V. R., Mendelson, C. R., and Simpson, E. R. (1996) Endocrinology 137, 5739-5742
13. Smith, W. L., and Marnett, L. J. (1991) Biochim. Biophys. Acta 1083, 1-17
14. Chandrasekharan, N. V., and Simmons, D. L. (2004) Genome Biol. 5, 241-247
15. Tsuji, S., Tsujii, M., Kawano, S., and Hori, M. (2001) J. Exp. Clin. Cancer Res. 20, 117-129
16. Sano, H., Kawahito, Y., Wilder, R. L., Hashiramoto, A., Mukai, S., Asai, K., Kimura, S., Kato, H., Kondo, M., and Hla, T. (1995) Cancer Res. 55, 3785-3789
17. Ristimäki, A., Honkanen, N., Jänkälä, H., Sipponen, P., and Härkönen, M. (1997) Cancer Res. 57, 1276-1280
18. Koga, H., Sakisaka, S., Ohishi, M., Kawaguchi, T., Taniguchi, E., Sasatomi, K., Harada, M., Kusaba, T., Tanaka, M., Kimura, R., Nakashima, Y., Nakashima, O., Kojiro, M., Kurohiji, T., and Sata, M. (1999) Hepatology 29, 688-696
19. Hida, T., Yatabe, Y., Achiwa, H., Muramatsu, H., Kozaki, K., Nakamura, S., Ogawa, M., Mitsudomi, T., Sugiura, T., and Takahashi, T. (1998) Cancer Res. 58, 3761-3764
20. Zimmermann, K. C., Sarbia, M., Weber, A. A., Borchard, F., Gabbert, H. E., and Schrör, K. (1999) Cancer Res. 59, 198-204
21. Tucker, O. N., Dannenberg, A. J., Yang, E. K., Zhang, F., Teng, L., Daly, J. M., Soslow, R. A., Masferrer, J. L., Woerner, B. M., Koki, A. T., and Fahey, T. J., 3rd (1999) Cancer Res. 59, 987-990
22. Hwang, D., Scollard, D., Byrne, J., and Levine, E. (1998) J. Natl. Cancer Inst. 90, 455-460
23. Brueggemeier, R. W., Quinn, A. L., Parrett, M. L., Joarder, F. S., Harris, R. E., and Robertson, F. M. (1999) Cancer Lett 140, 27-35
24. Díaz-Cruz, E. S., Shapiro, C. L., and Brueggemeier, R. W. (2005) J. Clin. Endocrinol. Metab. 90, 2563-2570
25. Prosperi, J. R., and Robertson, F. M. (2006) Prostaglandins Other Lipid Mediat. 81, 55-70
26. Frungieri, M. B., Weidinger, S., Meineke, V., Köhn, F. M., and Mayerhofer, A. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 15072-15077
27. Hase, T., Yoshimura, R., Matsuyama, M., Kawahito, Y., Wada, S., Tsuchida, K., Sano, H., and Nakatani, T. (2003) Eur. J. Cancer 39, 2043-2049
28. Coleman, G. L., Barthold, W., Osbaldiston, G. W., Foster, S. J., and Jonas, A. M. (1977) J. Gerontol. 32, 258-278
29. Davis, T. L., and Sharif, N. A. (2000) Br. J. Pharmacol. 130, 1919-1926
30. Woodward, D. F., Pepperl, D. J., Burkey, T. H., and Regan, J. W. (1995) Biochem. Pharmacol. 50, 1731-1733
31. Fulton, A. M., Zhang, S. Z., and Chong, Y. C. (1991) Cancer Res. 51, 2047-2050
32. Inoue, H., Tsujisawa, T., Fukuizumi, T., Kawagishi, S., and Uchiyama, C. (1999) J. Endocrinol. 161, 231-236
33. Chandras, C., Harris, T. E., Bernal, A. L., Abayasekara, D. R., and Michael, A. E. (2007) J. Endocrinol. 194, 595-602
34. Lephart, E. D., and Simpson, E. R. (1991) Methods Enzymol. 206, 477-483
35. Ristimäki, A., Sivula, A., Lundin, J., Lundin, M., Salminen, T., Haglund, C., Joensuu, H., and Isola, J. (2002) Cancer Res. 62, 632-635
36. Liu, C. H., Chang, S. H., Narko, K., Trifan, O. C., Wu, M. T., Smith, E., Haudenschild, C., Lane, T. F., and Hla, T. (2001) J. Biol. Chem. 276, 18563-18569
37. Alshafie, G. A., Abou-Issa, H. M., Seibert, K., and Harris, R. E. (2000) Oncol. Rep. 7, 1377-1381
38. Salhab, M., Singh-Ranger, G., Mokbel, R., Jouhra, F., Jiang, W. G., and Mokbel, K. (2007) J. Surg. Oncol. 96, 424-428
39. Simpson, E. R., Clyne, C., Rubin, G., Boon, W. C., Robertson, K., Britt, K., Speed, C., and Jones, M. (2002) Annu. Rev. Physiol. 64, 93-127
40. van Landeghem, A. A., Poortman, J., Nabuurs, M., and Thijssen, J. H. (1985) Cancer Res. 45, 2900-2906
41. Harada, N. (1997) J. Steroid Biochem. Mol. Biol. 61, 175-184
42. Agarwal, V. R., Bulun, S. E., Leitch, M., Rohrich, R., and Simpson, E. R. (1996) J. Clin. Endocrinol. Metab. 81, 3843-3849
43. Winnall, W. R., Ali, U., O'Bryan, M. K., Hirst, J. J., Whiley, P. A., Muir, J. A., and Hedger, M. P. (2007) Biol. Reprod. 76, 759-768
44. Gobbetti, A., and Zerani, M. (2002) J. Exp. Zool. 293, 73-80
45. Sheng, H., Shao, J., Washington, M. K., and DuBois, R. N. (2001) J. Biol. Chem. 276, 18075-18081
46. Coleman, R. A., Eglen, R. M., Jones, R. L., Narumiya, S., Shimizu, T., Smith, W. L., Dahlén, S. E., Drazen, J. M., Gardiner, P. J., Jackson, W. T., et al. (1995) Adv. Prostaglandin Thromboxane Leukot. Res. 23, 283-285
47. Breyer, R. M., Bagdassarian, C. K., Myers, S. A., and Breyer, M. D. (2001) Annu. Rev. Pharmacol. Toxicol. 41, 661-690
48. Richards, J. A., and Brueggemeier, R. W. (2003) J. Clin. Endocrinol. Metab. 88, 2010-2816
49. Balthazart, J., Baillien, M., Charlier, T. D., and Ball, G. F. (2003) Eur. J. Neurosci. 17, 1591-1606
50. Balthazart, J., Baillien, M., Charlier, T. D., Cornil, C. A., and Ball, G. F. (2003) J. Steroid Biochem. Mol Biol. 86, 367-379
51. Yue, W., Wang, J. P., Conaway, M. R., Li, Y., and Santen, R. J. (2003) J. Steroid Biochem. Mol. Biol. 86, 265-274
52. Su, B., Díaz-Cruz, E. S., Landini, S., and Brueggemeier, R. W. (2008) Steroids 73, 104-111
53. Pan, M. R., Chang, H. C., and Hung, W. C. (2008) Cell Signal. 20, 1134-1141
54. Dufau, M. L., Winters, C. A., Hattori, M., Aquilano D., Barañao, J. L., Nozu, K., Baukal, A., and Catt, K. J. (1984) J. Steroid Biochem. 20, 161-173
55. Ascoli, M. (2007) Mol. Cell Endocrinol. 260-262, 244-248
56. Jo, Y., King, S. R., Khan, S. A., and Stocco, D. M. (2005) Biol. Reprod. 73, 244-255
57. Bertagnolli, M. M., Eagle, C. J., Zauber, A. G., Redston, M., Solomon, S. D., Kim, K., Tang, J., Rosenstein, R. B., Corle, D., Hess, T. M., Woloj, G. M., Boisserie, F., Anderson, W. F., Viner, J. L., Bagheri, D., Burn, J., Chung, D. C., Dewar, T., Foley, T. R., Hoffman, N., Macrae, F., Pruitt, R. E., Saltzman, J. R., Salzberg, B., Sylwestrowicz, T., Gordon, G. B., and Hawk, E. T. (2006) N. Engl. J. Med. 355, 873-884
58. Farley, J. H., Truong, V., Goo, E., Uyehara, C., Belnap, C., and Larsen, W. I. (2006) Gynecol. Oncol. 103, 425-430
59. Stolina, M., Sharma, S., Lin, Y., Dohadwala, M., Gardner, B., Luo, J., Zhu, L., Kronenberg, M., Miller, P. W., Portanova, J., Lee, J. C., and Dubinett, S. M. (2000) J. Immunol. 164, 361-370
60. Chen, H., Luo, L., Liu, J., and Zirkin, B. R. (2007) Endocrinology 148, 735-742
61. Pedram, A., Razandi, M., Aitkenhead, M., Hughes, C. C., and Levin, E. R. (2002) J. Biol. Chem. 277, 50768-50775